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Part of the highly regarded Diagnostic Pathology series, this updated volume by Drs. Anthony Chang and Robert B. Colvin is an ideal point-of-care reference to guide you through the complex realm of transplant pathology. Concise, focused chapters, supported by tables, diagrams, radiographs, and photographs, provide essential information to keep you up to date with the impact of new viral infections, updates from the Banff Allograft Conference, new information on next-generation sequencing, and much more.

  • More than 20 experts present their collective knowledge to assist you with different aspects of transplant pathology, including rare issues such as the impact of new viral infections (e.g., the Zika virus on transplant patients who are immunosuppressed)
  • Packed with high-quality images that provide examples and potential pitfalls of diagnostic lesions that you are likely to encounter
  • Time-saving reference features include bulleted text, tables of diagnostic criteria, annotated images, and an extensive index
  • Thoroughly updated content keeps you current with all aspects of transplant immunology and pathology, guiding you expertly through diagnostic challenges such as donor disease, surgical complications, allograft rejection, drug toxicity, opportunistic infections, and/or recurrent or de novo diseases that can occur simultaneously or at different times
  • New Banff classifications are integrated into all chapters, covering pathology of all clinical organ transplants, including kidney, heart, lung, liver, pancreas, small bowel, and vascularized composite allografts as well as bone marrow allografts
  • New coverage includes next-generation sequencing, which is quickly becoming the standard for HLA testing, as well as new drugs that are in clinical trials for the treatment of antibody-mediated rejection
  • Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices

1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Dedication - p. iii 6. Contributing Authors - p. v 7. Preface - p. v 8. Acknowledgments - p. ix 9. Sections - p. xi 10. SECTION 1: IMMUNOLOGY - p. xiii 11. Chapter 1: Immune Response in Organ Transplantation - p. xiii 12. Chapter 2: Regulatory Immune Cells and Transplant Tolerance - p. 7 13. Chapter 3: NK Cells - p. 13 14. Chapter 4: Complement - p. 19 15. Chapter 5: Laboratory-Based Immune Monitoring in Organ Transplantation - p. 23 16. SECTION 2: HLA TESTING - p. 29 17. Chapter 6: Human Leukocyte Antigen System - p. 29 18. Chapter 7: Histocompatibility Testing - p. 33 19. Chapter 8: Transplantation and HLA - p. 35 20. Chapter 9: ABO Blood Group Antigens and Transplantation - p. 39 21. Chapter 10: Apheresis and Transplantation - p. 41 22. Chapter 11: HLA and Transfusion - p. 43 23. SECTION 3: IMMUNOSUPPRESSIVE DRUGS - p. 45 24. Chapter 12: Mechanism of Action of Immunosuppressive Drugs - p. 45 25. Chapter 13: Therapeutic Drug Monitoring in Transplant Patients - p. 49 26. Chapter 14: History of Immunosuppression Drugs in Transplantation - p. 53 27. SECTION 4: KIDNEY TRANSPLANTATION - p. 55 28. Chapter 15: History of Kidney Transplantation - p. 55 29. Chapter 16: Pathologic Classification of Renal Allograft Diseases - p. 59 30. Chapter 17: Evaluation of the End-Stage Kidney - p. 61 31. Chapter 18: Evaluation of Allograft Kidney - p. 67 32. Chapter 19: Evaluation of the Donor Kidney - p. 73 33. Chapter 20: Evaluation of Transplant Nephrectomy - p. 79 34. Chapter 21: Evaluation of