Part of the highly regarded Diagnostic Pathology series, Diagnostic Pathology: Blood and Bone Marrow, second edition includes today's most recent knowledge on the latest finds in this subspecialty. New chapters focus on current molecular insights into the pathogenesis of familial disorders and neoplasms, ensuring pathologists, hematopathologists, hematologists, and oncologists alike can deliver the most up-to-date diagnoses possible. Concise, bulleted text coupled with extensive illustrations makes this succinct yet comprehensive reference ideal for clinical use.
1. SECTION 1: INTRODUCTION - p. Cover 2. Chapter 1: Hematopoiesis and Bone Marrow Histology - p. Cover 3. Chapter 2: Bone Marrow Examination and Techniques - p. 13 4. Chapter 3: Synoptic Bone Marrow Reporting - p. 25 5. Chapter 4: Overview of Constitutional and Acquired Bone Marrow Disorders - p. 29 6. SECTION 2: ANEMIA - p. 35 7. Chapter 5: Overview of Anemia - p. 35 8. ACQUIRED ANEMIAS - p. 41 9. Chapter 6: Anemias of Inflammation, Chronic Renal Disease, and Cancer - p. 41 10. Chapter 7: Iron Deficiency Anemia - p. 45 11. Chapter 8: Autoimmune Hemolytic Anemias - p. 49 12. Chapter 9: Alloimmune Hemolytic Anemia and Hemolytic Disease of Newborn - p. 55 13. Chapter 10: Microangiopathic Hemolytic Anemia - p. 59 14. Chapter 11: Megaloblastic Anemia - p. 65 15. Chapter 12: Acquired Nonneoplastic Sideroblastic Anemia - p. 73 16. Chapter 13: Alcoholism-Associated Anemia - p. 77 17. Chapter 14: Anemia in the Elderly - p. 81 18. Chapter 15: Copper Deficiency-Associated Anemia - p. 85 19. Chapter 16: Acquired Red Cell Aplasia - p. 89 20. Chapter 17: Transient Erythroblastopenia of Childhood - p. 93 21. Chapter 18: Parvovirus-Induced Red Cell Aplasia - p. 95 22. Chapter 19: Paroxysmal Nocturnal Hemoglobinuria - p. 99 23. Chapter 20: Acquired Aplastic Anemia - p. 105 24. CONSTITUTIONAL ANEMIAS - p. 109 25. Chapter 21: Thalassemia - p. 109 26. Chapter 22: Sickle Cell Anemia - p. 115 27. Chapter 23: Pyruvate Kinase Deficiency - p. 119 28. Chapter 24: Hereditary Spherocytosis - p. 121 29. Chapter 25: Hereditary Elliptocytosis, Including Hereditary Pyropoikilocytosis - p. 127 30. Chapter 26: Diamond-Blackfan Anemia - p. 131 31. Chapter 27: Fanconi Anemia - p. 135 32. Chapter 28: Congenital Dyserythropoietic Anemia - p. 139 33. Chapter 29: Congenital Sideroblastic Anemia - p. 145 34. Chapter 30: Congenital Megaloblastic Anemia - p. 149 35. SECTION 3: ERYTHROCYTOSIS - p. 155 36. CONSTITUTIONAL - p. 155 37. Chapter 31: Congenital Erythrocytosis - p. 155 38. ACQUIRED - p. 161 39. Chapter 32: Acquired Erythrocytosis - p. 161 40. SECTION 4: BENIGN LEUKOCYTE DISORDERS IN BLOOD AND BONE MARROW - p. 165 41. Chapter 33: Overview of Benign Leukocyte Disorders in Blood and Bone Marrow - p. 165 42. Chapter 34: Pancytopenia - p. 171 43. Chapter 35: Neutropenia - p. 179 44. Chapter 36: Neutrophilia - p. 187 45. Chapter 37: Monocytosis - p. 193 46. Chapter 38: Eosinophilia - p. 199 47. Chapter 39: Basophilia - p. 207 48. Chapter 40: Lymphocytosis - p. 209 49. Chapter 41: Lymphopenia, Constitutional and Acquired - p. 213 50. Chapter 42: Plasmacytosis of Bone Marrow - p. 217 51. Chapter 43: Hematogones in Bone Marrow - p. 225 52. Chapter 44: Lymphoid Aggregates in Bone Marrow - p. 235 53. Chapter 45: Granulomas in Bone Marrow - p. 