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For over 60 years, residents and practicing pathologists have turned to Rosai and Ackerman's Surgical Pathology for definitive guidance on every aspect of the field, delivered in a readable, easy-to-digest, and engaging manner. In the 11th Edition, a dynamic new author team ensures that this classic text retains its signature anecdotal style, while revising the content to bring you fully up to date. Widely used for board exam preparation, as well as for everyday reference in practice, this leading resource equips you to effectively and efficiently diagnose the complete range of neoplastic and non-neoplastic entities.

  • Provides comprehensive coverage of the clinical presentation, gross and microscopic features, ultrastructural and immunohistochemical findings, prognosis, and therapy for virtually every pathologic lesion.
  • Presents content now grouped in sections corresponding to organs and systems, making disease entities easier to locate.
  • Includes state-of-the-art coverage of the latest disease classifications, molecular biology and pathology, immunohistochemistry, genetics, prognostic/predictive markers, and more – all highlighted by more than 3,000 full-color illustrations of commonly seen pathologies.
  • Showcases the knowledge and expertise of an innovative new author team: prolific author John R. Goldblum, MD (GI pathology, soft tissue tumors); Laura Lamps, MD (hepatobiliary, endocrine tumors, infectious disease); Jesse McKenney, MD (GU/GYN, soft tissue tumors); and Jeff Myers, MD (pulmonary, pleural, mediastinum); accompanied by a select list of subspecialty contributors.
  • Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.

1. 1 Introduction - p. 1 2. Section 1 Dermatopathology - p. 3 3. 2 Dermatoses - p. 6 4. Abstract - p. 6 5. Introduction to Dermatopathology - p. 7 6. Normal Anatomy - p. 6.e1 7. Inflammatory Dermatoses - p. 8 8. Inflammatory Dermatoses With Epidermal Change - p. 8 9. Inflammatory Dermatoses With Dermal but Not Epidermal Change - p. 15 10. Sclerosing Disorders - p. 22 11. Panniculitis - p. 23 12. Vesiculobullous Diseases - p. 25 13. Infections - p. 29 14. Miscellaneous Disorders - p. 35 15. References - p. 37 16. 3 Tumors and Tumorlike Conditions of the Skin - p. 45 17. Abstract - p. 45 18. Epidermis - p. 45.e1 19. Squamous Cell Carcinoma - p. 48 20. Pseudoepitheliomatous Hyperplasia - p. 50 21. Basal Cell Carcinoma - p. 50 22. Skin Adnexa - p. 54 23. Melanocytes - p. 67 24. Neuroendocrine Cells - p. 87 25. Dermis - p. 90 26. Vascular Tumors and Tumorlike Conditions - p. 98 27. Lymphoid Tumors and Tumorlike Conditions - p. 105 28. Other Primary Tumors and Tumorlike Conditions - p. 111 29. Metastatic Tumors - p. 111 30. References - p. 113 31. Section 2 Head and Neck Pathology - p. 143 32. 4 Upper Aerodigestive Tract - p. 146 33. Abstract - p. 146 34. Oral Cavity and Oropharynx - p. 147 35. Respiratory Tract - p. 164 36. Larynx - p. 183 37. Trachea - p. 196 38. References - p. 197 39. 5 Mandible and Maxilla - p. 212 40. 6 Major and Minor Salivary Glands - p. 235 41. Abstract - p. 235 42. Normal Anatomy - p. 236 43. Heterotopia - p. 235.e1 44. Sialolithiasis - p. 235.e1 45. Sialadenitis - p. 235.e1 46. Benign Lymphoepithelial Cysts and HIV-Related Lesions - p. 237 47. Lymphoepithelial Sialadenitis (Mikulicz Disease) and Sjögren Syndrome - p. 238 48. Irradiation Effect - p. 239 49. Other Non-Neoplastic Lesions - p. 239 50. Epithelial Tumors - p. 240 51. Malignant Lymphoma - p. 256 52. Other Primary Tumors - p. 256 53. Metastatic Tumors - p. 257 54. General Features of Salivary Gland Tumors - p. 257 55. References - p. 259 56. 