Dr. Spitzer has created an issue devoted to the evidence-based pharmacologic care of the neonate. The issue opens with an important article on A Quality Improvement Approach to Modifying Medication Use in the NICU. The expert authors he has secured have contributed articles in the areas of therapeutic drug monitoring, off-label use of medications in the NICU, antenatal and post-natal corticosteroids, antibiotics, antifungals, and antivirals, as well as bronchodilators and nitric oxide. Other articles also present evidence-based use of oxygen, dopamine, anesthetics and analgesics, and erythropoetin.
1. Cover - p. 1 2. Contributors - p. 2 3. Contents - p. 3 4. CME Accreditation Page and Author Disclosure - p. 4 5. Forthcoming Issues - p. 5 6. The Challenge of Managing Drugs Safely in the Newborn - p. 6 7. Preface - p. 7 8. A Quality Improvement Approach to Optimizing Medication Use in the Neonatal Intensive Care Unit - p. 8 9. Drug Studies in Newborns: A Therapeutic Imperative - p. 13 10. Therapeutic Drug Monitoring–the Appropriate Use of Drug Level Measurement in the Care of the Neonate - p. 21 11. Obstetric Interventions Beneficial to Prematurely Delivering Newborn Babies: Antenatal Corticostetroids, Progesterone, Magnesium Sulfate - p. 25 12. Evidence-Based Neonatal Pharmacotherapy: Postnatal Corticosteroids - p. 34 13. Antibiotic Use and Misuse in the Neonatal Intensive Care Unit - p. 43 14. The Use of Antiviral Drugs During the Neonatal Period - p. 48 15. The Use of Antifungal Therapy in Neonatal Intensive Care - p. 56 16. Metoclopramide, H2 Blockers, and Proton Pump Inhibitors: Pharmacotherapy for Gastroesophageal Reflux in Neonates - p. 65 17. Evidence-Based Use of Indomethacin and Ibuprofen in the Neonatal Intensive Care Unit - p. 72 18. Evidence-Based Methylxanthine Use in the NICU - p. 88 19. Pulmonary Vasodilator Therapy in the NICU: Inhaled Nitric Oxide, Sildenafil, and Other Pulmonary Vasodilating Agents - p. 94 20. The Use and Misuse of Oxygen During the Neonatal Period - p. 104 21. Hematological Interventions in NICU Care: the Use of rEpo, IVIG, and rG-CSF - p. 110 22. Management of Neonatal Thrombosis - p. 118 23. Neonatal Diuretic Therapy: Furosemide, Thiazides, and Spironolactone - p. 127 24. Neonatal Blood Pressure Support: The Use of Inotropes, Lusitropes, and Other Vasopressor Agents - p. 134 25. Anesthesia and Analgesia in the NICU - p. 144 26. Index - p. 153
Dr. Spitzer has created an issue devoted to the evidence-based pharmacologic care of the neonate. The issue opens with an important article on A Quality Improvement Approach to Modifying Medication Use in the NICU. The expert authors he has secured have contributed articles in the areas of therapeutic drug monitoring, off-label use of medications in the NICU, antenatal and post-natal corticosteroids, antibiotics, antifungals, and antivirals, as well as bronchodilators and nitric oxide. Other articles also present evidence-based use of oxygen, dopamine, anesthetics and analgesics, and erythropoetin.
1. Cover - p. 1 2. Contributors - p. 2 3. Contents - p. 3 4. CME Accreditation Page and Author Disclosure - p. 4 5. Forthcoming Issues - p. 5 6. The Challenge of Managing Drugs Safely in the Newborn - p. 6 7. Preface - p. 7 8. A Quality Improvement Approach to Optimizing Medication Use in the Neonatal Intensive Care Unit - p. 8 9. Drug Studies in Newborns: A Therapeutic Imperative - p. 13 10. Therapeutic Drug Monitoring–the Appropriate Use of Drug Level Measurement in the Care of the Neonate - p. 21 11. Obstetric Interventions Beneficial to Prematurely Delivering Newborn Babies: Antenatal Corticostetroids, Progesterone, Magnesium Sulfate - p. 25 12. Evidence-Based Neonatal Pharmacotherapy: Postnatal Corticosteroids - p. 34 13. Antibiotic Use and Misuse in the Neonatal Intensive Care Unit - p. 43 14. The Use of Antiviral Drugs During the Neonatal Period - p. 48 15. The Use of Antifungal Therapy in Neonatal Intensive Care - p. 56 16. Metoclopramide, H2 Blockers, and Proton Pump Inhibitors: Pharmacotherapy for Gastroesophageal Reflux in Neonates - p. 65 17. Evidence-Based Use of Indomethacin and Ibuprofen in the Neonatal Intensive Care Unit - p. 72 18. Evidence-Based Methylxanthine Use in the NICU - p. 88 19. Pulmonary Vasodilator Therapy in the NICU: Inhaled Nitric Oxide, Sildenafil, and Other Pulmonary Vasodilating Agents - p. 94 20. The Use and Misuse of Oxygen During the Neonatal Period - p. 104 21. Hematological Interventions in NICU Care: the Use of rEpo, IVIG, and rG-CSF - p. 110 22. Management of Neonatal Thrombosis - p. 118 23. Neonatal Diuretic Therapy: Furosemide, Thiazides, and Spironolactone - p. 127 24. Neonatal Blood Pressure Support: The Use of Inotropes, Lusitropes, and Other Vasopressor Agents - p. 134 25. Anesthesia and Analgesia in the NICU - p. 144 26. Index - p. 153
