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In collaboration with Consulting Editor, Dr. Lucky Jain, Drs. Hamrick and Ing have put together a comprehensive issue that provides current information of anesthesia, sedation, and pain control in the NICU and for mothers. Clinical review articles are devoted to the following topics:  Anesthesia neurotoxicity in the developing brain: Basic studies; Anesthesia neurotoxicity: Update on clinical studies; Neurologic Injury after neonatal cardiac surgery; Effect of repetitive pain on developing brain and physiology of nociception; Sedation/pain control in the NICU; Assessment of Pain in the Newborn; Non-pharmacologic Approaches to Pain Management; Epidurals/spinals for newborn surgery; Neonatal airway management; Effects of maternal anesthesia on perinatal hemodynamics and neonatal acidemia; Maternal anesthesia for urgent c-section; Fetal anesthesia; Neonatal abstinence syndrome (Neonatal Opioid Withdrawal Syndrome); and Opioid crisis in the US: Maternal management. Readers will come away with the information they need to provide better care to the neonate and mothers and improve outcomes.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. CME Accreditation Page - p. xi 7. Forthcoming Issues - p. xiii 8. Foreword - p. xv 9. Preface - p. xvii 10. Human Studies of Anesthesia-Related Neurotoxicity in Children: A Narrative Review of Recent Additions to the Clinical Literature - p. 637 11. Anesthesia Neurotoxicity in the Developing Brain: Basic Studies Relevant for Neonatal or Perinatal Medicine - p. 647 12. Neurologic Injury in Neonates Undergoing Cardiac Surgery - p. 657 13. Pharmacology of Common Analgesic and Sedative Drugs Used in the Neonatal Intensive Care Unit - p. 673 14. Assessment of Pain in the Newborn: An Update - p. 693 15. Nonpharmacologic Management of Pain During Common Needle Puncture Procedures in Infants: Current Research Evidence and Practical Considerations: An Update - p. 709 16. Epidural and Spinal Anesthesia for Newborn Surgery - p. 731 17. Neonatal Airway Management - p. 745 18. Effects of Vasoactive Medications and Maternal Positioning During Cesarean Delivery on Maternal Hemodynamics and Neonatal Acid–Base Status - p. 765 19. Anesthesia for Urgent Cesarean Section - p. 785 20. Anesthesia for Fetal Surgery and Fetal Procedures - p. 801 21. Neonatal Abstinence Syndrome: Review of Epidemiology, Care Models, and Current Understanding of Outcomes - p. 817 22. Pain, Opioids, and Pregnancy: Historical Context and Medical Management - p. 833

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In collaboration with Consulting Editor, Dr. Lucky Jain, Drs. Hamrick and Ing have put together a comprehensive issue that provides current information of anesthesia, sedation, and pain control in the NICU and for mothers. Clinical review articles are devoted to the following topics:  Anesthesia neurotoxicity in the developing brain: Basic studies; Anesthesia neurotoxicity: Update on clinical studies; Neurologic Injury after neonatal cardiac surgery; Effect of repetitive pain on developing brain and physiology of nociception; Sedation/pain control in the NICU; Assessment of Pain in the Newborn; Non-pharmacologic Approaches to Pain Management; Epidurals/spinals for newborn surgery; Neonatal airway management; Effects of maternal anesthesia on perinatal hemodynamics and neonatal acidemia; Maternal anesthesia for urgent c-section; Fetal anesthesia; Neonatal abstinence syndrome (Neonatal Opioid Withdrawal Syndrome); and Opioid crisis in the US: Maternal management. Readers will come away with the information they need to provide better care to the neonate and mothers and improve outcomes.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. CME Accreditation Page - p. xi 7. Forthcoming Issues - p. xiii 8. Foreword - p. xv 9. Preface - p. xvii 10. Human Studies of Anesthesia-Related Neurotoxicity in Children: A Narrative Review of Recent Additions to the Clinical Literature - p. 637 11. Anesthesia Neurotoxicity in the Developing Brain: Basic Studies Relevant for Neonatal or Perinatal Medicine - p. 647 12. Neurologic Injury in Neonates Undergoing Cardiac Surgery - p. 657 13. Pharmacology of Common Analgesic and Sedative Drugs Used in the Neonatal Intensive Care Unit - p. 673 14. Assessment of Pain in the Newborn: An Update - p. 693 15. Nonpharmacologic Management of Pain During Common Needle Puncture Procedures in Infants: Current Research Evidence and Practical Considerations: An Update - p. 709 16. Epidural and Spinal Anesthesia for Newborn Surgery - p. 731 17. Neonatal Airway Management - p. 745 18. Effects of Vasoactive Medications and Maternal Positioning During Cesarean Delivery on Maternal Hemodynamics and Neonatal Acid–Base Status - p. 765 19. Anesthesia for Urgent Cesarean Section - p. 785 20. Anesthesia for Fetal Surgery and Fetal Procedures - p. 801 21. Neonatal Abstinence Syndrome: Review of Epidemiology, Care Models, and Current Understanding of Outcomes - p. 817 22. Pain, Opioids, and Pregnancy: Historical Context and Medical Management - p. 833

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