243 54. SECTION 5: CONSTITUTIONAL GRANULOCYTIC DISORDERS - p. 249 55. CONSTITUTIONAL NEUTROPENIAS - p. 249 56. Chapter 46: Severe Congenital Neutropenia and Cyclic Neutropenia - p. 249 57. Chapter 47: Shwachman-Diamond Syndrome - p. 255 58. Chapter 48: Chediak-Higashi Syndrome - p. 259 59. Chapter 49: Myelokathexis in WHIM Syndrome - p. 263 60. CONSTITUTIONAL NEUTROPHIL ANOMALIES - p. 267 61. Chapter 50: Pelger-Huët Anomaly - p. 267 62. Chapter 51: MYH9-Related Disorders - p. 271 63. Chapter 52: Selected Lysosomal Storage Diseases With Abnormal Leukocyte Granulation - p. 275 64. SECTION 6: MEGAKARYOCYTIC DISORDERS - p. 281 65. Chapter 53: Overview of Megakaryocytic Disorders - p. 281 66. ACQUIRED PLATELET DISORDERS WITH THROMBOCYTOPENIA - p. 293 67. Chapter 54: Immune-Mediated Thrombocytopenia - p. 293 68. Chapter 55: Hemolytic-Uremic Syndrome - p. 299 69. Chapter 56: Thrombotic Thrombocytopenic Purpura - p. 305 70. Chapter 57: Pregnancy-Associated Thrombocytopenia - p. 309 71. CONSTITUTIONAL PLATELET DISORDERS WITH THROMBOCYTOPENIA - p. 313 72. Chapter 58: Thrombocytopenia Absent Radius Syndrome - p. 313 73. Chapter 59: Congenital Amegakaryocytic Thrombocytopenia - p. 317 74. Chapter 60: Gray Platelet Syndrome - p. 321 75. Chapter 61: Wiskott-Aldrich Syndrome-Related Disorders - p. 325 76. Chapter 62: Congenital Thrombotic Thrombocytopenic Purpura - p. 329 77. THROMBOCYTOSIS - p. 333 78. Chapter 63: Thrombocytosis - p. 333 79. SECTION 7: INFECTION - p. 337 80. Chapter 64: Overview of Infection - p. 337 81. Chapter 65: Hantavirus Pulmonary Syndrome - p. 343 82. Chapter 66: Human Immunodeficiency Virus - p. 347 83. Chapter 67: Infectious Mononucleosis Syndromes (Epstein-Barr Virus, Cytomegalovirus) - p. 357 84. Chapter 68: Parvovirus B19 Infection - p. 367 85. Chapter 69: Bacterial Infections, Blood and Bone Marrow Features - p. 371 86. Chapter 70: Fungal Infections, Blood and Bone Marrow Features - p. 381 87. Chapter 71: Helminthic Infections - p. 385 88. Chapter 72: Malaria - p. 389 89. Chapter 73: Other Protozoan Infections - p. 397 90. SECTION 8: MISCELLANEOUS NONNEOPLASTIC DISORDERS AND CONDITIONS - p. 403 91. Chapter 74: Overview and Classification of Hemophagocytic Disorders in Bone Marrow - p. 403 92. Chapter 75: Hematologic Manifestations of Collagen Vascular Disorders - p. 411 93. Chapter 76: Hematologic Manifestations of Chronic Renal Disorders - p. 417 94. Chapter 77: Lysosomal Storage Diseases With Predominantly Histiocytic Storage - p. 419 95. Chapter 78: Other Pregnancy-Associated Hematologic Disorders - p. 425 96. Chapter 79: Gelatinous Transformation and Other Bone Marrow Stromal Disorders - p. 429 97. Chapter 80: Crystals in Bone Marrow - p. 433 98. Chapter 81: Bone Abnormalities in Bone Marrow Specimens - p. 439 99. SECTION 9: MYELOID NEOPLASMS - p. 447 100. Chapter 82: Overview and Classification of Myeloid Neoplasms - p. 447 101. Chapter 83: Clinical Practice Guidelines for Initial Work-Up of Acute Leukemia - p. 455 102. MYELOPROLIFERATIVE NEOPLASMS - p. 457 103. Chapter 84: Overview of Myeloproliferative Neoplasms - p. 457 104. Chapter 85: Chronic Myeloid Leukemia, BCR-ABL1 Positive - p. 461 105. Chapter 86: Chronic Neutrophilic Leukemia - p. 471 106. Chapter 87: Polycythemia Vera - p. 479 107. Chapter 88: Primary Myelofibrosis - p. 