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Dr. Muir and Dr. Rose are key opinion leaders in the area of endocrinology, and they have created a state-of-the-art issue for neonatologists. The clinical reviews will prepare perinatologists and neonatologists for the challenges in clinical endocrinology that arise in fetuses and newborns. More specifically, authors will provide updates on the biological basis of disorders in order to illustrate the rationale for diagnostic approaches and current therapies and to provide readers with a basis to consider and evaluate new clinical offerings. Articles on the following topics are included in the issue: Congenital hypothyroidism; Thyroid function in the NICU; Neonatal thyrotoxicosis; Neonatal diabetes; Hypersinsulinism; Hypopituitarism; Glucocorticoid use in the NICU/ neonatal adrenal function; Adrenal insufficiency, CAH, Prenatal treatment of CAH; Neonatal Cushing Disease/Congenital endocrine tumors; Early ID of Turner Syndrome/Preserving fertility; and Bone mineral/ Calcium disorders in the neonate.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. CME Accreditation Page - p. x 7. Forthcoming Issues - p. xii 8. Foreword - p. xiii 9. Preface - p. xvii 10. Congenital Hypothyroidism - p. 1 11. Thyroid Function in the Neonatal Intensive Care Unit - p. 19 12. Neonatal Thyrotoxicosis - p. 31 13. Neonatal Diabetes Mellitus: An Update on Diagnosis and Management - p. 41 14. Hyperinsulinism in the Neonate - p. 61 15. Congenital Hypopituitarism - p. 75 16. Use of Glucocorticoids for the Fetus and Preterm Infant - p. 93 17. Neonatal Cushing Syndrome: A Rare but Potentially Devastating Disease - p. 103 18. Turner Syndrome: Diagnostic and Management Considerations for Perinatal Clinicians - p. 119 19. Mineral Homeostasis and Effects on Bone Mineralization in the Preterm Neonate - p. 129 20. Appendices A to C - p. 143

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Dr. Muir and Dr. Rose are key opinion leaders in the area of endocrinology, and they have created a state-of-the-art issue for neonatologists. The clinical reviews will prepare perinatologists and neonatologists for the challenges in clinical endocrinology that arise in fetuses and newborns. More specifically, authors will provide updates on the biological basis of disorders in order to illustrate the rationale for diagnostic approaches and current therapies and to provide readers with a basis to consider and evaluate new clinical offerings. Articles on the following topics are included in the issue: Congenital hypothyroidism; Thyroid function in the NICU; Neonatal thyrotoxicosis; Neonatal diabetes; Hypersinsulinism; Hypopituitarism; Glucocorticoid use in the NICU/ neonatal adrenal function; Adrenal insufficiency, CAH, Prenatal treatment of CAH; Neonatal Cushing Disease/Congenital endocrine tumors; Early ID of Turner Syndrome/Preserving fertility; and Bone mineral/ Calcium disorders in the neonate.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. CME Accreditation Page - p. x 7. Forthcoming Issues - p. xii 8. Foreword - p. xiii 9. Preface - p. xvii 10. Congenital Hypothyroidism - p. 1 11. Thyroid Function in the Neonatal Intensive Care Unit - p. 19 12. Neonatal Thyrotoxicosis - p. 31 13. Neonatal Diabetes Mellitus: An Update on Diagnosis and Management - p. 41 14. Hyperinsulinism in the Neonate - p. 61 15. Congenital Hypopituitarism - p. 75 16. Use of Glucocorticoids for the Fetus and Preterm Infant - p. 93 17. Neonatal Cushing Syndrome: A Rare but Potentially Devastating Disease - p. 103 18. Turner Syndrome: Diagnostic and Management Considerations for Perinatal Clinicians - p. 119 19. Mineral Homeostasis and Effects on Bone Mineralization in the Preterm Neonate - p. 129 20. Appendices A to C - p. 143

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