1. Introduction to Pathophysiology - p. xiii 2. Part One: Basic Concepts of Pathophysiology - p. xiv 3. Unit 1: The Cell - p. xiv 4. 1. Cellular Biology - p. 1 5. 2. Genes and Genetic Diseases - p. 38 6. 3. Epigenetics and Disease - p. 62 7. 4. Altered Cellular and Tissue Biology - p. 72 8. 5. Fluids and Electrolytes, Acids and Bases - p. 112 9. Unit 2: Mechanisms of Self-Defence - p. 132.e1 10. 6. Innate Immunity: Inflammation and Wound Healing - p. 133 11. 7. Adaptive Immunity - p. 157 12. 8. Infection and Defects in Mechanisms of Defence - p. 176 13. 9. Stress and Disease - p. 215 14. Unit 3: Cellular Proliferation: Cancer - p. 232.e1 15. 10. Biology of Cancer - p. 233 16. 11. Cancer Epidemiology - p. 266 17. 12. Cancer in Children and Adolescents - p. 294 18. Part Two: Body Systems and Diseases - p. 298.e1 19. Unit 4: The Neurological System - p. 298.e1 20. 13. Structure and Function of the Neurological System - p. 299 21. 14. Pain, Temperature, Sleep, and Sensory Function - p. 328 22. 15. Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function - p. 351 23. 16. Disorders of the Central and Peripheral Nervous Systems and Neuromuscular Junction - p. 382 24. 17. Developmental Alterations of Neurological Function - p. 411 25. Unit 5: The Endocrine System - p. 425.e1 26. 18. Mechanisms of Hormonal Regulation - p. 426 27. 19. Alterations of Hormonal Regulation - p. 447 28. Unit 6: The Hematological System - p. 476.e1 29. 20. Structure and Function of the Hematological System - p. 477 30. 21. Alterations of Hematological Function - p. 500 31. 22. Developmental Alterations of Hematological Function - p. 537 32. Unit 7: The Cardiovascular and Lymphatic Systems - p. 550.e1 33. 23. Structure and Function of the Cardiovascular and Lymphatic Systems - p. 551 34. 24. Alterations of Cardiovascular Function - p. 579 35. 25. Developmental Alterations of Cardiovascular Function - p. 637 36. Unit 8: The Pulmonary System - p. 652.e1 37. 26. Structure and Function of the Pulmonary System - p. 653 38. 27. Alterations of Pulmonary Function - p. 669 39. 28. Developmental Alterations of Pulmonary Function - p. 701 40. Unit 9: The Renal and Urological Systems - p. 712.e1 41. 29. Structure and Function of the Renal and Urological Systems - p. 713 42. 30. Alterations of Renal and Urinary Tract Function - p. 730 43. 31. Developmental Alterations of Renal and Urinary Tract Function - p. 756 44. Unit 10: The Reproductive Systems - p. 762.e1 45. 32. Structure and Function of the Reproductive Systems - p. 763 46. 33. Alterations of the Female Reproductive System - p. 785 47. 34. Alterations of the Male Reproductive System - p. 832 48. Unit 11: The Digestive System - p. 861 49. 35. Structure and Function of the Digestive System - p. 861 50. 36. Alterations of Digestive Function - p. 882 51. 37. Developmental Alterations of Digestive Function - p. 927 52. Unit 12: The Musculoskeletal and Integumentary Systems - p. 941.e1 53. 38. Structure and Function of the Musculoskeletal System - p. 942 54. 39. Alterations of Musculoskeletal Function - p. 964 55. 40. Developmental Alterations of Musculoskeletal Function - p. 1007 56. 41. Structure, Function, and Disorders of the Integument - p. 1021 57. 42. Developmental Alterations of the Integument - p. 1053 58. Appendix - p. 1070 59. Index - p. 1081 60. Prefixes and Suffixes used in Medical Terminology - p. 1128 61. Word Roots Commonly used in Medical Terminology - p. IBC1
