Ayurvedic Herbal Preparations in Neurological Disorders provides a comprehensive and mechanistic understanding of the therapeutic potential of many ayurvedic herbal preparations in disease management. Examining research data for evidence-based ayurvedic approaches, this volume begins with a focused introduction to major ayurvedic plants, discussing various mechanisms underlying their neuromodulatory potential in preclinical and clinical settings. Major subsets of ayurvedic plants are discussed, including Bacopa monnieri, Centella asiatica, Withania somnifera, and others. This volume outlines the importance of integrative approaches along with existing treatments in the intervention/management of Alzheimer’s disease, Parkinson’s disease, depressive mood disorders, epilepsy, schizophrenia, and more.
More than a mere compilation of studies, this volume identifies relevant gaps for future research avenues and encourages interdisciplinary collaboration and sharing of knowledge to together identify the most efficacious ayurvedic approaches. Highlighting recent developments (e.g., Ayurgenomics, Ayurahar) and other pertinent research for neuroprotection, this book is crucial for anyone researching or working in the field of neurological disorder treatment and prevention.
1. Ayurvedic Herbal Preparations in Neurological Disorders - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iv 6. Dedication - p. Page v 7. List of contributors - p. Page v 8. Preface - p. Page viii 9. Acknowledgments - p. Page xiii 10. List of Illustrations - p. Page xiv 11. List of Tables - p. Page xv 12. Chapter One : Ayurveda: Ayurvedic herbs against neurological disorders: are they golden nuggets? - p. Page xv 13. Chapter Two : Overview of approaches in ayurveda for neurological health and disorders - p. Page 31 14. Chapter Three : Therapeutic efficacy of ayurvedic polyherbal formulations (PHF): Interactive mechanisms and broad-spectrum activities against neurological disorders - p. Page 87 15. Chapter Four : Insights into the neuroprotective strategies to alleviate neurodegenerative conditions: Role of Ayurvedic herbs and their bioactives - p. Page 106 16. Chapter Five : Multiple broad spectrum Neuromodulatory effects of Bacopa monnieri and Centella asiatica: mechanistic considerations - p. Page 132 17. Chapter Six : Exploring the neuro-ameliorative propensity of Withania somnifera—Indian ginseng - p. Page 159 18. Chapter Seven : Acorus calamus in neurological disorders: a detailed overview - p. Page 184 19. Chapter Eight : Synaptic and mitochondrial alterations in traumatic brain injury (TBI): neuroprotective effects of phytochemicals and herbal products - p. Page 201 20. Chapter Nine : Dietary regulation of miRNAs involved in neurodegenerative diseases: role of nutraceuticals/Ayurvedic herbals - p. Page 217 21. Chapter Ten : Propensity of ayurvedic herbs as potential modulators of gut microbiome (GM): implications in neurological disorders - p. Page 262 22. Chapter Eleven : Genetic modulators of neurodegenerative diseases and their amelioration by natural products - p. Page 295 23. Chapter Twelve : Therapeutic propensity and pharmacological Action of herbal extract in Parkinson's Disease - p. Page 320 24. Chapter Thirteen : Phytochemicals for neurodegeneration and neuroinflammation: medicine of the future or a mirage? - p. Page 338 25. Chapter Fourteen : Ayurvedic herbs–derived cognitive enhancers for the management of Alzheimer's disease (AD) - p. Page 356 26. Chapter Fifteen : Role of ayurvedic herbs in the management of major depressive disorders (MDD) - p. Page 390 27. Chapter Sixteen : Mass spectrometry–based approaches for the identification of molecular mechanism of action of ayurvedic medicines in Parkinson disease - p. Page 417 28. Chapter Seventeen : Insights into the efficacy of Drosophila as a predictive preclinical model to understand the mechanism of neuroprotection of ayurvedic herbals - p. Page 449 29. Chapter Eighteen : Parkinson's Disease models of Caenorhabditis elegans to study mechanism of action of Ayurvedic nootropics - p. Page 480 30. Chapter Nineteen : Utilization of zebrafish as a preclinical model for obtaining insights into molecular mechanisms of the neuroprotective role of ayurvedic herbal preparations - p. Page 515 31. Chapter Twenty : Indian spices and their bioactives in neurological disorders - p. Page 535 32. Chapter Twenty One : Ayurveda herbs and herbal preparations in the management of neurological disorders - p. Page 565 33. Chapter Twenty Two : Yoga as a therapeutic intervention for the management of neurodegenerative disorders - p. Page 580 34. Chapter Twenty Three : Nanotechnology-enabled phytochemicals from Ayurvedic herbs for the treatment of neurodegenerative disorders: an overview - p. Page 604 35. Chapter Twenty Four : Neuroprotective potential of plant-based bioactive polysaccharides: molecular mechanisms and therapeutic advances - p. Page 627 36. Chapter Twenty Five : Ayurvedic science and herbaceuticals in neurological disorders: An overview of the current scenario; challenges and future perspectives - p. Page 657 37. Glossary - p. Page 685 38. Index - p. Page 692
Ayurvedic Herbal Preparations in Neurological Disorders provides a comprehensive and mechanistic understanding of the therapeutic potential of many ayurvedic herbal preparations in disease management. Examining research data for evidence-based ayurvedic approaches, this volume begins with a focused introduction to major ayurvedic plants, discussing various mechanisms underlying their neuromodulatory potential in preclinical and clinical settings. Major subsets of ayurvedic plants are discussed, including Bacopa monnieri, Centella asiatica, Withania somnifera, and others. This volume outlines the importance of integrative approaches along with existing treatments in the intervention/management of Alzheimer’s disease, Parkinson’s disease, depressive mood disorders, epilepsy, schizophrenia, and more.