Fibrosis - p. 85 35. Chapter 22: Protocol Biopsies - p. 89 36. Chapter 23: Accommodation - p. 93 37. Chapter 24: Tolerance - p. 95 38. SURGICAL COMPLICATIONS - p. 99 39. Chapter 25: Acute Allograft Ischemia - p. 99 40. Chapter 26: Urine Leak - p. 103 41. Chapter 27: Lymphocele - p. 105 42. Chapter 28: Renal Artery or Vein Thrombosis - p. 107 43. Chapter 29: Transplant Renal Artery Stenosis - p. 109 44. ALLOGRAFT REJECTION - p. 111 45. Chapter 30: Hyperacute Rejection - p. 111 46. Chapter 31: Acute T-Cell-Mediated Rejection - p. 115 47. Chapter 32: Chronic T-Cell-Mediated Rejection - p. 127 48. Chapter 33: Acute Antibody-Mediated Rejection - p. 131 49. Chapter 34: Chronic Antibody-Mediated Rejection - p. 139 50. RECURRENT DISEASES - p. 151 51. Chapter 35: Recurrent Diseases in the Allograft - p. 151 52. DE NOVO DISEASES - p. 159 53. Chapter 36: De Novo Focal Segmental Glomerulosclerosis - p. 159 54. Chapter 37: De Novo Membranous Glomerulonephritis - p. 161 55. Chapter 38: Anti-GBM Disease in Alport Syndrome - p. 165 56. Chapter 39: Hyperperfusion Injury - p. 167 57. Chapter 40: Engraftment Syndrome - p. 169 58. Chapter 41: Kidney Diseases in Nonrenal Transplant Recipients - p. 173 59. Chapter 42: Graft-vs.-Host Glomerulopathies - p. 177 60. DRUG TOXICITIES - p. 179 61. Chapter 43: Calcineurin Inhibitor Toxicity - p. 179 62. Chapter 44: mTOR Inhibitor Toxicity - p. 185 63. INFECTIONS - p. 187 64. Chapter 45: Acute Pyelonephritis - p. 187 65. Chapter 46: Polyomavirus Nephritis - p. 191 66. Chapter 47: Adenovirus, Kidney - p. 199 67. Chapter 48: Cytomegalovirus Infection - p. 203 68. Chapter 49: Histoplasmosis - p. 207 69. Chapter 50: Candidiasis - p. 209 70. Chapter 51: Cryptococcosis - p. 211 71. Chapter 52: Mucormycosis - p. 213 72. Chapter 53: Aspergillosis - p. 215 73. Chapter 54: Coccidioidomycosis - p. 217 74. Chapter 55: Paracoccidioidomycosis - p. 219 75. Chapter 56: Microsporidiosis - p. 221 76. Chapter 57: Tuberculosis - p. 223 77. Chapter 58: Malakoplakia - p. 225 78. Chapter 59: Nocardiosis - p. 229 79. SECTION 5: LIVER TRANSPLANTATION - p. 231 80. Chapter 60: Pathologic Classification of Liver Allograft Diseases - p. 231 81. Chapter 61: Gross Evaluation of Failed Native Liver - p. 235 82. Chapter 62: Evaluation of Failed Liver Allograft - p. 239 83. Chapter 63: Evaluation of the Donor Liver - p. 241 84. Chapter 64: History of Liver Transplantation - p. 245 85. POSTTRANSPLANT SURGICAL COMPLICATIONS - p. 247 86. Chapter 65: Preservation Injury - p. 247 87. Chapter 66: Hepatic Artery Thrombosis - p. 249 88. Chapter 67: Portal Vein Thrombosis - p. 251 89. Chapter 68: Bile Duct Stricture, Leak, Sludge, Biloma - p. 253 90. Chapter 69: Hepatic Venous Outflow Obstruction - p. 255 91. Chapter 70: Hyperperfusion Syndrome - p. 259 92. ALLOGRAFT REJECTION - p. 261 93. Chapter 71: T-Cell-Mediated Rejection, Liver - p. 261 94. Chapter 72: Antibody-Mediated Rejection, Liver - p. 265 95. Chapter 73: Chronic (Ductopenic) Rejection - p. 269 96. RECURRENT DISEASES IN LIVER ALLOGRAFT - p. 271 97. Chapter 74: Recurrent Hepatitis B Virus - p. 271 98. Chapter 75: Recurrent Hepatitis C Virus - p. 273 99. Chapter 76: Fibrosing Cholestatic HBV or HCV Hepatitis - p. 277 100. Chapter 77: Recurrent Autoimmune Hepatitis - p. 279 101. Chapter 78: Recurrent Primary Biliary Cholangitis - p. 281 102. Chapter 79: Recurrent Primary Sclerosing Cholangitis - p. 283 103. Chapter 80: Recurrent Fatty Liver Disease - p. 285 104. INFECTIONS - p. 287 105. Chapter 81: Cytomegalovirus - p. 287 106. Chapter 82: Herpes Simplex Virus - p. 289 107. Chapter 83: Adenovirus, Liver - p. 291 108. Chapter 84: Hepatitis E Virus - p. 293 109. Chapter 85: Epstein-Barr Virus, Liver - p. 295 110. Chapter 86: Fungal Infections, Liver - p. 299 111. LATE-GRAFT DYSFUNCTION - p. 301 112. Chapter 87: Plasma Cell-Rich Rejection - p. 301 113. Chapter 88: Graft-vs.