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In collaboration with Consulting Editor, Dr. Norman Gitlin, Dr. Tarek Hassanein has assembled top experts in hepatology to bring current information on the topic of Hepatitis B Virus. The issue provides the most current information on the prevention and care of infected patients. Specific articles are devoted to the following topics: Global perspective on HBV infections in the era of effective vaccines; Understanding the natural history of HBV infection and the new definitions of cure and the endpoints of clinical trials; HBV/HCV coinfection in the era of HCV-DAAs; Antiretroviral effects on HBV/HIV coinfection and the natural history of liver disease; Impact of HBV infection on HCC and liver transplantation; HBV in pregnant women and their infants; WHO guidelines for prevention, care and treatment of individuals infected with HBV: A US perspective; Reconciling the difference between the major HBV treatment guidelines: AASLD, EASL, APASL; HBV/HDV coinfection: A challenge for therapeutics; and The effects of hepatic steatosis on the natural history of HBV infection. Readers will come away with the current information they need to manage patient outcomes.

1. Screening and Prophylaxis to Prevent Hepatitis B Reactivation: Introduction and Immunology - p. 487 2. Screening and Prophylaxis to Prevent Hepatitis B Reactivation: Transplant Recipients - p. 493 3. Screening and Prophylaxis to Prevent Hepatitis B Reactivation: Patients with Hematological and Solid Tumor Malignancies - p. 511 4. Screening and Prophylaxis to Prevent Hepatitis B Reactivation: Other Populations and Newer Agents - p. 521 5. Drugs in the Pipeline for HBV - p. 535 6. HBV/HDV Coinfection: A Challenge for Therapeutics - p. 557

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In collaboration with Consulting Editor, Dr. Norman Gitlin, Dr. Tarek Hassanein has assembled top experts in hepatology to bring current information on the topic of Hepatitis B Virus. The issue provides the most current information on the prevention and care of infected patients. Specific articles are devoted to the following topics: Global perspective on HBV infections in the era of effective vaccines; Understanding the natural history of HBV infection and the new definitions of cure and the endpoints of clinical trials; HBV/HCV coinfection in the era of HCV-DAAs; Antiretroviral effects on HBV/HIV coinfection and the natural history of liver disease; Impact of HBV infection on HCC and liver transplantation; HBV in pregnant women and their infants; WHO guidelines for prevention, care and treatment of individuals infected with HBV: A US perspective; Reconciling the difference between the major HBV treatment guidelines: AASLD, EASL, APASL; HBV/HDV coinfection: A challenge for therapeutics; and The effects of hepatic steatosis on the natural history of HBV infection. Readers will come away with the current information they need to manage patient outcomes.

1. Screening and Prophylaxis to Prevent Hepatitis B Reactivation: Introduction and Immunology - p. 487 2. Screening and Prophylaxis to Prevent Hepatitis B Reactivation: Transplant Recipients - p. 493 3. Screening and Prophylaxis to Prevent Hepatitis B Reactivation: Patients with Hematological and Solid Tumor Malignancies - p. 511 4. Screening and Prophylaxis to Prevent Hepatitis B Reactivation: Other Populations and Newer Agents - p. 521 5. Drugs in the Pipeline for HBV - p. 535 6. HBV/HDV Coinfection: A Challenge for Therapeutics - p. 557

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