This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of breast pathology, it incorporates the most recent clinical, pathological, radiological, staging, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Breast is a one-stop reference for accurate, complete surgical pathology evaluation—ideal as a day-to-day reference or as a reliable training resource.
Includes a wide range of new information on breast pathology, including material specific to core needle biopsies, to help you identify, diagnose, and manage disease
Reflects updates to new tumor staging data in the American Joint Committee on Cancer (AJCC) 8th Edition and updated ASCO/CAP guidelines for interpreting HER2 assays
Brings you fully up to date with recent advances, including new molecular information for breast entities, new surgical techniques, more widely used multigene prognostic tests, and assays used to determine treatment, such as PD-L1 as a new immunotherapy biomarker for triple-negative breast cancer
Features new chapters covering gene expression profiling; immunotherapy; the differential diagnosis for common histologic patterns; solid papillary carcinoma; acinic cell carcinoma; and intraoperative consultations, including a video showing how to process specimens with radioactive seeds
Offers expert guidance on evaluation of postneoadjuvant resection specimens, sentinel lymph nodes, and extent of disease and multifocality
Contains thousands of extensively annotated images, including gross pathology photographs, histopathology photomicrographs with a wide range of immunohistochemical stains, fluorescent in situ hybridization, and full-color illustrations
Features a templated, highly formatted design; concise, bulleted text; diagnostic pearls; key facts in each chapter; and an extensive index for easy reference
Includes the enhanced eBook version, which allows you to search all text, figures, and references on a variety of devices
1. Chapter 56: Introduction: Prognostic and Predictive Factors - p. 401 2. Chapter 57: AJCC Breast Cancer Staging - p. 409 3. Chapter 58: Locally Advanced Breast Cancer - p. 417 4. ANATOMIC FACTORS - p. 421 5. Chapter 59: Locally Recurrent Carcinoma - p. 421 6. Chapter 60: Neoadjuvant Therapy - p. 427 7. Chapter 61: Histologic Grade - p. 437 8. Chapter 62: Lymph Node Metastases - p. 443 9. Chapter 63: Lymphovascular Invasion - p. 455 10. Chapter 64: Size and Multiple Foci - p. 463 11. MOLECULAR FACTORS - p. 467 12. Chapter 65: Hormone Receptors (ER/PR) - p. 467 13. Chapter 66: HER2 Evaluation - p. 477 14. Chapter 67: DNA Analysis - p. 491 15. Chapter 68: Circulating Tumor Cells and Circulating Tumor DNA - p. 495 16. Chapter 69: Immunotherapy: Markers - p. 499 17. Chapter 70: Expression Profiling, mRNA - p. 503 18. Chapter 71: Expression Profiling, Oncotype DX Assay - p. 509 19. Chapter 72: Expression Profiling, MammaPrint Assay - p. 513 20. Chapter 73: Expression Profiling, Prosigna (NanoString)/PAM50 - p. 515 21. Chapter 74: Expression Profiling, Protein - p. 517 22. Chapter 75: Expression Profiling, EndoPredict - p. 525 23. SECTION 8: STROMAL LESIONS - p. 527 24. Chapter 76: Fibroadenoma - p. 527 25. Chapter 77: Phyllodes Tumor - p. 537 26. Chapter 78: Pseudoangiomatous Stromal Hyperplasia - p. 547 27. Chapter 79: Myofibroblastoma - p. 551 28. Chapter 80: Lipoma and Angiolipoma - p. 559 29. Chapter 81: Diabetic Mastopathy/Lymphocytic Mastopathy - p. 563 30. Chapter 82: Granular Cell Tumor - p. 567 31. Chapter 83: Nodular Fasciitis - p. 573 32. Chapter 84: Fibromatosis - p. 579 33. Chapter 85: Hemangiomas - p. 587 34. Chapter 86: Papillary Endothelial Hyperplasia - p. 593 35. Chapter 87: Atypical Vascular Lesions of Skin - p. 595 36. Chapter 88: Angiosarcoma - p. 599 37. Chapter 89: Sarcomas - p. 609 38. SECTION 9: INFLAMMATORY LESIONS - p. 615 39. Chapter 90: Lactational Abscess - p. 615 40. Chapter 91: Nonlactational Abscess - p. 619 41. Chapter 92: Fat Necrosis - p. 627 42. Chapter 93: Duct Ectasia - p. 631 43. Chapter 94: Squamous Metaplasia of Lactiferous Ducts - p. 633 44. Chapter 95: Implant Pathology - p. 639 45. Chapter 96: Sarcoidosis - p. 647 46. Chapter 97: Amyloid of the Breast - p. 649 47. Chapter 98: Lupus Mastitis - p. 651 48. Chapter 99: IgG4-Related Sclerosing Mastitis - p. 653 49. SECTION 10: OTHER TYPES OF MALIGNANCIES - p. 657 50. Chapter 100: Metastases to Breast - p. 657 51. Chapter 101: Lymphoma - p. 665 52. SECTION 11: HEREDITARY BREAST DISEASE - p. 675 53. Chapter 102: Hereditary Breast Cancer - p. 675 54. Chapter 103: Germline Mutations Conferring Increased Risk of Breast Cancer: Tables - p. 685 55. Chapter 104: Breast/Ovarian Cancer Syndrome: BRCA1 - p. 687 56. Chapter 105: Breast/Ovarian Cancer Syndrome: BRCA2 - p. 693 57. Chapter 106: Li-Fraumeni Syndrome - p. 697 58. SECTION 12: UNUSUAL PRESENTATIONS OF BREAST LESIONS - p. 703 59. Chapter 107: Breast Carcinoma, Male - p. 703 60. Chapter 108: Iatrogenic Changes - p. 709 61. Index - p. 719
This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of breast pathology, it incorporates the most recent clinical, pathological, radiological, staging, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Breast is a one-stop reference for accurate, complete surgical pathology evaluation—ideal as a day-to-day reference or as a reliable training resource.