-Host Disease, Liver - p. 303 114. SECTION 6: HEART TRANSPLANTATION - p. 305 115. Chapter 89: Pathologic Classification of Cardiac Allograft Diseases - p. 305 116. Chapter 90: Evaluation of Failed Native and Transplanted Heart - p. 309 117. Chapter 91: History of Heart Transplantation - p. 311 118. EVALUATION OF EXPLANTED HEART - p. 313 119. Chapter 92: Ischemic Heart Disease - p. 313 120. Chapter 93: Dilated Cardiomyopathy - p. 317 121. Chapter 94: Hypertrophic Cardiomyopathy - p. 321 122. Chapter 95: Congenital Heart Disease - p. 325 123. Chapter 96: Sarcoidosis, Heart - p. 329 124. Chapter 97: Arrhythmogenic Right Ventricular Cardiomyopathy - p. 331 125. Chapter 98: Other Causes of End-Stage Heart Disease - p. 335 126. ALLOGRAFT REJECTION - p. 341 127. Chapter 99: Acute Cellular Rejection, Heart - p. 341 128. Chapter 100: Antibody-Mediated Rejection, Heart - p. 345 129. Chapter 101: Chronic Allograft Vasculopathy, Heart - p. 347 130. NONINFECTIOUS LESIONS - p. 349 131. Chapter 102: Quilty Lesions - p. 349 132. Chapter 103: Site of Previous Biopsy - p. 351 133. INFECTIONS - p. 353 134. Chapter 104: Myocarditis - p. 353 135. SECTION 7: LUNG TRANSPLANTATION - p. 359 136. Chapter 105: Pathologic Classification of Lung Allograft Diseases - p. 359 137. Chapter 106: Examination of Native and Transplanted Lungs - p. 363 138. Chapter 107: History of Lung Transplantation - p. 365 139. EVALUATION OF FAILED NATIVE LUNG - p. 367 140. Chapter 108: Emphysema - p. 367 141. Chapter 109: Cystic Fibrosis - p. 369 142. Chapter 110: Idiopathic Pulmonary Fibrosis - p. 371 143. Chapter 111: Connective Tissue Disease-Associated Lung Disease - p. 373 144. Chapter 112: Sarcoidosis, Lung - p. 375 145. Chapter 113: Pulmonary Arterial Hypertension - p. 377 146. Chapter 114: Other Causes of End-Stage Lung Disease - p. 379 147. SURGICAL COMPLICATIONS - p. 383 148. Chapter 115: Surgical Aspects and Complications, Lung - p. 383 149. ALLOGRAFT REJECTION - p. 385 150. Chapter 116: Pathologic Classification of Rejection - p. 385 151. Chapter 117: Antibody-Mediated Rejection, Lung - p. 387 152. Chapter 118: Acute Cellular Rejection, Grade A - p. 389 153. Chapter 119: Acute Cellular Rejection, Grade B - p. 391 154. Chapter 120: Chronic Allograft Dysfunction, Lung - p. 393 155. NONINFECTIOUS LESIONS - p. 395 156. Chapter 121: Organizing Pneumonia - p. 395 157. Chapter 122: Microaspiration - p. 397 158. INFECTIONS - p. 399 159. Chapter 123: Bacterial Infections - p. 399 160. Chapter 124: Viral Infections - p. 401 161. Chapter 125: Fungal Infections, Lung - p. 405 162. SECTION 8: INTESTINAL TRANSPLANTATION - p. 409 163. Chapter 126: Pathologic Classification of Intestinal Allograft Diseases - p. 409 164. Chapter 127: Indications and Evaluation of Explant - p. 413 165. Chapter 128: Reperfusion Injury - p. 417 166. Chapter 129: History of Intestinal and Multivisceral Transplantation - p. 421 167. ALLOGRAFT REJECTION/IMMUNOLOGICAL INJURY - p. 423 168. Chapter 130: Acute Antibody-Mediated Rejection, Intestine - p. 423 169. Chapter 131: Acute Cellular Rejection, Intestine - p. 427 170. Chapter 132: Chronic Rejection, Intestine - p. 435 171. Chapter 133: Stomach Rejection - p. 439 172. Chapter 134: Colon Rejection - p. 443 173. Chapter 135: Graft-vs.