White matter lesions have been always challenging for general as well as neuroradiologits. Any disease process in the brain or body can affect white matter, making it very difficult to pinpoint the diagnosis. However the application of the proper algorithmic approach, pattern of distribution, and study of the morphology of these lesions makes it possible to limit the differential diagnosis and, many times, pinpoint specific diagnosis. Advancement of various imaging techniques predominately in MR (MR spectroscopy, MR perfusion, diffusion tensor imaging (DTI). functional MR) along with PET has further improved our understanding of these disease processes. However, most of these techniques are new and not well understood by every physician. This issue will cover the topics necessary to master these techniques.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Contributors - p. 4 5. CME Accreditation Page - p. 6 6. Forthcoming Issues - p. 7 7. Preface: Imaging of White Matter Lesions - p. 8 8. Chapter 1: Myelin, Myelination, and Corresponding Magnetic Resonance Imaging Changes - p. 9 9. Chapter 2: A Pattern Approach to Focal White Matter Hyperintensities on Magnetic Resonance Imaging - p. 16 10. Chapter 3: An Imaging Approach to Diffuse White Matter Changes - p. 25 11. Chapter 4: Imaging Manifestations of the Leukodystrophies, Inherited Disorders of White Matter - p. 34 12. Chapter 5: Advances in Multiple Sclerosis and its Variants - p. 56 13. Chapter 6: Secondary Demyelination Disorders and Destruction of White Matter - p. 67 14. Chapter 7: Viral Infections and White Matter Lesions - p. 78 15. Chapter 8: Neuroimaging of Vascular Dementia - p. 92 16. Chapter 9: Metabolic White Matter Diseases and the Utility of MR Spectroscopy - p. 102 17. Chapter 10: Diffusion Tensor Imaging of Cerebral White Matter - p. 107 18. Chapter 11: Imaging Approach to the Cord T2 Hyperintensity (Myelopathy) - p. 113 19. Index - p. 123
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White matter lesions have been always challenging for general as well as neuroradiologits. Any disease process in the brain or body can affect white matter, making it very difficult to pinpoint the diagnosis. However the application of the proper algorithmic approach, pattern of distribution, and study of the morphology of these lesions makes it possible to limit the differential diagnosis and, many times, pinpoint specific diagnosis. Advancement of various imaging techniques predominately in MR (MR spectroscopy, MR perfusion, diffusion tensor imaging (DTI). functional MR) along with PET has further improved our understanding of these disease processes. However, most of these techniques are new and not well understood by every physician. This issue will cover the topics necessary to master these techniques.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Contributors - p. 4 5. CME Accreditation Page - p. 6 6. Forthcoming Issues - p. 7 7. Preface: Imaging of White Matter Lesions - p. 8 8. Chapter 1: Myelin, Myelination, and Corresponding Magnetic Resonance Imaging Changes - p. 9 9. Chapter 2: A Pattern Approach to Focal White Matter Hyperintensities on Magnetic Resonance Imaging - p. 16 10. Chapter 3: An Imaging Approach to Diffuse White Matter Changes - p. 25 11. Chapter 4: Imaging Manifestations of the Leukodystrophies, Inherited Disorders of White Matter - p. 34 12. Chapter 5: Advances in Multiple Sclerosis and its Variants - p. 56 13. Chapter 6: Secondary Demyelination Disorders and Destruction of White Matter - p. 67 14. Chapter 7: Viral Infections and White Matter Lesions - p. 78 15. Chapter 8: Neuroimaging of Vascular Dementia - p. 92 16. Chapter 9: Metabolic White Matter Diseases and the Utility of MR Spectroscopy - p. 102 17. Chapter 10: Diffusion Tensor Imaging of Cerebral White Matter - p. 107 18. Chapter 11: Imaging Approach to the Cord T2 Hyperintensity (Myelopathy) - p. 113 19. Index - p. 123
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