485 108. Chapter 89: Essential Thrombocythemia - p. 495 109. Chapter 90: Chronic Eosinophilic Leukemia, Not Otherwise Specified - p. 503 110. Chapter 91: Myeloproliferative Neoplasm, Unclassifiable - p. 511 111. MASTOCYTOSIS - p. 517 112. Chapter 92: Systemic Mastocytosis - p. 517 113. Chapter 93: Mast Cell Leukemia - p. 527 114. MYELOID AND LYMPHOID NEOPLASMS WITH EOSINOPHILIA AND GENE REARRANGEMENTS - p. 535 115. Chapter 94: Myeloid and Lymphoid Neoplasms With PDGFRA Rearrangement - p. 535 116. Chapter 95: Myeloid and Lymphoid Neoplasms With PDGRFB Rearrangement - p. 537 117. Chapter 96: Myeloid and Lymphoid Neoplasms With FGFR1 Rearrangement - p. 539 118. MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASMS - p. 541 119. Chapter 97: Overview of Myelodysplastic/Myeloproliferative Neoplasms - p. 541 120. Chapter 98: Chronic Myelomonocytic Leukemia - p. 545 121. Chapter 99: Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative (aCML) - p. 549 122. Chapter 100: Juvenile Myelomonocytic Leukemia - p. 553 123. Chapter 101: Myelodysplastic/Myeloproliferative Neoplasm With Ring Sideroblasts and Thrombocytosis - p. 557 124. Chapter 102: Myelodysplastic/Myeloproliferative Neoplasms, Unclassifiable - p. 561 125. MYELODYSPLASTIC SYNDROMES - p. 565 126. Chapter 103: Overview and Classification of Myelodysplastic Syndromes - p. 565 127. Chapter 104: Myelodysplastic Syndrome With Single Lineage Dysplasia - p. 575 128. Chapter 105: Myelodysplastic Syndromes With Ring Sideroblasts - p. 579 129. Chapter 106: Myelodysplastic Syndrome With Multilineage Dysplasia - p. 583 130. Chapter 107: Myelodysplastic Syndromes With Excess Blasts - p. 589 131. Chapter 108: Myelodysplastic Syndrome With Isolated del(5q) - p. 595 132. Chapter 109: Myelodysplastic Syndrome, Unclassifiable - p. 603 133. Chapter 110: Childhood Myelodysplastic Syndrome (Refractory Cytopenia of Childhood) - p. 605 134. ACUTE MYELOID LEUKEMIA - p. 611 135. Chapter 111: Overview of Acute Myeloid Leukemia - p. 611 136. Chapter 112: Familial AML/MDS (Germline Predisposition) - p. 621 137. Chapter 113: Acute Myeloid Leukemia With t(8;21)(q22;q22.1), RUNX1-RUNX1T1 - p. 623 138. Chapter 114: Acute Myeloid Leukemia With inv(16)(p13.1q22) or t(16;16)(p13.1;q22), CBFB-MYH11 - p. 633 139. Chapter 115: Acute Promyelocytic Leukemia With PML-RARA - p. 641 140. Chapter 116: Acute Promyelocytic Leukemia With Variant RARA Rearrangement - p. 647 141. Chapter 117: Acute Myeloid Leukemia With t(9;11)(p21.3;q23.3), KMT2A-MLLT3 - p. 649 142. Chapter 118: Subtypes of Acute Myeloid Leukemia: t(6;9), inv(3), t(1;22), t(9;22), Mutated NPM1, Biallelic Mutated CEBPA, Mutated RUNX1 - p. 657 143. Chapter 119: Acute Myeloid Leukemia With Myelodysplasia-Related Changes - p. 661 144. Chapter 120: Therapy-Related Myeloid Neoplasms - p. 667 145. Chapter 121: Acute Myeloid Leukemia With Minimal Differentiation (AML, NOS) - p. 673 146. Chapter 122: Acute Myeloid Leukemia Without Maturation (AML, NOS) - p. 675 147. Chapter 123: Acute Myeloid Leukemia With Maturation (AML, NOS) - p. 677 148. Chapter 124: Acute Myelomonocytic Leukemia (AML, NOS) - p. 679 149. Chapter 125: Acute Monoblastic and Monocytic Leukemia (AML, NOS) - p. 681 150. Chapter 126: Pure Erythroid Leukemia (AML, NOS) - p. 685 151. Chapter 127: Acute Megakaryoblastic Leukemia, Not