Translational Biotechnology: A Journey from Laboratory to Clinics presents an integrative and multidisciplinary approach to biotechnology to help readers bridge the gaps between fundamental and functional research. The book provides state-of-the-art and integrative views of translational biotechnology by covering topics from basic concepts to novel methodologies. Topics discussed include biotechnology-based therapeutics, pathway and target discovery, biological therapeutic modalities, translational bioinformatics, and system and synthetic biology. Additional sections cover drug discovery, precision medicine and the socioeconomic impact of translational biotechnology. This book is valuable for bioinformaticians, biotechnologists, and members of the biomedical field who are interested in learning more about this promising field.
1. Chapter 11 Translational bioinformatics: An introduction - p. 289 2. Chapter 12 Pharmacodynamic biomarker for Hepatocellular carcinoma C: Model-based evaluation for pharmacokinetic–pharmacodynamic responses of drug - p. 311 3. Chapter 13 System biology and synthetic biology - p. 329 4. Chapter 14 Translational research in drug discovery: Tiny steps before the giant leap - p. 347 5. Chapter 15 FLAGSHIP: A novel drug discovery platform originating from the “dark matter of the genome” - p. 371 6. Chapter 16 Role of shared research facilities/core facilities in translational research - p. 383 7. Chapter 17 A new TOPSIS-based approach to evaluate the economic indicators in the healthcare system and the impact of biotechnology - p. 407 8. Index - p. 425
Translational Biotechnology: A Journey from Laboratory to Clinics presents an integrative and multidisciplinary approach to biotechnology to help readers bridge the gaps between fundamental and functional research. The book provides state-of-the-art and integrative views of translational biotechnology by covering topics from basic concepts to novel methodologies. Topics discussed include biotechnology-based therapeutics, pathway and target discovery, biological therapeutic modalities, translational bioinformatics, and system and synthetic biology. Additional sections cover drug discovery, precision medicine and the socioeconomic impact of translational biotechnology. This book is valuable for bioinformaticians, biotechnologists, and members of the biomedical field who are interested in learning more about this promising field.
1. Chapter 11 Translational bioinformatics: An introduction - p. 289 2. Chapter 12 Pharmacodynamic biomarker for Hepatocellular carcinoma C: Model-based evaluation for pharmacokinetic–pharmacodynamic responses of drug - p. 311 3. Chapter 13 System biology and synthetic biology - p. 329 4. Chapter 14 Translational research in drug discovery: Tiny steps before the giant leap - p. 347 5. Chapter 15 FLAGSHIP: A novel drug discovery platform originating from the “dark matter of the genome” - p. 371 6. Chapter 16 Role of shared research facilities/core facilities in translational research - p. 383 7. Chapter 17 A new TOPSIS-based approach to evaluate the economic indicators in the healthcare system and the impact of biotechnology - p. 407 8. Index - p. 425
