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Chronic Complications of Diabetes Mellitus: Current Outlook and Novel Pathophysiological Insights provides a holistic view of the disease, discussing not only its classical complications but also the under recognized and managed conditions associated with diabetes. Chapters also discuss advances in our understanding of the genomic architecture of diabetes complications and how precision medicine can be used to personalize their management. Endocrinologists, diabetologists, primary care physicians and researchers interested in complications of diabetes mellitus and cutting-edge information will find this to be a comprehensive tome on the topic.

Diabetes complications include pathological changes usually related to the vascular system and classical target organs. However, there are also nonclassical complications independent or partially independent from vascular damage that are often overlooked.

  • Describes pathophysiology, clinical aspects and treatment of complications of diabetes, including nonclassical complications such as diabetic bone disease and diabetic cardiomyopathy
  • Addresses and discusses challenges in the management of diabetes complications, including prevention and therapeutic strategies
  • Presents up-to-date, thoroughly referenced information for clinicians, researchers and other healthcare providers

1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. Contributors - p. ix 7. Chapter 1. Overview on chronic complications of diabetes mellitus - p. 1 8. Chapter 2. Epidemiology of chronic complications of diabetes: A global perspective - p. 11 9. Chapter 3. Molecular mechanisms involved in hyperglycemia-induced cellular damage - p. 25 10. Chapter 4. Vascular calcification in diabetes mellitus: Molecular mechanisms and clinical implications - p. 39 11. Chapter 5. Pathogenesis of diabetic atherosclerotic cardiovascular disease - p. 53 12. Chapter 6. Diabetic retinopathy: New insights - p. 63 13. Chapter 7. Macular edema: A fearful complication of diabetic eye disease - p. 87 14. Chapter 8. Retinal neurodegeneration: Importance in diabetes management - p. 101 15. Chapter 9. Diabetic neuropathy: Current issues in diagnosis and prevention - p. 117 16. Chapter 10. Pathophysiological and clinical aspects of nonclassical targets of microangiopathy - p. 165 17. Chapter 11. Diabetic bone disease: Metabolic and microvascular damage - p. 173 18. Chapter 12. Nonalcoholic fatty liver disease: What comes before and what are the consequences? - p. 185 19. Chapter 13. The diabetic lung - p. 207 20. Chapter 14. Diabetes-related cognitive impairment and dementia - p. 215 21. Chapter 15. Cancer in diabetes: Who is who? - p. 231 22. Chapter 16. Role of glycemic legacy and glycemic variability in the development and progression of complications of diabetes - p. 245 23. Chapter 17. Prevention and management of chronic kidney disease in diabetes - p. 251 24. Chapter 18. Heart failure in diabetes: Current clinical management - p. 263 25. Chapter 19. Diabetic eye disease: novel therapeutic strategies - p. 279 26. Chapter 20. Management of diabetic foot disease - p. 295 27. Index - p. 315

Descripcion
Descripción

Chronic Complications of Diabetes Mellitus: Current Outlook and Novel Pathophysiological Insights provides a holistic view of the disease, discussing not only its classical complications but also the under recognized and managed conditions associated with diabetes. Chapters also discuss advances in our understanding of the genomic architecture of diabetes complications and how precision medicine can be used to personalize their management. Endocrinologists, diabetologists, primary care physicians and researchers interested in complications of diabetes mellitus and cutting-edge information will find this to be a comprehensive tome on the topic.

Diabetes complications include pathological changes usually related to the vascular system and classical target organs. However, there are also nonclassical complications independent or partially independent from vascular damage that are often overlooked.

  • Describes pathophysiology, clinical aspects and treatment of complications of diabetes, including nonclassical complications such as diabetic bone disease and diabetic cardiomyopathy
  • Addresses and discusses challenges in the management of diabetes complications, including prevention and therapeutic strategies
  • Presents up-to-date, thoroughly referenced information for clinicians, researchers and other healthcare providers

1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. Contributors - p. ix 7. Chapter 1. Overview on chronic complications of diabetes mellitus - p. 1 8. Chapter 2. Epidemiology of chronic complications of diabetes: A global perspective - p. 11 9. Chapter 3. Molecular mechanisms involved in hyperglycemia-induced cellular damage - p. 25 10. Chapter 4. Vascular calcification in diabetes mellitus: Molecular mechanisms and clinical implications - p. 39 11. Chapter 5. Pathogenesis of diabetic atherosclerotic cardiovascular disease - p. 53 12. Chapter 6. Diabetic retinopathy: New insights - p. 63 13. Chapter 7. Macular edema: A fearful complication of diabetic eye disease - p. 87 14. Chapter 8. Retinal neurodegeneration: Importance in diabetes management - p. 101 15. Chapter 9. Diabetic neuropathy: Current issues in diagnosis and prevention - p. 117 16. Chapter 10. Pathophysiological and clinical aspects of nonclassical targets of microangiopathy - p. 165 17. Chapter 11. Diabetic bone disease: Metabolic and microvascular damage - p. 173 18. Chapter 12. Nonalcoholic fatty liver disease: What comes before and what are the consequences? - p. 185 19. Chapter 13. The diabetic lung - p. 207 20. Chapter 14. Diabetes-related cognitive impairment and dementia - p. 215 21. Chapter 15. Cancer in diabetes: Who is who? - p. 231 22. Chapter 16. Role of glycemic legacy and glycemic variability in the development and progression of complications of diabetes - p. 245 23. Chapter 17. Prevention and management of chronic kidney disease in diabetes - p. 251 24. Chapter 18. Heart failure in diabetes: Current clinical management - p. 263 25. Chapter 19. Diabetic eye disease: novel therapeutic strategies - p. 279 26. Chapter 20. Management of diabetic foot disease - p. 295 27. Index - p. 315

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