Otherwise Specified - p. 689 152. Chapter 128: Acute Basophilic Leukemia (AML, NOS) - p. 693 153. Chapter 129: Acute Panmyelosis With Myelofibrosis (AML, NOS) - p. 695 154. Chapter 130: Myeloid Proliferations Related to Down Syndrome - p. 697 155. BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM - p. 701 156. Chapter 131: Blastic Plasmacytoid Dendritic Cell Neoplasm - p. 701 157. SECTION 10: ACUTE LEUKEMIAS OF AMBIGUOUS LINEAGE - p. 709 158. Chapter 132: Acute Undifferentiated Leukemia - p. 709 159. Chapter 133: Mixed Phenotype Acute Leukemia - p. 715 160. LYMPHOID NEOPLASMS - p. 723 161. Chapter 134: Overview of Lymphoid Neoplasms - p. 723 162. B-PRECURSOR NEOPLASMS - p. 731 163. Chapter 135: B-Lymphoblastic Leukemia - p. 731 164. Chapter 136: Novel Genetic Subtypes of B-Lymphoblastic Leukemia - p. 739 165. T-PRECURSOR NEOPLASMS - p. 743 166. Chapter 137: T-Lymphoblastic Leukemia/Lymphoma - p. 743 167. Chapter 138: Early T-Cell Precursor Acute Lymphoblastic Leukemia - p. 749 168. MATURE B-CELL NEOPLASMS - p. 751 169. Chapter 139: Overview and Classification of Mature B-Cell Leukemias, Immunosecretory Lymphomas - p. 751 170. Chapter 140: Monoclonal B-Cell Lymphocytosis - p. 759 171. Chapter 141: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma - p. 761 172. Chapter 142: B-Cell Prolymphocytic Leukemia - p. 771 173. Chapter 143: Splenic Marginal Zone Lymphoma - p. 773 174. Chapter 144: Hairy Cell Leukemia - p. 779 175. Chapter 145: Splenic B-Cell Leukemia, Hairy Cell Leukemia Variant - p. 789 176. Chapter 146: Lymphoplasmacytic Lymphoma - p. 791 177. Chapter 147: Gamma Heavy Chain Disease - p. 797 178. Chapter 148: Monoclonal Gammopathy of Undetermined Significance - p. 801 179. Chapter 149: Plasma Cell Myeloma - p. 805 180. Chapter 150: Burkitt Leukemia/Lymphoma - p. 817 181. Chapter 151: Mantle Cell Lymphoma in Blood and Bone Marrow - p. 823 182. Chapter 152: Follicular Lymphoma in Blood and Bone Marrow - p. 827 183. Chapter 153: Marginal Zone Lymphoma in Blood and Bone Marrow - p. 831 184. Chapter 154: Large B-Cell Lymphomas in Blood and Bone Marrow - p. 833 185. MATURE T-/NK-CELL NEOPLASMS - p. 835 186. Chapter 155: Overview and Classification of Mature T-/NK-Cell Neoplasms in Blood and Bone Marrow - p. 835 187. Chapter 156: T-Cell Prolymphocytic Leukemia - p. 839 188. Chapter 157: T-Cell Large Granular Lymphocytic Leukemia - p. 845 189. Chapter 158: Chronic Lymphoproliferative Disorder of NK Cells - p. 851 190. Chapter 159: Aggressive NK-Cell Leukemia - p. 853 191. Chapter 160: Adult T-Cell Leukemia - p. 857 192. Chapter 161: Mycosis Fungoides/Sézary Syndrome - p. 859 193. Chapter 162: Anaplastic Large Cell Lymphoma in Blood and Bone Marrow - p. 865 194. Chapter 163: Other T-Cell Non-Hodgkin Lymphomas Involving Blood and Bone Marrow - p. 871 195. HODGKIN LYMPHOMA IN BONE MARROW - p. 877 196. Chapter 164: Hodgkin Lymphoma in Bone Marrow, Classic and Lymphocyte-Predominant Subtypes - p. 877 197. SECTION 12: OTHER NEOPLASMS INVOLVING BONE MARROW - p. 883 198. Chapter 165: Langerhans Cell Histiocytosis in Bone Marrow - p. 883 199. Chapter 166: Posttransplant Lymphoproliferative Disorders in Bone Marrow - p. 889 200. Chapter 167: Metastatic Carcinoma and Sarcoma - p. 895 201. INDEX - p. 901