7 Ear - p. 269 57. 8 Thyroid Gland - p. 278 58. Abstract - p. 278 59. Normal Anatomy and Thyroid Gland Development - p. 279 60. Congenital Abnormalities - p. 280 61. Thyroiditis - p. 282 62. Hyperplasia - p. 287 63. Tumors - p. 293 64. References - p. 335 65. 9 Parathyroid Glands - p. 355 66. Section 3 Thoracic Pathology - p. 369 67. 10 Lung - p. 372 68. Abstract - p. 372 69. Normal Anatomy - p. 373 70. Non-Neoplastic Lesions - p. 372.e1 71. Carcinoma - p. 399 72. Other Primary Tumors - p. 418 73. Metastatic Tumors - p. 429 74. References - p. 431 75. 11 Pleura - p. 444 76. 12 Mediastinum - p. 457 77. Abstract - p. 457 78. Generalities - p. 458 79. Inflammatory Diseases - p. 458 80. Cysts (Other Than Thymic) - p. 459 81. Thymus - p. 460 82. Malignant Lymphoma - p. 484 83. Neurogenic Tumors - p. 489 84. Tumors of Paraganglia - p. 490 85. Mesenchymal Tumors - p. 491 86. Metastatic Tumors - p. 492 87. References - p. 492 88. Section 4 Gastrointestinal and Hepatobiliary Tract - p. 500 89. 13 Esophagus - p. 502 90. 14 Stomach - p. 528 91. Abstract - p. 528 92. Normal Anatomy - p. 529 93. Heterotopic Tissues - p. 528.e1 94. Hypertrophic Pyloric Stenosis - p. 530 95. Chronic Gastritis - p. 530 96. Other Types of Gastritis - p. 532 97. Peptic and Other Benign Ulcers - p. 533 98. Other Non-Neoplastic Lesions - p. 535 99. Polyps - p. 536 100. Ménétrier Disease and Zollinger–Ellison Syndrome - p. 539 101. Regenerative Changes and Dysplasia - p. 539 102. Carcinoma - p. 541 103. Well-Differentiated Neuroendocrine Tumors (“Carcinoid Tumors”) - p. 548 104. Stromal Tumors (Gastrointestinal Stromal Tumors and Related Lesions) - p. 550 105. Lymphoid Tumors and Tumorlike Conditions - p. 553 106. Other Tumors - p. 557 107. References - p. 559 108. 15 Small Bowel - p. 568 109. Abstract - p. 568 110. Normal Anatomy - p. 569 111. Congenital Defects - p. 570 112. Inflammatory Disorders - p. 572 113. Polyps and Tumors - p. 590 114. References - p. 605 115. 16 Appendix - p. 617 116. 17 Large Bowel - p. 648 117. Abstract - p. 648 118. Normal Anatomy of the Large Bowel - p. 649 119. Hirschsprung Disease and Related Disorders - p. 648.e1 120. Diverticulosis - p. 651 121. Colitis - p. 652 122. Other Non-Neoplastic Lesions - p. 663 123. Tumors - p. 668 124. References - p. 689 125. 18 Anus - p. 703 126. 19 Liver - p. 726 127. Abstract - p. 726 128. Normal Anatomy - p. 727 129. Biopsy - p. 726.e1 130. Viral Hepatitis - p. 728 131. Drug-Induced and Toxic Liver Injury - p. 739 132. Steatosis and Steatohepatitis - p. 744 133. Cholestasis, Biliary Diseases, and Autoimmune Hepatitis - p. 750 134. Cirrhosis - p. 761 135. Childhood Disorders and Disorders of Metabolism - p. 762 136. Disorders of Copper and Iron Metabolism - p. 769 137. Fibropolycystic Diseases (Ductal Plate Malformation) - p. 772 138. Vascular Disorders - p. 775 139. Liver Disease in Pregnancy - p. 777 140. Liver Involvement in Systemic Diseases - p. 777 141. Liver Pathology in Organ Transplantation - p. 781 142. References - p. 785 143. 20 Liver - p. 803 144. Abstract - p. 803 145. Hepatic Tumors and Tumorlike Conditions - p. 804 146. Bile Duct Tumors and Tumorlike Conditions - p. 819 147. Mesenchymal Tumors and Tumorlike Conditions - p. 824 148. Malignant Lymphoma and Related Lesions - p. 829 149. Other Primary Tumors and Tumorlike Conditions - p. 831 150. Metastatic Tumors - p. 831 151. References - p. 833 152. 21 Gallbladder and Extrahepatic Bile Ducts - p. 844 153. 