$178.99 USD
Ver más detalles
Descripcion
Indice
Autores
Muestra
Ficha Técnica
Descripción

For more than 50 years, Dubois’ Lupus Erythematosus and Related Syndromes has been recognized internationally as the go-to clinical reference on lupus and other connective tissue diseases. From basic scientific principles to practical points of clinical management, the updated 9th Edition provides extensive, authoritative coverage of systemic lupus erythematosus (SLE) and its related diseases in a logical, clearly written, user-friendly manner. It’s an ideal resource for rheumatologists and internal medicine practitioners who need a comprehensive clinical reference on all aspects of SLE, connective tissue diseases, and the antiphospholipid syndromes.

  • Provides complete clinical coverage of every aspect of cutaneous and systemic lupus erythematosus, including definitions, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education.
  • Contains an up-to-date overview of significant advances in cellular, molecular, and genetic technologies, including genetic advancements in identifying at-risk patients.
  • Offers an increased focus on the clinical management of related disorders such as Sjogren’s syndrome, scleroderma, polymyositis, and antiphospholipid syndrome (APS).
  • Presents the knowledge and expertise of more international contributors to provide new global perspectives on manifestations, diagnosis, and treatment.
  • Features a vibrant, full-color format, with graphs, algorithms, differential diagnosis comparisons, and more schematic diagrams throughout.

1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Preface - p. iii 6. List of Contributors - p. iii 7. Section 1: What Is Lupus? - p. iii 8. List of Tables - p. iii 9. Chapter 1: History of Lupus - p. iii 10. Chapter 2: Definition and Classification of Lupus and Lupus-Related Disorders - p. iii 11. Chapter 3: The Epidemiology of Lupus - p. iii 12. Section 2: Pathogenesis - p. iii 13. Chapter 4: Overview of Lupus Pathogenesis - p. iii 14. Chapter 5: Genetics of Human SLE - p. iii 15. Chapter 6: Epigenetics of Lupus - p. iii 16. Chapter 7: The Environment and the Host - p. iii 17. Chapter 8: The Innate Immune System in SLE - p. iii 18. Chapter 9: B Cells and Generation of Antibodies - p. iii 19. Chapter 10: T Cells - p. iii 20. Chapter 11: Adaptive and Innate Immunoregulatory Cells - p. iii 21. Chapter 12: Cytokines in Lupus - p. iii 22. Chapter 13: Immunometabolism - p. iii 23. Chapter 14: Animal Models in Lupus - p. iii 24. Section 3: Mechanisms of Tissue Injury - p. iii 25. Chapter 15: Abnormalities in Immune Complex Clearance and Apoptotic Cell Clearance - p. iii 26. Chapter 16: The Role of Complement in SLE - p. iii 27. Chapter 17: Apoptosis and Inflammatory Forms of Cell Death - p. iii 28. Chapter 18: Tissue Damage in Lupus: Free Radicals and Fibrosis - p. iii 29. Chapter 19: Pathogenesis of Fibrosis—The Lung as a Model - p. iii 30. Chapter 20: Pathogenesis of Lupus Nephritis - p. iii 31. Chapter 21: Pathogenesis of Accelerated Atherosclerosis and Vascular Injury in Systemic Lupus Erythematosus - p. iii 32. Chapter 22: Pathogenesis of Cutaneous Lupus - p. iii 33. Chapter 23: Pathogenesis of Neuropsychiatric Lupus - p. iii 34. Chapter 24: Pathogenesis of Antiphospholipid Antibody Syndrome - p. iii 35. Chapter 25: Pathogenesis of Sjögren's - p. iii 36. Section 4: Autoantibodies - p. iii 37. Chapter 26: Structure and Derivation of Autoantibodies - p. iii 38. Chapter 27: Antinuclear Antibodies, Antibodies to DNA, Histones, and Nucleosomes - p. iii 39. Chapter 28: Antibodies Against ENA (Sm, RNP, SSA, SSB) - p. iii 40. Chapter 29: Antibodies Against C1q - p. iii 41. Chapter 30: Antilipoprotein and Antiendothelial Cell Antibodies - p. iii 42. Chapter 31: Drug-Induced Lupus Erythematosus - p. iii 43. Section 5: Clinical Aspects of Lupus Erythematosus - p. iii 44. Chapter 32: Overview and Clinical Presentation - p. iii 45. Chapter 33: Skin Disease in Cutaneous Lupus Erythematosus - p. iii 46. Chapter 34: The Musculoskeletal System and Bone Metabolism - p. iii 47. Chapter 35: Lupus and the Cardiopulmonary System - p. iii 48. Chapter 36: Lupus and the Nervous System: Clinical Aspects, Psychopathology, and Imaging - p. iii 49. Chapter 37: Gastrointestinal and Hepatic Systems - p. iii 50. Chapter 38: Hematologic and Lymphoid Abnormalities in SLE - p. iii 51. Chapter 39: Neonatal Lupus: Pathogenesis and Clinical Approaches - p. iii 52. Chapter 40: Pregnancy and Autoimmune Disease, Reproductive and Hormonal Issues - p. iii 53. Chapter 41: Systemic Lupus Erythematosus in Childhood and Adolescence - p. iii 54. Chapter 42: Clinical Aspects of Antiphospholipid Syndrome - p. iii 55. Chapter 43: Lupus and Infections - p. iii 56. Chapter 44: Ocular, Aural, and Oral Manifestations of Lupus - p. iii 57. Chapter 45: Clinical Aspects of Sjögren's - p. iii 58. Section 6: Assessment of Lupus - p. iii 59. Chapter 46: Clinical Application of Serologic Tests, Serum Protein Abnormalities, and Other Clinical Laboratory Tests in Systemic Lupus Erythematosus - p. iii 60. Chapter 47: Differential Diagnosis and Disease Associations - p. iii 61. Chapter 48: Incomplete Lupus, Undifferentiated Connective Tissue Disease, and Mixed Connective Tissue Disease - p. iii 62. Chapter 49: Clinical Markers, Metrics, Indices, and Clinical Trials - p. iii 63. Chapter 50: Lupus Biomarkers - p. iii 64. Section 7: Management of Lupus - p. iii 65. Chapter 51: Principles of Therapy, Local Measures, and NSAIDs - p. iii 66. Chapter 52: Antimalarial Medications - p. iii 67. Chapter 53: Systemic Glucocorticoid Therapy for SLE - p. iii 68. Chapter 54: Immunosuppressive Drug Therapy - p. iii 69. Chapter 55: Complementary and Alternative Medications, Specialized and Niche Therapies - p. iii 70. Chapter 56: Adjunctive Treatments and Preventive Measures - p. iii 71. Chapter 57: Targeted Therapies in SLE - p. iii 72. Chapter 58: Management of Cutaneous Lupus Erythematosus - p. iii 73. Chapter 59: Epidemiology and Management of Lupus Nephritis - p. iii 74. Chapter 60: Management of Sjögren's - p. iii 75. Section 8: Outcomes - p. iii 76. Chapter 61: Socioeconomic and Disability Aspects - p. iii 77. Chapter 62: Prognosis and Mortality of SLE - p. iii 78. Index - p. iii

