Widely recognized as the definitive text in pediatric cardiology, Moss and Adams' Heart Disease in Infants, Children, and Adolescents provides the authoritative, state-of-the-art information you need when caring for young patients with heart disease. The editorial team, led by Dr. Robert Shaddy, from Children's Hospital Los Angeles and the University of Southern California, ensures that you are kept fully up to date with recent advances in this complex and fast-changing field. This award-winning title, now in its Tenth Edition, continues to be the reference of choice for today’s cardiology fellows, pediatric cardiologists, and cardiology practitioners worldwide.
1. Cover - p. Cover 2. Title Page - p. i 3. Copyright - p. ii 4. Dedication - p. iii 5. Contributors - p. iii 6. Preface to the Previous Edition - p. xi 7. Preface - p. xii 8. Previous Editors - p. xiii 9. Contents - p. xv 10. Supplementary Video and eFigure - p. xviii 11. Section I: From the Gene to the Neonate - p. xviii 12. 1 Development of the Heart: Morphogenesis, Growth, and Molecular Regulation of Differentiation - p. 1 13. 2 Epidemiology and Prevention of Congenital Heart Defects - p. 54 14. 3 Genetic Aspects of Congenital Heart Defects - p. 84 15. 4 Development of Myocardial Structure and Function - p. 113 16. 5 Fetal and Perinatal Cardiology - p. 132 17. Section II: Structure and Function of the Cardiovascular System - p. 179 18. 6 Cardiac Anatomy and Examination of Cardiac Specimens - p. 179 19. 7 Classification and Terminology of Cardiovascular Anomalies - p. 209 20. 8 Cardiovascular Physiology - p. 230 21. Section III: Diagnostic and Therapeutic Methods - p. 243 22. 9 History and Physical Evaluation - p. 243 23. 10 Exercise Screening and Sports Participation - p. 251 24. 11 Exercise Stress Testing - p. 276 25. 12 Echocardiography: Basic Principles and Imaging - p. 293 26. 13 Echocardiographic Assessment of Cardiac Dimensions, Cardiac Function, and Valve Function - p. 328 27. 14 Magnetic Resonance Imaging - p. 361 28. 15 Cardiac Computed Tomography in Children with Congenital Heart Disease - p. 399 29. 16 Cardiac Catheterization and Angiography - p. 425 30. 17 Therapeutic Cardiac Catheterization - p. 454 31. Section IV: Electrophysiology - p. 509 32. 18 Anatomy of the Cardiac Conduction System in Congenital Heart Disease - p. 509 33. 19 The Normal Electrocardiogram - p. 517 34. 20 Cardiac Channelopathies, Syncope, and Sudden Cardiac Death - p. 534 35. 21 Electrophysiology Studies and Electrophysiologic Therapeutic Catheterization - p. 551 36. 22 Disorders of Cardiac Rhythm and Conduction - p. 586 37. Section V: Pediatric Cardiac Intensive Care - p. 617 38. 23 Physiology of the Preterm and Term Infant - p. 617 39. 