This issue of Neurosurgery Clinics, guest edited by Drs. Guy McKhann and Hugues Duffau, with consulting editors Russell R. Lonser and Daniel K. Resnick, will focus on Low-Grade Glioma. Topics includes, but are not limited to, Epidemiology and Molecular Epidemiology; WHO Pathological and Molecular Classification; Molecular Pathogenesis; Glioma Cell Migration and Heterogeneity; Clinical Presentation, Natural History, and Prognosis; LGG Epilepsy; MRI, fMRI, DTI, Molecular Imaging; Brain Mapping Techniques in LGG; Surgical Adjuncts to Increase EOR iMRI, Flourescence, Raman Histology; Mapping Cognition and Emotion; Extent of Resection; EOR vs Molecular Classification; Chemotherapy Treatment and Trials; Radiotherapy Treatment and Trials; Higher Order Surgical Questions; and Building a Glioma Practice.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xi 7. Preface - p. xiii 8. Epidemiology, Pathophysiology, and Classification - p. xiv 9. Epidemiology and Molecular Epidemiology - p. 1 10. Molecular Pathogenesis of Low-Grade Glioma - p. 17 11. Alterations in the Brain Microenvironment in Diffusely Infiltrating Low-Grade Glioma - p. 27 12. Clinical and Imaging - p. 34 13. Clinical Presentation, Natural History, and Prognosis of Diffuse Low-Grade Gliomas - p. 35 14. Diffuse Low-Grade Glioma-Related Epilepsy - p. 43 15. Treatment - p. 54 16. Mapping in Low-Grade Glioma Surgery: Low- and High-Frequency Stimulation - p. 55 17. Surgical Adjuncts to Increase the Extent of Resection: Intraoperative MRI, Fluorescence, and Raman Histology - p. 65 18. Beyond Language: Mapping Cognition and Emotion - p. 75 19. Evidence for Improving Outcome Through Extent of Resection - p. 85 20. Extent of Resection Versus Molecular Classification: What Matters When? - p. 95 21. Chemotherapy Treatment and Trials in Low-Grade Gliomas - p. 103 22. Low-Grade Glioma Radiotherapy Treatment and Trials - p. 111 23. Higher-Order Surgical Questions for Diffuse Low-Grade Gliomas: Supramaximal Resection, Neuroplasticity, and Screening - p. 119 24. How to Build a Neurosurgical Oncology Practice Specializing in Gliomas - p. 129
This issue of Neurosurgery Clinics, guest edited by Drs. Guy McKhann and Hugues Duffau, with consulting editors Russell R. Lonser and Daniel K. Resnick, will focus on Low-Grade Glioma. Topics includes, but are not limited to, Epidemiology and Molecular Epidemiology; WHO Pathological and Molecular Classification; Molecular Pathogenesis; Glioma Cell Migration and Heterogeneity; Clinical Presentation, Natural History, and Prognosis; LGG Epilepsy; MRI, fMRI, DTI, Molecular Imaging; Brain Mapping Techniques in LGG; Surgical Adjuncts to Increase EOR iMRI, Flourescence, Raman Histology; Mapping Cognition and Emotion; Extent of Resection; EOR vs Molecular Classification; Chemotherapy Treatment and Trials; Radiotherapy Treatment and Trials; Higher Order Surgical Questions; and Building a Glioma Practice.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xi 7. Preface - p. xiii 8. Epidemiology, Pathophysiology, and Classification - p. xiv 9. Epidemiology and Molecular Epidemiology - p. 1 10. Molecular Pathogenesis of Low-Grade Glioma - p. 17 11. Alterations in the Brain Microenvironment in Diffusely Infiltrating Low-Grade Glioma - p. 27 12. Clinical and Imaging - p. 34 13. Clinical Presentation, Natural History, and Prognosis of Diffuse Low-Grade Gliomas - p. 35 14. Diffuse Low-Grade Glioma-Related Epilepsy - p. 43 15. Treatment - p. 54 16. Mapping in Low-Grade Glioma Surgery: Low- and High-Frequency Stimulation - p. 55 17. Surgical Adjuncts to Increase the Extent of Resection: Intraoperative MRI, Fluorescence, and Raman Histology - p. 65 18. Beyond Language: Mapping Cognition and Emotion - p. 75 19. Evidence for Improving Outcome Through Extent of Resection - p. 85 20. Extent of Resection Versus Molecular Classification: What Matters When? - p. 95 21. Chemotherapy Treatment and Trials in Low-Grade Gliomas - p. 103 22. Low-Grade Glioma Radiotherapy Treatment and Trials - p. 111 23. Higher-Order Surgical Questions for Diffuse Low-Grade Gliomas: Supramaximal Resection, Neuroplasticity, and Screening - p. 119 24. How to Build a Neurosurgical Oncology Practice Specializing in Gliomas - p. 129
