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Nutrition in the Prevention and Treatment of Disease, Fourth Edition, is a compilation of current knowledge in clinical nutrition and an overview of the rationale and science base of its application to practice in the prevention and treatment of disease. In its fourth edition, this text continues the tradition of incorporating new discoveries and methods related to this important area of research

Generating and analyzing data that summarize dietary intake and its association with disease are valuable tasks in treating disease and developing disease prevention strategies. Well-founded medical nutrition therapies can minimize disease development and related complications. Providing scientifically sound, creative, and effective nutrition interventions is both challenging and rewarding.

  • Two new chapters on metabolomics and translational research, which have come to be used in nutrition research in recent years. The new areas of study are discussed with the perspective that the application of the scientific method is by definition an evolutionary process.
  • A new chapter on Genetics and Diabetes which reviews the latest research on causal genetic variants and biological mechanisms responsible for the disease, and explores potential interactions with environmental factors such as diet and lifestyle.
  • Includes all major "omics" – the exposome, metabolomics, genomics, and the gut microbiome.
  • Expands the microbiota portions to reflect complexity of diet on gut microbial ecology, metabolism and health

1. I Introduction - p. 5 2. II Dietary Assessment Methods - p. 5 3. III Dietary Assessment in Different Study Designs - p. 15 4. IV Dietary Assessment in Special Populations - p. 19 5. V Selected Issues in Dietary Assessment Methods - p. 23 6. Acknowledgments - p. 30 7. References - p. 30 8. Chapter 2. Assessment of Dietary Supplement Use - p. 49 9. Chapter 3. Physical and Clinical Assessment of Nutritional Status - p. 71 10. Chapter 4. Energy Requirement Methodology - p. 85 11. Chapter 5. Metabolomics - p. 103 12. Part B: Research and Applied Methods for Observational and Intervention Studies - p. 117 13. Chapter 6. Translational Research: Concepts and Methods in Dissemination and Implementation Research - p. 125 14. Chapter 7. Overview of Nutritional Epidemiology - p. 145 15. Chapter 8. Analysis, Presentation, and Interpretation of Dietary Data - p. 167 16. Chapter 9. Current Theoretical Bases for Nutrition Intervention and Their Uses - p. 185 17. Chapter 10. Nutrition Intervention: Lessons From Clinical Trials - p. 203 18. Chapter 11. Biomarkers and Their Use in Nutrition Intervention - p. 217 19. Section II: Nutrition for Health Maintenance, Prevention, and Disease-Specific Treatment - p. 230 20. Part A: Food and Nutrient Intake for Health - p. 230 21. Chapter 12. Nutrition Guidelines to Promote and Maintain Health - p. 239 22. Chapter 13. Nutritional Recommendations for Athletes - p. 255 23. Chapter 14. Nutrition for Children With Special Health Care Needs - p. 273 24. Part B: Dietary Bioactive Compounds for Health - p. 292 25. Chapter 15. Bioavailability and Metabolism of Bioactive Compounds From Foods - p. 301 26. Chapter 16. Antioxidants in Health and Disease - p. 321 27. Chapter 17. Choline and Brain Development - p. 347 28. Chapter 18. Dietary Phytochemicals in Neurodegenerative Disease - p. 361 29. Chapter 19. Diet and Supplements in the Prevention and Treatment of Eye Diseases - p. 393 30. Abstract - p. 393 31. I Introduction - p. 393 32. II Lutein, Zeaxanthin, and Eye Health Throughout the Lifespan - p. 394 33. III Cataract - p. 395 34. IV Age-Related Macular Degeneration - p. 400 35. V Diabetic Retinopathy - p. 410 36. VI Glaucoma - p. 415 37. VII Chapter Summary - p. 418 38. Acknowledgments - p. 418 39. References - p. 419 40. Chapter 20. Phytochemicals in the Prevention and Treatment of Obesity and Its Related Cancers - p. 435 41. Part C: Overweight and Obesity - p. 447 42. Chapter 21. Genetics of Nonsyndromic Human Obesity, With Suggestions for New Studies From Work in Mouse Models - p. 455 43. Chapter 22. Obesity: Overview of Medical Treatments and Interventions - p. 477 44. Chapter 23. Surgery for Severe Obesity - p. 499 45. Chapter 24. Behavioral Risk Factors for Overweight and Obesity: Diet and Physical Activity - p. 515 46. Chapter 25. Snacking and Energy Balance in Humans - p. 539 47. Part D: Cardiovascular Disease - p. 563 48. Chapter 26. Genetic Influences on Blood Lipids and Cardiovascular Disease Risk - p. 571 49. Chapter 27. The Role of Diet in the Prevention and Treatment of Cardiovascular Disease - p. 595 50. Chapter 28. Nutrition, Lifestyle, and Hypertension - p. 625 51. Part E: Diabetes Mellitus - p. 645 52. Chapter 29. Genetics and Diabetes - p. 659 53. Chapter 30. Obesity and the Risk for Type 2 Diabetes - p. 677 54. Chapter 31. The Role of Diet in the Prevention and Treatment of Diabetes - p. 691 55. Chapter 32. Nutritional Management for Gestational Diabetes - p. 709 56. Part F: Cancer - p. 726 57. Chapter 33. Interaction of Genetic Factors With Nutrition in Cancer - p. 733 58. Chapter 34. Nutrition and Cancers of the Breast, Endometrium, and Ovary - p. 749 59. Chapter 35. Nutrition and Prostate Cancer - p. 765 60. Chapter 36. Nutrition and Colon Cancer - p. 787 61. Part G: Gastrointestinal Health and Disease - p. 800 62. Chapter 37. Intestinal Microbiota and Diet in Health - p. 811 63. Chapter 38. Gut Microbial Metabolism in Health and Disease - p. 835 64. Chapter 39. Nutritional Management of Inflammatory Bowel Disease and Short Bowel Syndrome - p. 857 65. Chapter 40. Nutrient Considerations in Lactose Intolerance - p. 875 66. Chapter 41. Nutritional Considerations in the Management of Gluten-Related Disorders - p. 893 67. Chapter 42. Nutrition and Cystic Fibrosis - p. 911 68. Part H: Bone Health and Disease - p. 929 69. Chapter 43. Current Understanding of Vitamin D Metabolism, Nutritional Status, and Role in Disease Prevention - p. 937 70. Chapter 44. Osteoporosis: The Early Years - p. 969 71. Chapter 45. Osteoporosis in Adults - p. 991 72. Appendix - p. 1011 73. Index - p. 1027