22 Pancreas and Ampullary Region - p. 886 154. Abstract - p. 886 155. Pancreas - p. 887 156. Ampullary Region - p. 921 157. References - p. 923 158. Volume 2 - p. 933 159. Section 5 Genitourinary Pathology - p. 933 160. 23 Kidney - p. 936 161. Abstract - p. 936 162. Renal Biopsy - p. 936.e1 163. Normal Structure of the Glomerulus - p. 938 164. Classification of Glomerular Disease - p. 940 165. Glomerular Lesions Associated With the Nephrotic Syndrome - p. 940 166. Glomerular Lesions Associated With the Syndrome of Acute Nephritis - p. 958 167. Glomerular Lesions Associated With Vascular Diseases - p. 973 168. Renal Diseases of Pregnancy - p. 979 169. Hereditary Glomerular Diseases - p. 980 170. Renal Transplant Pathology - p. 984 171. Tubulointerstitial Diseases - p. 989 172. Renal Vascular Disease - p. 995 173. Radiation Nephropathy - p. 998 174. Cystic Diseases of the Kidney - p. 998 175. References - p. 1002 176. 24 Kidney - p. 1014 177. Abstract - p. 1014 178. Pediatric Tumors and Tumorlike Conditions - p. 1015 179. Adult Tumors and Tumorlike Conditions - p. 1025 180. References - p. 1049 181. 25 Bladder - p. 1066 182. 26 Prostate and Seminal Vesicles - p. 1097 183. Abstract - p. 1097 184. Prostate - p. 1098 185. Prostatic Urethra - p. 1121 186. Seminal Vesicles and Cowper's Glands - p. 1121 187. References - p. 1122 188. 27 Testis and Testicular Adnexa - p. 1135 189. Abstract - p. 1135 190. Testis - p. 1136 191. Testicular Adnexa - p. 1157 192. References - p. 1164 193. 28 Penis and Scrotum - p. 1175 194. 29 Adrenal Gland and Other Paraganglia - p. 1190 195. Section 6 Female Reproductive System - p. 1221 196. 30 Vulva - p. 1224 197. 31 Vagina - p. 1248 198. 32 Uterus - p. 1260 199. Abstract - p. 1260 200. Normal Anatomy - p. 1261 201. Remnants and Ectopias - p. 1261 202. Squamous and Other Metaplasias - p. 1260.e1 203. Inflammatory Lesions - p. 1263 204. Non-Neoplastic Glandular Lesions - p. 1263 205. Non-Neoplastic Stromal Lesions (Including Endometriosis and Related Processes) - p. 1265 206. Human Papilloma Virus and the Lower Female Genital Tract - p. 1266 207. Tumors - p. 1267 208. References - p. 1284 209. 33 Uterus - p. 1294 210. Abstract - p. 1294 211. Normal Anatomy - p. 1295 212. Effects of Hormone Administration - p. 1296 213. Endometritis - p. 1297 214. Metaplasia - p. 1298 215. Adenomyosis and Endometriosis - p. 1300 216. Dysfunctional Uterine Bleeding - p. 1302 217. Endometrial Hyperplasia Without Atypia, Atypical Hyperplasia, and Variants - p. 1303 218. Curettage and Biopsy - p. 1305 219. Tumors - p. 1306 220. References - p. 1340 221. 34 Fallopian Tube - p. 1356 222. 35 Ovary - p. 1367 223. Abstract - p. 1367 224. Normal Anatomy - p. 1368 225. Gonadal Dysgenesis - p. 1367.e1 226. Cysts, Stromal Hyperplasia, and Other Non-Neoplastic Lesions - p. 1369 227. Inflammation - p. 1373 228. Endometriosis - p. 1374 229. Tumors - p. 1374 230. References - p. 1417 231. Section 7 Breast - p. 1431 232. 36 Breast - p. 1434 233. Abstract - p. 1434 234. Normal Anatomy - p. 1435 235. Ectopia - p. 1436 236. Inflammatory and Related Lesions - p. 1437 237. Benign Breast Disease - p. 1440 238. Intraductal Proliferative Lesions and Nonproliferative Changes - p. 1440 239. Fibroepithelial Lesions - p. 1447 240. Adenosis and Sclerosing Lesions - p. 1451 241. Papillary Lesions - p. 1456 242. Nipple Lesions - p. 1462 243. Carcinoma - p. 1464 244. Salivary Gland and Skin Adnexal-Type Tumors (Including Myoepithelial Tumors) - p. 1503 245. Stromal and Vascular Tumors and Tumorlike Conditions - p. 1504 246. Lymphoid Tumors and Tumorlike Conditions - p. 1506 247. Other Primary Tumors and Tumorlike Conditions - p. 1507 248. Metastatic Tumors - p. 1509 249. Breast Diseases in Children and Adolescents - p. 1510 250. Breast Diseases in Males - p. 1511 251. References - p. 1512 252. Section 8 Hematopathology - p. 1527 253. 