Designed for quick, everyday reference, Handbook of Targeted Cancer Therapy and Immunotherapy: Breast Cancer provides a practical overview of this rapidly advancing field. Comprehensive yet concise, this easy-access resource by Drs. Senthil Damodaran and Debu Tripathy of MD Anderson Cancer Center helps you filter and apply the most recent discoveries as they pertain to specific tumor types, actionable molecular targets, and clinical performance of approved or investigational targeted agents and combinations of agents.
1. Cover - p. i 2. Title Page - p. iii 3. Copyright Page - p. iv 4. Contributors - p. v 5. Preface - p. vii 6. Acknowledgments - p. ix 7. Contents - p. x 8. SECTION 1: Targets of Interest in Breast Cancer - p. 1 9. CHAPTER 1: Androgen Receptor - p. 5 10. CHAPTER 2: BRCA1/2 - p. 9 11. CHAPTER 3: ESR1 - p. 15 12. CHAPTER 4: PIK3CA - p. 19 13. CHAPTER 5: HER2 (ERBB2) Mutations - p. 27 14. CHAPTER 6: Akt1 and PTEN - p. 31 15. CHAPTER 7: FGFR - p. 40 16. CHAPTER 8: NTRK - p. 44 17. CHAPTER 9: HER2 Amplifications - p. 47 18. CHAPTER 10: PD-1/PD-L1/MSI/TMB - p. 54 19. CHAPTER 11: TROP-2 - p. 61 20. SECTION 2: Molecular Diagnostics and Testing - p. 65 21. SECTION 3: Molecular Targets and Pathways - p. 105 22. SECTION 4: Targeted and Immunotherapy Agents - p. 212 23. Index - p. 288
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Designed for quick, everyday reference, Handbook of Targeted Cancer Therapy and Immunotherapy: Breast Cancer provides a practical overview of this rapidly advancing field. Comprehensive yet concise, this easy-access resource by Drs. Senthil Damodaran and Debu Tripathy of MD Anderson Cancer Center helps you filter and apply the most recent discoveries as they pertain to specific tumor types, actionable molecular targets, and clinical performance of approved or investigational targeted agents and combinations of agents.
1. Cover - p. i 2. Title Page - p. iii 3. Copyright Page - p. iv 4. Contributors - p. v 5. Preface - p. vii 6. Acknowledgments - p. ix 7. Contents - p. x 8. SECTION 1: Targets of Interest in Breast Cancer - p. 1 9. CHAPTER 1: Androgen Receptor - p. 5 10. CHAPTER 2: BRCA1/2 - p. 9 11. CHAPTER 3: ESR1 - p. 15 12. CHAPTER 4: PIK3CA - p. 19 13. CHAPTER 5: HER2 (ERBB2) Mutations - p. 27 14. CHAPTER 6: Akt1 and PTEN - p. 31 15. CHAPTER 7: FGFR - p. 40 16. CHAPTER 8: NTRK - p. 44 17. CHAPTER 9: HER2 Amplifications - p. 47 18. CHAPTER 10: PD-1/PD-L1/MSI/TMB - p. 54 19. CHAPTER 11: TROP-2 - p. 61 20. SECTION 2: Molecular Diagnostics and Testing - p. 65 21. SECTION 3: Molecular Targets and Pathways - p. 105 22. SECTION 4: Targeted and Immunotherapy Agents - p. 212 23. Index - p. 288
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