Year Book of Cardiology 2011

1. Cover - p. 1 2. Contents - p. 2 3. Limitations of the usual blood-pressure hypothesis and importance of variability, instability, and episodic hypertension - p. 8 4. Prognostic significance of visit-to-visit variability, maximum systolic blood pressure, and episodic hypertension - p. 9 5. Effects of antihypertensive-drug class on interindividual variation in blood pressure and risk of stroke: a systematic review and meta-analysis - p. 10 6. Effects of β blockers and calcium-channel blockers on within-individual variability in blood pressure and risk of stroke - p. 11 7. Management of High Blood Pressure in Blacks: An Update of the International Society on Hypertension in Blacks Consensus Statement - p. 12 8. Implications of Recently Published Trials of Blood Pressure–Lowering Drugs in Hypertensive or High-Risk Patients - p. 13 9. Treatment of hypertension in patients 80 years and older: the lower the better? A meta-analysis of randomized controlled trials - p. 14 10. Pre-eclampsia - p. 15 11. Antihypertensive Treatment and Development of Heart Failure in Hypertension: A Bayesian Network Meta-analysis of Studies in Patients With Hypertension and High Cardiovascular Risk - p. 16 12. Angiotensin-Converting Enzyme Inhibitor Associated Cough: Deceptive Information from the Physicians’ Desk Reference - p. 17 13. Efficacy of Revascularization For Renal Artery Stenosis Caused by Fibromuscular Dysplasia: A Systematic Review and Meta-Analysis - p. 18 14. Biofeedback for hypertension: a systematic review - p. 19 15. Does chocolate reduce blood pressure? A meta-analysis - p. 20 16. Angiotensin-receptor blockade and risk of cancer: meta-analysis of randomised controlled trials - p. 21 17. US Trends in Prevalence, Awareness, Treatment, and Control of Hypertension, 1988-2008 - p. 23 18. Use of angiotensin receptor blockers and risk of dementia in a predominantly male population: prospective cohort analysis - p. 24 19. Treatment with angiotensin receptor blockers before stroke could exert a favourable effect in acute cerebral infarction - p. 25 20. Long-term Blood Pressure Fluctuation and Cerebrovascular Disease in an Elderly Cohort - p. 26 21. Impact of the ALLHAT/JNC7 Dissemination Project on Thiazide-Type Diuretic Use - p. 27 22. Intensive Blood-Pressure Control in Hypertensive Chronic Kidney Disease - p. 28 23. Influence of Physicians’ Management and Communication Ability on Patients’ Persistence With Antihypertensive Medication - p. 29 24. Prevalence of Chronic Kidney Disease in Persons With Undiagnosed or Prehypertension in the United States - p. 30 25. Risk for Incident Atrial Fibrillation in Patients Who Receive Antihypertensive Drugs: A Nested Case–Control Study - p. 31 26. Definition of ambulatory blood pressure targets for diagnosis and treatment of hypertension in relation to clinic blood pressure: prospective cohort study - p. 32 27. Tight Blood Pressure Control and Cardiovascular Outcomes Among Hypertensive Patients With Diabetes and Coronary Artery Disease - p. 33 28. Myocardial infarction and stroke associated with diuretic based two drug antihypertensive regimens: population based case-control study - p. 34 29. Preeclampsia and Cardiovascular Disease Death: Prospective Evidence From the Child Health and Development Studies Cohort - p. 35 30. Lower Treatment Blood Pressure Is Associated With Greatest Reduction in Hematoma Growth After Acute Intracerebral Hemorrhage - p. 36 31. Projected Effect of Dietary Salt Reductions on Future Cardiovascular Disease - p. 37 32. Population Strategies to Decrease Sodium Intake and the Burden of Cardiovascular Disease: A Cost-Effectiveness Analysis - p. 38 33. Statins, antihypertensive treatment, and blood pressure control in clinic and over 24 hours: evidence from PHYLLIS randomised double blind trial - p. 39 34. Screening renal artery angiography in hypertensive patients undergoing coronary angiography and 6-month follow-up after ad hoc percutaneous revascularization - p. 40 35. Effects of Intensive Blood-Pressure Control in Type 2 Diabetes Mellitus - p. 41 36. Effect of Valsartan on the Incidence of Diabetes and Cardiovascular Events - p. 42 37. Target Blood Pressure for Treatment of Isolated Systolic Hypertension in the Elderly: Valsartan in Elderly Isolated Systolic Hypertension