Biological Inorganic Chemistry: A New Introduction to Molecular Structure and Function, Second Edition, provides a comprehensive discussion of the biochemical aspects of metals in living systems.
Beginning with an overview of metals and selected nonmetals in biology, the book then discusses the following concepts: basic coordination chemistry for biologists; structural and molecular biology for chemists; biological ligands for metal ions; intermediary metabolism and bioenergetics; and methods to study metals in biological systems.
The book also covers metal assimilation pathways; transport, storage, and homeostasis of metal ions; sodium and potassium channels and pumps; magnesium phosphate metabolism and photoreceptors; calcium and cellular signaling; the catalytic role of several classes of mononuclear zinc enzymes; the biological chemistry of iron; and copper chemistry and biochemistry. In addition, the book discusses nickel and cobalt enzymes; manganese chemistry and biochemistry; molybdenum, tungsten, vanadium, and chromium; non-metals in biology; biomineralization; metals in the brain; metals and neurodegeneration; metals in medicine and metals as drugs; and metals in the environment.
1. Cover Image 2. Table of Contents 3. Title 4. Copyright 5. Preface to the 2nd Edition 6. Chapter 1. An Overview of Metals and Selected Nonmetals in Biology 7. Chapter 2. Basic Coordination Chemistry for Biologists 8. Chapter 3. Structural and Molecular Biology for Chemists 9. Chapter 4. Biological Ligands for Metal Ions 10. Chapter 5. An Overview of Intermediary Metabolism and Bioenergetics 11. Chapter 6. Methods to Study Metals in Biological Systems 12. Chapter 7. Metal Assimilation Pathways 13. Chapter 8. Transport, Storage, and Homeostasis of Metal Ions 14. Chapter 9. Sodium and Potassium – Channels and Pumps 15. Chapter 10. Magnesium–Phosphate Metabolism and Photoreceptors 16. Chapter 11. Calcium – Cellular Signalling 17. Chapter 12. Zinc – Lewis Acid and Gene Regulator 18. Chapter 13. Iron 19. Chapter 14. Copper – Coping with Dioxygen 20. Chapter 15. Nickel and Cobalt 21. Chapter 16. Manganese – Oxygen Generation and Detoxification 22. Chapter 17. Molybdenum, Tungsten, Vanadium, and Chromium 23. Chapter 18. Non-metals in Biology 24. Chapter 19. Biomineralisation 25. Chapter 20. Metals in Brain 26. Chapter 21. Metals and Neurodegeneration 27. Chapter 22. Metals in Medicine and Metals as Drugs 28. Chapter 23. Metals in the Environment 29. Index
Biological Inorganic Chemistry: A New Introduction to Molecular Structure and Function, Second Edition, provides a comprehensive discussion of the biochemical aspects of metals in living systems.
Beginning with an overview of metals and selected nonmetals in biology, the book then discusses the following concepts: basic coordination chemistry for biologists; structural and molecular biology for chemists; biological ligands for metal ions; intermediary metabolism and bioenergetics; and methods to study metals in biological systems.
The book also covers metal assimilation pathways; transport, storage, and homeostasis of metal ions; sodium and potassium channels and pumps; magnesium phosphate metabolism and photoreceptors; calcium and cellular signaling; the catalytic role of several classes of mononuclear zinc enzymes; the biological chemistry of iron; and copper chemistry and biochemistry. In addition, the book discusses nickel and cobalt enzymes; manganese chemistry and biochemistry; molybdenum, tungsten, vanadium, and chromium; non-metals in biology; biomineralization; metals in the brain; metals and neurodegeneration; metals in medicine and metals as drugs; and metals in the environment.
1. Cover Image 2. Table of Contents 3. Title 4. Copyright 5. Preface to the 2nd Edition 6. Chapter 1. An Overview of Metals and Selected Nonmetals in Biology 7. Chapter 2. Basic Coordination Chemistry for Biologists 8. Chapter 3. Structural and Molecular Biology for Chemists 9. Chapter 4. Biological Ligands for Metal Ions 10. Chapter 5. An Overview of Intermediary Metabolism and Bioenergetics 11. Chapter 6. Methods to Study Metals in Biological Systems 12. Chapter 7. Metal Assimilation Pathways 13. Chapter 8. Transport, Storage, and Homeostasis of Metal Ions 14. Chapter 9. Sodium and Potassium – Channels and Pumps 15. Chapter 10. Magnesium–Phosphate Metabolism and Photoreceptors 16. Chapter 11. Calcium – Cellular Signalling 17. Chapter 12. Zinc – Lewis Acid and Gene Regulator 18. Chapter 13. Iron 19. Chapter 14. Copper – Coping with Dioxygen 20. Chapter 15. Nickel and Cobalt 21. Chapter 16. Manganese – Oxygen Generation and Detoxification 22. Chapter 17. Molybdenum, Tungsten, Vanadium, and Chromium 23. Chapter 18. Non-metals in Biology 24. Chapter 19. Biomineralisation 25. Chapter 20. Metals in Brain 26. Chapter 21. Metals and Neurodegeneration 27. Chapter 22. Metals in Medicine and Metals as Drugs 28. Chapter 23. Metals in the Environment 29. Index
