Antibiotics and Antimicrobial Resistance Genes (AMR) in the Environment summarizes and updates information on antibiotic producing organisms and their resistance and entry routes in soil, air, water and sediment. As antibiotic use continues to rise in healthcare, their fate, bioavailability and biomonitoring, and impacts on environment and public health are becoming increasingly important. The book addresses the impact of antibiotics and AMR to environment and public health and risk assessment. Moreover, it focused on the metagenomics and molecular techniques for the detection of antibiotics and antimicrobial genes. Lastly, it introduces management strategies, such as treatment technologies for managing antibiotics and AMR/ARGs-impacted environment, and bioremediation approaches.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Contributors - p. xix 6. Acknowledgment - p. xxvii 7. Chapter 1. Microorganisms and antibiotic production - p. 1 8. Chapter 2. Antibiotics and antimicrobial resistance: temporal and global trends in the environment - p. 7 9. Chapter 3. Antibiotics’ presence in hospitals and associated wastes - p. 28 10. Chapter 4. Current trends of antimicrobials used in food animals and aquaculture - p. 39 11. Chapter 5. Major natural sinks for harboring microorganisms with altered antibiotic resistance versus major human contributing sources of antibiotic resistance: a detailed insight - p. 70 12. Chapter 6. Dissemination of antibiotic resistance in the environment - p. 99 13. Chapter 7. Long-range transport of antibiotics and AMR/ARGs - p. 117 14. Chapter 8. Antibiotics and antimicrobial resistance mechanism of entry in the environment - p. 126 15. Chapter 9. Antibiotics, AMRs, and ARGs: fate in the environment - p. 138 16. Chapter 10. On the edge of a precipice: the global emergence and dissemination of plasmid-borne mcr genes that confer resistance to colistin, a last-resort antibiotic - p. 155 17. Chapter 11. Uptake mechanism of antibiotics in plants - p. 183 18. Chapter 12. Modeling the spread of antibiotics and AMR/ARGs in soil - p. 189 19. Chapter 13. Metagenomics and methods development for the determination of antibiotics and AMR/ARGS - p. 195 20. Chapter 14. Global trends in ARGs measured by HT-qPCR platforms - p. 206 21. Chapter 15. Databases, multiplexed PCR, and next-generation sequencing technologies for tracking AMR genes in the environment - p. 223 22. Chapter 16. Toxicity of antibiotics - p. 234 23. Chapter 17. Carbapenems and Pseudomonas aeruginosa: mechanisms and epidemiology - p. 253 24. Chapter 18. Environmental and public health effects of antibiotics and AMR/ARGs - p. 269 25. Chapter 19. Antibiotics resistance mechanism - p. 292 26. Chapter 20. Microbial risk assessment and antimicrobial resistance - p. 313 27. Chapter 21. Environmental risk assessment of antibiotics and AMR/ARGs - p. 331 28. Chapter 22. Nanobiotechnology-based drug delivery strategy as a potential weapon against multiple drug-resistant pathogens - p. 350 29. Chapter 23. Treatment technologies and management options of antibiotics and AMR/ARGs - p. 369 30. Index - p. 395
Antibiotics and Antimicrobial Resistance Genes (AMR) in the Environment summarizes and updates information on antibiotic producing organisms and their resistance and entry routes in soil, air, water and sediment. As antibiotic use continues to rise in healthcare, their fate, bioavailability and biomonitoring, and impacts on environment and public health are becoming increasingly important. The book addresses the impact of antibiotics and AMR to environment and public health and risk assessment. Moreover, it focused on the metagenomics and molecular techniques for the detection of antibiotics and antimicrobial genes. Lastly, it introduces management strategies, such as treatment technologies for managing antibiotics and AMR/ARGs-impacted environment, and bioremediation approaches.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Contributors - p. xix 6. Acknowledgment - p. xxvii 7. Chapter 1. Microorganisms and antibiotic production - p. 1 8. Chapter 2. Antibiotics and antimicrobial resistance: temporal and global trends in the environment - p. 7 9. Chapter 3. Antibiotics’ presence in hospitals and associated wastes - p. 28 10. Chapter 4. Current trends of antimicrobials used in food animals and aquaculture - p. 39 11. Chapter 5. Major natural sinks for harboring microorganisms with altered antibiotic resistance versus major human contributing sources of antibiotic resistance: a detailed insight - p. 70 12. Chapter 6. Dissemination of antibiotic resistance in the environment - p. 99 13. Chapter 7. Long-range transport of antibiotics and AMR/ARGs - p. 117 14. Chapter 8. Antibiotics and antimicrobial resistance mechanism of entry in the environment - p. 126 15. Chapter 9. Antibiotics, AMRs, and ARGs: fate in the environment - p. 138 16. Chapter 10. On the edge of a precipice: the global emergence and dissemination of plasmid-borne mcr genes that confer resistance to colistin, a last-resort antibiotic - p. 155 17. Chapter 11. Uptake mechanism of antibiotics in plants - p. 183 18. Chapter 12. Modeling the spread of antibiotics and AMR/ARGs in soil - p. 189 19. Chapter 13. Metagenomics and methods development for the determination of antibiotics and AMR/ARGS - p. 195 20. Chapter 14. Global trends in ARGs measured by HT-qPCR platforms - p. 206 21. Chapter 15. Databases, multiplexed PCR, and next-generation sequencing technologies for tracking AMR genes in the environment - p. 223 22. Chapter 16. Toxicity of antibiotics - p. 234 23. Chapter 17. Carbapenems and Pseudomonas aeruginosa: mechanisms and epidemiology - p. 253 24. Chapter 18. Environmental and public health effects of antibiotics and AMR/ARGs - p. 269 25. Chapter 19. Antibiotics resistance mechanism - p. 292 26. Chapter 20. Microbial risk assessment and antimicrobial resistance - p. 313 27. Chapter 21. Environmental risk assessment of antibiotics and AMR/ARGs - p. 331 28. Chapter 22. Nanobiotechnology-based drug delivery strategy as a potential weapon against multiple drug-resistant pathogens - p. 350 29. Chapter 23. Treatment technologies and management options of antibiotics and AMR/ARGs - p. 369 30. Index - p. 395
