Hepatitis C in Developing Countries: Current and Future Challenges explores the current state of HCV in several countries, including Africa, Asia and South America. It maintains a dedicated focus on the epidemiology, clinical patterns, virologic diversity, coinfections, natural history and progression, complications, and response to standard of care (SOC) pegylated interferon and ribavirin therapy of HCV with recommendations specific to middle and low income countries. Readers will find detailed information on the burden of HCV infection from a global health and economic perspective, along with data from multicenter trials on DAAs that have enrolled patients infected with HCV non-genotype 1.
1. Introduction - p. xv 2. Section 1. Hepatitis C Virus: Virology, Epidemiology, and Transmission - p. xvii 3. Chapter 1.1. Hepatitis C Virus: Virology and Genotypes - p. 3 4. Chapter 1.2. Epidemiology and Modes of Transmission of HCV in Developing Countries - p. 13 5. Section 2. The burden of Hepatitis C in Developing countries - p. 22 6. Chapter 2.1. Public Health and Economic Burden of Hepatitis C Infection in Developing Countries - p. 25 7. Chapter 2.2. Social, Cultural, and Political Factors Influencing HCV in Developing Countries - p. 33 8. Section 3. Hepatitis C Infection in Specific Geographic Regions - p. 38 9. Chapter 3.1. Hepatitis C in Egypt - p. 41 10. Chapter 3.2. Hepatitis C in North Africa (Arabic Maghreb Region) - p. 57 11. Chapter 3.3. Hepatitis C Virus in Sub-Saharan Africa - p. 71 12. Chapter 3.4. Hepatitis C Virus Infection in the Indian Sub-Continent - p. 83 13. Chapter 3.5. Hepatitis C in Developing Countries in Southeast Asia - p. 97 14. Section 4. Hepatitis C Coinfections and Comorbidities in Developing Countries - p. 104 15. Chapter 4.1. Hepatitis C and Schistosomiasis Coinfection - p. 107 16. Chapter 4.2. Hepatitis C and Helminthic Infections - p. 121 17. Chapter 4.3. Hepatitis C and HIV Coinfection in Developing Countries - p. 135 18. Chapter 4.4. Hepatitis B and C Coinfection - p. 157 19. Chapter 4.5. Hepatitis C Infection in Patients With Hemoglobinopathies - p. 177 20. Chapter 4.6. Hepatitis C in Patients on Hemodialysis - p. 191 21. Chapter 5. Hepatitis C Screening and Diagnosis in Developing Countries - p. 199 22. Section 5. Evolution of Hepatitis C Treatment - p. 206 23. Chapter 6. Hepatitis C Treatment in the Era of Direct-Acting Antiviral Agents: Challenges in Developing Countries - p. 209 24. Appendix - p. 247 25. Index - p. 253
Hepatitis C in Developing Countries: Current and Future Challenges explores the current state of HCV in several countries, including Africa, Asia and South America. It maintains a dedicated focus on the epidemiology, clinical patterns, virologic diversity, coinfections, natural history and progression, complications, and response to standard of care (SOC) pegylated interferon and ribavirin therapy of HCV with recommendations specific to middle and low income countries. Readers will find detailed information on the burden of HCV infection from a global health and economic perspective, along with data from multicenter trials on DAAs that have enrolled patients infected with HCV non-genotype 1.
1. Introduction - p. xv 2. Section 1. Hepatitis C Virus: Virology, Epidemiology, and Transmission - p. xvii 3. Chapter 1.1. Hepatitis C Virus: Virology and Genotypes - p. 3 4. Chapter 1.2. Epidemiology and Modes of Transmission of HCV in Developing Countries - p. 13 5. Section 2. The burden of Hepatitis C in Developing countries - p. 22 6. Chapter 2.1. Public Health and Economic Burden of Hepatitis C Infection in Developing Countries - p. 25 7. Chapter 2.2. Social, Cultural, and Political Factors Influencing HCV in Developing Countries - p. 33 8. Section 3. Hepatitis C Infection in Specific Geographic Regions - p. 38 9. Chapter 3.1. Hepatitis C in Egypt - p. 41 10. Chapter 3.2. Hepatitis C in North Africa (Arabic Maghreb Region) - p. 57 11. Chapter 3.3. Hepatitis C Virus in Sub-Saharan Africa - p. 71 12. Chapter 3.4. Hepatitis C Virus Infection in the Indian Sub-Continent - p. 83 13. Chapter 3.5. Hepatitis C in Developing Countries in Southeast Asia - p. 97 14. Section 4. Hepatitis C Coinfections and Comorbidities in Developing Countries - p. 104 15. Chapter 4.1. Hepatitis C and Schistosomiasis Coinfection - p. 107 16. Chapter 4.2. Hepatitis C and Helminthic Infections - p. 121 17. Chapter 4.3. Hepatitis C and HIV Coinfection in Developing Countries - p. 135 18. Chapter 4.4. Hepatitis B and C Coinfection - p. 157 19. Chapter 4.5. Hepatitis C Infection in Patients With Hemoglobinopathies - p. 177 20. Chapter 4.6. Hepatitis C in Patients on Hemodialysis - p. 191 21. Chapter 5. Hepatitis C Screening and Diagnosis in Developing Countries - p. 199 22. Section 5. Evolution of Hepatitis C Treatment - p. 206 23. Chapter 6. Hepatitis C Treatment in the Era of Direct-Acting Antiviral Agents: Challenges in Developing Countries - p. 209 24. Appendix - p. 247 25. Index - p. 253
