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This issue of Sleep Medicine Clinics is edited by Drs. Brown and Shahrokh Javaheri and focuses on Advanced PAP Therapies and Non-invasive Ventilation. Article topics include: Current Positive Airway Pressure Device Technology: What’s in the “black box?”; Testing the Performance of Positive Airway Pressure Generators: From Bench to Bedside; Treatment of Obstructive Sleep Apnea: Choosing the Best PAP Device; Treatment of Obstructive Sleep Apnea: Choosing the Best Interface; Treatment of Obstructive Sleep Apnea: Achieving Adherence and Dealing with Complications; Treatment of Hyperventilatory Central Sleep Apnea: Idiopathic, CHF, Cerebrovascular Disease, and High Altitude; Disordered Breathing Due to Chronic Opioid Use: Diverse Manifestations and Their Management; Obesity Hypoventilation Syndrome: Choosing the Appropriate Treatment for a Heterogeneous Disorder; Positive Airway Pressure Treatment in the Patient with Ventilatory Failure due to Neuromuscular Disease; Non-invasive Ventilation in Acute Ventilatory Failure; Domiciliary Non-invasive Ventilation for Chronic Ventilatory Failure; The Future of Positive Airway Pressure Technology.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. CME Accreditation Page - p. iii 6. Forthcoming Issues - p. v 7. Contributors - p. vii 8. Preface - p. xv 9. Positive Airway Pressure Device Technology Past and Present: What’s in the “Black Box”? - p. 501 10. Testing the Performance of Positive Airway Pressure Generators: From Bench to Bedside - p. 517 11. Treatment of Obstructive Sleep Apnea: Choosing the Best Positive Airway Pressure Device - p. 529 12. Treatment of Obstructive Sleep Apnea: Choosing the Best Interface - p. 543 13. Treatment of Obstructive Sleep Apnea: Achieving Adherence to Positive Airway Pressure Treatment and Dealing with Complications - p. 551 14. Positive Airway Pressure Therapy for Hyperventilatory Central Sleep Apnea: Idiopathic, Heart Failure, Cerebrovascular Disease, and High Altitude - p. 565 15. Sleep Disordered Breathing Caused by Chronic Opioid Use: Diverse Manifestations and Their Management - p. 573 16. Obesity Hypoventilation Syndrome: Choosing the Appropriate Treatment of a Heterogeneous Disorder - p. 587 17. Noninvasive Mechanical Ventilation in Acute Ventilatory Failure: Rationale and Current Applications - p. 597 18. Noninvasive Positive Pressure Ventilatory Support Begins During Sleep - p. 607 19. Future of Positive Airway Pressure Technology - p. 617

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This issue of Sleep Medicine Clinics is edited by Drs. Brown and Shahrokh Javaheri and focuses on Advanced PAP Therapies and Non-invasive Ventilation. Article topics include: Current Positive Airway Pressure Device Technology: What’s in the “black box?”; Testing the Performance of Positive Airway Pressure Generators: From Bench to Bedside; Treatment of Obstructive Sleep Apnea: Choosing the Best PAP Device; Treatment of Obstructive Sleep Apnea: Choosing the Best Interface; Treatment of Obstructive Sleep Apnea: Achieving Adherence and Dealing with Complications; Treatment of Hyperventilatory Central Sleep Apnea: Idiopathic, CHF, Cerebrovascular Disease, and High Altitude; Disordered Breathing Due to Chronic Opioid Use: Diverse Manifestations and Their Management; Obesity Hypoventilation Syndrome: Choosing the Appropriate Treatment for a Heterogeneous Disorder; Positive Airway Pressure Treatment in the Patient with Ventilatory Failure due to Neuromuscular Disease; Non-invasive Ventilation in Acute Ventilatory Failure; Domiciliary Non-invasive Ventilation for Chronic Ventilatory Failure; The Future of Positive Airway Pressure Technology.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. CME Accreditation Page - p. iii 6. Forthcoming Issues - p. v 7. Contributors - p. vii 8. Preface - p. xv 9. Positive Airway Pressure Device Technology Past and Present: What’s in the “Black Box”? - p. 501 10. Testing the Performance of Positive Airway Pressure Generators: From Bench to Bedside - p. 517 11. Treatment of Obstructive Sleep Apnea: Choosing the Best Positive Airway Pressure Device - p. 529 12. Treatment of Obstructive Sleep Apnea: Choosing the Best Interface - p. 543 13. Treatment of Obstructive Sleep Apnea: Achieving Adherence to Positive Airway Pressure Treatment and Dealing with Complications - p. 551 14. Positive Airway Pressure Therapy for Hyperventilatory Central Sleep Apnea: Idiopathic, Heart Failure, Cerebrovascular Disease, and High Altitude - p. 565 15. Sleep Disordered Breathing Caused by Chronic Opioid Use: Diverse Manifestations and Their Management - p. 573 16. Obesity Hypoventilation Syndrome: Choosing the Appropriate Treatment of a Heterogeneous Disorder - p. 587 17. Noninvasive Mechanical Ventilation in Acute Ventilatory Failure: Rationale and Current Applications - p. 597 18. Noninvasive Positive Pressure Ventilatory Support Begins During Sleep - p. 607 19. Future of Positive Airway Pressure Technology - p. 617

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