Radiation Oncology and Radiotherapy Part C, Volume 180 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including Image-guided Radiation Therapy of tumors in preclinical models, Methods to preserve correct dosimetry in small animal irradiators, Monitoring TGFbeta signaling in irradiated tumors, Pipeline to characterize the TCR repertoire of irradiated tumors, Pipeline to identify tumor neoantigens exposed by radiation, Methods to assess abscopal responses in mice, Monitoring the biodistribution of radiolabeled therapeutics in mice, and more. Additional chapters cover Methods to assess radiation-induced fibrosis in mice, Methods to assess radiation-induced cardiotoxicity in mice, Histological assessment of intestinal injury by radiation, Methods to investigate CNS involvement in irradiated mice, Methods to characterize the exosomal output of irradiated cancer cells, and more.
1. Cover image - p. i 2. Table of Contents - p. iii 3. Series Page - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Radiation therapy: An old dog learning new tricks - p. xv 7. Chapter 1: Image-guided radiation therapy of tumors in preclinical models - p. xxv 8. Chapter 2: Pipeline to characterize antigen-specific TCR repertoires in tumors: Examples from an HPV16 tumor model - p. 15 9. Chapter 3: Pipeline to identify neoantigens exposed by radiation - p. 25 10. Chapter 4: Methodologies to evaluate the radiation-induced changes on extracellular vesicles - p. 37 11. Chapter 5: Monitoring TGFβ signaling in irradiated tumors - p. 37 12. Chapter 6: Novel platform for subcutaneous tumor irradiation in mice - p. 37 13. Chapter 7: Methods to assess radiation induced abscopal responses in mice - p. 37 14. Chapter 8: Monitoring the biodistribution of radiolabeled therapeutics in mice - p. 37 15. Chapter 9: Methods to assess radiation-induced fibrosis in mice - p. 37 16. Chapter 10: Methods to assess radiation-induced cardiotoxicity in rodent models - p. 37 17. Chapter 11: Histological assessment of intestinal injury by ionizing radiation - p. 147 18. Chapter 12: A rigorous behavioral testing platform for the assessment of radiation-induced neurological outcomes - p. 175
Radiation Oncology and Radiotherapy Part C, Volume 180 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including Image-guided Radiation Therapy of tumors in preclinical models, Methods to preserve correct dosimetry in small animal irradiators, Monitoring TGFbeta signaling in irradiated tumors, Pipeline to characterize the TCR repertoire of irradiated tumors, Pipeline to identify tumor neoantigens exposed by radiation, Methods to assess abscopal responses in mice, Monitoring the biodistribution of radiolabeled therapeutics in mice, and more. Additional chapters cover Methods to assess radiation-induced fibrosis in mice, Methods to assess radiation-induced cardiotoxicity in mice, Histological assessment of intestinal injury by radiation, Methods to investigate CNS involvement in irradiated mice, Methods to characterize the exosomal output of irradiated cancer cells, and more.
1. Cover image - p. i 2. Table of Contents - p. iii 3. Series Page - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Radiation therapy: An old dog learning new tricks - p. xv 7. Chapter 1: Image-guided radiation therapy of tumors in preclinical models - p. xxv 8. Chapter 2: Pipeline to characterize antigen-specific TCR repertoires in tumors: Examples from an HPV16 tumor model - p. 15 9. Chapter 3: Pipeline to identify neoantigens exposed by radiation - p. 25 10. Chapter 4: Methodologies to evaluate the radiation-induced changes on extracellular vesicles - p. 37 11. Chapter 5: Monitoring TGFβ signaling in irradiated tumors - p. 37 12. Chapter 6: Novel platform for subcutaneous tumor irradiation in mice - p. 37 13. Chapter 7: Methods to assess radiation induced abscopal responses in mice - p. 37 14. Chapter 8: Monitoring the biodistribution of radiolabeled therapeutics in mice - p. 37 15. Chapter 9: Methods to assess radiation-induced fibrosis in mice - p. 37 16. Chapter 10: Methods to assess radiation-induced cardiotoxicity in rodent models - p. 37 17. Chapter 11: Histological assessment of intestinal injury by ionizing radiation - p. 147 18. Chapter 12: A rigorous behavioral testing platform for the assessment of radiation-induced neurological outcomes - p. 175
