This issue of Immunology and Allergy Clinics of North America, Guest Edited by Dr. Lisa Kobrynski, is devoted to Primary Immune Deficiencies. Articles in this issue include: Personalized therapy: Immunoglobulin replacement for antibody deficiency; Newborn Screening for Severe Combined Immunodeficiency: Update on newborn screening and lessons learned; Update on Advances in Hematopoietic Cell Transplantation for Primary Immunodeficiency Disorders; Hereditary Autoinflammatory Disorders: Recognition and treatment of inflammatory disorders of the immune system; Use of Immunomodulatory Agents to Treat Primary Immune Deficiencies: Mechanism-based therapy; Secondary Hypogammaglobulinemia: An increasingly recognized complication of treatment with immunomodulators and post-solid organ transplantation; Use of Vaccines in Primary Immunodeficiency; Gastrointestinal Manifestations and Complications of Primary Immunodeficiency Disorders; Hyper IgE Syndromes; Early Onset Inflammatory Bowel Disease; and Genome Testing to Diagnose Primary Immunodeficiency Disorders and to Identify Targeted Therapy.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. viii 7. Foreword - p. ix 8. Preface - p. xi 9. Newborn Screening for Severe Combined Immunodeficiency in the United States: Lessons Learned - p. 1 10. Hereditary Autoinflammatory Disorders: Recognition and Treatment - p. 13 11. Secondary Hypogammaglobulinemia: An Increasingly Recognized Complication of Treatment with Immunomodulators and After Solid Organ Transplantation - p. 31 12. An Update on Syndromes with a Hyper-IgE Phenotype - p. 49 13. Early-Onset Inflammatory Bowel Disease - p. 63 14. Gastrointestinal Manifestations and Complications of Primary Immunodeficiency Disorders - p. 81 15. Personalized Therapy: Immunoglobulin Replacement for Antibody Deficiency - p. 95 16. Update on Advances in Hematopoietic Cell Transplantation for Primary Immunodeficiency Disorders - p. 113 17. Genetic Testing to Diagnose Primary Immunodeficiency Disorders and to Identify Targeted Therapy - p. 129
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This issue of Immunology and Allergy Clinics of North America, Guest Edited by Dr. Lisa Kobrynski, is devoted to Primary Immune Deficiencies. Articles in this issue include: Personalized therapy: Immunoglobulin replacement for antibody deficiency; Newborn Screening for Severe Combined Immunodeficiency: Update on newborn screening and lessons learned; Update on Advances in Hematopoietic Cell Transplantation for Primary Immunodeficiency Disorders; Hereditary Autoinflammatory Disorders: Recognition and treatment of inflammatory disorders of the immune system; Use of Immunomodulatory Agents to Treat Primary Immune Deficiencies: Mechanism-based therapy; Secondary Hypogammaglobulinemia: An increasingly recognized complication of treatment with immunomodulators and post-solid organ transplantation; Use of Vaccines in Primary Immunodeficiency; Gastrointestinal Manifestations and Complications of Primary Immunodeficiency Disorders; Hyper IgE Syndromes; Early Onset Inflammatory Bowel Disease; and Genome Testing to Diagnose Primary Immunodeficiency Disorders and to Identify Targeted Therapy.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. viii 7. Foreword - p. ix 8. Preface - p. xi 9. Newborn Screening for Severe Combined Immunodeficiency in the United States: Lessons Learned - p. 1 10. Hereditary Autoinflammatory Disorders: Recognition and Treatment - p. 13 11. Secondary Hypogammaglobulinemia: An Increasingly Recognized Complication of Treatment with Immunomodulators and After Solid Organ Transplantation - p. 31 12. An Update on Syndromes with a Hyper-IgE Phenotype - p. 49 13. Early-Onset Inflammatory Bowel Disease - p. 63 14. Gastrointestinal Manifestations and Complications of Primary Immunodeficiency Disorders - p. 81 15. Personalized Therapy: Immunoglobulin Replacement for Antibody Deficiency - p. 95 16. Update on Advances in Hematopoietic Cell Transplantation for Primary Immunodeficiency Disorders - p. 113 17. Genetic Testing to Diagnose Primary Immunodeficiency Disorders and to Identify Targeted Therapy - p. 129
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