The field of Clinical Microbiology is evolving at a rapid pace, perhaps more so than any other arm of laboratory medicine. This can be attributed to new technology, including high throughput gene sequencing, multiplex molecular assays, rapid evolution of antimicrobial resistance, and discovery of new pathogens. In addition, modern medical procedures, such as solid organ and stem cell transplantation, have resulted in an explosion of infections with agents that historically have been considered to be of low virulence. This issue of Clinics in Laboratory Medicine will highlight some of the advances in diagnostic microbiology, including MALDI-TOF MS, pathogen discovery, and personalized antimicrobial chemotherapy. In addition, one of the papers will focus on implementation of new technologies and how to maximize patient impact of these new methods.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Contributors - p. 4 5. Forthcoming Issues - p. 7 6. Preface: Automation and Emerging Technology in Clinical Microbiology - p. 8 7. Laboratory Detection of Sepsis - p. 9 8. Molecular Detection of Respiratory Viruses - p. 19 9. Molecular Diagnostics and Parasitic Disease - p. 26 10. Invasive Fungal Infections - p. 45 11. Advanced Techniques for Detection and Identification of Microbial Agents of Gastroenteritis - p. 58 12. Molecular Approaches and Biomarkers for Detection of Mycobacterium tuberculosis - p. 73 13. Automation in the Clinical Microbiology Laboratory - p. 81 14. MALDI-TOF Mass Spectrometry for Microorganism Identification - p. 89 15. Beyond Identification - p. 99 16. Bacterial Strain Typing - p. 110 17. Diagnostic Assays for Identification of Microorganisms and Antimicrobial Resistance Determinants Directly from Positive Blood Culture Broth - p. 122 18. Future-Generation Sequencing and Clinical Microbiology - p. 134 19. Integration of Technology Into Clinical Practice - p. 147 20. Index - p. 157
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The field of Clinical Microbiology is evolving at a rapid pace, perhaps more so than any other arm of laboratory medicine. This can be attributed to new technology, including high throughput gene sequencing, multiplex molecular assays, rapid evolution of antimicrobial resistance, and discovery of new pathogens. In addition, modern medical procedures, such as solid organ and stem cell transplantation, have resulted in an explosion of infections with agents that historically have been considered to be of low virulence. This issue of Clinics in Laboratory Medicine will highlight some of the advances in diagnostic microbiology, including MALDI-TOF MS, pathogen discovery, and personalized antimicrobial chemotherapy. In addition, one of the papers will focus on implementation of new technologies and how to maximize patient impact of these new methods.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Contributors - p. 4 5. Forthcoming Issues - p. 7 6. Preface: Automation and Emerging Technology in Clinical Microbiology - p. 8 7. Laboratory Detection of Sepsis - p. 9 8. Molecular Detection of Respiratory Viruses - p. 19 9. Molecular Diagnostics and Parasitic Disease - p. 26 10. Invasive Fungal Infections - p. 45 11. Advanced Techniques for Detection and Identification of Microbial Agents of Gastroenteritis - p. 58 12. Molecular Approaches and Biomarkers for Detection of Mycobacterium tuberculosis - p. 73 13. Automation in the Clinical Microbiology Laboratory - p. 81 14. MALDI-TOF Mass Spectrometry for Microorganism Identification - p. 89 15. Beyond Identification - p. 99 16. Bacterial Strain Typing - p. 110 17. Diagnostic Assays for Identification of Microorganisms and Antimicrobial Resistance Determinants Directly from Positive Blood Culture Broth - p. 122 18. Future-Generation Sequencing and Clinical Microbiology - p. 134 19. Integration of Technology Into Clinical Practice - p. 147 20. Index - p. 157
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