Investigative and Predictive DNA Testing delves into the cutting-edge of DNA analysis, presenting a comprehensive guide that unlocks the potential of DNA in solving complex cases. This book stands as a vital resource for students, practitioners, and researchers in fields such as biology, zoology, medicine, anthropology, microbiology, and genetics. Designed for those with a basic understanding of biological sciences, it is particularly beneficial for graduate, post-graduate, and research level students. The book explores the evolution of DNA analysis, focusing on predictive methods and investigative leads such as ancestry, lineage, and phenotype.
Each chapter, contributed by internationally renowned experts, highlights the transformative role of artificial intelligence and machine learning in enhancing the accuracy and utility of DNA analysis. The book is comprised of various sections, starting with fundamental concepts of investigative and predictive DNA analysis, followed by technological advancements in the field, and concluding with the challenges and future concerns of DNA analysis. It serves as an indispensable tool for anyone looking to expand their knowledge and skills in DNA analysis, making it a must-read for the scientific community.
Describes the fundamentals of investigative and predictive approaches for forensic applications
Explains the technological advances in forensic DNA analysis
Includes real case studies related to predictive DNA analysis
Provides futuristic use and applications of predictive forensic DNA analysis
Uses real time images for easy understanding
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. xvii 7. Preface - p. xxi 8. Part I Module I: Conventional forensic DNA analysis - p. xxii 9. Chapter 1. Fundamentals and principles of forensic DNA analysis - p. 3 10. Chapter 2. Autosomal short tandem repeat analysis and its usefulness in forensic DNA analysis - p. 19 11. Chapter 3. Detection and identification of forensically relevant body fluids - p. 35 12. Chapter 4. Analysis of mitochondrial DNA and its aid in forensic investigation - p. 49 13. Chapter 5. Law and practice of forensic DNA profiling in India: Perspectives and challenges - p. 73 14. Part II Module II: Technological advancements in forensic DNA analysis - p. 94 15. Chapter 6. Understanding Rapid DNA and its application - p. 97 16. Chapter 7. Rapidly mutating Y-short tandem repeats in forensic DNA analysis - p. 107 17. Chapter 8. The use of biallelic genetic markers in forensic DNA analysis - p. 133 18. Chapter 9. Epigenetics and its application in forensic analysis - p. 147 19. Chapter 10. Microbial DNA in forensic science: a tool for predicting postmortem interval - p. 155 20. Chapter 11. Probabilistic genotyping techniques and their applications - p. 165 21. Chapter 12. Applications of genetics in archaeological investigations: exploring human migration and genetic evolution in Indian subcontinent - p. 173 22. Chapter 13. Digital polymerase chain reaction: a revolution in forensic DNA analysis - p. 189 23. Chapter 14. Role of nanotechnology in forensic DNA analysis - p. 201 24. Chapter 15. Advancements in wildlife forensics - p. 221 25. Chapter 16. Usefulness of microsatellite markers in forensic botany - p. 241 26. Chapter 17. DNA barcoding as a useful tool in the identification of endangered plants - p. 255 27. Chapter 18. Prenatal paternity testing and forensic applications of noninvasive prenatal paternity testing technology - p. 277 28. Chapter 19. Secondary transfer and its involvement in forensic investigation - p. 289 29. Part III Module III: Predictive forensic DNA analysis - p. 298 30. Chapter 20. Molecular autopsy for analysis of sudden unexplained death cases - p. 303 31. Chapter 21. Artificial intelligence and machine learning in forensic DNA analysis - p. 315 32. Prediction of Y-chromosome lineages from Y-SNPs and Y-STRs for generating investigative leads - p. 325 33. Chapter 23. Prediction of externally visible characteristics and its role in forensic investigation - p. 349 34. Chapter 24. The advent of investigative genetic genealogy - p. 361 35. Chapter 25. Application of next-generation sequencing techniques in generating investigation leads - p. 375 36. Part IV Module IV: challenges and concerns in forensic DNA analysis - p. 383 37. Chapter 26. Quality assurance and quality control in forensic science: from evidence collection to laboratory analysis - p. 391 38. Chapter 27. Ethical issues in forensic DNA analysis - p. 407 39. Chapter 28. DNA profiling and databases in criminal investigations: privacy-related issues and challenges - p. 425 40. Chapter 29. Challenges in interpretation of compromised cases by DNA profiling - p. 439 41. Chapter 30. Challenges of DNA fingerprinting in mass disaster victim investigations - p. 453 42. Chapter 31. Forensic implications of polymerase chain reaction inhibitors - p. 467 43. Chapter 32. Assessment of the reliability and reproducibility of forensic DNA profiling results - p. 485 44. Chapter 33. Applications of digital polymerase chain reaction in environment and forensic chemistry - p. 495 45. Index - p. 511
Investigative and Predictive DNA Testing delves into the cutting-edge of DNA analysis, presenting a comprehensive guide that unlocks the potential of DNA in solving complex cases. This book stands as a vital resource for students, practitioners, and researchers in fields such as biology, zoology, medicine, anthropology, microbiology, and genetics. Designed for those with a basic understanding of biological sciences, it is particularly beneficial for graduate, post-graduate, and research level students. The book explores the evolution of DNA analysis, focusing on predictive methods and investigative leads such as ancestry, lineage, and phenotype.
