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This issue of Endocrinology and Metabolism Clinics, edited by Adriana G. Ioachimescu, will focus on Cushing’s Syndrome. Topics include--but are not limited to--1. Diagnosis of Cushing’s syndrome in the modern era, Gene mutations in patients with Cushing’s syndrome, Morbidity in Cushing’s syndrome and impact of treatment, Localization of ACTH-dependent Cushing’s syndrome, Prognostic factors of long-term remission after surgical treatment of Cushing’s disease, Outcomes of pituitary radiation for Cushing’s disease, New molecular targets in Cushing’s disease, Recent advances in subclinical Cushing’s syndrome, Adrenal surgery for Cushing’s syndrome, Adrenocortical carcinoma with hypercortisolism, Ectopic Cushing’s syndrome, Medical therapy for Cushing’s syndrome in the 21st century, Pregnancy in patients with Cushing’s syndrome, Mortality in patients with Cushing’s syndrome, and Cushing’s syndrome in children and adolescents.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xii 7. Preface - p. xiii 8. Diagnosis of Cushing’s Syndrome in the Modern Era - p. 259 9. Genetics of Cushing’s Syndrome - p. 275 10. Morbidity of Cushing’s Syndrome and Impact of Treatment - p. 299 11. Mortality in Patients with Endogenous Cushing’s Syndrome - p. 313 12. Prognostic Factors of Long-Term Remission After Surgical Treatment of Cushing’s Disease - p. 335 13. Outcomes of Pituitary Radiation for Cushing’s Disease - p. 349 14. New Molecular Targets for Treatment of Cushing’s Disease - p. 367 15. Recent Advances on Subclinical Hypercortisolism - p. 375 16. Adrenal Surgery for Cushing’s Syndrome: An Update - p. 385 17. Adrenocortical Carcinoma with Hypercortisolism - p. 395 18. The Ectopic Adrenocorticotropic Hormone Syndrome: Rarely Easy, Always Challenging - p. 409 19. Medical Therapy for Cushing’s Syndrome in the Twenty-first Century - p. 427 20. Pregnancy in Patients with Cushing’s Syndrome - p. 441 21. Cushing’s Syndrome in Pediatrics: An Update - p. 451

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This issue of Endocrinology and Metabolism Clinics, edited by Adriana G. Ioachimescu, will focus on Cushing’s Syndrome. Topics include--but are not limited to--1. Diagnosis of Cushing’s syndrome in the modern era, Gene mutations in patients with Cushing’s syndrome, Morbidity in Cushing’s syndrome and impact of treatment, Localization of ACTH-dependent Cushing’s syndrome, Prognostic factors of long-term remission after surgical treatment of Cushing’s disease, Outcomes of pituitary radiation for Cushing’s disease, New molecular targets in Cushing’s disease, Recent advances in subclinical Cushing’s syndrome, Adrenal surgery for Cushing’s syndrome, Adrenocortical carcinoma with hypercortisolism, Ectopic Cushing’s syndrome, Medical therapy for Cushing’s syndrome in the 21st century, Pregnancy in patients with Cushing’s syndrome, Mortality in patients with Cushing’s syndrome, and Cushing’s syndrome in children and adolescents.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xii 7. Preface - p. xiii 8. Diagnosis of Cushing’s Syndrome in the Modern Era - p. 259 9. Genetics of Cushing’s Syndrome - p. 275 10. Morbidity of Cushing’s Syndrome and Impact of Treatment - p. 299 11. Mortality in Patients with Endogenous Cushing’s Syndrome - p. 313 12. Prognostic Factors of Long-Term Remission After Surgical Treatment of Cushing’s Disease - p. 335 13. Outcomes of Pituitary Radiation for Cushing’s Disease - p. 349 14. New Molecular Targets for Treatment of Cushing’s Disease - p. 367 15. Recent Advances on Subclinical Hypercortisolism - p. 375 16. Adrenal Surgery for Cushing’s Syndrome: An Update - p. 385 17. Adrenocortical Carcinoma with Hypercortisolism - p. 395 18. The Ectopic Adrenocorticotropic Hormone Syndrome: Rarely Easy, Always Challenging - p. 409 19. Medical Therapy for Cushing’s Syndrome in the Twenty-first Century - p. 427 20. Pregnancy in Patients with Cushing’s Syndrome - p. 441 21. Cushing’s Syndrome in Pediatrics: An Update - p. 451

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