Emerging Trends in Phytotherapy of Cancer is an essential reference that explores the multifaceted role of medicinal plants in combating cancer. The book covers a broad range of interconnected topics including ethnomedicinal plants used in cancer by tribes and aboriginals, herbs used in Ayurvedic medicine for cancer, integrated approaches of modern and conventional drugs, anti-cancerous secondary metabolites, plant-based anticancer drugs approved by FDA and WHO, toxicity to humans, and the role of emerging technologies such as the applications of nanotechnology and artificial intelligence. The contents are divided into six parts. Part one opens with an introductory chapter, followed by the different combinations of plant-based drugs and modern medicine for cancer treatment, and recent developments in cancer research. Part two discusses the ethnomedicinal uses of plants in cancer and the role of Ayurvedic herbal medicines in cancer. Part three incorporates the role of secondary metabolites in cancer treatment. Part four elaborates on the plant-based drugs recommended by FDA/WHO. Part five concerns the human phytotoxicity of secondary metabolites, and part six describes the role of emerging nanotechnologies and artificial intelligence in phytotherapy drug delivery and treatment. Targeted at researchers, healthcare professionals, and advanced students in related fields, this book provides technical and in-depth knowledge, contributing to ongoing advancements in cancer treatment. It uniquely integrates ethnomedicinal therapies with modern technologies, offering a comprehensive overview of the research into phytomedicinal cancer therapies.
1. Section 1: Introduction to phytotherapy for cancer - p. S1 2. Chapter 1. Introduction to phytotherapy in cancer treatment - p. 3 3. Chapter 2. Interaction between plant-based drugs and cancer drugs—efficacy and side effects - p. 13 4. Chapter 3. Recent developments in bioactive compounds from plants for cancer treatment - p. 31 5. Section 2: Ethnomedicinal uses of plants in cancer treatment - p. S45 6. Chapter 4. Ethnomedicinal plants used in cancer treatment - p. 47 7. Chapter 5. Ayurvedic herbs in oncological care: traditional wisdom meets translational science - p. 59 8. Chapter 6. Alternative natural therapies in treatment of cancer - p. 81 9. Section 3: Role of secondary metabolites in cancer treatment - p. S107 10. Chapter 7. Alkaloids as novel agents in cancer treatment - p. 109 11. Chapter 8. Flavonoids in cancer treatment: structures, mechanisms, and future directions - p. 127 12. Chapter 9. Phytocannabinoids as bioassay targets in anticancer chemotherapy - p. 137 13. Chapter 10. Terpenoids and phenolics as human colon anticancer agents - p. 161 14. Chapter 11. Glycosides in cancer treatment - p. 177 15. Chapter 12. Role of saponins in cancer therapy - p. 191 16. Chapter 13. Techniques of extraction of medicinal plants, quality assessment, and reproducibility - p. 209 17. Chapter 14. Synergistic effects of secondary metabolites in cancer treatment - p. 227 18. Section 4: Plant-based drugs for cancer recommended by FDA/WHO - p. S245 19. Chapter 15. FDA-approved plant-based drugs for cancer treatment - p. 247 20. Chapter 16. WHO-recommended plant-based therapies for cancer - p. 263 21. Chapter 17. Case study of notable plant-based drugs - p. 291 22. Chapter 18. Clinical applications and advancements in camptothecin-based cancer therapies - p. 311 23. Section 5: Phytotoxicity of secondary metabolites and essential oils - p. S325 24. Chapter 19. Toxicity of key secondary metabolites and essential oils used in cancer - p. 327 25. Chapter 20. Regulatory and ethical considerations in toxicity of plant-based drugs used in cancer - p. 341 26. Section 6: Nanotechnology and AI applications in medicinal plants used in cancer - p. S355 27. Chapter 21. Emerging trends in phytotherapy of cancer: utilizing carbon dots derived from ayurvedic medicinal plants to treat cancer - p. 357 28. Chapter 22. Nanocomposites using bioactive metabolites derived from medicinal and aromatic plants to combat cancer - p. 377 29. Chapter 23. Nanotechnology-based drug delivery of natural products in cancer - p. 401 30. Chapter 24. Targeting triple-negative breast cancer signaling via phytonanomedicine - p. 421 31. Chapter 25. Artificial intelligence driven discovery of anticancer phytochemicals: from plants to lead compounds - p. 441 32. Chapter 26. Emerging machine learning techniques for the development and analysis of anticancer drugs from plants - p. 461 33. Index - p. 495