37 Lymph Nodes - p. 1530 254. Abstract - p. 1530 255. Normal Anatomy - p. 1531 256. Lymph Node Evaluation - p. 1530.e1 257. Primary Immunodeficiencies - p. 1538 258. Patterns of Hyperplasia - p. 1539 259. Inflammatory/Hyperplastic Diseases - p. 1543 260. Malignant Lymphoma - p. 1561 261. Tumors of the Accessory Immune System - p. 1594 262. Vascular Tumors and Tumorlike Conditions - p. 1597 263. Other Primary Tumors and Tumorlike Conditions - p. 1598 264. Lymph Node Inclusions - p. 1601 265. Other Non-Neoplastic Lesions - p. 1604 266. Metastatic Tumors - p. 1605 267. References - p. 1610 268. 38 Spleen - p. 1632 269. 39 Bone Marrow - p. 1658 270. Abstract - p. 1658 271. Biopsy Procedure and Processing of Specimen - p. 1659 272. Immunohistochemistry - p. 1660 273. Normocellular Bone Marrow - p. 1662 274. Alterations in Cellularity - p. 1663 275. Osteopetrosis - p. 1665 276. Bone Marrow Necrosis - p. 1665 277. Inflammatory Disorders - p. 1666 278. Human Immunodeficiency Virus Syndrome (HIV, AIDS) - p. 1669 279. Leukemias and Related Disorders - p. 1670 280. Systemic Mastocytosis - p. 1684 281. Mature B-Cell Neoplasms - p. 1687 282. Non-Hodgkin Lymphoma - p. 1693 283. Benign Lymphocytic Aggregates - p. 1703 284. Hodgkin Lymphoma - p. 1704 285. Histiocytic Disorders - p. 1706 286. Plasma Cell Dyscrasias - p. 1709 287. Systemic Polyclonal B-Immunoblastic Proliferation - p. 1716 288. Metastatic Tumors - p. 1717 289. Lipid Storage Diseases - p. 1719 290. Hematopoietic Cell Transplantation - p. 1721 291. Acknowledgment - p. 1724 292. References - p. 1724 293. Section 9 Bone and Soft Tissue Pathology - p. 1737 294. 40 Bone and Joints - p. 1740 295. Abstract - p. 1740 296. Bone - p. 1741 297. Joints and Related Structures - p. 1789 298. References - p. 1797 299. 41 Soft Tissues - p. 1810 300. Abstract - p. 1810 301. Normal Anatomy - p. 1811 302. Infections and Hematomas - p. 1810.e1 303. Tumors - p. 1810.e1 304. References - p. 1892 305. Section 10 Cardiovascular Pathology - p. 1914 306. 42 Cardiovascular System - p. 1916 307. Section 11 Central Nervous System - p. 1945 308. 43 Central Nervous System - p. 1948 309. Abstract - p. 1948 310. Normal Anatomy - p. 1949 311. Developmental Abnormalities - p. 1948.e1 312. Cerebrovascular Disorders - p. 1955 313. Inflammatory Diseases - p. 1962 314. Infectious Diseases - p. 1967 315. Primary Tumors - p. 1977 316. Secondary/Metastatic Tumors - p. 2059 317. Acknowledgments - p. 2061 318. References - p. 2061 319. 44 Pituitary Gland - p. 2086 320. 45 Eye and Ocular Adnexa - p. 2112 321. Index - p. I-1

Descripcion
Descripción

For over 60 years, residents and practicing pathologists have turned to Rosai and Ackerman's Surgical Pathology for definitive guidance on every aspect of the field, delivered in a readable, easy-to-digest, and engaging manner. In the 11th Edition, a dynamic new author team ensures that this classic text retains its signature anecdotal style, while revising the content to bring you fully up to date. Widely used for board exam preparation, as well as for everyday reference in practice, this leading resource equips you to effectively and efficiently diagnose the complete range of neoplastic and non-neoplastic entities.