24 Cardiovascular Intensive Care - p. 627 40. ORGANIZATION OF CARDIAC INTENSIVE CARE SERVICES - p. 627 41. EVALUATION AND MANAGEMENT OF THE CARDIOVASCULAR SYSTEM - p. 629 42. PREVENTION AND MANAGEMENT OF LOW CARDIAC OUTPUT SYNDROME - p. 633 43. ARRHYTHMIAS - p. 642 44. PULMONARY HYPERTENSION - p. 643 45. THE PULMONARY SYSTEM, VENTILATION, AND AIRWAY MANAGEMENT - p. 646 46. GENERAL POSTOPERATIVE CARE - p. 650 47. PERIOPERATIVE CONSIDERATIONS FOR SPECIFIC LESIONS AND PROCEDURES - p. 654 48. CENTRAL NERVOUS SYSTEM ISSUES - p. 660 49. THE RENAL SYSTEM - p. 664 50. FLUIDS, ELECTROLYTES, AND NUTRITION - p. 666 51. INFECTION IN THE CVICU - p. 668 52. ENDOCRINE ISSUES - p. 668 53. Adrenal Insufficiency and Corticosteroids - p. 668 54. Hypothyroidism - p. 669 55. CPR AND ECPR IN THE CVICU - p. 669 56. THE CATHETERIZATION LABORATORY AND THE CVICU - p. 669 57. MEDICAL CONDITIONS IN THE CVICU - p. 670 58. THE LOW–BIRTH-WEIGHT INFANT - p. 670 59. THE ADULT WITH CONGENITAL HEART DISEASE - p. 671 60. CONCLUSIONS - p. 671 61. 25 Mechanical Circulatory Support in Children - p. 678 62. 26 Cardiopulmonary and Right–Left Heart Interactions - p. 689 63. 27 Cardiac Trauma - p. 695 64. Section VI: Congenital Cardiovascular Malformations - p. 703 65. Part A: Septal Defects - p. 703 66. 28 Atrial Septal Defects - p. 703 67. 29 Atrioventricular Septal Defects - p. 721 68. 30 Ventricular Septal Defects - p. 746 69. Part B: Arterial Abnormalities - p. 765 70. 31 Patent Ductus Arteriosus and Aortopulmonary Window - p. 765 71. 32 Congenital Anomalies of the Coronary Vessels and the Aortic Root - p. 782 72. 33 Aortic Arch and Vascular Anomalies - p. 800 73. 34 Abnormalities of the Aortic Root - p. 837 74. Part C: Venous Abnormalities - p. 847 75. 35 Anomalies of the Pulmonary Veins - p. 847 76. 36 Abnormal Systemic Venous Connections - p. 877 77. 37 Vascular Tumors and Malformations - p. 899 78. Part D: The Right Ventricle - p. 914 79. 38 Tricuspid Valve Disorders: Atresia, Dysplasia, and Ebstein Anomaly - p. 914 80. 39 Pulmonary Stenosis - p. 940 81. 40 Pulmonary and Atresia Intact Ventricular Septum - p. 964 82. 41 Tetralogy of Fallot with Pulmonary Stenosis, Pulmonary Atresia, and Absent Pulmonary Valve - p. 983 83. 42 Truncus Arteriosus - p. 1009 84. Part E: Left Ventricular Inflow and Outflow Abnormalities - p. 1022 85. 43 Anatomical and Functional Mitral Valve Abnormalities in the Pediatric Population - p. 1022 86. 44 Aortic Stenosis - p. 1049 87. 45 Coarctation of the Aorta - p. 1067 88. 46 Hypoplastic Left Heart Syndrome - p. 1083 89. Part F: Abnormalities of the Origin of the Great Arteries - p. 1122 90. 47 Transposition of the Great Arteries - p. 1122 91. 48 Congenitally Corrected Transposition of the Great Arteries - p. 1145 92. 49 Double-Outlet Right Ventricle - p. 1159 93. Part G: Complex Cardiac Abnormalities - p. 1175 94. 50 Univentricular Atrioventricular Connection - p. 1175 95. 51 Cardiac Malpositions and Abnormalities of Atrial and Visceral Situs - p. 1195 96. Section VII: Diseases of the Endocardium, Myocardium, and Pericardium - p. 1221 97. 52 Hypertrophic Cardiomyopathy - p. 1221 98. 53 Dilated Cardiomyopathy - p. 1255 99. 54 Left Ventricular Noncompaction Cardiomyopathy - p. 1271 100. 55 Myocarditis - p. 1286 101. 56 Restrictive Cardiomyopathy - p. 1304 102. 57 The Heart in Muscular Dystrophies - p. 1315 103. 58 Kawasaki Disease (Mucocutaneous Lymph Node Syndrome) - p. 1328 104. 59 Rheumatic Fever and Rheumatic Heart Disease - p. 1348 105. 60 Inflammatory and Immune-Mediated Noninfectious Cardiovascular Diseases - p. 1373 106. 