Study - p. 43 38. Renal outcomes with different fixed-dose combination therapies in patients with hypertension at high risk for cardiovascular events (ACCOMPLISH): a prespecified secondary analysis of a randomised controlled trial - p. 44 39. Cardiovascular Events During Differing Hypertension Therapies in Patients With Diabetes - p. 46 40. Effects of antihypertensive treatment after acute stroke in the Continue Or Stop post-Stroke Antihypertensives Collaborative Study (COSSACS): a prospective, randomised, open, blinded-endpoint trial - p. 47 41. Telemonitoring and self-management in the control of hypertension (TASMINH2): a randomised controlled trial - p. 48 42. Effect of self-measurement of blood pressure on adherence to treatment in patients with mild-to-moderate hypertension - p. 49 43. Continuous positive airway pressure treatment in sleep apnea patients with resistant hypertension: a randomized, controlled trial - p. 50 44. Efficacy of Spironolactone Therapy in Patients With True Resistant Hypertension - p. 51 45. Effects on Peripheral and Central Blood Pressure of Cocoa With Natural or High-Dose Theobromine: A Randomized, Double-Blind Crossover Trial - p. 52 46. Pharmacist-Physician Comanagement of Hypertension and Reduction in 24-Hour Ambulatory Blood Pressures - p. 53 47. Behavioral Neurocardiac Training in Hypertension: A Randomized, Controlled Trial - p. 54 48. Effects of the DASH Diet Alone and in Combination With Exercise and Weight Loss on Blood Pressure and Cardiovascular Biomarkers in Men and Women With High Blood Pressure: The ENCORE Study - p. 55 49. Effectiveness of a Barber-Based Intervention for Improving Hypertension Control in Black Men: The BARBER-1 Study: A Cluster Randomized Trial - p. 56 50. Vitamins C and E to Prevent Complications of Pregnancy-Associated Hypertension - p. 57 51. Effect of Sibutramine on Cardiovascular Outcomes in Overweight and Obese Subjects - p. 58 52. Chapter 2: Arrhythmia Burden in Adults With Surgically Repaired Tetralogy of Fallot: A Multi-Institutional Study - p. 59 53. Can we use the end systolic volume index to monitor intrinsic right ventricular function after repair of tetralogy of Fallot? - p. 60 54. Determinants of outcome after surgical treatment of pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries - p. 61 55. Cardiac Outcomes in Young Adult Survivors of the Arterial Switch Operation for Transposition of the Great Arteries - p. 62 56. Coronary Diameter and Vasodilator Function in Children Following Arterial Switch Operation for Complete Transposition of the Great Arteries - p. 63 57. Effects of Morphologic Left Ventricular Pressure on Right Ventricular Geometry and Tricuspid Valve Regurgitation in Patients With Congenitally Corrected Transposition of the Great Arteries - p. 64 58. Outcomes of Biventricular Repair for Congenitally Corrected Transposition of the Great Arteries - p. 65 59. Arrhythmias in a Contemporary Fontan Cohort: Prevalence and Clinical Associations in a Multicenter Cross-Sectional Study - p. 66 60. Exercise capacity, quality of life, and daily activity in the long-term follow-up of patients with univentricular heart and total cavopulmonary connection - p. 67 61. How Good Is a Good Fontan? Quality of Life and Exercise Capacity of Fontans Without Arrhythmias - p. 68 62. Improved management of systemic venous anomalies in a single ventricle: New rationale - p. 69 63. Laboratory Measures of Exercise Capacity and Ventricular Characteristics and Function Are Weakly Associated With Functional Health Status After Fontan Procedure - p. 70 64. A contemporary comparison of the effect of shunt type in hypoplastic left heart syndrome on the hemodynamics and outcome at Fontan completion - p. 71 65. Adults or Big Kids: What Is the Ideal Clinical Environment for Management of Grown-Up Patients With Congenital Heart Disease? - p. 72 66. Birth Before 39 Weeks’ Gestation Is Associated With Worse Outcomes in Neonates With Heart Disease - p. 73 67. Biventricular Repair of Atrioventricular Septal Defect With Common Atrioventricular Valve and Double-Outlet Right Ventricle - p. 74 68. Clinically silent preoperative brain injuries do not worsen with surgery in neonates with congenital heart disease - p. 75 69. Influence of Tracheobronchomalacia on Outcome of Surgery in Children With Congenital