Each chapter, contributed by internationally renowned experts, highlights the transformative role of artificial intelligence and machine learning in enhancing the accuracy and utility of DNA analysis. The book is comprised of various sections, starting with fundamental concepts of investigative and predictive DNA analysis, followed by technological advancements in the field, and concluding with the challenges and future concerns of DNA analysis. It serves as an indispensable tool for anyone looking to expand their knowledge and skills in DNA analysis, making it a must-read for the scientific community.
Describes the fundamentals of investigative and predictive approaches for forensic applications
Explains the technological advances in forensic DNA analysis
Includes real case studies related to predictive DNA analysis
Provides futuristic use and applications of predictive forensic DNA analysis
Uses real time images for easy understanding
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. xvii 7. Preface - p. xxi 8. Part I Module I: Conventional forensic DNA analysis - p. xxii 9. Chapter 1. Fundamentals and principles of forensic DNA analysis - p. 3 10. Chapter 2. Autosomal short tandem repeat analysis and its usefulness in forensic DNA analysis - p. 19 11. Chapter 3. Detection and identification of forensically relevant body fluids - p. 35 12. Chapter 4. Analysis of mitochondrial DNA and its aid in forensic investigation - p. 49 13. Chapter 5. Law and practice of forensic DNA profiling in India: Perspectives and challenges - p. 73 14. Part II Module II: Technological advancements in forensic DNA analysis - p. 94 15. Chapter 6. Understanding Rapid DNA and its application - p. 97 16. Chapter 7. Rapidly mutating Y-short tandem repeats in forensic DNA analysis - p. 107 17. Chapter 8. The use of biallelic genetic markers in forensic DNA analysis - p. 133 18. Chapter 9. Epigenetics and its application in forensic analysis - p. 147 19. Chapter 10. Microbial DNA in forensic science: a tool for predicting postmortem interval - p. 155 20. Chapter 11. Probabilistic genotyping techniques and their applications - p. 165 21. Chapter 12. Applications of genetics in archaeological investigations: exploring human migration and genetic evolution in Indian subcontinent - p. 173 22. Chapter 13. Digital polymerase chain reaction: a revolution in forensic DNA analysis - p. 189 23. Chapter 14. Role of nanotechnology in forensic DNA analysis - p. 201 24. Chapter 15. Advancements in wildlife forensics - p. 221 25. Chapter 16. Usefulness of microsatellite markers in forensic botany - p. 241 26. Chapter 17. DNA barcoding as a useful tool in the identification of endangered plants - p. 255 27. Chapter 18. Prenatal paternity testing and forensic applications of noninvasive prenatal paternity testing technology - p. 277 28. Chapter 19. Secondary transfer and its involvement in forensic investigation - p. 289 29. Part III Module III: Predictive forensic DNA analysis - p. 298 30. Chapter 20. Molecular autopsy for analysis of sudden unexplained death cases - p. 303 31. Chapter 21. Artificial intelligence and machine learning in forensic DNA analysis - p. 315 32. Prediction of Y-chromosome lineages from Y-SNPs and Y-STRs for generating investigative leads - p. 325 33. Chapter 23. Prediction of externally visible characteristics and its role in forensic investigation - p. 349 34. Chapter 24. The advent of investigative genetic genealogy - p. 361 35. Chapter 25. Application of next-generation sequencing techniques in generating investigation leads - p. 375 36. Part IV Module IV: challenges and concerns in forensic DNA analysis - p. 383 37. Chapter 26. Quality assurance and quality control in forensic science: from evidence collection to laboratory analysis - p. 391 38. Chapter 27. Ethical issues in forensic DNA analysis - p. 407 39. Chapter 28. DNA profiling and databases in criminal investigations: privacy-related issues and challenges - p. 425 40. Chapter 29. Challenges in interpretation of compromised cases by DNA profiling - p. 439 41. Chapter 30. Challenges of DNA fingerprinting in mass disaster victim investigations - p. 453 42. Chapter 31. Forensic implications of polymerase chain reaction inhibitors - p. 467 43. Chapter 32. Assessment of the reliability and reproducibility of forensic DNA profiling results - p. 485 44. Chapter 33. Applications of digital polymerase chain reaction in environment and forensic chemistry - p. 495 45. Index - p. 511