61 Pericardial Diseases - p. 1393 107. 62 Infective Endocarditis and Prevention - p. 1407 108. 63 Heart Transplantation - p. 1420 109. 64 Pathophysiology of Pulmonary Hypertension - p. 1440 110. Section VIII: Pulmonary Vascular Disease - p. 1475 111. 65 Pediatric Pulmonary Hypertension - p. 1475 112. 66 The Adolescent and Adult with Congenital Heart Disease - p. 1523 113. Section IX: Unique Issues Regarding the Young Adult with Congenital Heart Disease - p. 1571 114. 67 Transition to Adult Care - p. 1571 115. 68 Pregnancy in Young Women with Congenital Heart Disease - p. 1582 116. 69 Chest Pain in Children and Adolescents - p. 1596 117. Section X: Other Special Problems and Issues - p. 1601 118. 70 Coronary Risk Factors in Children - p. 1601 119. 71 Cardiac Tumors - p. 1635 120. 72 Chronic Heart Failure in Children - p. 1652 121. 73 Neurodevelopmental Outcomes after Heart Surgery in Children - p. 1674 122. 74 Hematologic Aspects of Pediatric and Adolescent Heart Disease: Bleeding, Clotting, and Blood Component Abnormalities - p. 1685 123. 75 The Fontan Circulation - p. 1708 124. 76 Evaluation of Quality of Life in Children and Adolescents with Congenital and Acquired Heart Disease - p. 1726 125. 77 Psychological Impact of Congenital Heart Disease: Key Timestamps and Clinical Strategies - p. 1742 126. 78 Safety and Quality in the Heart Center - p. 1750 127. 79 Global Challenge of Heart Disease - p. 1764 128. 80 Design, Execution, and Appraisal of Clinical Trials - p. 1777 129. 81 Pharmacology - p. 1800 130. Index - p. I-1
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Widely recognized as the definitive text in pediatric cardiology, Moss and Adams' Heart Disease in Infants, Children, and Adolescents provides the authoritative, state-of-the-art information you need when caring for young patients with heart disease. The editorial team, led by Dr. Robert Shaddy, from Children's Hospital Los Angeles and the University of Southern California, ensures that you are kept fully up to date with recent advances in this complex and fast-changing field. This award-winning title, now in its Tenth Edition, continues to be the reference of choice for today’s cardiology fellows, pediatric cardiologists, and cardiology practitioners worldwide.
1. Cover - p. Cover 2. Title Page - p. i 3. Copyright - p. ii 4. Dedication - p. iii 5. Contributors - p. iii 6. Preface to the Previous Edition - p. xi 7. Preface - p. xii 8. Previous Editors - p. xiii 9. Contents - p. xv 10. Supplementary Video and eFigure - p. xviii 11. Section I: From the Gene to the Neonate - p. xviii 12. 1 Development of the Heart: Morphogenesis, Growth, and Molecular Regulation of Differentiation - p. 1 13. 2 Epidemiology and Prevention of Congenital Heart Defects - p. 54 14. 3 Genetic Aspects of Congenital Heart Defects - p. 84 15. 4 Development of Myocardial Structure and Function - p. 113 16. 5 Fetal and Perinatal Cardiology - p. 132 17. Section II: Structure and Function of the Cardiovascular System - p. 179 18. 6 Cardiac Anatomy and Examination of Cardiac Specimens - p. 179 19. 7 Classification and Terminology of Cardiovascular Anomalies - p. 209 20. 