Includes a wide range of new information on breast pathology, including material specific to core needle biopsies, to help you identify, diagnose, and manage disease
Reflects updates to new tumor staging data in the American Joint Committee on Cancer (AJCC) 8th Edition and updated ASCO/CAP guidelines for interpreting HER2 assays
Brings you fully up to date with recent advances, including new molecular information for breast entities, new surgical techniques, more widely used multigene prognostic tests, and assays used to determine treatment, such as PD-L1 as a new immunotherapy biomarker for triple-negative breast cancer
Features new chapters covering gene expression profiling; immunotherapy; the differential diagnosis for common histologic patterns; solid papillary carcinoma; acinic cell carcinoma; and intraoperative consultations, including a video showing how to process specimens with radioactive seeds
Offers expert guidance on evaluation of postneoadjuvant resection specimens, sentinel lymph nodes, and extent of disease and multifocality
Contains thousands of extensively annotated images, including gross pathology photographs, histopathology photomicrographs with a wide range of immunohistochemical stains, fluorescent in situ hybridization, and full-color illustrations
Features a templated, highly formatted design; concise, bulleted text; diagnostic pearls; key facts in each chapter; and an extensive index for easy reference
Includes the enhanced eBook version, which allows you to search all text, figures, and references on a variety of devices
1. Chapter 56: Introduction: Prognostic and Predictive Factors - p. 401 2. Chapter 57: AJCC Breast Cancer Staging - p. 409 3. Chapter 58: Locally Advanced Breast Cancer - p. 417 4. ANATOMIC FACTORS - p. 421 5. Chapter 59: Locally Recurrent Carcinoma - p. 421 6. Chapter 60: Neoadjuvant Therapy - p. 427 7. Chapter 61: Histologic Grade - p. 437 8. Chapter 62: Lymph Node Metastases - p. 443 9. Chapter 63: Lymphovascular Invasion - p. 455 10. Chapter 64: Size and Multiple Foci - p. 463 11. MOLECULAR FACTORS - p. 467 12. Chapter 65: Hormone Receptors (ER/PR) - p. 467 13. Chapter 66: HER2 Evaluation - p. 477 14. Chapter 67: DNA Analysis - p. 491 15. Chapter 68: Circulating Tumor Cells and Circulating Tumor DNA - p. 495 16. Chapter 69: Immunotherapy: Markers - p. 499 17. Chapter 70: Expression Profiling, mRNA - p. 503 18. Chapter 71: Expression Profiling, Oncotype DX Assay - p. 509 19. Chapter 72: Expression Profiling, MammaPrint Assay - p. 513 20. Chapter 73: Expression Profiling, Prosigna (NanoString)/PAM50 - p. 515 21. Chapter 74: Expression Profiling, Protein - p. 517 22. Chapter 75: Expression Profiling, EndoPredict - p. 525 23. SECTION 8: STROMAL LESIONS - p. 527 24. Chapter 76: Fibroadenoma - p. 527 25. Chapter 77: Phyllodes Tumor - p. 537 26. Chapter 78: Pseudoangiomatous Stromal Hyperplasia - p. 547 27. Chapter 79: Myofibroblastoma - p. 551 28. Chapter 80: Lipoma and Angiolipoma - p. 559 29. Chapter 81: Diabetic Mastopathy/Lymphocytic Mastopathy - p. 563 30. Chapter 82: Granular Cell Tumor - p. 567 31. Chapter 83: Nodular Fasciitis - p. 573 32. Chapter 84: Fibromatosis - p. 579 33. Chapter 85: Hemangiomas - p. 587 34. Chapter 86: Papillary Endothelial Hyperplasia - p. 593 35. Chapter 87: Atypical Vascular Lesions of Skin - p. 595 36. Chapter 88: Angiosarcoma - p. 599 37. Chapter 89: Sarcomas - p. 609 38. SECTION 9: INFLAMMATORY LESIONS - p. 615 39. Chapter 90: Lactational Abscess - p. 615 40. Chapter 91: Nonlactational Abscess - p. 619 41. Chapter 92: Fat Necrosis - p. 627 42. Chapter 93: Duct Ectasia - p. 631 43. Chapter 94: Squamous Metaplasia of Lactiferous Ducts - p. 633 44. Chapter 95: Implant Pathology - p. 639 45. Chapter 96: Sarcoidosis - p. 647 46. Chapter 97: Amyloid of the Breast - p. 649 47. Chapter 98: Lupus Mastitis - p. 651 48. Chapter 99: IgG4-Related Sclerosing Mastitis - p. 653 49. SECTION 10: OTHER TYPES OF MALIGNANCIES - p. 657 50. Chapter 100: Metastases to Breast - p. 657 51. Chapter 101: Lymphoma - p. 665 52. SECTION 11: HEREDITARY BREAST DISEASE - p. 675 53. Chapter 102: Hereditary Breast Cancer - p. 675 54. Chapter 103: Germline Mutations Conferring Increased Risk of Breast Cancer: Tables - p. 685 55. Chapter 104: Breast/Ovarian Cancer Syndrome: BRCA1 - p. 687 56. Chapter 105: Breast/Ovarian Cancer Syndrome: BRCA2 - p. 693 57. Chapter 106: Li-Fraumeni Syndrome - p. 697 58. SECTION 12: UNUSUAL PRESENTATIONS OF BREAST LESIONS - p. 703 59. Chapter 107: Breast Carcinoma, Male - p. 703 60. Chapter 108: Iatrogenic Changes - p. 709 61. Index - p. 719