No hay muestra disponible

No hay ficha técnica disponible

Descripcion
Descripción

For more than 50 years, Dubois’ Lupus Erythematosus and Related Syndromes has been recognized internationally as the go-to clinical reference on lupus and other connective tissue diseases. From basic scientific principles to practical points of clinical management, the updated 9th Edition provides extensive, authoritative coverage of systemic lupus erythematosus (SLE) and its related diseases in a logical, clearly written, user-friendly manner. It’s an ideal resource for rheumatologists and internal medicine practitioners who need a comprehensive clinical reference on all aspects of SLE, connective tissue diseases, and the antiphospholipid syndromes.

  • Provides complete clinical coverage of every aspect of cutaneous and systemic lupus erythematosus, including definitions, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education.
  • Contains an up-to-date overview of significant advances in cellular, molecular, and genetic technologies, including genetic advancements in identifying at-risk patients.
  • Offers an increased focus on the clinical management of related disorders such as Sjogren’s syndrome, scleroderma, polymyositis, and antiphospholipid syndrome (APS).
  • Presents the knowledge and expertise of more international contributors to provide new global perspectives on manifestations, diagnosis, and treatment.
  • Features a vibrant, full-color format, with graphs, algorithms, differential diagnosis comparisons, and more schematic diagrams throughout.