Heart Disease and Its Management - p. 76 70. Lesion-specific outcomes in neonates undergoing congenital heart surgery are related predominantly to patient and management factors rather than institution or surgeon experience: A Congenital Heart Surgeons Society Study - p. 77 71. Management and long-term outcome of neonatal Ebstein anomaly - p. 78 72. Selective Right Ventricular Unloading and Novel Technical Concepts in Ebstein’s Anomaly - p. 79 73. Cardiac outcomes after pregnancy in women with congenital heart disease - p. 80 74. Atrial septal defect: waiting for symptoms remains an unsolved medical anachronism - p. 81 75. Do Patients With Complete Transposition of the Great Arteries and Severe Pulmonary Hypertension Benefit From an Arterial Switch Operation? - p. 82 76. Assessment of Left Ventricular Endocardial Fibroelastosis in Fetuses With Aortic Stenosis and Evolving Hypoplastic Left Heart Syndrome - p. 83 77. Current Expectations for Surgical Repair of Isolated Ventricular Septal Defects - p. 84 78. Balloon expandable stent implantation for native and recurrent coarctation of the aorta—prospective computed tomography assessment of stent integrity, aneurysm formation and stenosis relief - p. 85 79. Do High-Risk Infants Have a Poorer Outcome From Primary Repair of Coarctation? Analysis of 192 Infants Over 20 Years - p. 86 80. Percutaneous closure of hypertensive ductus arteriosus - p. 87 81. Dilated cardiomyopathy in children with ventricular preexcitation: the location of the accessory pathway is predictive of this association - p. 88 82. Recommendations for cardiovascular magnetic resonance in adults with congenital heart disease from the respective working groups of the European Society of Cardiology - p. 89 83. Cardiac Operations After Patent Ductus Arteriosus Stenting in Duct-Dependent Pulmonary Circulation - p. 90 84. Clinical, echocardiographic and histopathologic findings in nine patients with surgically explanted ASD/PFO devices: Do we know enough about the healing process in humans? - p. 91 85. Increased Detection Rate of Kawasaki Disease Using New Diagnostic Algorithm, Including Early Use of Echocardiography - p. 92 86. Cardiovascular Abnormalities, Interventions, and Long-term Outcomes in Infantile Williams Syndrome - p. 93 87. Franklin H. Epstein Lecture. Cardiac Development and Implications for Heart Disease - p. 94 88. Cardiovascular Anomalies in Turner Syndrome: Spectrum, Prevalence, and Cardiac MRI Findings in a Pediatric and Young Adult Population - p. 95 89. Cerebrovascular accidents in adult patients with congenital heart disease - p. 96 90. Comparison of Clinical Presentations and Outcomes Between Patients With TGFBR2 and FBN1 Mutations in Marfan Syndrome and Related Disorders - p. 97 91. Equivalent Outcomes for Pediatric Heart Transplantation Recipients: ABO-Blood Group Incompatible versus ABO-Compatible - p. 98 92. Human Cord Blood Stem Cells Enhance Neonatal Right Ventricular Function in an Ovine Model of Right Ventricular Training - p. 99 93. Protective effect of periconceptional folic acid supplements on the risk of congenital heart defects: a registry-based case–control study in the northern Netherlands - p. 100 94. Chapter 3: Have hybrid procedures replaced open aortic arch reconstruction in high-risk patients? A comparative study of elective open arch debranching with endovascular stent graft placement and conventional elective open total and distal aortic arch reconstruction - p. 101 95. Spectrum and Outcome of Reoperations After the Ross Procedure - p. 102 96. Superior nationwide outcomes of endovascular versus open repair for isolated descending thoracic aortic aneurysm in 11,669 patients - p. 103 97. Importance of Refractory Pain and Hypertension in Acute Type B Aortic Dissection: Insights From the International Registry of Acute Aortic Dissection (IRAD) - p. 104 98. Surgical Management of Descending Thoracic Aortic Disease: Open and Endovascular Approaches: A Scientific Statement From the American Heart Association - p. 105 99. Aspirin Plus Clopidogrel Versus Aspirin Alone After Coronary Artery Bypass Grafting: The Clopidogrel After Surgery for Coronary Artery Disease (CASCADE) Trial - p. 106 100. Clinical Characteristics of Patients Undergoing Surgical Ventricular Reconstruction by Choice and by Randomization - p. 107 101. Comparable patencies of the radial artery and right internal thoracic artery or saphenous vein beyond 5 years: Results from the Radial Artery Patency and Clinical Outcomes trial - p. 108 102. Diabetic and Nondiabetic Patients With Left Main and/or 3-Vessel Coronary Artery Disease: Comparison of Outcomes With Cardiac Surgery and Paclitaxel-Eluting Stents - p. 109 103. Outcomes in Patients With De Novo Left Main Disease Treated With Either Percutaneous Coronary Intervention Using Paclitaxel-Eluting Stents or Coronary Artery Bypass Graft Treatment in the Synergy Between Percutaneous Coronary Intervention With TAXUS and Cardiac Surgery (SYNTAX) Trial - p. 110 104. Randomized trial to compare bilateral vs. single internal mammary coronary artery bypass grafting: 1-year results of the Arterial Revascularisation Trial (ART) - p. 111 105. Late Outcomes Following Freestyle Versus Homograft Aortic Root Replacement: Results From a Prospective Randomized Trial - p. 112 106. Outcomes of the RESTOR-MV Trial (Randomized Evaluation of a Surgical Treatment for Off-Pump Repair of the Mitral Valve) - p. 113 107. Should Patients With Severe Degenerative Mitral Regurgitation Delay Surgery Until Symptoms Develop? - p. 114 108. Transapical transcatheter aortic valve implantation: Follow-up to 3 years - p. 115 109. Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery - p. 116 110. A United Network for Organ Sharing analysis of heart transplantation in adults with congenital heart disease: Outcomes and factors associated with mortality and retransplantation - p. 117 111. Early and late outcomes of 517 consecutive adult patients treated with extracorporeal membrane oxygenation for refractory postcardiotomy cardiogenic shock - p. 118 112. Post–cardiac transplant survival after support with a continuous-flow left ventricular assist device: Impact of duration of left ventricular assist device support and other variables - p. 119 113. Right ventricular failure in patients with the HeartMate II continuous-flow left ventricular assist device: Incidence, risk factors, and effect on outcomes - p. 120 114. Where does atrial fibrillation surgery fail? Implications for increasing effectiveness of ablation - p. 121 115. Chapter 4: Association Between Timeliness of Reperfusion Therapy and Clinical Outcomes in ST-Elevation Myocardial Infarction - p. 122 116. Culprit Vessel Percutaneous Coronary Intervention Versus Multivessel and Staged Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction Patients With Multivessel Disease - p. 123 117. Early routine percutaneous coronary intervention after fibrinolysis vs. standard therapy in ST-segment elevation myocardial infarction: a meta-analysis - p. 124 118. Comparative Effectiveness of ST-Segment–Elevation Myocardial Infarction Regionalization Strategies - p. 125 119. Health Care Insurance, Financial Concerns in Accessing Care, and Delays to Hospital Presentation in Acute Myocardial Infarction - p. 126 120. Immediate Percutaneous Coronary Intervention Is Associated With Better Survival After Out-of-Hospital Cardiac Arrest: Insights From the PROCAT (Parisian Region Out of Hospital Cardiac Arrest) Registry - p. 127 121. Initial Clinical Results Using Intracardiac Electrogram Monitoring to Detect and Alert Patients During Coronary Plaque Rupture and Ischemia - p. 128 122. Lack of Effect of Oral Beta-Blocker Therapy at Discharge on Long-Term Clinical Outcomes of ST-Segment Elevation Acute Myocardial Infarction After Primary Percutaneous Coronary Intervention - p. 129 123. Primary angioplasty vs. fibrinolysis in very old patients with acute myocardial infarction: TRIANA (TRatamiento del Infarto Agudo de miocardio eN Ancianos) randomized trial and pooled analysis with previous studies - p. 130 124. Remote ischaemic conditioning before hospital admission, as a complement to angioplasty, and effect on myocardial salvage in patients with acute myocardial infarction: a randomised trial - p. 131 125. Right Ventricular Ischemic Injury in Patients With Acute ST-Segment Elevation Myocardial Infarction: Characterization With Cardiovascular Magnetic Resonance - p. 132 126. System Delay and Mortality Among Patients With STEMI Treated With Primary Percutaneous Coronary Intervention - p. 133 127. Trends in Door-to-Balloon Time and Mortality in