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From speech to breathing to overt movement contractions of muscles are the only way other than sweating whereby we literally make a mark on the world. Locomotion is an essential part of this equation and exciting new developments are shedding light on the mechanisms underlying how this important behavior occurs.

The Neural Control of Movement discusses these developments across a variety of species including man. The editors focus on highlighting the utility of different models from invertebrates to vertebrates. Each chapter discusses how new approaches in neuroscience are being used to dissect and control neural networks. An area of emphasis is on vertebrate motor networks and particularly the spinal cord. The spinal cord is unique because it has seen the use of genetic tools allowing the dissection of networks for over ten years. This book provides practical details on model systems, approaches, and analysis approaches related to movement control. This book is written for neuroscientists interested in movement control.

  • Provides practice details on model systems, approaches, and analysis approaches related to movement control
  • Discusses how recent advances like optogenetics and chemogenetics affect the need for model systems to be modified (or not) to work for studies of movement and motor control
  • Written for neuroscientists interested in movement control, especially movement disorders like Parkinson’s, MS, spinal cord injury, and stroke

1. Introduction: An interphyletic tool kit to study locomotor function: Past, present, and future directions - p. page_xxi 2. Section I: Invertebrates - p. page_xlv 3. Chapter 1: Elegantly - p. page_3 4. Chapter 2: Small steps and larger strides in understanding the neural bases of crawling in the medicinal leech - p. page_31 5. Chapter 3: Studying the neural basis of animal walking in the stick insect - p. page_57 6. Chapter 4: Neural control of flight in locusts - p. page_75 7. Section II: Vertebrates - p. page_95 8. Chapter 5: Neural control of swimming in lampreys - p. page_99 9. Chapter 6: Toward a comprehensive model of circuits underlying locomotion: What did we learn from zebrafish? - p. page_125 10. Chapter 7: Neural control of swimming in hatchling Xenopus frog tadpoles - p. page_153 11. Chapter 8: Xenopus frog metamorphosis: A model for studying locomotor network development and neuromodulation - p. page_175 12. Chapter 9: The turtle as a model for spinal motor circuits - p. page_205 13. Chapter 10: Development of the locomotor system—Chick embryo - p. page_221 14. Chapter 11: Using mouse genetics to study the developing spinal locomotor circuit - p. page_237 15. Chapter 12: Using mouse genetics to investigate supraspinal pathways of the brain important to locomotion - p. page_269 16. Chapter 13: Fundamental contributions of the cat model to the neural control of locomotion - p. page_315 17. Chapter 14: The micropig model of neurosurgery and spinal cord injury in experiments of motor control - p. page_349 18. Chapter 15: What lies beneath the brain: Neural circuits involved in human locomotion - p. page_385 19. Chapter 16: A tale of many models. Which one creates the best of times? - p. page_419 20. Index - p. page_427

Descripcion
Descripción

From speech to breathing to overt movement contractions of muscles are the only way other than sweating whereby we literally make a mark on the world. Locomotion is an essential part of this equation and exciting new developments are shedding light on the mechanisms underlying how this important behavior occurs.

The Neural Control of Movement discusses these developments across a variety of species including man. The editors focus on highlighting the utility of different models from invertebrates to vertebrates. Each chapter discusses how new approaches in neuroscience are being used to dissect and control neural networks. An area of emphasis is on vertebrate motor networks and particularly the spinal cord. The spinal cord is unique because it has seen the use of genetic tools allowing the dissection of networks for over ten years. This book provides practical details on model systems, approaches, and analysis approaches related to movement control. This book is written for neuroscientists interested in movement control.

  • Provides practice details on model systems, approaches, and analysis approaches related to movement control
  • Discusses how recent advances like optogenetics and chemogenetics affect the need for model systems to be modified (or not) to work for studies of movement and motor control
  • Written for neuroscientists interested in movement control, especially movement disorders like Parkinson’s, MS, spinal cord injury, and stroke

1. Introduction: An interphyletic tool kit to study locomotor function: Past, present, and future directions - p. page_xxi 2. Section I: Invertebrates - p. page_xlv 3. Chapter 1: Elegantly - p. page_3 4. Chapter 2: Small steps and larger strides in understanding the neural bases of crawling in the medicinal leech - p. page_31 5. Chapter 3: Studying the neural basis of animal walking in the stick insect - p. page_57 6. Chapter 4: Neural control of flight in locusts - p. page_75 7. Section II: Vertebrates - p. page_95 8. Chapter 5: Neural control of swimming in lampreys - p. page_99 9. Chapter 6: Toward a comprehensive model of circuits underlying locomotion: What did we learn from zebrafish? - p. page_125 10. Chapter 7: Neural control of swimming in hatchling Xenopus frog tadpoles - p. page_153 11. Chapter 8: Xenopus frog metamorphosis: A model for studying locomotor network development and neuromodulation - p. page_175 12. Chapter 9: The turtle as a model for spinal motor circuits - p. page_205 13. Chapter 10: Development of the locomotor system—Chick embryo - p. page_221 14. Chapter 11: Using mouse genetics to study the developing spinal locomotor circuit - p. page_237 15. Chapter 12: Using mouse genetics to investigate supraspinal pathways of the brain important to locomotion - p. page_269 16. Chapter 13: Fundamental contributions of the cat model to the neural control of locomotion - p. page_315 17. Chapter 14: The micropig model of neurosurgery and spinal cord injury in experiments of motor control - p. page_349 18. Chapter 15: What lies beneath the brain: Neural circuits involved in human locomotion - p. page_385 19. Chapter 16: A tale of many models. Which one creates the best of times? - p. page_419 20. Index - p. page_427

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