Microglial Advances in Neurodegenerative Diseases, Volume 170 in the Advances in Immunology series, presents current developments and comprehensive reviews focused on the role of microglia and neuroinflammation in neurological and psychiatric disorders. This volume brings together contributions from leading researchers, offering up-to-date insights into microglial biology in health and disease, as well as their involvement in major neurodegenerative conditions. Chapters in this new release explore Cross-talk between Tau and Neuro-glia Axis of Alzheimer’s Disease, Microglia in Health and Disease, Amyloid-beta (Aβ) and Neuroinflammation in Microglia, Chemokine Receptor CX3CR1 Interacts with Tau and Regulates Microglial Activity in Alzheimer’s Disease, and much more.
Additional chapters explore Human-Induced Pluripotent Stem Cells in Psychiatric Disorders, GPCR-Mediated Internalization and Endosomal Sorting of the Tau–GPCR Complex in Microglia, iPSC-Derived Microglia: A Cellular Platform for Tau and Alzheimer’s Disease Immunotherapy, Advancements in Invasive and Non-Invasive Neuromodulation for Parkinson’s Disease, LRRK2-I1371V Disrupts Microglial Membrane Homeostasis and Enhances α-Synuclein Toxicity, Microglial Advances in Parkinson’s Disease, Microglial Advances in Alzheimer’s Disease, and more.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Series Page - p. iii 6. Copyright - p. iv 7. Contributors - p. xvii 8. Chapter One: Alzheimer’s disease: Extracellular Tau internalization in neuro-glial axis and its propagation mechanisms - p. 1 9. Chapter Two: Brain macrophages in neurodegeneration - p. 33 10. Chapter Three: Chemokine receptor CX3CR1 modulates microglial activity through Tau and amyloid-β interactions in Alzheimer’s disease - p. 83 11. Chapter Four: Human-induced pluripotent stem cells in psychiatric disorders: An inflammatory perspective - p. 109 12. Chapter Five: G-Protein coupled receptor-mediated internalization and endosomal sorting of Tau-GPCR complex in microglia - p. 147 13. Chapter Six: iPSC-derived neurospheres: A cellular platform for Tau and Alzheimer’s disease immunotherapy - p. 175 14. Chapter Seven: Harnessing neuromodulation to target microglial activity in neurodegenerative diseases - p. 205 15. Chapter Eight: Glial control of extracellular α-synuclein propagation in LRRK2 Parkinson’s disease - p. 215 16. Chapter Nine: Microglial advances in Parkinson’s disease - p. 247 17. Chapter Ten: Microglia in Alzheimer’s disease: Insights into disease progression and therapy - p. 283 18. Chapter Eleven: Microglia extracellular traps (MiETs) in Neurodegeneration: Mechanisms, Evidence Gaps, and Untapped Therapeutic Promise - p. 307 19. Chapter Twelve: Microglial polarisation imbalance and receptor-targeted therapeutics in Parkinson’s disease - p. 343 20. Chapter Thirteen: Microglial advances in psychiatric disorders - p. 371 21. Chapter Fourteen: Neuroinflammation and vaccination strategy in Parkinson’s disease - p. 401 22. Chapter Fifteen: Microglia-centered cellular crosstalk in neurodegeneration - p. 437
Microglial Advances in Neurodegenerative Diseases, Volume 170 in the Advances in Immunology series, presents current developments and comprehensive reviews focused on the role of microglia and neuroinflammation in neurological and psychiatric disorders. This volume brings together contributions from leading researchers, offering up-to-date insights into microglial biology in health and disease, as well as their involvement in major neurodegenerative conditions. Chapters in this new release explore Cross-talk between Tau and Neuro-glia Axis of Alzheimer’s Disease, Microglia in Health and Disease, Amyloid-beta (Aβ) and Neuroinflammation in Microglia, Chemokine Receptor CX3CR1 Interacts with Tau and Regulates Microglial Activity in Alzheimer’s Disease, and much more.
Additional chapters explore Human-Induced Pluripotent Stem Cells in Psychiatric Disorders, GPCR-Mediated Internalization and Endosomal Sorting of the Tau–GPCR Complex in Microglia, iPSC-Derived Microglia: A Cellular Platform for Tau and Alzheimer’s Disease Immunotherapy, Advancements in Invasive and Non-Invasive Neuromodulation for Parkinson’s Disease, LRRK2-I1371V Disrupts Microglial Membrane Homeostasis and Enhances α-Synuclein Toxicity, Microglial Advances in Parkinson’s Disease, Microglial Advances in Alzheimer’s Disease, and more.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Series Page - p. iii 6. Copyright - p. iv 7. Contributors - p. xvii 8. Chapter One: Alzheimer’s disease: Extracellular Tau internalization in neuro-glial axis and its propagation mechanisms - p. 1 9. Chapter Two: Brain macrophages in neurodegeneration - p. 33 10. Chapter Three: Chemokine receptor CX3CR1 modulates microglial activity through Tau and amyloid-β interactions in Alzheimer’s disease - p. 83 11. Chapter Four: Human-induced pluripotent stem cells in psychiatric disorders: An inflammatory perspective - p. 109 12. Chapter Five: G-Protein coupled receptor-mediated internalization and endosomal sorting of Tau-GPCR complex in microglia - p. 147 13. Chapter Six: iPSC-derived neurospheres: A cellular platform for Tau and Alzheimer’s disease immunotherapy - p. 175 14. Chapter Seven: Harnessing neuromodulation to target microglial activity in neurodegenerative diseases - p. 205 15. Chapter Eight: Glial control of extracellular α-synuclein propagation in LRRK2 Parkinson’s disease - p. 215 16. Chapter Nine: Microglial advances in Parkinson’s disease - p. 247 17. Chapter Ten: Microglia in Alzheimer’s disease: Insights into disease progression and therapy - p. 283 18. Chapter Eleven: Microglia extracellular traps (MiETs) in Neurodegeneration: Mechanisms, Evidence Gaps, and Untapped Therapeutic Promise - p. 307 19. Chapter Twelve: Microglial polarisation imbalance and receptor-targeted therapeutics in Parkinson’s disease - p. 343 20. Chapter Thirteen: Microglial advances in psychiatric disorders - p. 371 21. Chapter Fourteen: Neuroinflammation and vaccination strategy in Parkinson’s disease - p. 401 22. Chapter Fifteen: Microglia-centered cellular crosstalk in neurodegeneration - p. 437