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Part of the highly regarded Diagnostic Pathology series, Diagnostic Pathology: Blood and Bone Marrow, second edition includes today's most recent knowledge on the latest finds in this subspecialty. New chapters focus on current molecular insights into the pathogenesis of familial disorders and neoplasms, ensuring pathologists, hematopathologists, hematologists, and oncologists alike can deliver the most up-to-date diagnoses possible. Concise, bulleted text coupled with extensive illustrations makes this succinct yet comprehensive reference ideal for clinical use.
1. SECTION 1: INTRODUCTION - p. Cover 2. Chapter 1: Hematopoiesis and Bone Marrow Histology - p. Cover 3. Chapter 2: Bone Marrow Examination and Techniques - p. 13 4. Chapter 3: Synoptic Bone Marrow Reporting - p. 25 5. Chapter 4: Overview of Constitutional and Acquired Bone Marrow Disorders - p. 29 6. SECTION 2: ANEMIA - p. 35 7. Chapter 5: Overview of Anemia - p. 35 8. ACQUIRED ANEMIAS - p. 41 9. Chapter 6: Anemias of Inflammation, Chronic Renal Disease, and Cancer - p. 41 10. Chapter 7: Iron Deficiency Anemia - p. 45 11. Chapter 8: Autoimmune Hemolytic Anemias - p. 49 12. Chapter 9: Alloimmune Hemolytic Anemia and Hemolytic Disease of Newborn - p. 55 13. Chapter 10: Microangiopathic Hemolytic Anemia - p. 59 14. Chapter 11: Megaloblastic Anemia - p. 65 15. Chapter 12: Acquired Nonneoplastic Sideroblastic Anemia - p. 73 16. Chapter 13: Alcoholism-Associated Anemia - p. 77 17. Chapter 14: Anemia in the Elderly - p. 81 18. Chapter 15: Copper Deficiency-Associated Anemia - p. 85 19. Chapter 16: Acquired Red Cell Aplasia - p. 89 20. Chapter 17: Transient Erythroblastopenia of Childhood - p. 93 21. Chapter 18: Parvovirus-Induced Red Cell Aplasia - p. 95 22. Chapter 19: Paroxysmal Nocturnal Hemoglobinuria - p. 99 23. Chapter 20: Acquired Aplastic Anemia - p. 105 24. CONSTITUTIONAL ANEMIAS - p. 109 25. Chapter 21: Thalassemia - p. 109 26. Chapter 22: Sickle Cell Anemia - p. 115 27. Chapter 23: Pyruvate Kinase Deficiency - p. 119 28. Chapter 24: Hereditary Spherocytosis - p. 121 29. Chapter 25: Hereditary Elliptocytosis, Including Hereditary Pyropoikilocytosis - p. 127 30. Chapter 26: Diamond-Blackfan Anemia - p. 131 31. Chapter 27: Fanconi Anemia - p. 135 32. Chapter 28: Congenital Dyserythropoietic Anemia - p. 139 33. Chapter 29: Congenital Sideroblastic Anemia - p. 145 34. Chapter 30: Congenital Megaloblastic Anemia - p. 149 35. SECTION 3: ERYTHROCYTOSIS - p. 155 36. CONSTITUTIONAL - p. 155 37. Chapter 31: Congenital Erythrocytosis - p. 155 38. ACQUIRED - p. 161 39. Chapter 32: Acquired Erythrocytosis - p. 161 40. SECTION 4: BENIGN LEUKOCYTE DISORDERS IN BLOOD AND BONE MARROW - p. 165 41. Chapter 33: Overview of Benign Leukocyte Disorders in Blood and Bone Marrow - p. 165 42. Chapter 34: Pancytopenia - p. 171 43. Chapter 35: Neutropenia - p. 179 44. Chapter 36: Neutrophilia - p. 187 45. Chapter 37: Monocytosis - p. 193 46. Chapter 38: Eosinophilia - p. 199 47. Chapter 39: Basophilia - p. 207 48. Chapter 40: Lymphocytosis - p. 209 49. Chapter 41: Lymphopenia, Constitutional and Acquired - p. 213 50. Chapter 42: Plasmacytosis of Bone Marrow - p. 217 51. Chapter 43: Hematogones in Bone Marrow - p. 225 52. Chapter 44: Lymphoid Aggregates in Bone Marrow - p. 235 53. Chapter 45: Granulomas in Bone Marrow - p. 