-Host Disease, Intestine - p. 447 174. INFECTIONS - p. 451 175. Chapter 136: Bacterial and Fungal Infections - p. 451 176. Chapter 137: Adenovirus, Intestine - p. 455 177. Chapter 138: Rotavirus, Cytomegalovirus, and Herpes Simplex Virus - p. 459 178. Chapter 139: Epstein-Barr Virus, Intestine - p. 463 179. SECTION 9: PANCREAS TRANSPLANTATION - p. 469 180. Chapter 140: Pathologic Classification of Pancreas Allograft Diseases - p. 469 181. Chapter 141: Clinical Considerations in Pancreas Transplant Evaluation - p. 473 182. Chapter 142: History of Pancreas Transplantation - p. 479 183. SURGICAL COMPLICATIONS - p. 481 184. Chapter 143: Surgical Aspects and Complications, Pancreas - p. 481 185. ALLOGRAFT REJECTION - p. 487 186. Chapter 144: Acute Cellular Rejection, Pancreas - p. 487 187. Chapter 145: Antibody-Mediated Rejection, Pancreas - p. 491 188. Chapter 146: Chronic Allograft Rejection/Graft Sclerosis - p. 495 189. GRAFT DYSFUNCTION - p. 497 190. Chapter 147: Recurrent Diabetes Mellitus - p. 497 191. Chapter 148: Islet Cell Toxicity and Islet Amyloid Deposition - p. 501 192. INFECTIONS - p. 503 193. Chapter 149: Intraabdominal and Opportunistic Infections - p. 503 194. SECTION 10: VASCULARIZED COMPOSITE ALLOTRANSPLANTATION - p. 509 195. Chapter 150: History of Vascularized Composite Allotransplantation - p. 509 196. ALLOGRAFT REJECTION - p. 513 197. Chapter 151: Acute T-Cell- and Antibody-Mediated Rejection - p. 513 198. Chapter 152: Chronic Rejection - p. 521 199. SECTION 11: POSTTRANSPLANT NEOPLASTIC DISORDERS - p. 523 200. Chapter 153: Posttransplant Lymphoproliferative Disease - p. 523 201. INDEX - p. 535

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Part of the highly regarded Diagnostic Pathology series, this updated volume by Drs. Anthony Chang and Robert B. Colvin is an ideal point-of-care reference to guide you through the complex realm of transplant pathology. Concise, focused chapters, supported by tables, diagrams, radiographs, and photographs, provide essential information to keep you up to date with the impact of new viral infections, updates from the Banff Allograft Conference, new information on next-generation sequencing, and much more.

  • More than 20 experts present their collective knowledge to assist you with different aspects of transplant pathology, including rare issues such as the impact of new viral infections (e.g., the Zika virus on transplant patients who are immunosuppressed)
  • Packed with high-quality images that provide examples and potential pitfalls of diagnostic lesions that you are likely to encounter
  • Time-saving reference features include bulleted text, tables of diagnostic criteria, annotated images, and an extensive index
  • Thoroughly updated content keeps you current with all aspects of transplant immunology and pathology, guiding you expertly through diagnostic challenges such as donor disease, surgical complications, allograft rejection, drug toxicity, opportunistic infections, and/or recurrent or de novo diseases that can occur simultaneously or at different times
  • New Banff classifications are integrated into all chapters, covering pathology of all clinical organ transplants, including kidney, heart, lung, liver, pancreas, small bowel, and vascularized composite allografts as well as bone marrow allografts
