Developed by 149 experts in the field, The International Consensus Classification of Myeloid and Lymphoid Neoplasms provides key information for use at the microscope to assist in arriving at a swift and accurate diagnosis. Drs. Daniel Arber, Michael J. Borowitz, James Cook, Laurence de Leval, John Goodlad, Robert Hasserjian, Rebecca L. King, Hans-Michael Kvasnicka, and Attilio Orazi lead a team of authors who focus on diagnostic criteria and the clinical significance of each disease entity.
1. Introduction to the International Consensus Classification of Myeloid Disorders and Acute Leukemias - p. 1 2. SECTION 1 Myeloproliferative Neoplasms - p. 21 3. 1 Chronic Myeloid Leukemia - p. 22 4. 2 BCR::ABL1-Negative Myeloproliferative Neoplasms - p. 31 5. 3 Chronic Neutrophilic Leukemia - p. 52 6. 4 Chronic Eosinophilic Leukemia, Not Otherwise Specified - p. 56 7. 5 Myeloproliferative Neoplasms, Unclassifiable - p. 61 8. SECTION 2 Myeloid/Lymphoid Neoplasms With Eosinophilia and Tyrosine Kinase Gene Fusions - p. 67 9. 6 Myeloid/Lymphoid Neoplasms With Eosinophilia and Tyrosine Kinase Gene Fusions - p. 68 10. SECTION 3 Mastocytosis - p. 83 11. 7 Mastocytosis - p. 84 12. SECTION 4 Myelodysplastic/Myeloproliferative Neoplasms - p. 101 13. 8 Chronic Myelomonocytic Leukemia - p. 102 14. 9 Atypical Chronic Myeloid Leukemia - p. 110 15. 10 Myelodysplastic/Myeloproliferative Neoplasm With SF3B1 Mutation and Thrombocytosis - p. 114 16. 11 Myelodysplastic/Myeloproliferative Neoplasm, Not Otherwise Specified - p. 118 17. SECTION 5 Premalignant Clonal Cytopenias and Myelodysplastic Syndromes - p. 123 18. Introduction to Premalignant Clonal Cytopenias and Myelodysplastic Syndromes - p. 124 19. 12 Clonal Cytopenia of Undetermined Significance and Other Clonal Cytopenias - p. 127 20. 13 Myelodysplastic Syndrome With Mutated SF3B1 - p. 132 21. 14 Myelodysplastic Syndrome With del(5q) - p. 136 22. 15 Myelodysplastic Syndrome With Mutated TP53 - p. 140 23. 16 Myelodysplastic Syndrome, Not Otherwise Specified - p. 145 24. 17 Myelodysplastic Syndrome With Excess Blasts - p. 150 25. 18 Myelodysplastic Syndrome/Acute Myeloid Leukemia - p. 153 26. SECTION 6 Pediatric and/or Germline Disorders - p. 159 27. 19 Juvenile Myelomonocytic Leukemia - p. 160 28. 20 Refractory Cytopenia of Childhood and Pediatric Myelodysplastic Syndromes - p. 166 29. 21 Hematologic Malignancies With Germline Predisposition - p. 171 30. SECTION 7 Acute Myeloid Leukemias - p. 189 31. 22 Acute Promyelocytic Leukemia With t(15;17)(q24.1;q21.2)/PML::RARA and Acute Promyelocytic Leukemia With Other RARA Rearrangements - p. 190 32. 23 Acute Myeloid Leukemia With t(8;21)(q22;q22.1/RUNX1::RUNX1T1 - p. 194 33. 24 Acute Myeloid Leukemia With inv(16)(p13.1q22) or t(16;16)(p13.1;q22)/CBFB::MYH11 - p. 198 34. 25 Acute Myeloid Leukemia With t(9;11)(p21.3;q23.3)/KMT2A::MLLT3 and Other KMT2A Rearrangements - p. 202 35. 26 Acute Myeloid Leukemia With t(6;9)(p22.3;q34.1)/DEK::NUP214 - p. 208 36. 