Selected as a Doody's Core Title for 2022!Defining the field of immunology for 40 years, Paul’s Fundamental Immunology continues to provide detailed, authoritative, up-to-date information that uniquely bridges the gap between basic immunology and the disease process. The fully revised 8th edition maintains the excellence established by Dr. William E. Paul, who passed away in 2015, and is now under new editorial leadership of Drs. Martin F. Flajnik, Nevil J. Singh, and Steven M. Holland. It’s an ideal reference and gold standard text for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role.
1. Section I. Introduction to Immunology - p. 1 2. 1 Overview of the Immune System - p. 1 3. 2 History of Immunology - p. 29 4. Section II. Evolution of the Immune System - p. 52 5. 3 The Insect Immune System - p. 52 6. 4 Evolution of the Vertebrate and Lower Deuterostome Immune System - p. 79 7. 5 The Plant Immune System - p. 134 8. Section III. Cellular Pathways and Processes in Immunity - p. 161 9. 6 Immunometabolism - p. 161 10. 7 Regulated Cell Death in the Immune System - p. 204 11. 8 Lymphoid Tissues and Organs - p. 228 12. 9 Type I Cytokines, Interferons, and Their Receptors - p. 258 13. 10 Tumor Necrosis Factor Superfamily of Cytokines and Receptors - p. 308 14. 11 Chemokines and Chemokine Receptors - p. 344 15. Section IV. Innate Immunity - p. 386 16. 12 Pattern Recognition Receptors and the IL-1 Family - p. 386 17. 13 The Complement System - p. 416 18. 14 Neutrophils - p. 455 19. 15 Macrophages - p. 469 20. 16 Mast Cells and Basophils - p. 487 21. 17 Eosinophils - p. 519 22. 18 The Biology of Natural Killer Cells and Innate Lymphoid Cells - p. 537 23. Section V. Adaptive Immunity - p. 573 24. 19 The Major Histocompatibility Complex - p. 573 25. 20 Classical Antigen Processing and Presentation - p. 622 26. 21 Immunoglobulins: Structure and Function - p. 644 27. 22 Immunoglobulins: Molecular Genetics - p. 671 28. 23 T Cell Antigen Receptors and Antigen Recognition - p. 702 29. 24 Antigen Receptor Signaling - p. 734 30. 25 B Cell Development in Mice - p. 774 31. 26 B Cell Responses - p. 798 32. 27 T Cell Development in the Thymus - p. 823 33. 28 CD4+ Helper T Cells: Differentiation, Flexibility, and Heterogeneity - p. 856 34. 29 Regulatory T Cells - p. 874 35. 30 CD8+ T Cell Memory - p. 924 36. 31 Cytotoxic Effector Functions - p. 944 37. Section VI. Integrative Immunology - p. 971 38. 32 Immunologic Tolerance - p. 971 39. 33 Fc Receptors and Their Role in Immune Regulation and Inflammation - p. 1008 40. 34 Dendritic cells - p. 1034 41. 35 Gamma Delta T Cells - p. 1054 42. 36 CD1-Restricted T Cells - p. 1102 43. 37 Mucosal-Associated Invariant T Cells and Other MR1-Reactive T Cells - p. 1137 44. 38 The Mucosal Immune System - p. 1178 45. 39 Introduction to Neuroimmunology - p. 1212 46. 40 Vaccines - p. 1231 47. 41 Maternal-Fetal Immunology - p. 1283 48. Section VII. Immune Responses to Pathogens - p. 1325 49. 42 Response to Parasites - p. 1325 50. 43 Immune Responses to Bacteria - p. 1355 51. 44 Response to Viruses - p. 1399 52. 45 Immunology of HIV Infection - p. 1445 53. Section VIII. Immunological Disease States and Immunodeficiency - p. 1465 54. 46 Autoimmunity and Autoimmune Diseases - p. 1465 55. 47 Immunologic Mechanisms of Allergic Disorders - p. 1515 56. 48 Transplantation Immunology - p. 1549 57. 49 Cancer Immunology and Immunotherapy - p. 1589 58. 50 Inborn Errors of Immunity - p. 1619 59. Index - p. 1649
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Selected as a Doody's Core Title for 2022!Defining the field of immunology for 40 years, Paul’s Fundamental Immunology continues to provide detailed, authoritative, up-to-date information that uniquely bridges the gap between basic immunology and the disease process. The fully revised 8th edition maintains the excellence established by Dr. William E. Paul, who passed away in 2015, and is now under new editorial leadership of Drs. Martin F. Flajnik, Nevil J. Singh, and Steven M. Holland. It’s an ideal reference and gold standard text for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role.