Emerging Trends in Phytotherapy of Cancer is an essential reference that explores the multifaceted role of medicinal plants in combating cancer. The book covers a broad range of interconnected topics including ethnomedicinal plants used in cancer by tribes and aboriginals, herbs used in Ayurvedic medicine for cancer, integrated approaches of modern and conventional drugs, anti-cancerous secondary metabolites, plant-based anticancer drugs approved by FDA and WHO, toxicity to humans, and the role of emerging technologies such as the applications of nanotechnology and artificial intelligence. The contents are divided into six parts. Part one opens with an introductory chapter, followed by the different combinations of plant-based drugs and modern medicine for cancer treatment, and recent developments in cancer research. Part two discusses the ethnomedicinal uses of plants in cancer and the role of Ayurvedic herbal medicines in cancer. Part three incorporates the role of secondary metabolites in cancer treatment. Part four elaborates on the plant-based drugs recommended by FDA/WHO. Part five concerns the human phytotoxicity of secondary metabolites, and part six describes the role of emerging nanotechnologies and artificial intelligence in phytotherapy drug delivery and treatment. Targeted at researchers, healthcare professionals, and advanced students in related fields, this book provides technical and in-depth knowledge, contributing to ongoing advancements in cancer treatment. It uniquely integrates ethnomedicinal therapies with modern technologies, offering a comprehensive overview of the research into phytomedicinal cancer therapies.
1. Section 1: Introduction to phytotherapy for cancer - p. S1 2. Chapter 1. Introduction to phytotherapy in cancer treatment - p. 3 3. Chapter 2. Interaction between plant-based drugs and cancer drugs—efficacy and side effects - p. 13 4. Chapter 3. Recent developments in bioactive compounds from plants for cancer treatment - p. 31 5. Section 2: Ethnomedicinal uses of plants in cancer treatment - p. S45 6. Chapter 4. Ethnomedicinal plants used in cancer treatment - p. 47 7. Chapter 5. Ayurvedic herbs in oncological care: traditional wisdom meets translational science - p. 59 8. Chapter 6. Alternative natural therapies in treatment of cancer - p. 81 9. Section 3: Role of secondary metabolites in cancer treatment - p. S107 10. Chapter 7. Alkaloids as novel agents in cancer treatment - p. 109 11. Chapter 8. Flavonoids in cancer treatment: structures, mechanisms, and future directions - p. 127 12. Chapter 9. Phytocannabinoids as bioassay targets in anticancer chemotherapy - p. 137 13. Chapter 10. Terpenoids and phenolics as human colon anticancer agents - p. 161 14. Chapter 11. Glycosides in cancer treatment - p. 177 15. Chapter 12. Role of saponins in cancer therapy - p. 191 16. Chapter 13. Techniques of extraction of medicinal plants, quality assessment, and reproducibility - p. 209 17. Chapter 14. Synergistic effects of secondary metabolites in cancer treatment - p. 227 18. Section 4: Plant-based drugs for cancer recommended by FDA/WHO - p. S245 19. Chapter 15. FDA-approved plant-based drugs for cancer treatment - p. 247 20. Chapter 16. WHO-recommended plant-based therapies for cancer - p. 263 21. Chapter 17. Case study of notable plant-based drugs - p. 291 22. Chapter 18. Clinical applications and advancements in camptothecin-based cancer therapies - p. 311 23. Section 5: Phytotoxicity of secondary metabolites and essential oils - p. S325 24. Chapter 19. Toxicity of key secondary metabolites and essential oils used in cancer - p. 327 25. Chapter 20. Regulatory and ethical considerations in toxicity of plant-based drugs used in cancer - p. 341 26. Section 6: Nanotechnology and AI applications in medicinal plants used in cancer - p. S355 27. Chapter 21. Emerging trends in phytotherapy of cancer: utilizing carbon dots derived from ayurvedic medicinal plants to treat cancer - p. 357 28. Chapter 22. Nanocomposites using bioactive metabolites derived from medicinal and aromatic plants to combat cancer - p. 377 29. Chapter 23. Nanotechnology-based drug delivery of natural products in cancer - p. 401 30. Chapter 24. Targeting triple-negative breast cancer signaling via phytonanomedicine - p. 421 31. Chapter 25. Artificial intelligence driven discovery of anticancer phytochemicals: from plants to lead compounds - p. 441 32. Chapter 26. Emerging machine learning techniques for the development and analysis of anticancer drugs from plants - p. 461 33. Index - p. 495
