Internationally renowned experts present topics related to obesity, nutrition, and liver disease in this issue. In the first article, the epidemiology of obesity and its association with liver disease are covered. The following two articles focus on the roles that visceral adipose tissue and microbiota potentially play in the pathogenesis of obesity-related liver disease. The next article focuses on the hepatic pathology seen in patients with obesity-related liver disease and those with malnutrition. The next five articles are focused on NAFLD and provide in-depth data on the natural history and treatment strategies for patients with NAFLD. The next six articles deal with the impact of obesity on other liver diseases and on special populations including children and liver-transplant recipients. The final article provides the most updated information regarding genomics and genetic targets that may provide better prognostic and diagnostic biomarkers and more personalized treatment targets for patients with NAFLD. Cutting-edge information in this issue will help readers gain better understanding of the natural history and pathogenesis of primary and secondary liver diseases associated with obesity. As the information about obesity-related liver disease expands, clinicians will be able to provide more targeted therapeutic options for these patients and develop more accurate diagnostic and prognostic biomarkers.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Contributors - p. 4 5. Forthcoming Issues - p. 8 6. Preface: Obesity and Liver Disease - p. 9 7. Obesity and Liver Disease - p. 10 8. Obesity-Associated Nonalcoholic Fatty Liver Disease - p. 20 9. The Impact of Obesity on Liver Histology - p. 28 10. New Potential Pathways for the Pathogenesis of NAFLD - p. 32 11. Adipose Tissue as an Endocrine Organ - p. 33 12. Obesity and NAFLD - p. 43 13. Treatment - p. 51 14. The Role of Medications for the Management of Patients with NAFLD - p. 52 15. The Role of Diet and Nutritional Intervention for the Management of Patients with NAFLD - p. 62 16. Role of Exercise in Optimizing the Functional Status of Patients with Nonalcoholic Fatty Liver Disease - p. 73 17. Surgical Management of Obesity in Patients with Morbid Obesity and Nonalcoholic Fatty Liver Disease - p. 83 18. Obesity, Nutrition, and Other Liver Diseases - p. 91 19. The Impact of Obesity and Metabolic Syndrome on Chronic Hepatitis C - p. 92 20. The Impact of Obesity and Metabolic Syndrome on Alcoholic Liver Disease - p. 99 21. The Impact of Obesity and Metabolic Syndrome on Chronic Hepatitis B and Drug-Induced Liver Disease - p. 103 22. Special Topics - p. 111 23. Nutrition in Cirrhosis and Chronic Liver Disease - p. 112 24. Obesity and Liver Cancer - p. 120 25. Impact of Nutrition and Obesity on Chronic Liver Disease - p. 127 26. Obesity, Nutrition, and Liver Disease in Children - p. 135 27. The Interactions of Nonalcoholic Fatty Liver Disease and Cardiovascular Diseases - p. 143 28. Host Genetic Variants in Obesity-Related Nonalcoholic Fatty Liver Disease - p. 150 29. Index - p. 162
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Internationally renowned experts present topics related to obesity, nutrition, and liver disease in this issue. In the first article, the epidemiology of obesity and its association with liver disease are covered. The following two articles focus on the roles that visceral adipose tissue and microbiota potentially play in the pathogenesis of obesity-related liver disease. The next article focuses on the hepatic pathology seen in patients with obesity-related liver disease and those with malnutrition. The next five articles are focused on NAFLD and provide in-depth data on the natural history and treatment strategies for patients with NAFLD. The next six articles deal with the impact of obesity on other liver diseases and on special populations including children and liver-transplant recipients. The final article provides the most updated information regarding genomics and genetic targets that may provide better prognostic and diagnostic biomarkers and more personalized treatment targets for patients with NAFLD. Cutting-edge information in this issue will help readers gain better understanding of the natural history and pathogenesis of primary and secondary liver diseases associated with obesity. As the information about obesity-related liver disease expands, clinicians will be able to provide more targeted therapeutic options for these patients and develop more accurate diagnostic and prognostic biomarkers.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Contributors - p. 4 5. Forthcoming Issues - p. 8 6. Preface: Obesity and Liver Disease - p. 9 7. Obesity and Liver Disease - p. 10 8. Obesity-Associated Nonalcoholic Fatty Liver Disease - p. 20 9. The Impact of Obesity on Liver Histology - p. 28 10. New Potential Pathways for the Pathogenesis of NAFLD - p. 32 11. Adipose Tissue as an Endocrine Organ - p. 33 12. Obesity and NAFLD - p. 43 13. Treatment - p. 51 14. The Role of Medications for the Management of Patients with NAFLD - p. 52 15. The Role of Diet and Nutritional Intervention for the Management of Patients with NAFLD - p. 62 16. Role of Exercise in Optimizing the Functional Status of Patients with Nonalcoholic Fatty Liver Disease - p. 73 17. Surgical Management of Obesity in Patients with Morbid Obesity and Nonalcoholic Fatty Liver Disease - p. 83 18. Obesity, Nutrition, and Other Liver Diseases - p. 91 19. The Impact of Obesity and Metabolic Syndrome on Chronic Hepatitis C - p. 92 20. The Impact of Obesity and Metabolic Syndrome on Alcoholic Liver Disease - p. 99 21. The Impact of Obesity and Metabolic Syndrome on Chronic Hepatitis B and Drug-Induced Liver Disease - p. 103 22. Special Topics - p. 111 23. Nutrition in Cirrhosis and Chronic Liver Disease - p. 112 24. Obesity and Liver Cancer - p. 120 25. Impact of Nutrition and Obesity on Chronic Liver Disease - p. 127 26. Obesity, Nutrition, and Liver Disease in Children - p. 135 27. The Interactions of Nonalcoholic Fatty Liver Disease and Cardiovascular Diseases - p. 143 28. Host Genetic Variants in Obesity-Related Nonalcoholic Fatty Liver Disease - p. 150 29. Index - p. 162
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