8 Cardiovascular Physiology - p. 230 21. Section III: Diagnostic and Therapeutic Methods - p. 243 22. 9 History and Physical Evaluation - p. 243 23. 10 Exercise Screening and Sports Participation - p. 251 24. 11 Exercise Stress Testing - p. 276 25. 12 Echocardiography: Basic Principles and Imaging - p. 293 26. 13 Echocardiographic Assessment of Cardiac Dimensions, Cardiac Function, and Valve Function - p. 328 27. 14 Magnetic Resonance Imaging - p. 361 28. 15 Cardiac Computed Tomography in Children with Congenital Heart Disease - p. 399 29. 16 Cardiac Catheterization and Angiography - p. 425 30. 17 Therapeutic Cardiac Catheterization - p. 454 31. Section IV: Electrophysiology - p. 509 32. 18 Anatomy of the Cardiac Conduction System in Congenital Heart Disease - p. 509 33. 19 The Normal Electrocardiogram - p. 517 34. 20 Cardiac Channelopathies, Syncope, and Sudden Cardiac Death - p. 534 35. 21 Electrophysiology Studies and Electrophysiologic Therapeutic Catheterization - p. 551 36. 22 Disorders of Cardiac Rhythm and Conduction - p. 586 37. Section V: Pediatric Cardiac Intensive Care - p. 617 38. 23 Physiology of the Preterm and Term Infant - p. 617 39. 24 Cardiovascular Intensive Care - p. 627 40. ORGANIZATION OF CARDIAC INTENSIVE CARE SERVICES - p. 627 41. EVALUATION AND MANAGEMENT OF THE CARDIOVASCULAR SYSTEM - p. 629 42. PREVENTION AND MANAGEMENT OF LOW CARDIAC OUTPUT SYNDROME - p. 633 43. ARRHYTHMIAS - p. 642 44. PULMONARY HYPERTENSION - p. 643 45. THE PULMONARY SYSTEM, VENTILATION, AND AIRWAY MANAGEMENT - p. 646 46. GENERAL POSTOPERATIVE CARE - p. 650 47. PERIOPERATIVE CONSIDERATIONS FOR SPECIFIC LESIONS AND PROCEDURES - p. 654 48. CENTRAL NERVOUS SYSTEM ISSUES - p. 660 49. THE RENAL SYSTEM - p. 664 50. FLUIDS, ELECTROLYTES, AND NUTRITION - p. 666 51. INFECTION IN THE CVICU - p. 668 52. ENDOCRINE ISSUES - p. 668 53. Adrenal Insufficiency and Corticosteroids - p. 668 54. Hypothyroidism - p. 669 55. CPR AND ECPR IN THE CVICU - p. 669 56. THE CATHETERIZATION LABORATORY AND THE CVICU - p. 669 57. MEDICAL CONDITIONS IN THE CVICU - p. 670 58. THE LOW–BIRTH-WEIGHT INFANT - p. 670 59. THE ADULT WITH CONGENITAL HEART DISEASE - p. 671 60. CONCLUSIONS - p. 671 61. 25 Mechanical Circulatory Support in Children - p. 678 62. 26 Cardiopulmonary and Right–Left Heart Interactions - p. 689 63. 27 Cardiac Trauma - p. 695 64. Section VI: Congenital Cardiovascular Malformations - p. 703 65. Part A: Septal Defects - p. 703 66. 28 Atrial Septal Defects - p. 703 67. 29 Atrioventricular Septal Defects - p. 721 68. 30 Ventricular Septal Defects - p. 746 69. Part B: Arterial Abnormalities - p. 765 70. 31 Patent Ductus Arteriosus and Aortopulmonary Window - p. 765 71. 32 Congenital Anomalies of the Coronary Vessels and the Aortic Root - p. 782 72. 33 Aortic Arch and Vascular Anomalies - p. 800 73. 34 Abnormalities of the Aortic Root - p. 837 74. Part C: Venous Abnormalities - p. 847 75. 35 Anomalies of the Pulmonary Veins - p. 847 76. 36 Abnormal Systemic Venous Connections - p. 877 77. 37 Vascular Tumors and Malformations - p. 899 78. Part D: The Right Ventricle - p. 914 79. 38 Tricuspid Valve Disorders: Atresia, Dysplasia, and Ebstein Anomaly - p. 914 80. 