  • Provides comprehensive coverage of the clinical presentation, gross and microscopic features, ultrastructural and immunohistochemical findings, prognosis, and therapy for virtually every pathologic lesion.
  • Presents content now grouped in sections corresponding to organs and systems, making disease entities easier to locate.
  • Includes state-of-the-art coverage of the latest disease classifications, molecular biology and pathology, immunohistochemistry, genetics, prognostic/predictive markers, and more – all highlighted by more than 3,000 full-color illustrations of commonly seen pathologies.
  • Showcases the knowledge and expertise of an innovative new author team: prolific author John R. Goldblum, MD (GI pathology, soft tissue tumors); Laura Lamps, MD (hepatobiliary, endocrine tumors, infectious disease); Jesse McKenney, MD (GU/GYN, soft tissue tumors); and Jeff Myers, MD (pulmonary, pleural, mediastinum); accompanied by a select list of subspecialty contributors.
  • Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.

1. 1 Introduction - p. 1 2. Section 1 Dermatopathology - p. 3 3. 2 Dermatoses - p. 6 4. Abstract - p. 6 5. Introduction to Dermatopathology - p. 7 6. Normal Anatomy - p. 6.e1 7. Inflammatory Dermatoses - p. 8 8. Inflammatory Dermatoses With Epidermal Change - p. 8 9. Inflammatory Dermatoses With Dermal but Not Epidermal Change - p. 15 10. Sclerosing Disorders - p. 22 11. Panniculitis - p. 23 12. Vesiculobullous Diseases - p. 25 13. Infections - p. 29 14. Miscellaneous Disorders - p. 35 15. References - p. 37 16. 3 Tumors and Tumorlike Conditions of the Skin - p. 45 17. Abstract - p. 45 18. Epidermis - p. 45.e1 19. Squamous Cell Carcinoma - p. 48 20. Pseudoepitheliomatous Hyperplasia - p. 50 21. Basal Cell Carcinoma - p. 50 22. Skin Adnexa - p. 54 23. Melanocytes - p. 67 24. Neuroendocrine Cells - p. 87 25. Dermis - p. 90 26. Vascular Tumors and Tumorlike Conditions - p. 98 27. Lymphoid Tumors and Tumorlike Conditions - p. 105 28. Other Primary Tumors and Tumorlike Conditions - p. 111 29. Metastatic Tumors - p. 111 30. References - p. 113 31. Section 2 Head and Neck Pathology - p. 143 32. 4 Upper Aerodigestive Tract - p. 146 33. Abstract - p. 146 34. Oral Cavity and Oropharynx - p. 147 35. Respiratory Tract - p. 164 36. Larynx - p. 183 37. Trachea - p. 196 38. References - p. 197 39. 5 Mandible and Maxilla - p. 212 40. 6 Major and Minor Salivary Glands - p. 235 41. Abstract - p. 235 42. Normal Anatomy - p. 236 43. Heterotopia - p. 235.e1 44. Sialolithiasis - p. 235.e1 45. Sialadenitis - p. 235.e1 46. Benign Lymphoepithelial Cysts and HIV-Related Lesions - p. 237 47. Lymphoepithelial Sialadenitis (Mikulicz Disease) and Sjögren Syndrome - p. 238 48. Irradiation Effect - p. 239 49. Other Non-Neoplastic Lesions - p. 239 50. Epithelial Tumors - p. 240 51. Malignant Lymphoma - p. 256 52. Other Primary Tumors - p. 256 53. Metastatic Tumors - p. 257 54. General Features of Salivary Gland Tumors - p. 257 55. References - p. 259 56. 7 Ear - p. 269 57. 8 Thyroid Gland - p. 278 58. Abstract - p. 278 59. Normal Anatomy and Thyroid Gland Development - p. 279 60. Congenital Abnormalities - p. 280 61. Thyroiditis - p. 282 62. Hyperplasia - p. 287 63. Tumors - p. 293 64. References - p. 335 65. 