Descripcion
Descripción

Nutrition in the Prevention and Treatment of Disease, Fourth Edition, is a compilation of current knowledge in clinical nutrition and an overview of the rationale and science base of its application to practice in the prevention and treatment of disease. In its fourth edition, this text continues the tradition of incorporating new discoveries and methods related to this important area of research

Generating and analyzing data that summarize dietary intake and its association with disease are valuable tasks in treating disease and developing disease prevention strategies. Well-founded medical nutrition therapies can minimize disease development and related complications. Providing scientifically sound, creative, and effective nutrition interventions is both challenging and rewarding.

  • Two new chapters on metabolomics and translational research, which have come to be used in nutrition research in recent years. The new areas of study are discussed with the perspective that the application of the scientific method is by definition an evolutionary process.
  • A new chapter on Genetics and Diabetes which reviews the latest research on causal genetic variants and biological mechanisms responsible for the disease, and explores potential interactions with environmental factors such as diet and lifestyle.
  • Includes all major "omics" – the exposome, metabolomics, genomics, and the gut microbiome.
  • Expands the microbiota portions to reflect complexity of diet on gut microbial ecology, metabolism and health

1. I Introduction - p. 5 2. II Dietary Assessment Methods - p. 5 3. III Dietary Assessment in Different Study Designs - p. 15 4. IV Dietary Assessment in Special Populations - p. 19 5. V Selected Issues in Dietary Assessment Methods - p. 23 6. Acknowledgments - p. 30 7. References - p. 30 8. Chapter 2. Assessment of Dietary Supplement Use - p. 49 9. Chapter 3. Physical and Clinical Assessment of Nutritional Status - p. 71 10. Chapter 4. Energy Requirement Methodology - p. 85 11. Chapter 5. Metabolomics - p. 103 12. Part B: Research and Applied Methods for Observational and Intervention Studies - p. 117 13. Chapter 6. Translational Research: Concepts and Methods in Dissemination and Implementation Research - p. 125 14. Chapter 7. Overview of Nutritional Epidemiology - p. 145 15. Chapter 8. Analysis, Presentation, and Interpretation of Dietary Data - p. 167 16. Chapter 9. Current Theoretical Bases for Nutrition Intervention and Their Uses - p. 185 17. Chapter 10. Nutrition Intervention: Lessons From Clinical Trials - p. 203 18. Chapter 11. Biomarkers and Their Use in Nutrition Intervention - p. 217 19. Section II: Nutrition for Health Maintenance, Prevention, and Disease-Specific Treatment - p. 230 20. Part A: Food and Nutrient Intake for Health - p. 230 21. Chapter 12. Nutrition Guidelines to Promote and Maintain Health - p. 239 22. Chapter 13. Nutritional Recommendations for Athletes - p. 255 23. Chapter 14. Nutrition for Children With Special Health Care Needs - p. 273 24. Part B: Dietary Bioactive Compounds for Health - p. 