**Selected for Doody’s Core Titles® 2024 in Clinical Genetics**
Prenatal Genetic Counseling: Practical Support for Prenatal Diagnostics, Decision-Making, and Dealing with Uncertainty provides a foundation for new research and a one-stop source for physicians, genetic counselors, psychologists, social workers, general practitioners, grief workers, translational researchers, and administrators seeking to work in the field of clinical genomics ethically and in full consideration of patients’ psychological well-being. Here, an international team of experienced counselors and clinician-scientists lay out the range of methods and technologies applied in prenatal decision-making, including NIPT; invasive testing with microarray analysis or whole genome sequencing; ultrasound screening; and prenatal diagnosis for known hereditary conditions, among others. From here, they examine specific challenges in the clinical translation. In a field where decisions about life or death of a child are made, professionals are bound to encounter uncertainty. This book was co-created by health care practitioners, scientists, patients and students to provide insights and direction for offering support straight from the heart to couples faced with fetal anomalies. To make this possible for all couples, diversity in prenatal genetic counseling is also addressed. Finally, next steps in prenatal genetic counseling research and clinical implementation are discussed. As we are challenged by the rapid advances in prenatal genomics, so are our patients. Learning from our patients with every encounter, this book aims to offer access to the insights we gathered as well as to stimulate lifelong learning.
1. Prenatal Genetic Counseling - p. Page i 2. Cover - p. Page i 3. Title page - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iii 6. Dedication - p. Page v 7. Contents - p. Page vii 8. List of contributors - p. Page viii 9. Preface - p. Page viii 10. List of Illustrations - p. Page x 11. List of Tables - p. Page xi 12. Chapter 1 : A flow from screening to diagnostics - p. Page xi 13. Chapter 2 : From the consulting room: personal narratives of giving prenatal information about fetal anomalies - p. Page 17 14. Chapter 3 : Whole-exome sequencing: A changing landscape of prenatal counseling - p. Page 35 15. Chapter 4 : Dealing with uncertainty in prenatal genomics - p. Page 60 16. Chapter 5 : Addressing diversity in prenatal genetic counseling - p. Page 79 17. Section II : Patient journey and offering support - p. Page 100 18. Chapter 6 : The discovery - p. Page 106 19. Chapter 7 : The iterative process of decision-making - p. Page 119 20. Chapter 8 : Ending the pregnancy - p. Page 135 21. Chapter 9 : Grief - p. Page 162 22. Chapter 10 : Building a life again - p. Page 182 23. Chapter 11 : Organizing support - p. Page 188 24. Chapter 12 : Staying young; student reflections - p. Page 194 25. Appendix : Concluding remarks - p. Page 201 26. Index - p. Page 203
**Selected for Doody’s Core Titles® 2024 in Clinical Genetics**
Prenatal Genetic Counseling: Practical Support for Prenatal Diagnostics, Decision-Making, and Dealing with Uncertainty provides a foundation for new research and a one-stop source for physicians, genetic counselors, psychologists, social workers, general practitioners, grief workers, translational researchers, and administrators seeking to work in the field of clinical genomics ethically and in full consideration of patients’ psychological well-being. Here, an international team of experienced counselors and clinician-scientists lay out the range of methods and technologies applied in prenatal decision-making, including NIPT; invasive testing with microarray analysis or whole genome sequencing; ultrasound screening; and prenatal diagnosis for known hereditary conditions, among others. From here, they examine specific challenges in the clinical translation. In a field where decisions about life or death of a child are made, professionals are bound to encounter uncertainty. This book was co-created by health care practitioners, scientists, patients and students to provide insights and direction for offering support straight from the heart to couples faced with fetal anomalies. To make this possible for all couples, diversity in prenatal genetic counseling is also addressed. Finally, next steps in prenatal genetic counseling research and clinical implementation are discussed. As we are challenged by the rapid advances in prenatal genomics, so are our patients. Learning from our patients with every encounter, this book aims to offer access to the insights we gathered as well as to stimulate lifelong learning.
1. Prenatal Genetic Counseling - p. Page i 2. Cover - p. Page i 3. Title page - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iii 6. Dedication - p. Page v 7. Contents - p. Page vii 8. List of contributors - p. Page viii 9. Preface - p. Page viii 10. List of Illustrations - p. Page x 11. List of Tables - p. Page xi 12. Chapter 1 : A flow from screening to diagnostics - p. Page xi 13. Chapter 2 : From the consulting room: personal narratives of giving prenatal information about fetal anomalies - p. Page 17 14. Chapter 3 : Whole-exome sequencing: A changing landscape of prenatal counseling - p. Page 35 15. Chapter 4 : Dealing with uncertainty in prenatal genomics - p. Page 60 16. Chapter 5 : Addressing diversity in prenatal genetic counseling - p. Page 79 17. Section II : Patient journey and offering support - p. Page 100 18. Chapter 6 : The discovery - p. Page 106 19. Chapter 7 : The iterative process of decision-making - p. Page 119 20. Chapter 8 : Ending the pregnancy - p. Page 135 21. Chapter 9 : Grief - p. Page 162 22. Chapter 10 : Building a life again - p. Page 182 23. Chapter 11 : Organizing support - p. Page 188 24. Chapter 12 : Staying young; student reflections - p. Page 194 25. Appendix : Concluding remarks - p. Page 201 26. Index - p. Page 203