9 Parathyroid Glands - p. 355 66. Section 3 Thoracic Pathology - p. 369 67. 10 Lung - p. 372 68. Abstract - p. 372 69. Normal Anatomy - p. 373 70. Non-Neoplastic Lesions - p. 372.e1 71. Carcinoma - p. 399 72. Other Primary Tumors - p. 418 73. Metastatic Tumors - p. 429 74. References - p. 431 75. 11 Pleura - p. 444 76. 12 Mediastinum - p. 457 77. Abstract - p. 457 78. Generalities - p. 458 79. Inflammatory Diseases - p. 458 80. Cysts (Other Than Thymic) - p. 459 81. Thymus - p. 460 82. Malignant Lymphoma - p. 484 83. Neurogenic Tumors - p. 489 84. Tumors of Paraganglia - p. 490 85. Mesenchymal Tumors - p. 491 86. Metastatic Tumors - p. 492 87. References - p. 492 88. Section 4 Gastrointestinal and Hepatobiliary Tract - p. 500 89. 13 Esophagus - p. 502 90. 14 Stomach - p. 528 91. Abstract - p. 528 92. Normal Anatomy - p. 529 93. Heterotopic Tissues - p. 528.e1 94. Hypertrophic Pyloric Stenosis - p. 530 95. Chronic Gastritis - p. 530 96. Other Types of Gastritis - p. 532 97. Peptic and Other Benign Ulcers - p. 533 98. Other Non-Neoplastic Lesions - p. 535 99. Polyps - p. 536 100. Ménétrier Disease and Zollinger–Ellison Syndrome - p. 539 101. Regenerative Changes and Dysplasia - p. 539 102. Carcinoma - p. 541 103. Well-Differentiated Neuroendocrine Tumors (“Carcinoid Tumors”) - p. 548 104. Stromal Tumors (Gastrointestinal Stromal Tumors and Related Lesions) - p. 550 105. Lymphoid Tumors and Tumorlike Conditions - p. 553 106. Other Tumors - p. 557 107. References - p. 559 108. 15 Small Bowel - p. 568 109. Abstract - p. 568 110. Normal Anatomy - p. 569 111. Congenital Defects - p. 570 112. Inflammatory Disorders - p. 572 113. Polyps and Tumors - p. 590 114. References - p. 605 115. 16 Appendix - p. 617 116. 17 Large Bowel - p. 648 117. Abstract - p. 648 118. Normal Anatomy of the Large Bowel - p. 649 119. Hirschsprung Disease and Related Disorders - p. 648.e1 120. Diverticulosis - p. 651 121. Colitis - p. 652 122. Other Non-Neoplastic Lesions - p. 663 123. Tumors - p. 668 124. References - p. 689 125. 18 Anus - p. 703 126. 19 Liver - p. 726 127. Abstract - p. 726 128. Normal Anatomy - p. 727 129. Biopsy - p. 726.e1 130. Viral Hepatitis - p. 728 131. Drug-Induced and Toxic Liver Injury - p. 739 132. Steatosis and Steatohepatitis - p. 744 133. Cholestasis, Biliary Diseases, and Autoimmune Hepatitis - p. 750 134. Cirrhosis - p. 761 135. Childhood Disorders and Disorders of Metabolism - p. 762 136. Disorders of Copper and Iron Metabolism - p. 769 137. Fibropolycystic Diseases (Ductal Plate Malformation) - p. 772 138. Vascular Disorders - p. 775 139. Liver Disease in Pregnancy - p. 777 140. Liver Involvement in Systemic Diseases - p. 777 141. Liver Pathology in Organ Transplantation - p. 781 142. References - p. 785 143. 20 Liver - p. 803 144. Abstract - p. 803 145. Hepatic Tumors and Tumorlike Conditions - p. 804 146. Bile Duct Tumors and Tumorlike Conditions - p. 819 147. Mesenchymal Tumors and Tumorlike Conditions - p. 824 148. Malignant Lymphoma and Related Lesions - p. 829 149. Other Primary Tumors and Tumorlike Conditions - p. 831 150. Metastatic Tumors - p. 831 151. References - p. 833 152. 21 Gallbladder and Extrahepatic Bile Ducts - p. 844 153. 