27 Acute Myeloid Leukemia With inv(3)(q21.3q26.2) or t(3;3)(q21.3;q26.2)/GATA2; MECOM(EVI1) and Acute Myeloid Leukemia With Other MECOM Rearrangements - p. 211 37. 28 Acute Myeloid Leukemia With Other Rare Recurring Translocations - p. 215 38. 29 Acute Myeloid Leukemia With t(9;22)(q34.1;q11.2)/BCR::ABL1 - p. 218 39. 30 Acute Myeloid Leukemia With Mutated NPM1 - p. 221 40. 31 Acute Myeloid Leukemia With In-Frame bZIP CEBPA Mutations - p. 224 41. 32 Acute Myeloid Leukemia and Myelodysplastic Syndrome/Acute Myeloid Leukemia With Mutated TP53 - p. 228 42. 33 Acute Myeloid Leukemia and Myelodysplastic Syndrome/Acute Myeloid Leukemia With Myelodysplasia-Related Gene Mutations - p. 231 43. 34 Acute Myeloid Leukemia and Myelodysplastic Syndrome/Acute Myeloid Leukemia With Myelodysplasia-Related Cytogenetic Abnormalities - p. 234 44. 35 Acute Myeloid Leukemia and Myelodysplastic Syndrome/Acute Myeloid Leukemia, Not Otherwise Specified - p. 237 45. 36 Myeloid Sarcoma - p. 245 46. SECTION 8 Myeloid Proliferations Associated With Down Syndrome - p. 249 47. 37 Myeloid Proliferations Associated With Down Syndrome - p. 250 48. SECTION 9 Blastic Plasmacytoid Dendritic Cell Neoplasm - p. 255 49. 38 Blastic Plasmacytoid Dendritic Cell Neoplasm - p. 256 50. SECTION 10 Lymphoblastic Neoplasms - p. 261 51. Introduction to Lymphoblastic Neoplasms - p. 262 52. 39 Acute Leukemias of Ambiguous Lineage - p. 275 53. 40 B-Lymphoblastic Leukemias/Lymphomas - p. 289 54. 41 T-Lymphoblastic Leukemias/Lymphomas - p. 315 55. 42 NK-Cell Acute Lymphoblastic Leukemia - p. 323 56. International Consensus Classification of Mature Lymphoid and Histiocytic/Dendritic Cell Neoplasms - p. 327 57. Introduction to the International Consensus Classification of Mature Lymphoid Neoplasms - p. 327 58. SECTION 11 Mature B-Cell Neoplasms - p. 339 59. 43 Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma and Monoclonal B-Cell Lymphocytosis - p. 340 60. 44 B-Cell Prolymphocytic Leukemia - p. 348 61. 45 Splenic Marginal Zone Lymphoma - p. 351 62. 46 Hairy Cell Leukemia - p. 356 63. 47 Splenic B-Cell Lymphoma/Leukemia, Unclassifiable - p. 360 64. 48 Lymphoplasmacytic Lymphoma - p. 367 65. 49 IgM Monoclonal Gammopathy of Undetermined Significance - p. 373 66. 50 Primary Cold Agglutinin Disease - p. 375 67. 51 Heavy Chain Diseases - p. 377 68. 52 Plasma Cell Neoplasms - p. 384 69. 53 Monoclonal Immunoglobulin Deposition Diseases - p. 403 70. 54 Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue (MALT Lymphoma) - p. 409 71. 55 Primary Cutaneous Marginal Zone Lymphoproliferative Disorder - p. 417 72. 56 Nodal Marginal Zone Lymphoma - p. 421 73. 57 Follicular Lymphoma - p. 427 74. 58 BCL2-Rearrangement Negative, CD23-Positive Follicle Center Lymphoma - p. 441 75. 59 Primary Cutaneous Follicle Center Lymphoma - p. 446 76. 60 Pediatric-Type Follicular Lymphoma - p. 450 77. 61 Testicular Follicular Lymphoma - p. 454 78. 62 Large B-Cell Lymphoma With IRF4 Rearrangement - p. 458 79. 