  • New coverage includes next-generation sequencing, which is quickly becoming the standard for HLA testing, as well as new drugs that are in clinical trials for the treatment of antibody-mediated rejection
  • Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices

1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Dedication - p. iii 6. Contributing Authors - p. v 7. Preface - p. v 8. Acknowledgments - p. ix 9. Sections - p. xi 10. SECTION 1: IMMUNOLOGY - p. xiii 11. Chapter 1: Immune Response in Organ Transplantation - p. xiii 12. Chapter 2: Regulatory Immune Cells and Transplant Tolerance - p. 7 13. Chapter 3: NK Cells - p. 13 14. Chapter 4: Complement - p. 19 15. Chapter 5: Laboratory-Based Immune Monitoring in Organ Transplantation - p. 23 16. SECTION 2: HLA TESTING - p. 29 17. Chapter 6: Human Leukocyte Antigen System - p. 29 18. Chapter 7: Histocompatibility Testing - p. 33 19. Chapter 8: Transplantation and HLA - p. 35 20. Chapter 9: ABO Blood Group Antigens and Transplantation - p. 39 21. Chapter 10: Apheresis and Transplantation - p. 41 22. Chapter 11: HLA and Transfusion - p. 43 23. SECTION 3: IMMUNOSUPPRESSIVE DRUGS - p. 45 24. Chapter 12: Mechanism of Action of Immunosuppressive Drugs - p. 45 25. Chapter 13: Therapeutic Drug Monitoring in Transplant Patients - p. 49 26. Chapter 14: History of Immunosuppression Drugs in Transplantation - p. 53 27. SECTION 4: KIDNEY TRANSPLANTATION - p. 55 28. Chapter 15: History of Kidney Transplantation - p. 55 29. Chapter 16: Pathologic Classification of Renal Allograft Diseases - p. 59 30. Chapter 17: Evaluation of the End-Stage Kidney - p. 61 31. Chapter 18: Evaluation of Allograft Kidney - p. 67 32. Chapter 19: Evaluation of the Donor Kidney - p. 73 33. Chapter 20: Evaluation of Transplant Nephrectomy - p. 79 34. Chapter 21: Evaluation of Fibrosis - p. 85 35. Chapter 22: Protocol Biopsies - p. 89 36. Chapter 23: Accommodation - p. 93 37. Chapter 24: Tolerance - p. 95 38. SURGICAL COMPLICATIONS - p. 99 39. Chapter 25: Acute Allograft Ischemia - p. 99 40. Chapter 26: Urine Leak - p. 103 41. Chapter 27: Lymphocele - p. 105 42. Chapter 28: Renal Artery or Vein Thrombosis - p. 107 43. Chapter 29: Transplant Renal Artery Stenosis - p. 109 44. ALLOGRAFT REJECTION - p. 111 45. Chapter 30: Hyperacute Rejection - p. 111 46. Chapter 31: Acute T-Cell-Mediated Rejection - p. 115 47. Chapter 32: Chronic T-Cell-Mediated Rejection - p. 127 48. Chapter 33: Acute Antibody-Mediated Rejection - p. 131 49. Chapter 34: Chronic Antibody-Mediated Rejection - p. 139 50. RECURRENT DISEASES - p. 151 51. Chapter 35: Recurrent Diseases in the Allograft - p. 151 52. DE NOVO DISEASES - p. 159 53. Chapter 36: De Novo Focal Segmental Glomerulosclerosis - p. 159 54. Chapter 37: De Novo Membranous Glomerulonephritis - p. 161 55. Chapter 38: Anti-GBM Disease in Alport Syndrome - p. 165 56. Chapter 39: Hyperperfusion Injury - p. 167 57. Chapter 40: Engraftment Syndrome - p. 169 58. Chapter 41: Kidney Diseases in Nonrenal Transplant Recipients - p. 173 59. Chapter 42: Graft-vs.-Host Glomerulopathies - p. 177 60. DRUG TOXICITIES - p. 179 61. Chapter 43: Calcineurin Inhibitor Toxicity - p. 179 62. Chapter 44: mTOR Inhibitor Toxicity - p. 185 63. INFECTIONS - p. 187 64. Chapter 45: Acute Pyelonephritis - p. 187 65. Chapter 46: Polyomavirus Nephritis - p. 191 66. Chapter 47: Adenovirus, Kidney - p. 199 67. Chapter 48: Cytomegalovirus Infection - p. 203 68. Chapter 49: Histoplasmosis - p. 207 69. Chapter 50: Candidiasis - p. 209 70. Chapter 51: Cryptococcosis - p. 211 71. Chapter 52: Mucormycosis - p. 213 72. Chapter 53: Aspergillosis - p. 215 73. Chapter 54: Coccidioidomycosis - p. 217 74. Chapter 55: Paracoccidioidomycosis - p. 219 75. Chapter 56: Microsporidiosis - p. 221 76. Chapter 57: Tuberculosis - p. 223 77. Chapter 58: Malakoplakia - p. 225 78. Chapter 59: Nocardiosis - p. 229 79. SECTION 5: LIVER TRANSPLANTATION - p. 231 80. Chapter 60: Pathologic Classification of Liver Allograft Diseases - p. 231 81. Chapter 61: Gross Evaluation of Failed Native Liver - p. 235 82. Chapter 62: Evaluation of Failed Liver Allograft - p. 239 83. Chapter 63: Evaluation of the Donor Liver - p. 241 84. Chapter 64: History of Liver Transplantation - p. 245 85. POSTTRANSPLANT SURGICAL COMPLICATIONS - p. 247 86. Chapter 65: Preservation Injury - p. 247 87. Chapter 66: Hepatic Artery Thrombosis - p. 249 88. Chapter 67: Portal Vein Thrombosis - p. 251 89. Chapter 68: Bile Duct Stricture, Leak, Sludge, Biloma - p. 253 90. Chapter 69: Hepatic Venous Outflow Obstruction - p. 255 91. Chapter 70: Hyperperfusion Syndrome - p. 259 92. ALLOGRAFT REJECTION - p. 261 93. Chapter 71: T-Cell-Mediated Rejection, Liver - p. 261 94. Chapter 72: Antibody-Mediated Rejection, Liver - p. 265 95. Chapter 73: Chronic (Ductopenic) Rejection - p. 269 96. RECURRENT DISEASES IN LIVER ALLOGRAFT - p. 271 97. Chapter 74: Recurrent Hepatitis B Virus - p. 271 98. Chapter 75: Recurrent Hepatitis C Virus - p. 273 99. Chapter 76: Fibrosing Cholestatic HBV or HCV Hepatitis - p. 277 100. Chapter 77: Recurrent Autoimmune Hepatitis - p. 279 101. Chapter 78: Recurrent Primary Biliary Cholangitis - p. 281 102. Chapter 79: Recurrent Primary Sclerosing Cholangitis - p. 283 103. Chapter 80: Recurrent Fatty Liver Disease - p. 285 104. INFECTIONS - p. 287 105. Chapter 81: Cytomegalovirus - p. 287 106. Chapter 82: Herpes Simplex Virus - p. 289 107. Chapter 83: Adenovirus, Liver - p. 291 108. Chapter 84: Hepatitis E Virus - p. 293 109. Chapter 85: Epstein-Barr Virus, Liver - p. 295 110. Chapter 86: Fungal Infections, Liver - p. 299 111. LATE-GRAFT DYSFUNCTION - p. 301 112. Chapter 87: Plasma Cell-Rich Rejection - p. 301 113. Chapter 88: Graft-vs.-Host Disease, Liver - p. 303 114. SECTION 6: HEART TRANSPLANTATION - p. 305 115. Chapter 89: Pathologic Classification of Cardiac Allograft Diseases - p. 305 116. Chapter 90: Evaluation of Failed Native and Transplanted Heart - p. 309 117. Chapter 91: History of Heart Transplantation - p. 311 118. EVALUATION OF EXPLANTED HEART - p. 313 119. Chapter 92: Ischemic Heart Disease - p. 313 120. Chapter 93: Dilated Cardiomyopathy - p. 317 121. Chapter 94: Hypertrophic Cardiomyopathy - p. 321 122. Chapter 95: Congenital Heart Disease - p. 325 123. Chapter 96: Sarcoidosis, Heart - p. 329 124. Chapter 97: Arrhythmogenic Right Ventricular Cardiomyopathy - p. 331 125. Chapter 98: Other Causes of End-Stage Heart Disease - p. 335 126. ALLOGRAFT REJECTION - p. 341 127. Chapter 99: Acute Cellular Rejection, Heart - p. 341 128. Chapter 100: Antibody-Mediated Rejection, Heart - p. 345 129. Chapter 101: Chronic Allograft Vasculopathy, Heart - p. 347 130. NONINFECTIOUS LESIONS - p. 349 131. Chapter 102: Quilty Lesions - p. 349 132. Chapter 103: Site of Previous Biopsy - p. 351 133. INFECTIONS - p. 353 134. Chapter 104: Myocarditis - p. 353 135. SECTION 7: LUNG TRANSPLANTATION - p. 359 136. Chapter 105: Pathologic Classification of Lung Allograft Diseases - p. 359 137. Chapter 106: Examination of Native and Transplanted Lungs - p. 363 138. Chapter 107: History of Lung Transplantation - p. 365 139. EVALUATION OF FAILED NATIVE LUNG - p. 