More than a mere compilation of studies, this volume identifies relevant gaps for future research avenues and encourages interdisciplinary collaboration and sharing of knowledge to together identify the most efficacious ayurvedic approaches. Highlighting recent developments (e.g., Ayurgenomics, Ayurahar) and other pertinent research for neuroprotection, this book is crucial for anyone researching or working in the field of neurological disorder treatment and prevention.
1. Ayurvedic Herbal Preparations in Neurological Disorders - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iv 6. Dedication - p. Page v 7. List of contributors - p. Page v 8. Preface - p. Page viii 9. Acknowledgments - p. Page xiii 10. List of Illustrations - p. Page xiv 11. List of Tables - p. Page xv 12. Chapter One : Ayurveda: Ayurvedic herbs against neurological disorders: are they golden nuggets? - p. Page xv 13. Chapter Two : Overview of approaches in ayurveda for neurological health and disorders - p. Page 31 14. Chapter Three : Therapeutic efficacy of ayurvedic polyherbal formulations (PHF): Interactive mechanisms and broad-spectrum activities against neurological disorders - p. Page 87 15. Chapter Four : Insights into the neuroprotective strategies to alleviate neurodegenerative conditions: Role of Ayurvedic herbs and their bioactives - p. Page 106 16. Chapter Five : Multiple broad spectrum Neuromodulatory effects of Bacopa monnieri and Centella asiatica: mechanistic considerations - p. Page 132 17. Chapter Six : Exploring the neuro-ameliorative propensity of Withania somnifera—Indian ginseng - p. Page 159 18. Chapter Seven : Acorus calamus in neurological disorders: a detailed overview - p. Page 184 19. Chapter Eight : Synaptic and mitochondrial alterations in traumatic brain injury (TBI): neuroprotective effects of phytochemicals and herbal products - p. Page 201 20. Chapter Nine : Dietary regulation of miRNAs involved in neurodegenerative diseases: role of nutraceuticals/Ayurvedic herbals - p. Page 217 21. Chapter Ten : Propensity of ayurvedic herbs as potential modulators of gut microbiome (GM): implications in neurological disorders - p. Page 262 22. Chapter Eleven : Genetic modulators of neurodegenerative diseases and their amelioration by natural products - p. Page 295 23. Chapter Twelve : Therapeutic propensity and pharmacological Action of herbal extract in Parkinson's Disease - p. Page 320 24. Chapter Thirteen : Phytochemicals for neurodegeneration and neuroinflammation: medicine of the future or a mirage? - p. Page 338 25. Chapter Fourteen : Ayurvedic herbs–derived cognitive enhancers for the management of Alzheimer's disease (AD) - p. Page 356 26. Chapter Fifteen : Role of ayurvedic herbs in the management of major depressive disorders (MDD) - p. Page 390 27. Chapter Sixteen : Mass spectrometry–based approaches for the identification of molecular mechanism of action of ayurvedic medicines in Parkinson disease - p. Page 417 28. Chapter Seventeen : Insights into the efficacy of Drosophila as a predictive preclinical model to understand the mechanism of neuroprotection of ayurvedic herbals - p. Page 449 29. Chapter Eighteen : Parkinson's Disease models of Caenorhabditis elegans to study mechanism of action of Ayurvedic nootropics - p. Page 480 30. Chapter Nineteen : Utilization of zebrafish as a preclinical model for obtaining insights into molecular mechanisms of the neuroprotective role of ayurvedic herbal preparations - p. Page 515 31. Chapter Twenty : Indian spices and their bioactives in neurological disorders - p. Page 535 32. Chapter Twenty One : Ayurveda herbs and herbal preparations in the management of neurological disorders - p. Page 565 33. Chapter Twenty Two : Yoga as a therapeutic intervention for the management of neurodegenerative disorders - p. Page 580 34. Chapter Twenty Three : Nanotechnology-enabled phytochemicals from Ayurvedic herbs for the treatment of neurodegenerative disorders: an overview - p. Page 604 35. Chapter Twenty Four : Neuroprotective potential of plant-based bioactive polysaccharides: molecular mechanisms and therapeutic advances - p. Page 627 36. Chapter Twenty Five : Ayurvedic science and herbaceuticals in neurological disorders: An overview of the current scenario; challenges and future perspectives - p. Page 657 37. Glossary - p. Page 685 38. Index - p. Page 692
