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The field of hepatobiliary diseases has advanced enormously in the past 3 decades. The incorporation of new diagnostic and therapeutic interventions in clinical hepatology as well as liver transplantation has exponentially grown and specialty fields have emerged within the liver disease arena. Interventional procedures play a critical role in the management of patients with hepatobiliary diseases as they offer diagnostic and definite treatment options for an array of conditions. Interventions include those that directly measure portal pressure, perform transjugular liver biopsy and place transjugular intrahepatic portsosystemic shunts as therapy for complications of portal hypertension. Other commonly performed intervention is digestive and hepatobiliary endoscopy which offers not only diagnostic but also therapeutic choices in various areas such as portal hypertension and hepatobiliary disease. Endoscopy plays a fundamental role in the management of patients with almost all types of liver disease. Additionally, both the fields of hepatology and endoscopy have become very specialized and thus a thorough knowledge of the indications, findings, therapeutic possibilities and complications that arise from endoscopic interventions is a must for the practicing clinician. The rising incidence of liver cancer has also placed radiofrequency ablation and chemoembolization of liver lesions at the forefront of interventional therapies for hepatocellular carcinoma. Finally the management of acute liver failure has certainly evolved with new therapeutic options such as liver assist devices that can help manage these patients in the intensive care unit. This issue of Clinics in Liver Disease devoted to Interventional Hepatology is a timely and unique one. The Guest Editors have assembled an outstanding group of experts in several fields that can provide practitioners with state of the art and evidence based articles that help manage patients with hepatobiliary disease.

1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Contributors - p. 4 5. Forthcoming Issues - p. 7 6. Preface: Interventional Procedures in Hepatobiliary Diseases - p. 8 7. Transjugular Liver Biopsy - p. 9 8. Measurement of Portal Pressure - p. 15 9. Endoscopic Band Ligation and Esophageal Stents for Acute Variceal Bleeding - p. 23 10. Endoscopic Treatment of Gastric Varices - p. 32 11. Endovascular Management of Gastric Varices - p. 42 12. Transjugular Intrahepatic Portosystemic Shunt - p. 51 13. Transarterial Chemoembolization and Yittrium-90 for Liver Cancer and Other Lesions - p. 64 14. Endoscopic Retrograde Cholangiopancreatography for Cholangiocarcinoma - p. 71 15. Endoscopic Retrograde Cholangiopancreatography for Primary Sclerosing Cholangitis - p. 74 16. Endoscopic Retrograde Cholangiography for Biliary Anastomotic Strictures After Liver Transplantation - p. 82 17. Cholangioscopy in Liver Disease - p. 90 18. Molecular Adsorbent Recirculating System and Bioartificial Devices for Liver Failure - p. 100 19. Intensive Care Unit Management of Patients with Liver Failure - p. 106 20. Index - p. 118

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The field of hepatobiliary diseases has advanced enormously in the past 3 decades. The incorporation of new diagnostic and therapeutic interventions in clinical hepatology as well as liver transplantation has exponentially grown and specialty fields have emerged within the liver disease arena. Interventional procedures play a critical role in the management of patients with hepatobiliary diseases as they offer diagnostic and definite treatment options for an array of conditions. Interventions include those that directly measure portal pressure, perform transjugular liver biopsy and place transjugular intrahepatic portsosystemic shunts as therapy for complications of portal hypertension. Other commonly performed intervention is digestive and hepatobiliary endoscopy which offers not only diagnostic but also therapeutic choices in various areas such as portal hypertension and hepatobiliary disease. Endoscopy plays a fundamental role in the management of patients with almost all types of liver disease. Additionally, both the fields of hepatology and endoscopy have become very specialized and thus a thorough knowledge of the indications, findings, therapeutic possibilities and complications that arise from endoscopic interventions is a must for the practicing clinician. The rising incidence of liver cancer has also placed radiofrequency ablation and chemoembolization of liver lesions at the forefront of interventional therapies for hepatocellular carcinoma. Finally the management of acute liver failure has certainly evolved with new therapeutic options such as liver assist devices that can help manage these patients in the intensive care unit. This issue of Clinics in Liver Disease devoted to Interventional Hepatology is a timely and unique one. The Guest Editors have assembled an outstanding group of experts in several fields that can provide practitioners with state of the art and evidence based articles that help manage patients with hepatobiliary disease.

1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Contributors - p. 4 5. Forthcoming Issues - p. 7 6. Preface: Interventional Procedures in Hepatobiliary Diseases - p. 8 7. Transjugular Liver Biopsy - p. 9 8. Measurement of Portal Pressure - p. 15 9. Endoscopic Band Ligation and Esophageal Stents for Acute Variceal Bleeding - p. 23 10. Endoscopic Treatment of Gastric Varices - p. 32 11. Endovascular Management of Gastric Varices - p. 42 12. Transjugular Intrahepatic Portosystemic Shunt - p. 51 13. Transarterial Chemoembolization and Yittrium-90 for Liver Cancer and Other Lesions - p. 64 14. Endoscopic Retrograde Cholangiopancreatography for Cholangiocarcinoma - p. 71 15. Endoscopic Retrograde Cholangiopancreatography for Primary Sclerosing Cholangitis - p. 74 16. Endoscopic Retrograde Cholangiography for Biliary Anastomotic Strictures After Liver Transplantation - p. 82 17. Cholangioscopy in Liver Disease - p. 90 18. Molecular Adsorbent Recirculating System and Bioartificial Devices for Liver Failure - p. 100 19. Intensive Care Unit Management of Patients with Liver Failure - p. 106 20. Index - p. 118

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