367 140. Chapter 108: Emphysema - p. 367 141. Chapter 109: Cystic Fibrosis - p. 369 142. Chapter 110: Idiopathic Pulmonary Fibrosis - p. 371 143. Chapter 111: Connective Tissue Disease-Associated Lung Disease - p. 373 144. Chapter 112: Sarcoidosis, Lung - p. 375 145. Chapter 113: Pulmonary Arterial Hypertension - p. 377 146. Chapter 114: Other Causes of End-Stage Lung Disease - p. 379 147. SURGICAL COMPLICATIONS - p. 383 148. Chapter 115: Surgical Aspects and Complications, Lung - p. 383 149. ALLOGRAFT REJECTION - p. 385 150. Chapter 116: Pathologic Classification of Rejection - p. 385 151. Chapter 117: Antibody-Mediated Rejection, Lung - p. 387 152. Chapter 118: Acute Cellular Rejection, Grade A - p. 389 153. Chapter 119: Acute Cellular Rejection, Grade B - p. 391 154. Chapter 120: Chronic Allograft Dysfunction, Lung - p. 393 155. NONINFECTIOUS LESIONS - p. 395 156. Chapter 121: Organizing Pneumonia - p. 395 157. Chapter 122: Microaspiration - p. 397 158. INFECTIONS - p. 399 159. Chapter 123: Bacterial Infections - p. 399 160. Chapter 124: Viral Infections - p. 401 161. Chapter 125: Fungal Infections, Lung - p. 405 162. SECTION 8: INTESTINAL TRANSPLANTATION - p. 409 163. Chapter 126: Pathologic Classification of Intestinal Allograft Diseases - p. 409 164. Chapter 127: Indications and Evaluation of Explant - p. 413 165. Chapter 128: Reperfusion Injury - p. 417 166. Chapter 129: History of Intestinal and Multivisceral Transplantation - p. 421 167. ALLOGRAFT REJECTION/IMMUNOLOGICAL INJURY - p. 423 168. Chapter 130: Acute Antibody-Mediated Rejection, Intestine - p. 423 169. Chapter 131: Acute Cellular Rejection, Intestine - p. 427 170. Chapter 132: Chronic Rejection, Intestine - p. 435 171. Chapter 133: Stomach Rejection - p. 439 172. Chapter 134: Colon Rejection - p. 443 173. Chapter 135: Graft-vs.-Host Disease, Intestine - p. 447 174. INFECTIONS - p. 451 175. Chapter 136: Bacterial and Fungal Infections - p. 451 176. Chapter 137: Adenovirus, Intestine - p. 455 177. Chapter 138: Rotavirus, Cytomegalovirus, and Herpes Simplex Virus - p. 459 178. Chapter 139: Epstein-Barr Virus, Intestine - p. 463 179. SECTION 9: PANCREAS TRANSPLANTATION - p. 469 180. Chapter 140: Pathologic Classification of Pancreas Allograft Diseases - p. 469 181. Chapter 141: Clinical Considerations in Pancreas Transplant Evaluation - p. 473 182. Chapter 142: History of Pancreas Transplantation - p. 479 183. SURGICAL COMPLICATIONS - p. 481 184. Chapter 143: Surgical Aspects and Complications, Pancreas - p. 481 185. ALLOGRAFT REJECTION - p. 487 186. Chapter 144: Acute Cellular Rejection, Pancreas - p. 487 187. Chapter 145: Antibody-Mediated Rejection, Pancreas - p. 491 188. Chapter 146: Chronic Allograft Rejection/Graft Sclerosis - p. 495 189. GRAFT DYSFUNCTION - p. 497 190. Chapter 147: Recurrent Diabetes Mellitus - p. 497 191. Chapter 148: Islet Cell Toxicity and Islet Amyloid Deposition - p. 501 192. INFECTIONS - p. 503 193. Chapter 149: Intraabdominal and Opportunistic Infections - p. 503 194. SECTION 10: VASCULARIZED COMPOSITE ALLOTRANSPLANTATION - p. 509 195. Chapter 150: History of Vascularized Composite Allotransplantation - p. 509 196. ALLOGRAFT REJECTION - p. 513 197. Chapter 151: Acute T-Cell- and Antibody-Mediated Rejection - p. 513 198. Chapter 152: Chronic Rejection - p. 521 199. SECTION 11: POSTTRANSPLANT NEOPLASTIC DISORDERS - p. 523 200. Chapter 153: Posttransplant Lymphoproliferative Disease - p. 523 201. INDEX - p. 535

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