63 Mantle Cell Lymphoma: Conventional and Leukemic Nonnodal Subtypes - p. 462 80. 64 Diffuse Large B-Cell Lymphoma, Not Otherwise Specified - p. 472 81. 65 Large B-Cell Lymphoma With 11q Aberration - p. 481 82. 66 Nodular Lymphocyte Predominant B-Cell Lymphoma - p. 484 83. 67 T-Cell/Histiocyte-Rich Large B-Cell Lymphoma - p. 490 84. 68 Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System - p. 494 85. 69 Primary Diffuse Large B-Cell Lymphoma of the Testis - p. 499 86. 70 Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type - p. 502 87. 71 Intravascular Large B-Cell Lymphoma - p. 505 88. 72 HHV8- and EBV-Negative Primary Effusion-Based Lymphoma - p. 508 89. 73 Epstein-Barr Virus–Positive Mucocutaneous Ulcer - p. 510 90. 74 Epstein-Barr Virus–Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified - p. 514 91. 75 Diffuse Large B-Cell Lymphoma Associated With Chronic Inflammation - p. 518 92. 76 Lymphomatoid Granulomatosis - p. 523 93. 77 Epstein-Barr Virus–Positive Polymorphic B-Cell Lymphoproliferative Disorder, Not Otherwise Specified - p. 527 94. 78 ALK-Positive Large B-Cell Lymphoma - p. 532 95. 79 Plasmablastic Lymphoma - p. 535 96. 80 Human Herpesvirus 8–Associated Lymphoproliferative Disorders - p. 538 97. 81 Burkitt Lymphoma - p. 546 98. 82 High-Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements - p. 552 99. 83 High-Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements - p. 558 100. 84 High-Grade B-Cell Lymphoma, Not Otherwise Specified - p. 561 101. 85 Primary Mediastinal Large B-Cell Lymphoma - p. 564 102. 86 Mediastinal Gray Zone Lymphoma - p. 569 103. 87 Classic Hodgkin Lymphoma - p. 573 104. SECTION 12 Mature T- and NK-Cell Neoplasms - p. 587 105. 88 T-Cell Prolymphocytic Leukemia - p. 588 106. 89 T-Cell Large Granular Lymphocytic Leukemia - p. 594 107. 90 Chronic Lymphoproliferative Disorder of Natural Killer Cells - p. 600 108. 91 Adult T-Cell Leukemia/Lymphoma - p. 604 109. 92 Epstein-Barr Virus-Positive T- and Natural Killer-Cell Lymphoproliferative Disorders of Childhood - p. 613 110. 93 Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type - p. 627 111. 94 Aggressive Natural Killer-Cell Leukemia - p. 635 112. 95 Primary Nodal Epstein-Barr Virus-positive T-Cell/NK-Cell Lymphoma - p. 640 113. 96 Type II Refractory Celiac Disease and Enteropathy-Associated T-Cell Lymphoma - p. 644 114. 97 Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma - p. 655 115. 98 Intestinal T-Cell Lymphoma, Not Otherwise Specified and Indolent Lymphoproliferative Disorders of the Gastrointestinal Tract - p. 660 116. 99 Hepatosplenic T-Cell Lymphoma - p. 667 117. 100 Mycosis Fungoides - p. 672 118. 101 Sézary Syndrome - p. 680 119. 102 Primary Cutaneous CD30-Positive T-Cell Lymphoproliferative Disorders - p. 684 120. 103 Primary Cutaneous CD4-Positive Small/Medium T-Cell Lymphoproliferative Disorder - p. 695 121. 104 Subcutaneous Panniculitis-Like T-Cell Lymphoma - p. 697 122. 