1. Introduction to Pathophysiology - p. xiii 2. Part One: Basic Concepts of Pathophysiology - p. xiv 3. Unit 1: The Cell - p. xiv 4. 1. Cellular Biology - p. 1 5. 2. Genes and Genetic Diseases - p. 38 6. 3. Epigenetics and Disease - p. 62 7. 4. Altered Cellular and Tissue Biology - p. 72 8. 5. Fluids and Electrolytes, Acids and Bases - p. 112 9. Unit 2: Mechanisms of Self-Defence - p. 132.e1 10. 6. Innate Immunity: Inflammation and Wound Healing - p. 133 11. 7. Adaptive Immunity - p. 157 12. 8. Infection and Defects in Mechanisms of Defence - p. 176 13. 9. Stress and Disease - p. 215 14. Unit 3: Cellular Proliferation: Cancer - p. 232.e1 15. 10. Biology of Cancer - p. 233 16. 11. Cancer Epidemiology - p. 266 17. 12. Cancer in Children and Adolescents - p. 294 18. Part Two: Body Systems and Diseases - p. 298.e1 19. Unit 4: The Neurological System - p. 298.e1 20. 13. Structure and Function of the Neurological System - p. 299 21. 14. Pain, Temperature, Sleep, and Sensory Function - p. 328 22. 15. Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function - p. 351 23. 16. Disorders of the Central and Peripheral Nervous Systems and Neuromuscular Junction - p. 382 24. 17. Developmental Alterations of Neurological Function - p. 411 25. Unit 5: The Endocrine System - p. 425.e1 26. 18. Mechanisms of Hormonal Regulation - p. 426 27. 19. Alterations of Hormonal Regulation - p. 447 28. Unit 6: The Hematological System - p. 476.e1 29. 20. Structure and Function of the Hematological System - p. 477 30. 21. Alterations of Hematological Function - p. 500 31. 22. Developmental Alterations of Hematological Function - p. 537 32. Unit 7: The Cardiovascular and Lymphatic Systems - p. 550.e1 33. 23. Structure and Function of the Cardiovascular and Lymphatic Systems - p. 551 34. 24. Alterations of Cardiovascular Function - p. 579 35. 25. Developmental Alterations of Cardiovascular Function - p. 637 36. Unit 8: The Pulmonary System - p. 652.e1 37. 26. Structure and Function of the Pulmonary System - p. 653 38. 27. Alterations of Pulmonary Function - p. 669 39. 28. Developmental Alterations of Pulmonary Function - p. 701 40. Unit 9: The Renal and Urological Systems - p. 712.e1 41. 29. Structure and Function of the Renal and Urological Systems - p. 713 42. 30. Alterations of Renal and Urinary Tract Function - p. 730 43. 31. Developmental Alterations of Renal and Urinary Tract Function - p. 756 44. Unit 10: The Reproductive Systems - p. 762.e1 45. 32. Structure and Function of the Reproductive Systems - p. 763 46. 33. Alterations of the Female Reproductive System - p. 785 47. 34. Alterations of the Male Reproductive System - p. 832 48. Unit 11: The Digestive System - p. 861 49. 35. Structure and Function of the Digestive System - p. 861 50. 36. Alterations of Digestive Function - p. 882 51. 37. Developmental Alterations of Digestive Function - p. 927 52. Unit 12: The Musculoskeletal and Integumentary Systems - p. 941.e1 53. 38. Structure and Function of the Musculoskeletal System - p. 942 54. 39. Alterations of Musculoskeletal Function - p. 964 55. 40. Developmental Alterations of Musculoskeletal Function - p. 1007 56. 41. Structure, Function, and Disorders of the Integument - p. 1021 57. 42. Developmental Alterations of the Integument - p. 1053 58. Appendix - p. 1070 59. Index - p. 1081 60. Prefixes and Suffixes used in Medical Terminology - p. 1128 61. Word Roots Commonly used in Medical Terminology - p. IBC1