Natural Killer Cells explains the importance of killer cells and how they are produced. It mentions that the most likely explanation for killer cell production is that they serve as a complementary system for T cells as a primary defense against viruses. However, these cells defend against certain viruses only, such as herpes viruses and influenza viruses.
The book also explains the primary functions of killer cells, and it discusses how these cells help recognize damaged tissues, limit further damage to tissues, and regenerate damaged tissues. It discusses how these cells mature and develop, and it covers the different isolation, culture, and propagation methods of these cells. Furthermore, it focuses on the different killer cells that are present in various parts of the human body.
The book concludes by explaining that natural killer cells are utilized for clinical therapy of malignancies, and that they have led to positive outcomes in the field of biology and medicine.
1. Cover image 2. Table of Contents 3. Copyright 4. Contributors 5. Foreword 6. Preface 7. Chapter One. Developmental stages and pathways of NK cell maturation 8. Chapter Two. Developmental origins of thymus-derived natural killer cells 9. Chapter Three. Interferon-producing killer dendritic cells (IKDC) 10. Chapter Four. Natural killer cells in cancer 11. Chapter Five. NK cell immune recognition 12. Chapter Six. NK cell KIR heterogeneity and evolution 13. Chapter Seven. Signalling events in natural killer cells 14. Chapter Eight. Human natural killer cell development 15. Chapter Nine. Isolation, culture and propagation of natural killer cells 16. Chapter Ten. The localization and migration of natural killer cells in health and disease 17. Chapter Eleven. Receptors on NK cells 18. Chapter Twelve. Development and testing of NK cell lines 19. Chapter Thirteen. NK cell-derived cytokines and delivery 20. Chapter Fourteen. NK cells as recipients of cytokine signals 21. Chapter Fifteen. NK cells and chemokines 22. Chapter Sixteen. Natural killer cytolytic activity 23. Chapter Seventeen. Illuminating intranodal natural killer cell behaviour using two-photon microscopy 24. Chapter Eighteen. Dendritic cells and NK cells 25. Chapter Nineteen. NK and NKT cells 26. Chapter Twenty. NK cell and endothelial cell interactions 27. Chapter Twenty-One. Natural killer cell/epithelial interactions 28. Chapter Twenty-Two. NK cell–T cell interactions 29. Chapter Twenty-Three. NK cells and NKT cells in cutaneous disorders 30. Chapter Twenty-Four. Natural killer cells in the respiratory tract 31. Chapter Twenty-Five. Intestinal natural killer cells 32. Chapter Twenty-Six. Natural killer cells in the liver 33. Chapter Twenty-Seven. Natural killer cells in the spleen and lymph node 34. Chapter Twenty-Eight. Nature killer cells in the central nervous system 35. Chapter Twenty-Nine. NK cells in the eye 36. Chapter Thirty. NK cells and reproduction 37. Chapter Thirty-One. Identification of natural killer cells in tissues and their isolation 38. Chapter Thirty-Two. Natural killer cell immune regulation 39. Chapter Thirty-Three. Natural killer cells and transplantation 40. Chapter Thirty-Four. Natural killer cells and autoimmunity 41. Chapter Thirty-Five. Interaction of NK cells with bacteria 42. Chapter Thirty-Six. Natural killer cells and human immunodeficiency virus 43. Chapter Thirty-Seven. Cytomegalovirus infection and NK cells 44. Chapter Thirty-Eight. Natural killer cells in allergy 45. Chapter Thirty-Nine. Natural killer cells in wound healing 46. Chapter Forty. Natural killer cells in atherosclerosis 47. Chapter Forty-One. Natural killer cells in leukaemia 48. Chapter Forty-Two. Natural killer cells and allogeneic haematopoietic cell transplantation 49. Chapter Forty-Three. Clinical trials of NK cells for cancer 50. Chapter Forty-Four. Natural killer cells and hepatitis C virus infection 51. Chapter Forty-Five. Natural killer cells and the biology of parasitism 52. Chapter Forty-Six. Lymphoproliferative disorders of natural killer cells 53. Chapter Forty-Seven. Natural killer cell induction of tolerance 54. Chapter Forty-Eight. Genetic engineering of natural killer cells 55. Chapter Forty-Nine. NK cell-mediated target cell death 56. Chapter Fifty. NK-cell tracking using non-invasive imaging modalities 57. Subject Index
Natural Killer Cells explains the importance of killer cells and how they are produced. It mentions that the most likely explanation for killer cell production is that they serve as a complementary system for T cells as a primary defense against viruses. However, these cells defend against certain viruses only, such as herpes viruses and influenza viruses.