Patients With ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention - p. 134 128. Treatments, Trends, and Outcomes of Acute Myocardial Infarction and Percutaneous Coronary Intervention - p. 135 129. When Is Door-to-Balloon Time Critical? Analysis From the HORIZONS-AMI (Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction) and CADILLAC (Controlled Abciximab and Device Investigation to Lower Late Angioplasty Complications) Trials - p. 136 130. Early Reperfusion During Acute Myocardial Infarction Affects Ventricular Tachycardia Characteristics and the Chronic Electroanatomic and Histological Substrate - p. 137 131. Adherence of Catheterization Laboratory Cardiologists to American College of Cardiology/American Heart Association Guidelines for Percutaneous Coronary Interventions and Coronary Artery Bypass Graft Surgery: What Happens in Actual Practice? - p. 138 132. Angiographic Versus Functional Severity of Coronary Artery Stenoses in the FAME Study: Fractional Flow Reserve Versus Angiography in Multivessel Evaluation - p. 139 133. Diabetic and Nondiabetic Patients With Left Main and/or 3-Vessel Coronary Artery Disease: Comparison of Outcomes With Cardiac Surgery and Paclitaxel-Eluting Stents - p. 140 134. Single-Photon Emission Computed Tomography Myocardial Perfusion Imaging and the Risk of Sudden Cardiac Death in Patients With Coronary Disease and Left Ventricular Ejection Fraction >35% - p. 141 135. No Major Differences in 30-Day Outcomes in High-Risk Patients Randomized to Off-Pump Versus On-Pump Coronary Bypass Surgery: The Best Bypass Surgery Trial - p. 142 136. Percutaneous Revascularization for Stable Coronary Artery Disease: Temporal Trends and Impact of Drug-Eluting Stents - p. 143 137. Outcomes in Patients With De Novo Left Main Disease Treated With Either Percutaneous Coronary Intervention Using Paclitaxel-Eluting Stents or Coronary Artery Bypass Graft Treatment in the Synergy Between Percutaneous Coronary Intervention With TAXUS and Cardiac Surgery (SYNTAX) Trial - p. 144 138. Ten-Year Follow-Up Survival of the Medicine, Angioplasty, or Surgery Study (MASS II): A Randomized Controlled Clinical Trial of 3 Therapeutic Strategies for Multivessel Coronary Artery Disease - p. 145 139. Duration of Dual Antiplatelet Therapy after Implantation of Drug-Eluting Stents - p. 146 140. Effect of high-dose allopurinol on exercise in patients with chronic stable angina: a randomised, placebo controlled crossover trial - p. 147 141. Safety of Anacetrapib in Patients with or at High Risk for Coronary Heart Disease - p. 148 142. Association of Marine Omega-3 Fatty Acid Levels With Telomeric Aging in Patients With Coronary Heart Disease - p. 149 143. Alcohol Consumption and Cardiovascular Mortality Among U.S. Adults, 1987 to 2002 - p. 150 144. Alcohol Intake and Risk of Coronary Heart Disease in Younger, Middle-Aged, and Older Adults - p. 151 145. Attained Educational Level and Incident Atherothrombotic Events in Low- and Middle-Income Compared With High-Income Countries - p. 152 146. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials - p. 153 147. Orthostatic hypotension predicts all-cause mortality and coronary events in middle-aged individuals (The Malmö Preventive Project) - p. 154 148. Outcomes After Acute Myocardial Infarction in South Asian, Chinese, and White Patients - p. 155 149. Population Trends in the Incidence and Outcomes of Acute Myocardial Infarction - p. 156 150. Prospective Study of Obstructive Sleep Apnea and Incident Coronary Heart Disease and Heart Failure: The Sleep Heart Health Study - p. 157 151. Sociodemographic patterning of non-communicable disease risk factors in rural India: a cross sectional study - p. 158 152. Thirty-five-year trends in cardiovascular risk factors in Finland - p. 159 153. Trends in Incidence, Severity, and Outcome of Hospitalized Myocardial Infarction - p. 160 154. HDL cholesterol and residual risk of first cardiovascular events after treatment with potent statin therapy: an analysis from the JUPITER trial - p. 161 155. Projected Effect of Dietary Salt Reductions on Future Cardiovascular Disease - p. 162 156. Myocardial Infarction and Risk of Suicide: A Population-Based Case-Control Study - p. 163 157. Relationship Between Cardiac Rehabilitation and Long-Term Risks of Death and Myocardial Infarction Among Elderly Medicare Beneficiaries - p. 164 158. Enhanced External Counterpulsation Improves Peripheral Artery Flow-Mediated Dilation in Patients With Chronic Angina: A Randomized sham-Controlled Study - p. 165 159. Low Diagnostic Yield of Elective Coronary Angiography - p. 166 160. Meta-analysis: Effects of Percutaneous Coronary Intervention Versus Medical Therapy on Angina Relief - p. 167 161. Effect of Sibutramine on Cardiovascular Outcomes in Overweight and Obese Subjects - p. 168 162. Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials - p. 169 163. Don’t worry, be happy: positive affect and reduced 10-year incident coronary heart disease: The Canadian Nova Scotia Health Survey - p. 170 164. Etiology of sudden death in the community: Results of anatomical, metabolic, and genetic evaluation - p. 171 165. Exercise Capacity and Mortality in Older Men: A 20-Year Follow-Up Study - p. 172 166. Neighborhood Socioeconomic Context and Long-Term Survival After Myocardial Infarction - p. 173 167. Comparison of ticagrelor with clopidogrel in patients with a planned invasive strategy for acute coronary syndromes (PLATO): a randomized double-blind study - p. 174 168. Impact of Delay to Angioplasty in Patients With Acute Coronary Syndromes Undergoing Invasive Management: Analysis From the ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) Trial - p. 175 169. Long-Term Outcome of a Routine Versus Selective Invasive Strategy in Patients With Non–ST-Segment Elevation Acute Coronary Syndrome A Meta-Analysis of Individual Patient Data - p. 176 170. Relationship between baseline hemoglobin and major bleeding complications in acute coronary syndromes - p. 177 171. Timing of In-Hospital Coronary Artery Bypass Graft Surgery for Non–ST-Segment Elevation Myocardial Infarction Patients: Results From the National Cardiovascular Data Registry ACTION Registry–GWTG (Acute Coronary Treatment and Intervention Outcomes Network Registry–Get With The Guidelines) - p. 178 172. Relationship of Thrombus Healing to Underlying Plaque Morphology in Sudden Coronary Death - p. 179 173. Chapter 5: 2010 Focused Update of ESC Guidelines on device therapy in heart failure: An update of the 2008 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure and the 2007 ESC guidelines for cardiac and resynchronization therapy: Developed with the special contribution of the Heart Failure Association and the European Heart Rhythm Association - p. 180 174. A randomized double-blind comparison of biventricular versus left ventricular stimulation for cardiac resynchronization therapy: The Biventricular versus Left Univentricular Pacing with ICD Back-up in Heart Failure Patients (B-LEFT HF) trial - p. 181 175. Cardiac Resynchronization Induces Major Structural and Functional Reverse Remodeling in Patients With New York Heart Association Class I/II Heart Failure - p. 182 176. Characteristics of heart failure patients associated with good and poor response to cardiac resynchronization therapy: a PROSPECT (Predictors of Response to CRT) sub-analysis - p. 183 177. Impact of reduction in early- and late-systolic functional mitral regurgitation on reverse remodelling after cardiac resynchronization therapy - p. 184 178. Presence of left ventricular contractile reserve predicts midterm response to cardiac resynchronization therapy—results from the LOw dose DObutamine Stress-Echo Test in Cardiac Resynchronization Therapy (LODO-CRT) Trial - p. 185 179. Relationship of Echocardiographic Dyssynchrony to Long-Term Survival After Cardiac Resynchronization Therapy - p. 186 180. Ultrafiltration is Associated With Fewer Rehospitalizations than Continuous Diuretic Infusion in Patients With Decompensated Heart Failure: Results From UNLOAD - p. 187 181. Combination of Loop Diuretics With Thiazide-Type Diuretics in Heart Failure - p. 189 182. Coenzyme Q10, Rosuvastatin, and Clinical Outcomes in Heart Failure: A Pre-Specified Substudy of CORONA (Controlled Rosuvastatin Multinational Study in Heart Failure) - p. 190 183. Effects of Telmisartan Added to Angiotensin-Converting Enzyme Inhibitors on Mortality and Morbidity in Hemodialysis Patients With Chronic Heart Failure: A Double-Blind, Placebo-Controlled Trial - p. 191 184. Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study - p. 192 185. PDE5 Inhibition With Sildenafil Improves Left Ventricular Diastolic Function, Cardiac Geometry, and Clinical Status in Patients With Stable Systolic Heart Failure: Results of a 1-Year, Prospective, Randomized, Placebo-Controlled Study - p. 193 186. Spironolactone use at discharge was associated with improved survival in hospitalized patients with systolic heart failure - p. 194 187. How often we need to measure brain natriuretic peptide (BNP) blood levels in patients admitted to the hospital for acute severe heart failure? Role of serial measurements to improve short-term prognostic stratification - p. 196 188. N-Terminal Pro–B-Type Natriuretic Peptide–Guided, Intensive Patient Management in Addition to Multidisciplinary Care in Chronic Heart Failure: A 3-Arm, Prospective, Randomized Pilot Study - p. 197 189. Improved Outcomes With Early Collaborative Care of Ambulatory Heart Failure Patients Discharged From the Emergency Department - p. 199 190. Novel strategies in diastolic heart failure - p. 200 191. Concordant Versus Discordant Left Bundle Branch Block in Heart Failure Patients: Novel Clinical Value of an Old Electrocardiographic Diagnosis - p. 201 192. Obesity and survival in patients with heart failure and preserved systolic function: A U-shaped relationship - p. 202 193. Relation of Left Ventricular Ejection Fraction and Functional Capacity With Metabolism and Inflammation in Chronic Heart Failure With Reduced Ejection Fraction (from the MIMICA Study) - p. 203 194. Usefulness of Soluble Endoglin as a Noninvasive Measure of Left Ventricular Filling Pressure in Heart Failure - p. 204 195. Long-Acting Phosphodiesterase-5 Inhibitor Tadalafil Attenuates Doxorubicin-Induced Cardiomyopathy without Interfering with Chemotherapeutic Effect - p. 206 196. Iron Overload Cardiomyopathy: Better Understanding of an Increasing Disorder - p. 208 197. Late benefits of dual-chamber pacing in obstructive hypertrophic cardiomyopathy: a 10-year follow-up study - p. 209 198. Myocardial Scar Visualized by Cardiovascular Magnetic Resonance Imaging Predicts Major Adverse Events in Patients With Hypertrophic Cardiomyopathy - p. 210 199. Risk of heart failure relapse in subsequent pregnancy among peripartum cardiomyopathy mothers - p. 212 200. Aortic Valve Replacement With 17-mm Mechanical Prostheses: Is Patient–Prosthesis Mismatch a Relevant Phenomenon? - p. 213 201. Clinical course and predictors of death in prosthetic valve endocarditis over a 20-year period - p. 214 202. Comparison Between Transcatheter and Surgical Prosthetic Valve Implantation in Patients With Severe Aortic Stenosis and Reduced Left Ventricular Ejection Fraction - p. 215 203. Impact of Baseline Severity of Aortic Valve Stenosis on Effect of Intensive Lipid Lowering Therapy (from the SEAS Study) - p. 216 204. Impact of Early Surgery on Embolic Events in Patients With Infective Endocarditis - p. 217 205. Prognostic Implications of Mitral Regurgitation in Patients With Severe Aortic Regurgitation - p. 218 206. Age-Dependent Profile of Left-Sided Infective Endocarditis: A 3-Center Experience - p. 219 207. Comprehensive Diagnostic Strategy for Blood Culture–Negative Endocarditis: A Prospective Study of 819 New Cases - p. 220 208. Conclusion about the association between valve surgery and mortality in an infective endocarditis cohort changed after adjusting for survivor bias - p. 221 209. Relation of Level of B-Type Natriuretic Peptide With Outcomes in Patients With Infective Endocarditis - p. 222 210. Natural History of Very Severe Aortic Stenosis - p. 223 211. Anti-heart and anti-intercalated disk autoantibodies: evidence for autoimmunity in idiopathic recurrent acute pericarditis - p. 224 212. COlchicine for the Prevention of the Post-pericardiotomy Syndrome (COPPS): a multicentre, randomized, double-blind, placebo-controlled trial - p. 225 213. Atrial septal defects versus ventricular septal defects in BREATHE-5, a placebo-controlled study of pulmonary arterial hypertension related to Eisenmenger’s syndrome: A subgroup analysis - p. 226 214. Dabigatran versus Warfarin in Patients with Atrial Fibrillation - p. 227 215. Comparison of Prognostic Value of Echographic Risk Score With the Thrombolysis In Myocardial Infarction (TIMI) and Global Registry In Acute Coronary Events (GRACE) Risk Scores in Acute Coronary Syndrome - p. 228 216. Combinations of prognostic tools for identification of high-risk normotensive patients with acute symptomatic pulmonary embolism - p. 230 217. Analysis of the Impact of Early Surgery on In-Hospital Mortality of Native Valve Endocarditis: Use of Propensity Score and Instrumental Variable Methods to Adjust for Treatment-Selection Bias - p. 231 218. High prevalence of intramural coronary infection in patients with drug-resistant cardiac syndrome X: comparison with chronic stable angina and normal controls - p. 232 219. Chapter 6: Age as a Risk Factor for Stroke in Atrial Fibrillation Patients: Implications for Thromboprophylaxis - p. 233 220. Association Between Familial Atrial Fibrillation and Risk of New-Onset Atrial Fibrillation - p. 234 221. Effect of Combined Spironolactone–β-Blocker ± Enalapril Treatment on Occurrence of Symptomatic Atrial Fibrillation Episodes in Patients With a History of Paroxysmal Atrial Fibrillation (SPIR-AF Study) - p. 235 222. Efficacy and Safety of Prescription Omega-3 Fatty Acids for the Prevention of Recurrent Symptomatic Atrial Fibrillation: A Randomized Controlled Trial - p. 236 223. Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: an analysis of the RE-LY trial - p. 237 224. Effect of Home Testing of International Normalized Ratio on Clinical Events - p. 238 225. Atrial fibrillation termination as a procedural endpoint during ablation in long-standing persistent atrial fibrillation - p. 239 226. Ablation of long-standing persistent atrial fibrillation with multielectrode ablation catheter - p. 240 227. Efficacy of catheter ablation and surgical CryoMaze procedure in patients with long-lasting persistent atrial fibrillation and rheumatic heart disease: a randomized trial - p. 241 228. Prevention of Atrial Fibrillation Recurrence With Corticosteroids After Radiofrequency Catheter Ablation: A Randomized Controlled Trial - p. 242 229. The CHADS Score Role in Managing Anticoagulation After Surgical Ablation for Atrial Fibrillation - p. 243 230. Radiofrequency Catheter Ablation of Atrial Fibrillation: A Cause of Silent Thromboembolism?: Magnetic Resonance Imaging Assessment of Cerebral Thromboembolism in Patients Undergoing Ablation of Atrial Fibrillation - p. 244 231. Clinical Significance of Early Recurrences of Atrial Tachycardia After Atrial Fibrillation Ablation - p. 245 232. Characteristics of Complex Fractionated Electrograms in Nonpulmonary Vein Ectopy Initiating Atrial Fibrillation/Atrial Tachycardia - p. 246 233. Atrial fibrillation following lung transplantation: double but not single lung transplant is associated with long-term freedom from paroxysmal atrial fibrillation - p. 247 234. Prophylactic ventral cardiac denervation: Does it reduce incidence of atrial fibrillation after coronary artery bypass grafting? - p. 248 235. Gender Differences in the Clinical Characteristics and Atrioventricular Nodal Conduction Properties in Patients with Atrioventricular Nodal Reentrant Tachycardia - p. 249 236. Complication Rates Associated With Pacemaker or Implantable Cardioverter-Defibrillator Generator Replacements and Upgrade Procedures: Results From the REPLACE Registry - p. 250 237. Atrioventricular nodal ablation predicts survival benefit in patients with atrial fibrillation receiving cardiac resynchronization therapy - p. 251 238. Effect of Cardiac Resynchronization Therapy on Reverse Remodeling and Relation to Outcome: Multicenter Automatic Defibrillator Implantation Trial: Cardiac Resynchronization Therapy - p. 252 239. Cardiac Resynchronization Therapy in Asymptomatic or Mildly Symptomatic Heart Failure Patients in Relation to Etiology: Results From the REVERSE (REsynchronization reVErses Remodeling in Systolic Left vEntricular Dysfunction) Study - p. 253 240. Bundle-Branch Block Morphology and Other Predictors of Outcome After Cardiac Resynchronization Therapy in Medicare Patients - p. 254 241. The Value of Defibrillator Electrograms for Recognition of Clinical Ventricular Tachycardias and for Pace Mapping of Post-Infarction Ventricular Tachycardia - p. 255 242. Long-term outcomes and clinical predictors for pacemaker-requiring bradyarrhythmias after cardiac transplantation: Analysis of the UNOS/OPTN cardiac transplant database - p. 256 243. 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