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In consultation with Consulting Editor, Dr. Lucky Jain, Drs. Maximo Vento and Waldemar Carlo have put together a state-of the-art issue of the Clinics in Perinatology devoted to Perinatal Pharmacology. Clinical review articles are specifically devoted to the following: Monitoring and assessment of oxygenation in infants; Oxygen toxicity in neonates; New methods for non-invasive oxygen administration; Targeting oxygen in preterm and term infants starting at birth; Newborn resuscitation in settings without access to supplemental oxygen; Noninvasive versus invasive ventilatory support; Nasal SIMV versus Nasal CPAP before and after invasive ventilatory support; Is high-flow cannula inferior to CPAP for neonates?; Intermittent hypoxia: Importance; Closed-loop control of inspired oxygen in neonates: Compliance with targets; Meta-analysis oxygenation saturation targeting trials: Do infant subgroups matter?; Targets of oxygen saturation to optimize eye outcomes; Achieved oxygenation saturations and outcome in extremely preterm infants; Pulmonary hypertension in preterm infants; and Current recommendations and practice of oxygen therapy in preterm infants. Readers will come away with the latest information on oxygen therapy as they seek to utilize evidence-based recommendations to improve patient outcomes.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. CME Accreditation Page - p. xii 7. Forthcoming Issues - p. xiv 8. Foreword - p. xv 9. Preface - p. xvii 10. Noninvasive Monitoring and Assessment of Oxygenation in Infants - p. 417 11. Oxygen Toxicity in the Neonate: Thinking Beyond the Balance - p. 435 12. New Methods for Noninvasive Oxygen Administration - p. 449 13. Targeting Oxygen in Term and Preterm Infants Starting at Birth - p. 459 14. Newborn Resuscitation in Settings Without Access to Supplemental Oxygen - p. 475 15. Noninvasive Ventilation in the Age of Surfactant Administration - p. 493 16. Nasal Intermittent Mandatory Ventilation Versus Nasal Continuous Positive Airway Pressure Before and After Invasive Ventilatory Support - p. 517 17. Is Nasal High Flow Inferior to Continuous Positive Airway Pressure for Neonates? - p. 537 18. Intermittent Hypoxemia in Preterm Infants - p. 553 19. Targeting Arterial Oxygen Saturation by Closed-Loop Control of Inspired Oxygen in Preterm Infants - p. 567 20. Meta-analysis of Oxygenation Saturation Targeting Trials: Do Infant Subgroups Matter? - p. 579 21. Oxygen Saturation and Retinopathy of Prematurity - p. 593 22. Achieved Oxygenation Saturations and Outcome in Extremely Preterm Infants - p. 601 23. Oxygen Therapy and Pulmonary Hypertension in Preterm Infants - p. 611 24. Current Recommendations and Practice of Oxygen Therapy in Preterm Infants - p. 621

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In consultation with Consulting Editor, Dr. Lucky Jain, Drs. Maximo Vento and Waldemar Carlo have put together a state-of the-art issue of the Clinics in Perinatology devoted to Perinatal Pharmacology. Clinical review articles are specifically devoted to the following: Monitoring and assessment of oxygenation in infants; Oxygen toxicity in neonates; New methods for non-invasive oxygen administration; Targeting oxygen in preterm and term infants starting at birth; Newborn resuscitation in settings without access to supplemental oxygen; Noninvasive versus invasive ventilatory support; Nasal SIMV versus Nasal CPAP before and after invasive ventilatory support; Is high-flow cannula inferior to CPAP for neonates?; Intermittent hypoxia: Importance; Closed-loop control of inspired oxygen in neonates: Compliance with targets; Meta-analysis oxygenation saturation targeting trials: Do infant subgroups matter?; Targets of oxygen saturation to optimize eye outcomes; Achieved oxygenation saturations and outcome in extremely preterm infants; Pulmonary hypertension in preterm infants; and Current recommendations and practice of oxygen therapy in preterm infants. Readers will come away with the latest information on oxygen therapy as they seek to utilize evidence-based recommendations to improve patient outcomes.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. CME Accreditation Page - p. xii 7. Forthcoming Issues - p. xiv 8. Foreword - p. xv 9. Preface - p. xvii 10. Noninvasive Monitoring and Assessment of Oxygenation in Infants - p. 417 11. Oxygen Toxicity in the Neonate: Thinking Beyond the Balance - p. 435 12. New Methods for Noninvasive Oxygen Administration - p. 449 13. Targeting Oxygen in Term and Preterm Infants Starting at Birth - p. 459 14. Newborn Resuscitation in Settings Without Access to Supplemental Oxygen - p. 475 15. Noninvasive Ventilation in the Age of Surfactant Administration - p. 493 16. Nasal Intermittent Mandatory Ventilation Versus Nasal Continuous Positive Airway Pressure Before and After Invasive Ventilatory Support - p. 517 17. Is Nasal High Flow Inferior to Continuous Positive Airway Pressure for Neonates? - p. 537 18. Intermittent Hypoxemia in Preterm Infants - p. 553 19. Targeting Arterial Oxygen Saturation by Closed-Loop Control of Inspired Oxygen in Preterm Infants - p. 567 20. Meta-analysis of Oxygenation Saturation Targeting Trials: Do Infant Subgroups Matter? - p. 579 21. Oxygen Saturation and Retinopathy of Prematurity - p. 593 22. Achieved Oxygenation Saturations and Outcome in Extremely Preterm Infants - p. 601 23. Oxygen Therapy and Pulmonary Hypertension in Preterm Infants - p. 611 24. Current Recommendations and Practice of Oxygen Therapy in Preterm Infants - p. 621

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