The book also explains the primary functions of killer cells, and it discusses how these cells help recognize damaged tissues, limit further damage to tissues, and regenerate damaged tissues. It discusses how these cells mature and develop, and it covers the different isolation, culture, and propagation methods of these cells. Furthermore, it focuses on the different killer cells that are present in various parts of the human body.
The book concludes by explaining that natural killer cells are utilized for clinical therapy of malignancies, and that they have led to positive outcomes in the field of biology and medicine.
1. Cover image 2. Table of Contents 3. Copyright 4. Contributors 5. Foreword 6. Preface 7. Chapter One. Developmental stages and pathways of NK cell maturation 8. Chapter Two. Developmental origins of thymus-derived natural killer cells 9. Chapter Three. Interferon-producing killer dendritic cells (IKDC) 10. Chapter Four. Natural killer cells in cancer 11. Chapter Five. NK cell immune recognition 12. Chapter Six. NK cell KIR heterogeneity and evolution 13. Chapter Seven. Signalling events in natural killer cells 14. Chapter Eight. Human natural killer cell development 15. Chapter Nine. Isolation, culture and propagation of natural killer cells 16. Chapter Ten. The localization and migration of natural killer cells in health and disease 17. Chapter Eleven. Receptors on NK cells 18. Chapter Twelve. Development and testing of NK cell lines 19. Chapter Thirteen. NK cell-derived cytokines and delivery 20. Chapter Fourteen. NK cells as recipients of cytokine signals 21. Chapter Fifteen. NK cells and chemokines 22. Chapter Sixteen. Natural killer cytolytic activity 23. Chapter Seventeen. Illuminating intranodal natural killer cell behaviour using two-photon microscopy 24. Chapter Eighteen. Dendritic cells and NK cells 25. Chapter Nineteen. NK and NKT cells 26. Chapter Twenty. NK cell and endothelial cell interactions 27. Chapter Twenty-One. Natural killer cell/epithelial interactions 28. Chapter Twenty-Two. NK cell–T cell interactions 29. Chapter Twenty-Three. NK cells and NKT cells in cutaneous disorders 30. Chapter Twenty-Four. Natural killer cells in the respiratory tract 31. Chapter Twenty-Five. Intestinal natural killer cells 32. Chapter Twenty-Six. Natural killer cells in the liver 33. Chapter Twenty-Seven. Natural killer cells in the spleen and lymph node 34. Chapter Twenty-Eight. Nature killer cells in the central nervous system 35. Chapter Twenty-Nine. NK cells in the eye 36. Chapter Thirty. NK cells and reproduction 37. Chapter Thirty-One. Identification of natural killer cells in tissues and their isolation 38. Chapter Thirty-Two. Natural killer cell immune regulation 39. Chapter Thirty-Three. Natural killer cells and transplantation 40. Chapter Thirty-Four. Natural killer cells and autoimmunity 41. Chapter Thirty-Five. Interaction of NK cells with bacteria 42. Chapter Thirty-Six. Natural killer cells and human immunodeficiency virus 43. Chapter Thirty-Seven. Cytomegalovirus infection and NK cells 44. Chapter Thirty-Eight. Natural killer cells in allergy 45. Chapter Thirty-Nine. Natural killer cells in wound healing 46. Chapter Forty. Natural killer cells in atherosclerosis 47. Chapter Forty-One. Natural killer cells in leukaemia 48. Chapter Forty-Two. Natural killer cells and allogeneic haematopoietic cell transplantation 49. Chapter Forty-Three. Clinical trials of NK cells for cancer 50. Chapter Forty-Four. Natural killer cells and hepatitis C virus infection 51. Chapter Forty-Five. Natural killer cells and the biology of parasitism 52. Chapter Forty-Six. Lymphoproliferative disorders of natural killer cells 53. Chapter Forty-Seven. Natural killer cell induction of tolerance 54. Chapter Forty-Eight. Genetic engineering of natural killer cells 55. Chapter Forty-Nine. NK cell-mediated target cell death 56. Chapter Fifty. NK-cell tracking using non-invasive imaging modalities 57. Subject Index