The new 4th edition of Histopathology of Preclinical Toxicity Studies is now completely in full color and continues to describe the pathology found in drug safety studies in laboratory animals with an evidence-based discussion of the relevance of these findings to the clinical investigation of new drugs for humans. Organized according to organ systems, this revision features a thoroughly updated bibliography and discusses new drug-induced pathologies and applicable species comparisons to aid in the preclinical safety assessment of new medicines. This updated reference is essential for those involved in drug safety evaluation, including pathologists, toxicologists and pharmacologists working in corporate, government, academic and research settings.
1. Chapter 1. Introduction 2. Chapter 2. Integumentary System 3. Chapter 3. Mammary Gland 4. Chapter 4. Hemopoietic and Lymphatic Systems 5. Chapter 5. Musculoskeletal System 6. Chapter 6. Respiratory Tract 7. Chapter 7. Cardiovascular System 8. Chapter 8. Digestive System 9. Mouth and oropharynx 10. Salivary glands 11. Esophagus 12. Forestomach 13. Stomach (glandular) 14. Small intestine 15. Large intestine 16. References 17. Chapter 9. Liver and Pancreas 18. Liver 19. Bile ducts, biliary system 20. Gallbladder 21. Exocrine pancreas 22. Endocrine Pancreas 23. References 24. Chapter 10. Urinary Tract 25. Kidney 26. Urinary bladder 27. Neoplasia 28. References 29. Chapter 11. Male Genital Tract 30. Chapter 12. Female Genital Tract 31. Chapter 13. Endocrine Glands 32. Pituitary gland 33. Adrenal gland 34. Thyroid gland 35. Parathyroid gland 36. References 37. Chapter 14. Nervous System and Special Sense Organs 38. Index
The new 4th edition of Histopathology of Preclinical Toxicity Studies is now completely in full color and continues to describe the pathology found in drug safety studies in laboratory animals with an evidence-based discussion of the relevance of these findings to the clinical investigation of new drugs for humans. Organized according to organ systems, this revision features a thoroughly updated bibliography and discusses new drug-induced pathologies and applicable species comparisons to aid in the preclinical safety assessment of new medicines. This updated reference is essential for those involved in drug safety evaluation, including pathologists, toxicologists and pharmacologists working in corporate, government, academic and research settings.
1. Chapter 1. Introduction 2. Chapter 2. Integumentary System 3. Chapter 3. Mammary Gland 4. Chapter 4. Hemopoietic and Lymphatic Systems 5. Chapter 5. Musculoskeletal System 6. Chapter 6. Respiratory Tract 7. Chapter 7. Cardiovascular System 8. Chapter 8. Digestive System 9. Mouth and oropharynx 10. Salivary glands 11. Esophagus 12. Forestomach 13. Stomach (glandular) 14. Small intestine 15. Large intestine 16. References 17. Chapter 9. Liver and Pancreas 18. Liver 19. Bile ducts, biliary system 20. Gallbladder 21. Exocrine pancreas 22. Endocrine Pancreas 23. References 24. Chapter 10. Urinary Tract 25. Kidney 26. Urinary bladder 27. Neoplasia 28. References 29. Chapter 11. Male Genital Tract 30. Chapter 12. Female Genital Tract 31. Chapter 13. Endocrine Glands 32. Pituitary gland 33. Adrenal gland 34. Thyroid gland 35. Parathyroid gland 36. References 37. Chapter 14. Nervous System and Special Sense Organs 38. Index
