IASLC Thoracic Oncology

1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Preface - p. iii 7. List of Illustrations - p. iii 8. List of Tables - p. iii 9. Section I: Lung Cancer Control and Epidemiology - p. iii 10. Chapter 1: Classic Epidemiology of Lung Cancer - p. iii 11. Chapter 2: Tobacco Control and Primary Prevention - p. g7 12. Chapter 3: Assessing and Treating Tobacco Use in Lung Cancer Care - p. g17 13. Chapter 4: Lung Cancer in Never-Smokers: A Different Disease - p. g22 14. Chapter 5: Gender-Related Differences in Lung Cancer - p. g28 15. Chapter 6: Genetic Susceptibility to Lung Cancer - p. g45 16. Chapter 7: Screening for Lung Cancer - p. g51 17. Chapter 8: Preclinical Biomarkers for the Early Detection of Lung Cancer - p. g58 18. Chapter 9: Chemoprevention of Lung Cancer and Management of Early Lung Cancer - p. g68 19. Section II: Lung Cancer Molecular Carcinogenesis - p. g80 20. Chapter 10: Copy Number Abnormalities and Gene Fusions in Lung Cancer: Present and Developing Technologies - p. g80 21. Chapter 11: Mutational Events in Lung Cancer: Present and Developing Technologies - p. g93 22. Chapter 12: Epigenetic Events in Lung Cancer: Chromatin Remodeling and DNA Methylation - p. g103 23. Chapter 13: Stem Cells and Lung Cancer: In Vitro and In Vivo Studies - p. g116 24. Chapter 14: Microenvironment and Lung Cancer - p. g120 25. Chapter 15: MicroRNAs as Biomarkers for Lung Cancer - p. g127 26. Section III: Immunology - p. g136 27. Chapter 16: Humoral and Cellular Immune Dysregulation and Lung Cancer - p. g136 28. Section IV: Pathology - p. g142 29. Chapter 17: Classic Anatomic Pathology and Lung Cancer - p. g142 30. Chapter 18: Molecular Testing in Lung Cancer - p. g162 31. Chapter 19: Management of Small Histologic and Cytologic Specimens in the Molecular Era - p. g176 32. Section V: Clinical and Radiologic Presentation of Lung Cancer - p. g185 33. Chapter 20: Clinical Presentation and Prognostic Factors in Lung Cancer - p. g185 34. Chapter 21: Conventional Imaging of Lung Cancer - p. g197 35. Chapter 22: Positron Emission Tomography Imaging of Lung Cancer - p. g218 36. Section VI: Diagnosis and Staging of Lung Cancer - p. g232 37. Chapter 23: Diagnostic Workup for Suspected Lung Cancer Confined to the Chest - p. g232 38. Chapter 24: Preoperative and Intraoperative Invasive Staging of the Mediastinum - p. g239 39. Chapter 25: The Eighth Edition of the Tumor, Node, and Metastasis Classification of Lung Cancer - p. g252 40. Section VII: Surgical Management of Lung Cancer - p. g264 41. Chapter 26: Preoperative Functional Evaluation of the Surgical Candidate - p. g264 42. Chapter 27: Results of Video-Assisted Techniques for Resection of Lung Cancer - p. g272 43. Chapter 28: Robotic Surgery: Techniques and Results for Resection of Lung Cancer - p. g281 44. Chapter 29: Extent of Surgical Resection for Stage I and II Lung Cancer - p. g287 45. Chapter 30: Extended Resections for Lung Cancer: Chest Wall and Pancoast Tumors - p. g294 46. Chapter 31: Extended Resections for Lung Cancer: Bronchovascular Sleeve Resections - p. g303 47. Chapter 32: Multiple Nodules: Management of Synchronous and Metachronous Lung Cancers - p. g307 48. Chapter 33: Surgical Management of Patients Considered Marginally Resectable - p. g313 49. Section VIII: Radiotherapeutic Management of Lung Cancer - p. g317 50. Chapter 34: Technical Requirements for Lung Cancer Radiotherapy - p. g317 51. Chapter 35: Radiobiology of Lung Cancer - p. g328 52. Chapter 36: Patient Selection for Radiotherapy - p. g336 53. Chapter 37: Stage I Nonsmall Cell Lung Cancer and Oligometastatic Disease - p. g341 54. Chapter 38: Ablation Options for Localized Nonsmall Cell Lung Cancer - p. g353 55. Chapter 39: Radiotherapy for Locally Advanced Nonsmall Cell Lung Cancer Including Combined Modality - p. g362 56. Chapter 40: Radiotherapy in the Management of Small Cell Lung Cancer: Thoracic Radiotherapy, Prophylactic Cranial Irradiation - p. g373 57. Chapter 41: Palliative Radiotherapy for Lung Cancer - p. g381 58. Chapter 42: Acute and Late Toxicities of Thoracic Radiotherapy: Pulmonary, Esophagus, and Heart - p. g392 59. Chapter 43: Neurotoxicity Related to Radiotherapy and Chemotherapy for Nonsmall Cell and Small Cell Lung Cancer - p. g408 60. Section IX: Chemotherapy and Targeted Agents for Lung Cancer - p. g417 61. Chapter 44: Frontline Systemic Therapy Options in Nonsmall Cell Lung Cancer - p. g417 62. Chapter 45: Systemic Options for Second-Line Therapy and Beyond - p. g432 63. Chapter 46: Maintenance Chemotherapy for Nonsmall Cell Lung Cancer - p. g446 64. Chapter 47: Pharmacogenomics in Lung Cancer: Predictive Biomarkers for Chemotherapy - p. g465 65. Chapter 48: New Targets for Therapy in Lung Cancer - p. g478 66. Chapter 49: Management of Toxicities of Targeted Therapies - p. g489 67. Chapter 50: Immunotherapy and Lung Cancer - p. g500 68. Chapter 51: Adjuvant and Neoadjuvant Chemotherapy for Early-Stage Nonsmall Cell Lung Cancer - p. g510 69. Chapter 52: Treatment of Extensive-Stage Small Cell Lung Cancer - p. g524 70. Section X: Other Thoracic Malignancies - p. g535 71. Chapter 53: Malignant Mesothelioma - p. g535 72. Chapter 54: Mediastinal Tumors - p. g549 73. Chapter 55: Neuroendocrine Tumors of the Lung Other Than Small Cell Lung Cancer - p. g554 74. Chapter 56: Thymic Tumors - p. g568 75. Section XI: Symptom Management and Complications - p. g589 76. Chapter 57: Lung Cancer Emergencies - p. g589 77. Chapter 58: The Role of Palliative Care in Lung Cancer - p. g607 78. Section XII: Clinical Trials - p. g619 79. Chapter 59: Clinical Trial Methodology in Lung Cancer: Study Design and End-Point Considerations - p. g619 80. Chapter 60: How to Promote and Organize Clinical Research in Lung Cancer - p. g627 81. Section XIII: Thoracic Oncology Advocacy - p. g634 82. Chapter 61: The Role of Advocacy Groups in Lung Cancer - p. g634 83. Chapter 62: The Role of Health Services Research in Improving the Outcomes for Patients With Lung Cancer - p. g638 84. Appendix - p. g649 85. Diagnostic Algorithms - p. g649 86. Index - p. g657