292 25. Chapter 15. Bioavailability and Metabolism of Bioactive Compounds From Foods - p. 301 26. Chapter 16. Antioxidants in Health and Disease - p. 321 27. Chapter 17. Choline and Brain Development - p. 347 28. Chapter 18. Dietary Phytochemicals in Neurodegenerative Disease - p. 361 29. Chapter 19. Diet and Supplements in the Prevention and Treatment of Eye Diseases - p. 393 30. Abstract - p. 393 31. I Introduction - p. 393 32. II Lutein, Zeaxanthin, and Eye Health Throughout the Lifespan - p. 394 33. III Cataract - p. 395 34. IV Age-Related Macular Degeneration - p. 400 35. V Diabetic Retinopathy - p. 410 36. VI Glaucoma - p. 415 37. VII Chapter Summary - p. 418 38. Acknowledgments - p. 418 39. References - p. 419 40. Chapter 20. Phytochemicals in the Prevention and Treatment of Obesity and Its Related Cancers - p. 435 41. Part C: Overweight and Obesity - p. 447 42. Chapter 21. Genetics of Nonsyndromic Human Obesity, With Suggestions for New Studies From Work in Mouse Models - p. 455 43. Chapter 22. Obesity: Overview of Medical Treatments and Interventions - p. 477 44. Chapter 23. Surgery for Severe Obesity - p. 499 45. Chapter 24. Behavioral Risk Factors for Overweight and Obesity: Diet and Physical Activity - p. 515 46. Chapter 25. Snacking and Energy Balance in Humans - p. 539 47. Part D: Cardiovascular Disease - p. 563 48. Chapter 26. Genetic Influences on Blood Lipids and Cardiovascular Disease Risk - p. 571 49. Chapter 27. The Role of Diet in the Prevention and Treatment of Cardiovascular Disease - p. 595 50. Chapter 28. Nutrition, Lifestyle, and Hypertension - p. 625 51. Part E: Diabetes Mellitus - p. 645 52. Chapter 29. Genetics and Diabetes - p. 659 53. Chapter 30. Obesity and the Risk for Type 2 Diabetes - p. 677 54. Chapter 31. The Role of Diet in the Prevention and Treatment of Diabetes - p. 691 55. Chapter 32. Nutritional Management for Gestational Diabetes - p. 709 56. Part F: Cancer - p. 726 57. Chapter 33. Interaction of Genetic Factors With Nutrition in Cancer - p. 733 58. Chapter 34. Nutrition and Cancers of the Breast, Endometrium, and Ovary - p. 749 59. Chapter 35. Nutrition and Prostate Cancer - p. 765 60. Chapter 36. Nutrition and Colon Cancer - p. 787 61. Part G: Gastrointestinal Health and Disease - p. 800 62. Chapter 37. Intestinal Microbiota and Diet in Health - p. 811 63. Chapter 38. Gut Microbial Metabolism in Health and Disease - p. 835 64. Chapter 39. Nutritional Management of Inflammatory Bowel Disease and Short Bowel Syndrome - p. 857 65. Chapter 40. Nutrient Considerations in Lactose Intolerance - p. 875 66. Chapter 41. Nutritional Considerations in the Management of Gluten-Related Disorders - p. 893 67. Chapter 42. Nutrition and Cystic Fibrosis - p. 911 68. Part H: Bone Health and Disease - p. 929 69. Chapter 43. Current Understanding of Vitamin D Metabolism, Nutritional Status, and Role in Disease Prevention - p. 937 70. Chapter 44. Osteoporosis: The Early Years - p. 969 71. Chapter 45. Osteoporosis in Adults - p. 991 72. Appendix - p. 1011 73. Index - p. 1027

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