243 54. SECTION 5: CONSTITUTIONAL GRANULOCYTIC DISORDERS - p. 249 55. CONSTITUTIONAL NEUTROPENIAS - p. 249 56. Chapter 46: Severe Congenital Neutropenia and Cyclic Neutropenia - p. 249 57. Chapter 47: Shwachman-Diamond Syndrome - p. 255 58. Chapter 48: Chediak-Higashi Syndrome - p. 259 59. Chapter 49: Myelokathexis in WHIM Syndrome - p. 263 60. CONSTITUTIONAL NEUTROPHIL ANOMALIES - p. 267 61. Chapter 50: Pelger-Huët Anomaly - p. 267 62. Chapter 51: MYH9-Related Disorders - p. 271 63. Chapter 52: Selected Lysosomal Storage Diseases With Abnormal Leukocyte Granulation - p. 275 64. SECTION 6: MEGAKARYOCYTIC DISORDERS - p. 281 65. Chapter 53: Overview of Megakaryocytic Disorders - p. 281 66. ACQUIRED PLATELET DISORDERS WITH THROMBOCYTOPENIA - p. 293 67. Chapter 54: Immune-Mediated Thrombocytopenia - p. 293 68. Chapter 55: Hemolytic-Uremic Syndrome - p. 299 69. Chapter 56: Thrombotic Thrombocytopenic Purpura - p. 305 70. Chapter 57: Pregnancy-Associated Thrombocytopenia - p. 309 71. CONSTITUTIONAL PLATELET DISORDERS WITH THROMBOCYTOPENIA - p. 313 72. Chapter 58: Thrombocytopenia Absent Radius Syndrome - p. 313 73. Chapter 59: Congenital Amegakaryocytic Thrombocytopenia - p. 317 74. Chapter 60: Gray Platelet Syndrome - p. 321 75. Chapter 61: Wiskott-Aldrich Syndrome-Related Disorders - p. 325 76. Chapter 62: Congenital Thrombotic Thrombocytopenic Purpura - p. 329 77. THROMBOCYTOSIS - p. 333 78. Chapter 63: Thrombocytosis - p. 333 79. SECTION 7: INFECTION - p. 337 80. Chapter 64: Overview of Infection - p. 337 81. Chapter 65: Hantavirus Pulmonary Syndrome - p. 343 82. Chapter 66: Human Immunodeficiency Virus - p. 347 83. Chapter 67: Infectious Mononucleosis Syndromes (Epstein-Barr Virus, Cytomegalovirus) - p. 357 84. Chapter 68: Parvovirus B19 Infection - p. 367 85. Chapter 69: Bacterial Infections, Blood and Bone Marrow Features - p. 371 86. Chapter 70: Fungal Infections, Blood and Bone Marrow Features - p. 381 87. Chapter 71: Helminthic Infections - p. 385 88. Chapter 72: Malaria - p. 389 89. Chapter 73: Other Protozoan Infections - p. 397 90. SECTION 8: MISCELLANEOUS NONNEOPLASTIC DISORDERS AND CONDITIONS - p. 403 91. Chapter 74: Overview and Classification of Hemophagocytic Disorders in Bone Marrow - p. 403 92. Chapter 75: Hematologic Manifestations of Collagen Vascular Disorders - p. 411 93. Chapter 76: Hematologic Manifestations of Chronic Renal Disorders - p. 417 94. Chapter 77: Lysosomal Storage Diseases With Predominantly Histiocytic Storage - p. 419 95. Chapter 78: Other Pregnancy-Associated Hematologic Disorders - p. 425 96. Chapter 79: Gelatinous Transformation and Other Bone Marrow Stromal Disorders - p. 429 97. Chapter 80: Crystals in Bone Marrow - p. 433 98. Chapter 81: Bone Abnormalities in Bone Marrow Specimens - p. 439 99. SECTION 9: MYELOID NEOPLASMS - p. 447 100. Chapter 82: Overview and Classification of Myeloid Neoplasms - p. 447 101. Chapter 83: Clinical Practice Guidelines for Initial Work-Up of Acute Leukemia - p. 455 102. MYELOPROLIFERATIVE NEOPLASMS - p. 457 103. Chapter 84: Overview of Myeloproliferative Neoplasms - p. 457 104. Chapter 85: Chronic Myeloid Leukemia, BCR-ABL1 Positive - p. 461 105. Chapter 86: Chronic Neutrophilic Leukemia - p. 471 106. Chapter 87: Polycythemia Vera - p. 479 107. Chapter 88: Primary Myelofibrosis - p. 