22 Pancreas and Ampullary Region - p. 886 154. Abstract - p. 886 155. Pancreas - p. 887 156. Ampullary Region - p. 921 157. References - p. 923 158. Volume 2 - p. 933 159. Section 5 Genitourinary Pathology - p. 933 160. 23 Kidney - p. 936 161. Abstract - p. 936 162. Renal Biopsy - p. 936.e1 163. Normal Structure of the Glomerulus - p. 938 164. Classification of Glomerular Disease - p. 940 165. Glomerular Lesions Associated With the Nephrotic Syndrome - p. 940 166. Glomerular Lesions Associated With the Syndrome of Acute Nephritis - p. 958 167. Glomerular Lesions Associated With Vascular Diseases - p. 973 168. Renal Diseases of Pregnancy - p. 979 169. Hereditary Glomerular Diseases - p. 980 170. Renal Transplant Pathology - p. 984 171. Tubulointerstitial Diseases - p. 989 172. Renal Vascular Disease - p. 995 173. Radiation Nephropathy - p. 998 174. Cystic Diseases of the Kidney - p. 998 175. References - p. 1002 176. 24 Kidney - p. 1014 177. Abstract - p. 1014 178. Pediatric Tumors and Tumorlike Conditions - p. 1015 179. Adult Tumors and Tumorlike Conditions - p. 1025 180. References - p. 1049 181. 25 Bladder - p. 1066 182. 26 Prostate and Seminal Vesicles - p. 1097 183. Abstract - p. 1097 184. Prostate - p. 1098 185. Prostatic Urethra - p. 1121 186. Seminal Vesicles and Cowper's Glands - p. 1121 187. References - p. 1122 188. 27 Testis and Testicular Adnexa - p. 1135 189. Abstract - p. 1135 190. Testis - p. 1136 191. Testicular Adnexa - p. 1157 192. References - p. 1164 193. 28 Penis and Scrotum - p. 1175 194. 29 Adrenal Gland and Other Paraganglia - p. 1190 195. Section 6 Female Reproductive System - p. 1221 196. 30 Vulva - p. 1224 197. 31 Vagina - p. 1248 198. 32 Uterus - p. 1260 199. Abstract - p. 1260 200. Normal Anatomy - p. 1261 201. Remnants and Ectopias - p. 1261 202. Squamous and Other Metaplasias - p. 1260.e1 203. Inflammatory Lesions - p. 1263 204. Non-Neoplastic Glandular Lesions - p. 1263 205. Non-Neoplastic Stromal Lesions (Including Endometriosis and Related Processes) - p. 1265 206. Human Papilloma Virus and the Lower Female Genital Tract - p. 1266 207. Tumors - p. 1267 208. References - p. 1284 209. 33 Uterus - p. 1294 210. Abstract - p. 1294 211. Normal Anatomy - p. 1295 212. Effects of Hormone Administration - p. 1296 213. Endometritis - p. 1297 214. Metaplasia - p. 1298 215. Adenomyosis and Endometriosis - p. 1300 216. Dysfunctional Uterine Bleeding - p. 1302 217. Endometrial Hyperplasia Without Atypia, Atypical Hyperplasia, and Variants - p. 1303 218. Curettage and Biopsy - p. 1305 219. Tumors - p. 1306 220. References - p. 1340 221. 34 Fallopian Tube - p. 1356 222. 35 Ovary - p. 1367 223. Abstract - p. 1367 224. Normal Anatomy - p. 1368 225. Gonadal Dysgenesis - p. 1367.e1 226. Cysts, Stromal Hyperplasia, and Other Non-Neoplastic Lesions - p. 1369 227. Inflammation - p. 1373 228. Endometriosis - p. 1374 229. Tumors - p. 1374 230. References - p. 1417 231. Section 7 Breast - p. 1431 232. 