105 Primary Cutaneous Gamma-Delta T-Cell Lymphoma - p. 702 123. 106 Primary Cutaneous Acral CD8-Positive T-Cell Lymphoproliferative Disorder - p. 706 124. 107 Primary Cutaneous CD8-Positive Aggressive Epidermotropic Cytotoxic T-Cell Lymphoma - p. 709 125. 108 Peripheral T-Cell Lymphoma, Not Otherwise Specified - p. 712 126. 109 Follicular Helper T-Cell Lymphoma - p. 720 127. 110 Anaplastic Large Cell Lymphoma, ALK Positive - p. 733 128. 111 Anaplastic Large Cell Lymphoma, ALK Negative - p. 741 129. 112 Breast Implant–Associated Anaplastic Large Cell Lymphoma - p. 749 130. SECTION 13 Immunodeficiency-Associated Lymphoproliferative Disorders - p. 753 131. 113 Posttransplant Lymphoproliferative Disorders - p. 754 132. 114 Other Iatrogenic Immunodeficiency-Associated Lymphoproliferative Disorders - p. 769 133. SECTION 14 Histiocytic and Dendritic Cell Neoplasms - p. 777 134. 115 Histiocytic Sarcoma - p. 783 135. 116 Langerhans Cell Histiocytosis - p. 787 136. 117 Indeterminate Dendritic Cell Histiocytosis - p. 791 137. 118 Interdigitating Dendritic Cell Sarcoma - p. 794 138. 119 ALK-Positive Histiocytosis - p. 798 139. 120 Juvenile Xanthogranuloma - p. 803 140. 121 Erdheim-Chester Disease - p. 806 141. 122 Rosai-Dorfman-Destombes Disease - p. 811 142. 123 Follicular Dendritic Cell Sarcoma - p. 816 143. 124 Fibroblastic Reticular Cell Sarcoma - p. 820 144. 125 Epstein-Barr Virus–Positive Inflammatory Follicular Dendritic Cell/Fibroblastic Reticular Cell Tumor - p. 822 145. Index - p. 825
Developed by 149 experts in the field, The International Consensus Classification of Myeloid and Lymphoid Neoplasms provides key information for use at the microscope to assist in arriving at a swift and accurate diagnosis. Drs. Daniel Arber, Michael J. Borowitz, James Cook, Laurence de Leval, John Goodlad, Robert Hasserjian, Rebecca L. King, Hans-Michael Kvasnicka, and Attilio Orazi lead a team of authors who focus on diagnostic criteria and the clinical significance of each disease entity.
1. Introduction to the International Consensus Classification of Myeloid Disorders and Acute Leukemias - p. 1 2. SECTION 1 Myeloproliferative Neoplasms - p. 21 3. 1 Chronic Myeloid Leukemia - p. 22 4. 2 BCR::ABL1-Negative Myeloproliferative Neoplasms - p. 31 5. 3 Chronic Neutrophilic Leukemia - p. 52 6. 4 Chronic Eosinophilic Leukemia, Not Otherwise Specified - p. 56 7. 5 Myeloproliferative Neoplasms, Unclassifiable - p. 61 8. SECTION 2 Myeloid/Lymphoid Neoplasms With Eosinophilia and Tyrosine Kinase Gene Fusions - p. 67 9. 6 Myeloid/Lymphoid Neoplasms With Eosinophilia and Tyrosine Kinase Gene Fusions - p. 68 10. SECTION 3 Mastocytosis - p. 83 11. 7 Mastocytosis - p. 84 12. SECTION 4 Myelodysplastic/Myeloproliferative Neoplasms - p. 101 13. 8 Chronic Myelomonocytic Leukemia - p. 102 14. 9 Atypical Chronic Myeloid Leukemia - p. 110 15. 10 Myelodysplastic/Myeloproliferative Neoplasm With SF3B1 Mutation and Thrombocytosis - p. 114 16. 