485 108. Chapter 89: Essential Thrombocythemia - p. 495 109. Chapter 90: Chronic Eosinophilic Leukemia, Not Otherwise Specified - p. 503 110. Chapter 91: Myeloproliferative Neoplasm, Unclassifiable - p. 511 111. MASTOCYTOSIS - p. 517 112. Chapter 92: Systemic Mastocytosis - p. 517 113. Chapter 93: Mast Cell Leukemia - p. 527 114. MYELOID AND LYMPHOID NEOPLASMS WITH EOSINOPHILIA AND GENE REARRANGEMENTS - p. 535 115. Chapter 94: Myeloid and Lymphoid Neoplasms With PDGFRA Rearrangement - p. 535 116. Chapter 95: Myeloid and Lymphoid Neoplasms With PDGRFB Rearrangement - p. 537 117. Chapter 96: Myeloid and Lymphoid Neoplasms With FGFR1 Rearrangement - p. 539 118. MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASMS - p. 541 119. Chapter 97: Overview of Myelodysplastic/Myeloproliferative Neoplasms - p. 541 120. Chapter 98: Chronic Myelomonocytic Leukemia - p. 545 121. Chapter 99: Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative (aCML) - p. 549 122. Chapter 100: Juvenile Myelomonocytic Leukemia - p. 553 123. Chapter 101: Myelodysplastic/Myeloproliferative Neoplasm With Ring Sideroblasts and Thrombocytosis - p. 557 124. Chapter 102: Myelodysplastic/Myeloproliferative Neoplasms, Unclassifiable - p. 561 125. MYELODYSPLASTIC SYNDROMES - p. 565 126. Chapter 103: Overview and Classification of Myelodysplastic Syndromes - p. 565 127. Chapter 104: Myelodysplastic Syndrome With Single Lineage Dysplasia - p. 575 128. Chapter 105: Myelodysplastic Syndromes With Ring Sideroblasts - p. 579 129. Chapter 106: Myelodysplastic Syndrome With Multilineage Dysplasia - p. 583 130. Chapter 107: Myelodysplastic Syndromes With Excess Blasts - p. 589 131. Chapter 108: Myelodysplastic Syndrome With Isolated del(5q) - p. 595 132. Chapter 109: Myelodysplastic Syndrome, Unclassifiable - p. 603 133. Chapter 110: Childhood Myelodysplastic Syndrome (Refractory Cytopenia of Childhood) - p. 605 134. ACUTE MYELOID LEUKEMIA - p. 611 135. Chapter 111: Overview of Acute Myeloid Leukemia - p. 611 136. Chapter 112: Familial AML/MDS (Germline Predisposition) - p. 621 137. Chapter 113: Acute Myeloid Leukemia With t(8;21)(q22;q22.1), RUNX1-RUNX1T1 - p. 623 138. Chapter 114: Acute Myeloid Leukemia With inv(16)(p13.1q22) or t(16;16)(p13.1;q22), CBFB-MYH11 - p. 633 139. Chapter 115: Acute Promyelocytic Leukemia With PML-RARA - p. 641 140. Chapter 116: Acute Promyelocytic Leukemia With Variant RARA Rearrangement - p. 647 141. Chapter 117: Acute Myeloid Leukemia With t(9;11)(p21.3;q23.3), KMT2A-MLLT3 - p. 649 142. Chapter 118: Subtypes of Acute Myeloid Leukemia: t(6;9), inv(3), t(1;22), t(9;22), Mutated NPM1, Biallelic Mutated CEBPA, Mutated RUNX1 - p. 657 143. Chapter 119: Acute Myeloid Leukemia With Myelodysplasia-Related Changes - p. 661 144. Chapter 120: Therapy-Related Myeloid Neoplasms - p. 667 145. Chapter 121: Acute Myeloid Leukemia With Minimal Differentiation (AML, NOS) - p. 673 146. Chapter 122: Acute Myeloid Leukemia Without Maturation (AML, NOS) - p. 675 147. Chapter 123: Acute Myeloid Leukemia With Maturation (AML, NOS) - p. 677 148. Chapter 124: Acute Myelomonocytic Leukemia (AML, NOS) - p. 679 149. Chapter 125: Acute Monoblastic and Monocytic Leukemia (AML, NOS) - p. 681 150. Chapter 126: Pure Erythroid Leukemia (AML, NOS) - p. 685 151. Chapter 127: Acute Megakaryoblastic Leukemia, Not