mRNA Therapeutics: Foundations, Innovations, and Clinical Applications summarizes the scientific development of mRNA vaccines that have revolutionized the way we treat disease. This approach has the potential to treat a wide range of diseases, including COVID-19, cancer, and infectious diseases. The first section of the book introduces mRNA vaccines, including their history, mechanism of action, and potential applications. The second section delves into the science of mRNA vaccines, covering topics such as the structure of mRNA, the delivery of mRNA to cells, and the immune response to mRNA vaccines.
The third section discusses the future of mRNA technology, exploring potential applications such as cancer therapy, prevention of infectious diseases, and replacement of missing or damaged proteins. This is a valuable resource for scientists, researchers, and clinicians who are interested in the latest developments in mRNA technology. It is also a useful reference for students and professionals who are working in the fields of biotechnology, pharmaceutical science, and vaccine development.
1. Introduction - p. Page vi 2. List of Illustrations - p. Page ix 3. List of Tables - p. Page x 4. Chapter 1 : Introduction to mRNA and mRNA-based therapeutics - p. Page x 5. Chapter 2 : Overview of the immune system and introduction to vaccines - p. Page 20 6. Chapter 3 : The science of mRNA: structure, design innovations and synthesis via IVT - p. Page 62 7. Chapter 4 : Delivery systems for mRNA - p. Page 91 8. Chapter 5 : mRNA vaccines for COVID-19 - p. Page 118 9. Chapter 6 : mRNA-based cancer therapeutics - p. Page 150 10. Chapter 7 : Further therapeutic applications of mRNA and saRNA - p. Page 182 11. Chapter 8 : Vaccine efficacy, safety, and regulatory controls - p. Page 213 12. Chapter 9 : mRNA vaccines: public health and societal challenges - p. Page 244 13. Conclusions - p. Page 268 14. Index - p. Page 285
mRNA Therapeutics: Foundations, Innovations, and Clinical Applications summarizes the scientific development of mRNA vaccines that have revolutionized the way we treat disease. This approach has the potential to treat a wide range of diseases, including COVID-19, cancer, and infectious diseases. The first section of the book introduces mRNA vaccines, including their history, mechanism of action, and potential applications. The second section delves into the science of mRNA vaccines, covering topics such as the structure of mRNA, the delivery of mRNA to cells, and the immune response to mRNA vaccines.
The third section discusses the future of mRNA technology, exploring potential applications such as cancer therapy, prevention of infectious diseases, and replacement of missing or damaged proteins. This is a valuable resource for scientists, researchers, and clinicians who are interested in the latest developments in mRNA technology. It is also a useful reference for students and professionals who are working in the fields of biotechnology, pharmaceutical science, and vaccine development.
1. Introduction - p. Page vi 2. List of Illustrations - p. Page ix 3. List of Tables - p. Page x 4. Chapter 1 : Introduction to mRNA and mRNA-based therapeutics - p. Page x 5. Chapter 2 : Overview of the immune system and introduction to vaccines - p. Page 20 6. Chapter 3 : The science of mRNA: structure, design innovations and synthesis via IVT - p. Page 62 7. Chapter 4 : Delivery systems for mRNA - p. Page 91 8. Chapter 5 : mRNA vaccines for COVID-19 - p. Page 118 9. Chapter 6 : mRNA-based cancer therapeutics - p. Page 150 10. Chapter 7 : Further therapeutic applications of mRNA and saRNA - p. Page 182 11. Chapter 8 : Vaccine efficacy, safety, and regulatory controls - p. Page 213 12. Chapter 9 : mRNA vaccines: public health and societal challenges - p. Page 244 13. Conclusions - p. Page 268 14. Index - p. Page 285