1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Preface - p. iii 6. List of Contributors - p. iii 7. Section 1: What Is Lupus? - p. iii 8. List of Tables - p. iii 9. Chapter 1: History of Lupus - p. iii 10. Chapter 2: Definition and Classification of Lupus and Lupus-Related Disorders - p. iii 11. Chapter 3: The Epidemiology of Lupus - p. iii 12. Section 2: Pathogenesis - p. iii 13. Chapter 4: Overview of Lupus Pathogenesis - p. iii 14. Chapter 5: Genetics of Human SLE - p. iii 15. Chapter 6: Epigenetics of Lupus - p. iii 16. Chapter 7: The Environment and the Host - p. iii 17. Chapter 8: The Innate Immune System in SLE - p. iii 18. Chapter 9: B Cells and Generation of Antibodies - p. iii 19. Chapter 10: T Cells - p. iii 20. Chapter 11: Adaptive and Innate Immunoregulatory Cells - p. iii 21. Chapter 12: Cytokines in Lupus - p. iii 22. Chapter 13: Immunometabolism - p. iii 23. Chapter 14: Animal Models in Lupus - p. iii 24. Section 3: Mechanisms of Tissue Injury - p. iii 25. Chapter 15: Abnormalities in Immune Complex Clearance and Apoptotic Cell Clearance - p. iii 26. Chapter 16: The Role of Complement in SLE - p. iii 27. Chapter 17: Apoptosis and Inflammatory Forms of Cell Death - p. iii 28. Chapter 18: Tissue Damage in Lupus: Free Radicals and Fibrosis - p. iii 29. Chapter 19: Pathogenesis of Fibrosis—The Lung as a Model - p. iii 30. Chapter 20: Pathogenesis of Lupus Nephritis - p. iii 31. Chapter 21: Pathogenesis of Accelerated Atherosclerosis and Vascular Injury in Systemic Lupus Erythematosus - p. iii 32. Chapter 22: Pathogenesis of Cutaneous Lupus - p. iii 33. Chapter 23: Pathogenesis of Neuropsychiatric Lupus - p. iii 34. Chapter 24: Pathogenesis of Antiphospholipid Antibody Syndrome - p. iii 35. Chapter 25: Pathogenesis of Sjögren's - p. iii 36. Section 4: Autoantibodies - p. iii 37. Chapter 26: Structure and Derivation of Autoantibodies - p. iii 38. Chapter 27: Antinuclear Antibodies, Antibodies to DNA, Histones, and Nucleosomes - p. iii 39. Chapter 28: Antibodies Against ENA (Sm, RNP, SSA, SSB) - p. iii 40. Chapter 29: Antibodies Against C1q - p. iii 41. Chapter 30: Antilipoprotein and Antiendothelial Cell Antibodies - p. iii 42. Chapter 31: Drug-Induced Lupus Erythematosus - p. iii 43. Section 5: Clinical Aspects of Lupus Erythematosus - p. iii 44. Chapter 32: Overview and Clinical Presentation - p. iii 45. Chapter 33: Skin Disease in Cutaneous Lupus Erythematosus - p. iii 46. Chapter 34: The Musculoskeletal System and Bone Metabolism - p. iii 47. Chapter 35: Lupus and the Cardiopulmonary System - p. iii 48. Chapter 36: Lupus and the Nervous System: Clinical Aspects, Psychopathology, and Imaging - p. iii 49. Chapter 37: Gastrointestinal and Hepatic Systems - p. iii 50. Chapter 38: Hematologic and Lymphoid Abnormalities in SLE - p. iii 51. Chapter 39: Neonatal Lupus: Pathogenesis and Clinical Approaches - p. iii 52. Chapter 40: Pregnancy and Autoimmune Disease, Reproductive and Hormonal Issues - p. iii 53. Chapter 41: Systemic Lupus Erythematosus in Childhood and Adolescence - p. iii 54. Chapter 42: Clinical Aspects of Antiphospholipid Syndrome - p. iii 55. Chapter 43: Lupus and Infections - p. iii 56. Chapter 44: Ocular, Aural, and Oral Manifestations of Lupus - p. iii 57. Chapter 45: Clinical Aspects of Sjögren's - p. iii 58. Section 6: Assessment of Lupus - p. iii 59. Chapter 46: Clinical Application of Serologic Tests, Serum Protein Abnormalities, and Other Clinical Laboratory Tests in Systemic Lupus Erythematosus - p. iii 60. Chapter 47: Differential Diagnosis and Disease Associations - p. iii 61. Chapter 48: Incomplete Lupus, Undifferentiated Connective Tissue Disease, and Mixed Connective Tissue Disease - p. iii 62. Chapter 49: Clinical Markers, Metrics, Indices, and Clinical Trials - p. iii 63. Chapter 50: Lupus Biomarkers - p. iii 64. Section 7: Management of Lupus - p. iii 65. Chapter 51: Principles of Therapy, Local Measures, and NSAIDs - p. iii 66. Chapter 52: Antimalarial Medications - p. iii 67. Chapter 53: Systemic Glucocorticoid Therapy for SLE - p. iii 68. Chapter 54: Immunosuppressive Drug Therapy - p. iii 69. Chapter 55: Complementary and Alternative Medications, Specialized and Niche Therapies - p. iii 70. Chapter 56: Adjunctive Treatments and Preventive Measures - p. iii 71. Chapter 57: Targeted Therapies in SLE - p. iii 72. Chapter 58: Management of Cutaneous Lupus Erythematosus - p. iii 73. Chapter 59: Epidemiology and Management of Lupus Nephritis - p. iii 74. Chapter 60: Management of Sjögren's - p. iii 75. Section 8: Outcomes - p. iii 76. Chapter 61: Socioeconomic and Disability Aspects - p. iii 77. Chapter 62: Prognosis and Mortality of SLE - p. iii 78. Index - p. iii

Indice
Autores
Muestra

No hay muestra disponible

Ficha Técnica

No hay ficha técnica disponible