There have been important developments in materials and therapies for the treatment of spinal conditions. Biomaterials for spinal surgery summarises this research and how it is being applied for the benefit of patients.
After an introduction to the subject, part one reviews fundamental issues such as spinal conditions and their pathologies, spinal loads, modelling and osteobiologic agents in spinal surgery. Part two discusses the use of bone substitutes and artificial intervertebral discs whilst part three covers topics such as the use of injectable biomaterials like calcium phosphate for vertebroplasty and kyphoplasty as well as scoliosis implants. The final part of the book summarises developments in regenerative therapies such as the use of stem cells for intervertebral disc regeneration.
With its distinguished editors and international team of contributors, Biomaterials for spinal surgery is a standard reference for both those developing new biomaterials and therapies for spinal surgery and those using them in clinical practice.
1. Chapter 1: Introduction to biomaterials for spinal surgery - p. xvii 2. Part I: Fundamentals of biomaterials for spinal surgery - p. 38 3. Chapter 2: An overview of the challenges of bringing a medical device for the spine to the market - p. 38 4. Chapter 3: Introduction to spinal pathologies and clinical problems of the spine - p. 77 5. Chapter 4: Forces on the spine - p. 113 6. Chapter 5: Finite element modelling of the spine - p. 143 7. Chapter 6: Osteobiologic agents in spine surgery - p. 232 8. Part II: Spinal fusion and intervertebral discs - p. 261 9. Chapter 7: Spine fusion: cages, plates and bone substitutes - p. 261 10. Chapter 8: Artificial intervertebral discs - p. 294 11. Chapter 9: Biological response to artificial discs - p. 312 12. Part III: Vertebroplasty and scoliosis surgery - p. 361 13. Chapter 10: The use of polymethyl methacrylate (PMMA) in neurosurgery - p. 361 14. Chapter 11: Optimising the properties of injectable materials for vertebroplasty and kyphoplasty - p. 384 15. Chapter 12: Injectable calcium phosphates for vertebral augmentation - p. 403 16. Chapter 13: Composite injectable materials for vertebroplasty - p. 413 17. Chapter 14: Scoliosis implants: surgical requirements - p. 431 18. Chapter 15: Shape memory, superelastic and low Young’s modulus alloys - p. 461 19. Part IV: Regenerative medicine in the spine - p. 490 20. Chapter 16: Cell-based tissue engineering approaches for disc regeneration - p. 490 21. Chapter 17: Angiogenesis control in spine regeneration - p. 509 22. Chapter 18: Stem cells for disc regeneration - p. 535 23. Chapter 19: Nucleus regeneration - p. 562 24. Chapter 20: In vivo models of regenerative medicine in the spine - p. 581 25. Index - p. 607
There have been important developments in materials and therapies for the treatment of spinal conditions. Biomaterials for spinal surgery summarises this research and how it is being applied for the benefit of patients.
After an introduction to the subject, part one reviews fundamental issues such as spinal conditions and their pathologies, spinal loads, modelling and osteobiologic agents in spinal surgery. Part two discusses the use of bone substitutes and artificial intervertebral discs whilst part three covers topics such as the use of injectable biomaterials like calcium phosphate for vertebroplasty and kyphoplasty as well as scoliosis implants. The final part of the book summarises developments in regenerative therapies such as the use of stem cells for intervertebral disc regeneration.
With its distinguished editors and international team of contributors, Biomaterials for spinal surgery is a standard reference for both those developing new biomaterials and therapies for spinal surgery and those using them in clinical practice.
1. Chapter 1: Introduction to biomaterials for spinal surgery - p. xvii 2. Part I: Fundamentals of biomaterials for spinal surgery - p. 38 3. Chapter 2: An overview of the challenges of bringing a medical device for the spine to the market - p. 38 4. Chapter 3: Introduction to spinal pathologies and clinical problems of the spine - p. 77 5. Chapter 4: Forces on the spine - p. 113 6. Chapter 5: Finite element modelling of the spine - p. 143 7. Chapter 6: Osteobiologic agents in spine surgery - p. 232 8. Part II: Spinal fusion and intervertebral discs - p. 261 9. Chapter 7: Spine fusion: cages, plates and bone substitutes - p. 261 10. Chapter 8: Artificial intervertebral discs - p. 294 11. Chapter 9: Biological response to artificial discs - p. 312 12. Part III: Vertebroplasty and scoliosis surgery - p. 361 13. Chapter 10: The use of polymethyl methacrylate (PMMA) in neurosurgery - p. 361 14. Chapter 11: Optimising the properties of injectable materials for vertebroplasty and kyphoplasty - p. 384 15. Chapter 12: Injectable calcium phosphates for vertebral augmentation - p. 403 16. Chapter 13: Composite injectable materials for vertebroplasty - p. 413 17. Chapter 14: Scoliosis implants: surgical requirements - p. 431 18. Chapter 15: Shape memory, superelastic and low Young’s modulus alloys - p. 461 19. Part IV: Regenerative medicine in the spine - p. 490 20. Chapter 16: Cell-based tissue engineering approaches for disc regeneration - p. 490 21. Chapter 17: Angiogenesis control in spine regeneration - p. 509 22. Chapter 18: Stem cells for disc regeneration - p. 535 23. Chapter 19: Nucleus regeneration - p. 562 24. Chapter 20: In vivo models of regenerative medicine in the spine - p. 581 25. Index - p. 607