11 Myelodysplastic/Myeloproliferative Neoplasm, Not Otherwise Specified - p. 118 17. SECTION 5 Premalignant Clonal Cytopenias and Myelodysplastic Syndromes - p. 123 18. Introduction to Premalignant Clonal Cytopenias and Myelodysplastic Syndromes - p. 124 19. 12 Clonal Cytopenia of Undetermined Significance and Other Clonal Cytopenias - p. 127 20. 13 Myelodysplastic Syndrome With Mutated SF3B1 - p. 132 21. 14 Myelodysplastic Syndrome With del(5q) - p. 136 22. 15 Myelodysplastic Syndrome With Mutated TP53 - p. 140 23. 16 Myelodysplastic Syndrome, Not Otherwise Specified - p. 145 24. 17 Myelodysplastic Syndrome With Excess Blasts - p. 150 25. 18 Myelodysplastic Syndrome/Acute Myeloid Leukemia - p. 153 26. SECTION 6 Pediatric and/or Germline Disorders - p. 159 27. 19 Juvenile Myelomonocytic Leukemia - p. 160 28. 20 Refractory Cytopenia of Childhood and Pediatric Myelodysplastic Syndromes - p. 166 29. 21 Hematologic Malignancies With Germline Predisposition - p. 171 30. SECTION 7 Acute Myeloid Leukemias - p. 189 31. 22 Acute Promyelocytic Leukemia With t(15;17)(q24.1;q21.2)/PML::RARA and Acute Promyelocytic Leukemia With Other RARA Rearrangements - p. 190 32. 23 Acute Myeloid Leukemia With t(8;21)(q22;q22.1/RUNX1::RUNX1T1 - p. 194 33. 24 Acute Myeloid Leukemia With inv(16)(p13.1q22) or t(16;16)(p13.1;q22)/CBFB::MYH11 - p. 198 34. 25 Acute Myeloid Leukemia With t(9;11)(p21.3;q23.3)/KMT2A::MLLT3 and Other KMT2A Rearrangements - p. 202 35. 26 Acute Myeloid Leukemia With t(6;9)(p22.3;q34.1)/DEK::NUP214 - p. 208 36. 27 Acute Myeloid Leukemia With inv(3)(q21.3q26.2) or t(3;3)(q21.3;q26.2)/GATA2; MECOM(EVI1) and Acute Myeloid Leukemia With Other MECOM Rearrangements - p. 211 37. 28 Acute Myeloid Leukemia With Other Rare Recurring Translocations - p. 215 38. 29 Acute Myeloid Leukemia With t(9;22)(q34.1;q11.2)/BCR::ABL1 - p. 218 39. 30 Acute Myeloid Leukemia With Mutated NPM1 - p. 221 40. 31 Acute Myeloid Leukemia With In-Frame bZIP CEBPA Mutations - p. 224 41. 32 Acute Myeloid Leukemia and Myelodysplastic Syndrome/Acute Myeloid Leukemia With Mutated TP53 - p. 228 42. 33 Acute Myeloid Leukemia and Myelodysplastic Syndrome/Acute Myeloid Leukemia With Myelodysplasia-Related Gene Mutations - p. 231 43. 34 Acute Myeloid Leukemia and Myelodysplastic Syndrome/Acute Myeloid Leukemia With Myelodysplasia-Related Cytogenetic Abnormalities - p. 234 44. 35 Acute Myeloid Leukemia and Myelodysplastic Syndrome/Acute Myeloid Leukemia, Not Otherwise Specified - p. 237 45. 36 Myeloid Sarcoma - p. 245 46. SECTION 8 Myeloid Proliferations Associated With Down Syndrome - p. 249 47. 37 Myeloid Proliferations Associated With Down Syndrome - p. 250 48. SECTION 9 Blastic Plasmacytoid Dendritic Cell Neoplasm - p. 255 49. 38 Blastic Plasmacytoid Dendritic Cell Neoplasm - p. 256 50. SECTION 10 Lymphoblastic Neoplasms - p. 261 51. Introduction to Lymphoblastic Neoplasms - p. 262 52. 39 Acute Leukemias of Ambiguous Lineage - p. 275 53. 40 B-Lymphoblastic Leukemias/Lymphomas - p. 289 54. 