39 Pulmonary Stenosis - p. 940 81. 40 Pulmonary and Atresia Intact Ventricular Septum - p. 964 82. 41 Tetralogy of Fallot with Pulmonary Stenosis, Pulmonary Atresia, and Absent Pulmonary Valve - p. 983 83. 42 Truncus Arteriosus - p. 1009 84. Part E: Left Ventricular Inflow and Outflow Abnormalities - p. 1022 85. 43 Anatomical and Functional Mitral Valve Abnormalities in the Pediatric Population - p. 1022 86. 44 Aortic Stenosis - p. 1049 87. 45 Coarctation of the Aorta - p. 1067 88. 46 Hypoplastic Left Heart Syndrome - p. 1083 89. Part F: Abnormalities of the Origin of the Great Arteries - p. 1122 90. 47 Transposition of the Great Arteries - p. 1122 91. 48 Congenitally Corrected Transposition of the Great Arteries - p. 1145 92. 49 Double-Outlet Right Ventricle - p. 1159 93. Part G: Complex Cardiac Abnormalities - p. 1175 94. 50 Univentricular Atrioventricular Connection - p. 1175 95. 51 Cardiac Malpositions and Abnormalities of Atrial and Visceral Situs - p. 1195 96. Section VII: Diseases of the Endocardium, Myocardium, and Pericardium - p. 1221 97. 52 Hypertrophic Cardiomyopathy - p. 1221 98. 53 Dilated Cardiomyopathy - p. 1255 99. 54 Left Ventricular Noncompaction Cardiomyopathy - p. 1271 100. 55 Myocarditis - p. 1286 101. 56 Restrictive Cardiomyopathy - p. 1304 102. 57 The Heart in Muscular Dystrophies - p. 1315 103. 58 Kawasaki Disease (Mucocutaneous Lymph Node Syndrome) - p. 1328 104. 59 Rheumatic Fever and Rheumatic Heart Disease - p. 1348 105. 60 Inflammatory and Immune-Mediated Noninfectious Cardiovascular Diseases - p. 1373 106. 61 Pericardial Diseases - p. 1393 107. 62 Infective Endocarditis and Prevention - p. 1407 108. 63 Heart Transplantation - p. 1420 109. 64 Pathophysiology of Pulmonary Hypertension - p. 1440 110. Section VIII: Pulmonary Vascular Disease - p. 1475 111. 65 Pediatric Pulmonary Hypertension - p. 1475 112. 66 The Adolescent and Adult with Congenital Heart Disease - p. 1523 113. Section IX: Unique Issues Regarding the Young Adult with Congenital Heart Disease - p. 1571 114. 67 Transition to Adult Care - p. 1571 115. 68 Pregnancy in Young Women with Congenital Heart Disease - p. 1582 116. 69 Chest Pain in Children and Adolescents - p. 1596 117. Section X: Other Special Problems and Issues - p. 1601 118. 70 Coronary Risk Factors in Children - p. 1601 119. 71 Cardiac Tumors - p. 1635 120. 72 Chronic Heart Failure in Children - p. 1652 121. 73 Neurodevelopmental Outcomes after Heart Surgery in Children - p. 1674 122. 74 Hematologic Aspects of Pediatric and Adolescent Heart Disease: Bleeding, Clotting, and Blood Component Abnormalities - p. 1685 123. 75 The Fontan Circulation - p. 1708 124. 76 Evaluation of Quality of Life in Children and Adolescents with Congenital and Acquired Heart Disease - p. 1726 125. 77 Psychological Impact of Congenital Heart Disease: Key Timestamps and Clinical Strategies - p. 1742 126. 78 Safety and Quality in the Heart Center - p. 1750 127. 79 Global Challenge of Heart Disease - p. 1764 128. 80 Design, Execution, and Appraisal of Clinical Trials - p. 1777 129. 81 Pharmacology - p. 1800 130. Index - p. I-1
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