Imaging Neuroinflammation provides an overview of the molecular and cellular basis of inflammation and its effects on neuroanatomy, reviews state-of-the-art imaging tools available to measure neuroinflammation, and describes the application of those tools to both preclinical animal disease models and human disease.This book is an authoritative reference on imaging neuroinflammation, MRI, neuroinflammation, MR Spectroscopy of inflammation, Iron imaging in inflammation, and more.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Series Page - p. iii 5. Copyright - p. iii 6. List of contributors - p. iii 7. Preface - p. xi 8. Part 1 - p. xii 9. Part 1 Overview - p. xii 10. Chapter 1: Molecular and tissue basis of neuroinflammation in health and disease - p. 3 11. Part 2 - p. 27 12. Part 2 Imaging approaches to inflammation - p. 27 13. Chapter 2: Sensitivity and specificity of diffusion MRI to neuroinflammatory processes - p. 31 14. Chapter 3: Iron imaging in neuroinflammation - p. 51 15. Chapter 4: MRS in neuroinflammation - p. 79 16. Chapter 5: Magnetization transfer and chemical exchange saturation transfer in neuroinflammation - p. 117 17. Chapter 6: Gadolinium-based imaging of the blood brain barrier and brain waste clearance pathways - p. 143 18. Chapter 7: Magnetic particle imaging - p. 173 19. Chapter 8: Positron emission tomography imaging of neuroinflammation - p. 201 20. Part 3 - p. 257 21. Part 3 Animal models - p. 257 22. Chapter 9: The use of animal models of neuroinflammation for imaging studies - p. 261 23. Part 4 - p. 276 24. Part 4 Human inflammation-based diseases - p. 276 25. Chapter 10: Stroke - p. 279 26. Chapter 11: Central nervous system vasculitis - p. 305 27. Chapter 12: Dementia - p. 321 28. Chapter 13: Parkinson's disease - p. 337 29. Chapter 14: Amyotrophic lateral sclerosis - p. 363 30. Chapter 15: Multiple sclerosis - p. 387 31. Chapter 16: Pediatric leukodystrophies - p. 405 32. Chapter 17: Lupus - p. 434 33. Chapter 18: Autoimmune encephalitis - p. 448 34. Chapter 19: Schizophrenia spectrum disorders - p. 469 35. Index - p. 487
Imaging Neuroinflammation provides an overview of the molecular and cellular basis of inflammation and its effects on neuroanatomy, reviews state-of-the-art imaging tools available to measure neuroinflammation, and describes the application of those tools to both preclinical animal disease models and human disease.This book is an authoritative reference on imaging neuroinflammation, MRI, neuroinflammation, MR Spectroscopy of inflammation, Iron imaging in inflammation, and more.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Series Page - p. iii 5. Copyright - p. iii 6. List of contributors - p. iii 7. Preface - p. xi 8. Part 1 - p. xii 9. Part 1 Overview - p. xii 10. Chapter 1: Molecular and tissue basis of neuroinflammation in health and disease - p. 3 11. Part 2 - p. 27 12. Part 2 Imaging approaches to inflammation - p. 27 13. Chapter 2: Sensitivity and specificity of diffusion MRI to neuroinflammatory processes - p. 31 14. Chapter 3: Iron imaging in neuroinflammation - p. 51 15. Chapter 4: MRS in neuroinflammation - p. 79 16. Chapter 5: Magnetization transfer and chemical exchange saturation transfer in neuroinflammation - p. 117 17. Chapter 6: Gadolinium-based imaging of the blood brain barrier and brain waste clearance pathways - p. 143 18. Chapter 7: Magnetic particle imaging - p. 173 19. Chapter 8: Positron emission tomography imaging of neuroinflammation - p. 201 20. Part 3 - p. 257 21. Part 3 Animal models - p. 257 22. Chapter 9: The use of animal models of neuroinflammation for imaging studies - p. 261 23. Part 4 - p. 276 24. Part 4 Human inflammation-based diseases - p. 276 25. Chapter 10: Stroke - p. 279 26. Chapter 11: Central nervous system vasculitis - p. 305 27. Chapter 12: Dementia - p. 321 28. Chapter 13: Parkinson's disease - p. 337 29. Chapter 14: Amyotrophic lateral sclerosis - p. 363 30. Chapter 15: Multiple sclerosis - p. 387 31. Chapter 16: Pediatric leukodystrophies - p. 405 32. Chapter 17: Lupus - p. 434 33. Chapter 18: Autoimmune encephalitis - p. 448 34. Chapter 19: Schizophrenia spectrum disorders - p. 469 35. Index - p. 487