1. Section I. Introduction to Immunology - p. 1 2. 1 Overview of the Immune System - p. 1 3. 2 History of Immunology - p. 29 4. Section II. Evolution of the Immune System - p. 52 5. 3 The Insect Immune System - p. 52 6. 4 Evolution of the Vertebrate and Lower Deuterostome Immune System - p. 79 7. 5 The Plant Immune System - p. 134 8. Section III. Cellular Pathways and Processes in Immunity - p. 161 9. 6 Immunometabolism - p. 161 10. 7 Regulated Cell Death in the Immune System - p. 204 11. 8 Lymphoid Tissues and Organs - p. 228 12. 9 Type I Cytokines, Interferons, and Their Receptors - p. 258 13. 10 Tumor Necrosis Factor Superfamily of Cytokines and Receptors - p. 308 14. 11 Chemokines and Chemokine Receptors - p. 344 15. Section IV. Innate Immunity - p. 386 16. 12 Pattern Recognition Receptors and the IL-1 Family - p. 386 17. 13 The Complement System - p. 416 18. 14 Neutrophils - p. 455 19. 15 Macrophages - p. 469 20. 16 Mast Cells and Basophils - p. 487 21. 17 Eosinophils - p. 519 22. 18 The Biology of Natural Killer Cells and Innate Lymphoid Cells - p. 537 23. Section V. Adaptive Immunity - p. 573 24. 19 The Major Histocompatibility Complex - p. 573 25. 20 Classical Antigen Processing and Presentation - p. 622 26. 21 Immunoglobulins: Structure and Function - p. 644 27. 22 Immunoglobulins: Molecular Genetics - p. 671 28. 23 T Cell Antigen Receptors and Antigen Recognition - p. 702 29. 24 Antigen Receptor Signaling - p. 734 30. 25 B Cell Development in Mice - p. 774 31. 26 B Cell Responses - p. 798 32. 27 T Cell Development in the Thymus - p. 823 33. 28 CD4+ Helper T Cells: Differentiation, Flexibility, and Heterogeneity - p. 856 34. 29 Regulatory T Cells - p. 874 35. 30 CD8+ T Cell Memory - p. 924 36. 31 Cytotoxic Effector Functions - p. 944 37. Section VI. Integrative Immunology - p. 971 38. 32 Immunologic Tolerance - p. 971 39. 33 Fc Receptors and Their Role in Immune Regulation and Inflammation - p. 1008 40. 34 Dendritic cells - p. 1034 41. 35 Gamma Delta T Cells - p. 1054 42. 36 CD1-Restricted T Cells - p. 1102 43. 37 Mucosal-Associated Invariant T Cells and Other MR1-Reactive T Cells - p. 1137 44. 38 The Mucosal Immune System - p. 1178 45. 39 Introduction to Neuroimmunology - p. 1212 46. 40 Vaccines - p. 1231 47. 41 Maternal-Fetal Immunology - p. 1283 48. Section VII. Immune Responses to Pathogens - p. 1325 49. 42 Response to Parasites - p. 1325 50. 43 Immune Responses to Bacteria - p. 1355 51. 44 Response to Viruses - p. 1399 52. 45 Immunology of HIV Infection - p. 1445 53. Section VIII. Immunological Disease States and Immunodeficiency - p. 1465 54. 46 Autoimmunity and Autoimmune Diseases - p. 1465 55. 47 Immunologic Mechanisms of Allergic Disorders - p. 1515 56. 48 Transplantation Immunology - p. 1549 57. 49 Cancer Immunology and Immunotherapy - p. 1589 58. 50 Inborn Errors of Immunity - p. 1619 59. Index - p. 1649
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