36 Breast - p. 1434 233. Abstract - p. 1434 234. Normal Anatomy - p. 1435 235. Ectopia - p. 1436 236. Inflammatory and Related Lesions - p. 1437 237. Benign Breast Disease - p. 1440 238. Intraductal Proliferative Lesions and Nonproliferative Changes - p. 1440 239. Fibroepithelial Lesions - p. 1447 240. Adenosis and Sclerosing Lesions - p. 1451 241. Papillary Lesions - p. 1456 242. Nipple Lesions - p. 1462 243. Carcinoma - p. 1464 244. Salivary Gland and Skin Adnexal-Type Tumors (Including Myoepithelial Tumors) - p. 1503 245. Stromal and Vascular Tumors and Tumorlike Conditions - p. 1504 246. Lymphoid Tumors and Tumorlike Conditions - p. 1506 247. Other Primary Tumors and Tumorlike Conditions - p. 1507 248. Metastatic Tumors - p. 1509 249. Breast Diseases in Children and Adolescents - p. 1510 250. Breast Diseases in Males - p. 1511 251. References - p. 1512 252. Section 8 Hematopathology - p. 1527 253. 37 Lymph Nodes - p. 1530 254. Abstract - p. 1530 255. Normal Anatomy - p. 1531 256. Lymph Node Evaluation - p. 1530.e1 257. Primary Immunodeficiencies - p. 1538 258. Patterns of Hyperplasia - p. 1539 259. Inflammatory/Hyperplastic Diseases - p. 1543 260. Malignant Lymphoma - p. 1561 261. Tumors of the Accessory Immune System - p. 1594 262. Vascular Tumors and Tumorlike Conditions - p. 1597 263. Other Primary Tumors and Tumorlike Conditions - p. 1598 264. Lymph Node Inclusions - p. 1601 265. Other Non-Neoplastic Lesions - p. 1604 266. Metastatic Tumors - p. 1605 267. References - p. 1610 268. 38 Spleen - p. 1632 269. 39 Bone Marrow - p. 1658 270. Abstract - p. 1658 271. Biopsy Procedure and Processing of Specimen - p. 1659 272. Immunohistochemistry - p. 1660 273. Normocellular Bone Marrow - p. 1662 274. Alterations in Cellularity - p. 1663 275. Osteopetrosis - p. 1665 276. Bone Marrow Necrosis - p. 1665 277. Inflammatory Disorders - p. 1666 278. Human Immunodeficiency Virus Syndrome (HIV, AIDS) - p. 1669 279. Leukemias and Related Disorders - p. 1670 280. Systemic Mastocytosis - p. 1684 281. Mature B-Cell Neoplasms - p. 1687 282. Non-Hodgkin Lymphoma - p. 1693 283. Benign Lymphocytic Aggregates - p. 1703 284. Hodgkin Lymphoma - p. 1704 285. Histiocytic Disorders - p. 1706 286. Plasma Cell Dyscrasias - p. 1709 287. Systemic Polyclonal B-Immunoblastic Proliferation - p. 1716 288. Metastatic Tumors - p. 1717 289. Lipid Storage Diseases - p. 1719 290. Hematopoietic Cell Transplantation - p. 1721 291. Acknowledgment - p. 1724 292. References - p. 1724 293. Section 9 Bone and Soft Tissue Pathology - p. 1737 294. 40 Bone and Joints - p. 1740 295. Abstract - p. 1740 296. Bone - p. 1741 297. Joints and Related Structures - p. 1789 298. References - p. 1797 299. 41 Soft Tissues - p. 1810 300. Abstract - p. 1810 301. Normal Anatomy - p. 1811 302. Infections and Hematomas - p. 1810.e1 303. Tumors - p. 1810.e1 304. References - p. 1892 305. Section 10 Cardiovascular Pathology - p. 1914 306. 42 Cardiovascular System - p. 1916 307. Section 11 Central Nervous System - p. 1945 308. 43 Central Nervous System - p. 1948 309. Abstract - p. 1948 310. Normal Anatomy - p. 1949 311. Developmental Abnormalities - p. 1948.e1 312. Cerebrovascular Disorders - p. 1955 313. Inflammatory Diseases - p. 1962 314. Infectious Diseases - p. 1967 315. Primary Tumors - p. 1977 316. Secondary/Metastatic Tumors - p. 2059 317. Acknowledgments - p. 2061 318. References - p. 2061 319. 44 Pituitary Gland - p. 2086 320. 45 Eye and Ocular Adnexa - p. 2112 321. Index - p. I-1

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