41 T-Lymphoblastic Leukemias/Lymphomas - p. 315 55. 42 NK-Cell Acute Lymphoblastic Leukemia - p. 323 56. International Consensus Classification of Mature Lymphoid and Histiocytic/Dendritic Cell Neoplasms - p. 327 57. Introduction to the International Consensus Classification of Mature Lymphoid Neoplasms - p. 327 58. SECTION 11 Mature B-Cell Neoplasms - p. 339 59. 43 Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma and Monoclonal B-Cell Lymphocytosis - p. 340 60. 44 B-Cell Prolymphocytic Leukemia - p. 348 61. 45 Splenic Marginal Zone Lymphoma - p. 351 62. 46 Hairy Cell Leukemia - p. 356 63. 47 Splenic B-Cell Lymphoma/Leukemia, Unclassifiable - p. 360 64. 48 Lymphoplasmacytic Lymphoma - p. 367 65. 49 IgM Monoclonal Gammopathy of Undetermined Significance - p. 373 66. 50 Primary Cold Agglutinin Disease - p. 375 67. 51 Heavy Chain Diseases - p. 377 68. 52 Plasma Cell Neoplasms - p. 384 69. 53 Monoclonal Immunoglobulin Deposition Diseases - p. 403 70. 54 Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue (MALT Lymphoma) - p. 409 71. 55 Primary Cutaneous Marginal Zone Lymphoproliferative Disorder - p. 417 72. 56 Nodal Marginal Zone Lymphoma - p. 421 73. 57 Follicular Lymphoma - p. 427 74. 58 BCL2-Rearrangement Negative, CD23-Positive Follicle Center Lymphoma - p. 441 75. 59 Primary Cutaneous Follicle Center Lymphoma - p. 446 76. 60 Pediatric-Type Follicular Lymphoma - p. 450 77. 61 Testicular Follicular Lymphoma - p. 454 78. 62 Large B-Cell Lymphoma With IRF4 Rearrangement - p. 458 79. 63 Mantle Cell Lymphoma: Conventional and Leukemic Nonnodal Subtypes - p. 462 80. 64 Diffuse Large B-Cell Lymphoma, Not Otherwise Specified - p. 472 81. 65 Large B-Cell Lymphoma With 11q Aberration - p. 481 82. 66 Nodular Lymphocyte Predominant B-Cell Lymphoma - p. 484 83. 67 T-Cell/Histiocyte-Rich Large B-Cell Lymphoma - p. 490 84. 68 Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System - p. 494 85. 69 Primary Diffuse Large B-Cell Lymphoma of the Testis - p. 499 86. 70 Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type - p. 502 87. 71 Intravascular Large B-Cell Lymphoma - p. 505 88. 72 HHV8- and EBV-Negative Primary Effusion-Based Lymphoma - p. 508 89. 73 Epstein-Barr Virus–Positive Mucocutaneous Ulcer - p. 510 90. 74 Epstein-Barr Virus–Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified - p. 514 91. 75 Diffuse Large B-Cell Lymphoma Associated With Chronic Inflammation - p. 518 92. 76 Lymphomatoid Granulomatosis - p. 523 93. 77 Epstein-Barr Virus–Positive Polymorphic B-Cell Lymphoproliferative Disorder, Not Otherwise Specified - p. 527 94. 78 ALK-Positive Large B-Cell Lymphoma - p. 532 95. 79 Plasmablastic Lymphoma - p. 535 96. 80 Human Herpesvirus 8–Associated Lymphoproliferative Disorders - p. 538 97. 81 Burkitt Lymphoma - p. 546 98. 82 High-Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements - p. 552 99. 83 High-Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements - p. 558 100. 84 High-Grade B-Cell Lymphoma, Not Otherwise Specified - p. 561 101. 