Within this one volume both basic science and clinical immunology are demystified for the medical and other health sciences student. The basic immunological processes are described first, with a level of detail restricted to what is appropriate for medical (and similar) curricula. In the second part of the book, immunological mechanisms behind major diseases of the various body systems are explained. Throughout the text clinical details are highlighted and more in-depth material is differentiated from the main text.
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Preface to the second edition - p. iii 6. Preface to the first edition - p. v 7. Symbols used in the diagrams - p. vi 8. List of Tables - p. viii 9. Chapter 1: Anatomy and cells of the immune system - p. viii 10. Chapter 2: Innate immunity I: physical and humoral protection - p. 9 11. Chapter 3: Innate immunity II: cellular mechanisms - p. 22 12. Chapter 4: Acquired immunity: antigen receptors - p. 34 13. Chapter 5: The human leukocyte antigens - p. 53 14. Chapter 6: Cellular immune responses I: dendritic cells, macrophages and B lymphocytes - p. 70 15. Chapter 7: Cellular immune responses II: T lymphocytes, antigen presentation and natural killer cells - p. 85 16. Chapter 8: The immune response to microbes: an overview - p. 114 17. Chapter 9: Tolerance and mechanisms of autoimmunity - p. 120 18. Chapter 10: Hypersensitivity reactions and clinical allergy - p. 132 19. Chapter 11: Transplantation - p. 150 20. Chapter 12: Rheumatic diseases - p. 165 21. Chapter 13: Endocrine autoimmune disease - p. 188 22. Chapter 14: Liver diseases - p. 202 23. Chapter 15: Gastrointestinal diseases - p. 210 24. Chapter 16: Immune-mediated nephritis and vasculitis - p. 218 25. Chapter 17: Immune-mediated skin disease - p. 237 26. Chapter 18: Immune-mediated diseases of the nervous system and eye - p. 248 27. Chapter 19: Immunodeficiency - p. 263 28. Chapter 20: Human immunodeficiency virus and AIDS - p. 281 29. Chapter 21: Immunological manifestations of haematological disease - p. 292 30. Chapter 22: Immune-based therapies - p. 305 31. Chapter 23: Immunisation - p. 322 32. Appendices - p. 332 33. Commonly encountered CD molecules - p. 332 34. Major cytokines, cells releasing them, targets and functions - p. 341 35. List of class II human leukocyte antigen alleles - p. 345 36. Abbreviations used for amino acids - p. 346 37. Index - p. 347
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Within this one volume both basic science and clinical immunology are demystified for the medical and other health sciences student. The basic immunological processes are described first, with a level of detail restricted to what is appropriate for medical (and similar) curricula. In the second part of the book, immunological mechanisms behind major diseases of the various body systems are explained. Throughout the text clinical details are highlighted and more in-depth material is differentiated from the main text.
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Preface to the second edition - p. iii 6. Preface to the first edition - p. v 7. Symbols used in the diagrams - p. vi 8. List of Tables - p. viii 9. Chapter 1: Anatomy and cells of the immune system - p. viii 10. Chapter 2: Innate immunity I: physical and humoral protection - p. 9 11. Chapter 3: Innate immunity II: cellular mechanisms - p. 22 12. Chapter 4: Acquired immunity: antigen receptors - p. 34 13. Chapter 5: The human leukocyte antigens - p. 53 14. Chapter 6: Cellular immune responses I: dendritic cells, macrophages and B lymphocytes - p. 70 15. Chapter 7: Cellular immune responses II: T lymphocytes, antigen presentation and natural killer cells - p. 85 16. Chapter 8: The immune response to microbes: an overview - p. 114 17. Chapter 9: Tolerance and mechanisms of autoimmunity - p. 120 18. Chapter 10: Hypersensitivity reactions and clinical allergy - p. 132 19. Chapter 11: Transplantation - p. 150 20. Chapter 12: Rheumatic diseases - p. 165 21. Chapter 13: Endocrine autoimmune disease - p. 188 22. Chapter 14: Liver diseases - p. 202 23. Chapter 15: Gastrointestinal diseases - p. 210 24. Chapter 16: Immune-mediated nephritis and vasculitis - p. 218 25. Chapter 17: Immune-mediated skin disease - p. 237 26. Chapter 18: Immune-mediated diseases of the nervous system and eye - p. 248 27. Chapter 19: Immunodeficiency - p. 263 28. Chapter 20: Human immunodeficiency virus and AIDS - p. 281 29. Chapter 21: Immunological manifestations of haematological disease - p. 292 30. Chapter 22: Immune-based therapies - p. 305 31. Chapter 23: Immunisation - p. 322 32. Appendices - p. 332 33. Commonly encountered CD molecules - p. 332 34. Major cytokines, cells releasing them, targets and functions - p. 341 35. List of class II human leukocyte antigen alleles - p. 345 36. Abbreviations used for amino acids - p. 346 37. Index - p. 347
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