Otherwise Specified - p. 689 152. Chapter 128: Acute Basophilic Leukemia (AML, NOS) - p. 693 153. Chapter 129: Acute Panmyelosis With Myelofibrosis (AML, NOS) - p. 695 154. Chapter 130: Myeloid Proliferations Related to Down Syndrome - p. 697 155. BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM - p. 701 156. Chapter 131: Blastic Plasmacytoid Dendritic Cell Neoplasm - p. 701 157. SECTION 10: ACUTE LEUKEMIAS OF AMBIGUOUS LINEAGE - p. 709 158. Chapter 132: Acute Undifferentiated Leukemia - p. 709 159. Chapter 133: Mixed Phenotype Acute Leukemia - p. 715 160. LYMPHOID NEOPLASMS - p. 723 161. Chapter 134: Overview of Lymphoid Neoplasms - p. 723 162. B-PRECURSOR NEOPLASMS - p. 731 163. Chapter 135: B-Lymphoblastic Leukemia - p. 731 164. Chapter 136: Novel Genetic Subtypes of B-Lymphoblastic Leukemia - p. 739 165. T-PRECURSOR NEOPLASMS - p. 743 166. Chapter 137: T-Lymphoblastic Leukemia/Lymphoma - p. 743 167. Chapter 138: Early T-Cell Precursor Acute Lymphoblastic Leukemia - p. 749 168. MATURE B-CELL NEOPLASMS - p. 751 169. Chapter 139: Overview and Classification of Mature B-Cell Leukemias, Immunosecretory Lymphomas - p. 751 170. Chapter 140: Monoclonal B-Cell Lymphocytosis - p. 759 171. Chapter 141: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma - p. 761 172. Chapter 142: B-Cell Prolymphocytic Leukemia - p. 771 173. Chapter 143: Splenic Marginal Zone Lymphoma - p. 773 174. Chapter 144: Hairy Cell Leukemia - p. 779 175. Chapter 145: Splenic B-Cell Leukemia, Hairy Cell Leukemia Variant - p. 789 176. Chapter 146: Lymphoplasmacytic Lymphoma - p. 791 177. Chapter 147: Gamma Heavy Chain Disease - p. 797 178. Chapter 148: Monoclonal Gammopathy of Undetermined Significance - p. 801 179. Chapter 149: Plasma Cell Myeloma - p. 805 180. Chapter 150: Burkitt Leukemia/Lymphoma - p. 817 181. Chapter 151: Mantle Cell Lymphoma in Blood and Bone Marrow - p. 823 182. Chapter 152: Follicular Lymphoma in Blood and Bone Marrow - p. 827 183. Chapter 153: Marginal Zone Lymphoma in Blood and Bone Marrow - p. 831 184. Chapter 154: Large B-Cell Lymphomas in Blood and Bone Marrow - p. 833 185. MATURE T-/NK-CELL NEOPLASMS - p. 835 186. Chapter 155: Overview and Classification of Mature T-/NK-Cell Neoplasms in Blood and Bone Marrow - p. 835 187. Chapter 156: T-Cell Prolymphocytic Leukemia - p. 839 188. Chapter 157: T-Cell Large Granular Lymphocytic Leukemia - p. 845 189. Chapter 158: Chronic Lymphoproliferative Disorder of NK Cells - p. 851 190. Chapter 159: Aggressive NK-Cell Leukemia - p. 853 191. Chapter 160: Adult T-Cell Leukemia - p. 857 192. Chapter 161: Mycosis Fungoides/Sézary Syndrome - p. 859 193. Chapter 162: Anaplastic Large Cell Lymphoma in Blood and Bone Marrow - p. 865 194. Chapter 163: Other T-Cell Non-Hodgkin Lymphomas Involving Blood and Bone Marrow - p. 871 195. HODGKIN LYMPHOMA IN BONE MARROW - p. 877 196. Chapter 164: Hodgkin Lymphoma in Bone Marrow, Classic and Lymphocyte-Predominant Subtypes - p. 877 197. SECTION 12: OTHER NEOPLASMS INVOLVING BONE MARROW - p. 883 198. Chapter 165: Langerhans Cell Histiocytosis in Bone Marrow - p. 883 199. Chapter 166: Posttransplant Lymphoproliferative Disorders in Bone Marrow - p. 889 200. Chapter 167: Metastatic Carcinoma and Sarcoma - p. 895 201. INDEX - p. 901
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