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Spontaneous Pathology of the Laboratory Non-human Primate serves as a "go to" resource for all pathologists working on primates in safety assessment studies. In addition, it helps diagnostic veterinary pathologists rule out spontaneous non-clinical disease pathologies when assigning cause of death to species in zoological collections. Primate species included are rhesus, cynomolgus macaques and marmosets. Multi-authored chapters are arranged by organ system, thus providing the necessary information for continued research.Pathologists often face a lack of suitable reference materials or historical data to determine if pathologic changes they are observing in monkeys are spontaneous or a consequence of other treatments or factors.

  • Contains color illustrations that depict the most common lesions to augment descriptions
  • Covers descriptions that are compliant with the International Harmonization of Nomenclature and Diagnostic Criteria (INHAND) guidelines set forth by the Society of Toxicologic Pathology (STP)
  • Provides pathologists with common terms that are compliant with the FDA’s Standard for Exchange of Nonclinical Data (SEND) guidelines

1. Introduction - p. xviii 2. Chapter 1. Choice of the non-human primate for biomedical research - p. 1 3. Chapter 2. Regulations and ethics concerning the use of non-human primates in research - p. 7 4. Chapter 3. Infectious diseases of non-human primates - p. 15 5. Chapter 4. Clinical examination of the non-human primate - p. 71 6. Chapter 5. Routes of administration for the non-human primate - p. 75 7. Chapter 6. The alimentary system of the non-human primate - p. 83 8. Chapter 7. The hepatobiliary system of the non-human primate - p. 121 9. Chapter 8. The exocrine pancreas of the non-human primate - p. 147 10. Chapter 9. The urinary system of the non-human primate - p. 155 11. Chapter 10. The nervous system of the non-human primate - p. 185 12. Chapter 11. The eye and ocular adnexa of the non-human primate - p. 229 13. Chapter 12. Musculoskeletal system of the non-human primate - p. 279 14. Chapter 13. The integumentary system of the non-human primate - p. 299 15. Chapter 14. The mammary gland of the non-human primate - p. 327 16. Chapter 15. The respiratory system of the non-human primate - p. 339 17. Chapter 16. The hematolymphoid system of the non-human primate - p. 359 18. Chapter 17. The female reproductive tract of the non-human primate - p. 407 19. Chapter 18. The male reproductive system of the non-human primate - p. 437 20. Chapter 19. The cardiovascular system of the non-human primate - p. 459 21. Chapter 20. The endocrine system of the non-human primate - p. 487 22. Chapter 21. Clinical pathology of the non-human primate - p. 525 23. Chapter 22. Immunohistochemistry for the non-human primate - p. 553 24. Index - p. 587

Descripcion
Descripción

Spontaneous Pathology of the Laboratory Non-human Primate serves as a "go to" resource for all pathologists working on primates in safety assessment studies. In addition, it helps diagnostic veterinary pathologists rule out spontaneous non-clinical disease pathologies when assigning cause of death to species in zoological collections. Primate species included are rhesus, cynomolgus macaques and marmosets. Multi-authored chapters are arranged by organ system, thus providing the necessary information for continued research.Pathologists often face a lack of suitable reference materials or historical data to determine if pathologic changes they are observing in monkeys are spontaneous or a consequence of other treatments or factors.

  • Contains color illustrations that depict the most common lesions to augment descriptions
  • Covers descriptions that are compliant with the International Harmonization of Nomenclature and Diagnostic Criteria (INHAND) guidelines set forth by the Society of Toxicologic Pathology (STP)
  • Provides pathologists with common terms that are compliant with the FDA’s Standard for Exchange of Nonclinical Data (SEND) guidelines

1. Introduction - p. xviii 2. Chapter 1. Choice of the non-human primate for biomedical research - p. 1 3. Chapter 2. Regulations and ethics concerning the use of non-human primates in research - p. 7 4. Chapter 3. Infectious diseases of non-human primates - p. 15 5. Chapter 4. Clinical examination of the non-human primate - p. 71 6. Chapter 5. Routes of administration for the non-human primate - p. 75 7. Chapter 6. The alimentary system of the non-human primate - p. 83 8. Chapter 7. The hepatobiliary system of the non-human primate - p. 121 9. Chapter 8. The exocrine pancreas of the non-human primate - p. 147 10. Chapter 9. The urinary system of the non-human primate - p. 155 11. Chapter 10. The nervous system of the non-human primate - p. 185 12. Chapter 11. The eye and ocular adnexa of the non-human primate - p. 229 13. Chapter 12. Musculoskeletal system of the non-human primate - p. 279 14. Chapter 13. The integumentary system of the non-human primate - p. 299 15. Chapter 14. The mammary gland of the non-human primate - p. 327 16. Chapter 15. The respiratory system of the non-human primate - p. 339 17. Chapter 16. The hematolymphoid system of the non-human primate - p. 359 18. Chapter 17. The female reproductive tract of the non-human primate - p. 407 19. Chapter 18. The male reproductive system of the non-human primate - p. 437 20. Chapter 19. The cardiovascular system of the non-human primate - p. 459 21. Chapter 20. The endocrine system of the non-human primate - p. 487 22. Chapter 21. Clinical pathology of the non-human primate - p. 525 23. Chapter 22. Immunohistochemistry for the non-human primate - p. 553 24. Index - p. 587

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