This issue of Hematology/Oncology Clinics of North America, guest edited by Dr. Robert Brodsky, is devoted to Complement-mediated Hemolytic Anemias. Articles in this outstanding issue include: Complement: An overview for the clinician; Warm autoimmune hemolytic anemia; Cold Agglutinin Disease; ABO incompatible blood transfusions; Paroxysmal cold hemoglobinuria; Paroxysmal nocturnal hemoglobinuria; Congenital CD59 deficiency; Atypical Hemolytic Uremic Syndrome (HUS); Typical Hemolytic Uremic Syndrome (HUS); Thrombotic thrombocytopenic purpura; and Pharmacologic complement inhibitors.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Copyright - p. 4 5. Contributors - p. 5 6. Forthcoming Issues - p. 8 7. Preface: Complement in Health and Disease - p. 9 8. Complement - p. 10 9. Hemolysis from ABO Incompatibility - p. 19 10. Warm Autoimmune Hemolytic Anemia - p. 26 11. Cold Agglutinin-Mediated Autoimmune Hemolytic Anemia - p. 30 12. Paroxysmal Cold Hemoglobinuria - p. 40 13. Paroxysmal Nocturnal Hemoglobinuria - p. 44 14. Congenital CD59 Deficiency - p. 53 15. Ultralarge Von Willebrand Factor–Induced Platelet Clumping and Activation of the Alternative Complement Pathway in Thrombotic Thrombocytopenic Purpura and the Hemolytic-Uremic Syndromes - p. 59 16. Shiga Toxin Associated Hemolytic Uremic Syndrome - p. 67 17. Thrombotic Microangiopathy - p. 74 18. Current and Future Pharmacologic Complement Inhibitors - p. 85 19. Index - p. 97
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This issue of Hematology/Oncology Clinics of North America, guest edited by Dr. Robert Brodsky, is devoted to Complement-mediated Hemolytic Anemias. Articles in this outstanding issue include: Complement: An overview for the clinician; Warm autoimmune hemolytic anemia; Cold Agglutinin Disease; ABO incompatible blood transfusions; Paroxysmal cold hemoglobinuria; Paroxysmal nocturnal hemoglobinuria; Congenital CD59 deficiency; Atypical Hemolytic Uremic Syndrome (HUS); Typical Hemolytic Uremic Syndrome (HUS); Thrombotic thrombocytopenic purpura; and Pharmacologic complement inhibitors.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Copyright - p. 4 5. Contributors - p. 5 6. Forthcoming Issues - p. 8 7. Preface: Complement in Health and Disease - p. 9 8. Complement - p. 10 9. Hemolysis from ABO Incompatibility - p. 19 10. Warm Autoimmune Hemolytic Anemia - p. 26 11. Cold Agglutinin-Mediated Autoimmune Hemolytic Anemia - p. 30 12. Paroxysmal Cold Hemoglobinuria - p. 40 13. Paroxysmal Nocturnal Hemoglobinuria - p. 44 14. Congenital CD59 Deficiency - p. 53 15. Ultralarge Von Willebrand Factor–Induced Platelet Clumping and Activation of the Alternative Complement Pathway in Thrombotic Thrombocytopenic Purpura and the Hemolytic-Uremic Syndromes - p. 59 16. Shiga Toxin Associated Hemolytic Uremic Syndrome - p. 67 17. Thrombotic Microangiopathy - p. 74 18. Current and Future Pharmacologic Complement Inhibitors - p. 85 19. Index - p. 97
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