85 Primary Mediastinal Large B-Cell Lymphoma - p. 564 102. 86 Mediastinal Gray Zone Lymphoma - p. 569 103. 87 Classic Hodgkin Lymphoma - p. 573 104. SECTION 12 Mature T- and NK-Cell Neoplasms - p. 587 105. 88 T-Cell Prolymphocytic Leukemia - p. 588 106. 89 T-Cell Large Granular Lymphocytic Leukemia - p. 594 107. 90 Chronic Lymphoproliferative Disorder of Natural Killer Cells - p. 600 108. 91 Adult T-Cell Leukemia/Lymphoma - p. 604 109. 92 Epstein-Barr Virus-Positive T- and Natural Killer-Cell Lymphoproliferative Disorders of Childhood - p. 613 110. 93 Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type - p. 627 111. 94 Aggressive Natural Killer-Cell Leukemia - p. 635 112. 95 Primary Nodal Epstein-Barr Virus-positive T-Cell/NK-Cell Lymphoma - p. 640 113. 96 Type II Refractory Celiac Disease and Enteropathy-Associated T-Cell Lymphoma - p. 644 114. 97 Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma - p. 655 115. 98 Intestinal T-Cell Lymphoma, Not Otherwise Specified and Indolent Lymphoproliferative Disorders of the Gastrointestinal Tract - p. 660 116. 99 Hepatosplenic T-Cell Lymphoma - p. 667 117. 100 Mycosis Fungoides - p. 672 118. 101 Sézary Syndrome - p. 680 119. 102 Primary Cutaneous CD30-Positive T-Cell Lymphoproliferative Disorders - p. 684 120. 103 Primary Cutaneous CD4-Positive Small/Medium T-Cell Lymphoproliferative Disorder - p. 695 121. 104 Subcutaneous Panniculitis-Like T-Cell Lymphoma - p. 697 122. 105 Primary Cutaneous Gamma-Delta T-Cell Lymphoma - p. 702 123. 106 Primary Cutaneous Acral CD8-Positive T-Cell Lymphoproliferative Disorder - p. 706 124. 107 Primary Cutaneous CD8-Positive Aggressive Epidermotropic Cytotoxic T-Cell Lymphoma - p. 709 125. 108 Peripheral T-Cell Lymphoma, Not Otherwise Specified - p. 712 126. 109 Follicular Helper T-Cell Lymphoma - p. 720 127. 110 Anaplastic Large Cell Lymphoma, ALK Positive - p. 733 128. 111 Anaplastic Large Cell Lymphoma, ALK Negative - p. 741 129. 112 Breast Implant–Associated Anaplastic Large Cell Lymphoma - p. 749 130. SECTION 13 Immunodeficiency-Associated Lymphoproliferative Disorders - p. 753 131. 113 Posttransplant Lymphoproliferative Disorders - p. 754 132. 114 Other Iatrogenic Immunodeficiency-Associated Lymphoproliferative Disorders - p. 769 133. SECTION 14 Histiocytic and Dendritic Cell Neoplasms - p. 777 134. 115 Histiocytic Sarcoma - p. 783 135. 116 Langerhans Cell Histiocytosis - p. 787 136. 117 Indeterminate Dendritic Cell Histiocytosis - p. 791 137. 118 Interdigitating Dendritic Cell Sarcoma - p. 794 138. 119 ALK-Positive Histiocytosis - p. 798 139. 120 Juvenile Xanthogranuloma - p. 803 140. 121 Erdheim-Chester Disease - p. 806 141. 122 Rosai-Dorfman-Destombes Disease - p. 811 142. 123 Follicular Dendritic Cell Sarcoma - p. 816 143. 124 Fibroblastic Reticular Cell Sarcoma - p. 820 144. 125 Epstein-Barr Virus–Positive Inflammatory Follicular Dendritic Cell/Fibroblastic Reticular Cell Tumor - p. 822 145. Index - p. 825