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This issue of Endocrinology and Metabolism Clinics, guest edited by Drs. Caroline M. Apovian and Nawfal Istfan, is devoted to Obesity. Articles in this comprehensive issue include: Guidelines for Obesity Management; Obesity is a Disease; Pharmacotherapy for Obesity; Bariatric Surgery Mechanisms; Diabetes Treatment in the Patient with Obesity; Adipose Tissue: Inflammation and the Endocrine Organ; Behavioral Treatment of the Patient with Obesity; The Role of Macronutrient Content in the Diet for Weight Loss and Weight Maintenance; Substrate Oxidation and Brown Adipose Tissue; Brown and Beige Adipose Tissue: Therapy for Obesity?; Ethnic Differences in Diabetes Lipids HTN and Obesity; Genetics of Bariatric Surgery Outcomes; Leptin and Hormones: Energy Homeostatis; Bariatric Surgery Clinical Outcomes; Medical Devices for Obesity; Adolescent Bariatric Surgery; Psychological Aspects of Obesity; and Nutrient Timing.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xii 7. Foreword - p. xiii 8. Preface - p. xvii 9. Guidelines for Obesity Management - p. 501 10. Regarding Obesity as a Disease: Evolving Policies and Their Implications - p. 511 11. Pharmacotherapy for Obesity - p. 521 12. Potential Mechanisms Mediating Sustained Weight Loss Following Roux-en-Y Gastric Bypass and Sleeve Gastrectomy - p. 539 13. Type 2 Diabetes Treatment in the Patient with Obesity - p. 553 14. Behavioral Treatment of the Patient with Obesity - p. 565 15. The Role of Macronutrient Content in the Diet for Weight Management - p. 581 16. Brown and Beige Adipose Tissue: Therapy for Obesity and Its Comorbidities? - p. 605 17. Genetics of Bariatric Surgery Outcomes - p. 623 18. Leptin and Hormones: Energy Homeostasis - p. 633 19. Bariatric Surgery: Overview of Procedures and Outcomes - p. 647 20. Medical Devices in the Treatment of Obesity - p. 657 21. Update on Adolescent Bariatric Surgery - p. 667 22. The Psychosocial Burden of Obesity - p. 677 23. Energy and Nutrient Timing for Weight Control: Does Timing of Ingestion Matter? - p. 689 24. Index - p. 719

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This issue of Endocrinology and Metabolism Clinics, guest edited by Drs. Caroline M. Apovian and Nawfal Istfan, is devoted to Obesity. Articles in this comprehensive issue include: Guidelines for Obesity Management; Obesity is a Disease; Pharmacotherapy for Obesity; Bariatric Surgery Mechanisms; Diabetes Treatment in the Patient with Obesity; Adipose Tissue: Inflammation and the Endocrine Organ; Behavioral Treatment of the Patient with Obesity; The Role of Macronutrient Content in the Diet for Weight Loss and Weight Maintenance; Substrate Oxidation and Brown Adipose Tissue; Brown and Beige Adipose Tissue: Therapy for Obesity?; Ethnic Differences in Diabetes Lipids HTN and Obesity; Genetics of Bariatric Surgery Outcomes; Leptin and Hormones: Energy Homeostatis; Bariatric Surgery Clinical Outcomes; Medical Devices for Obesity; Adolescent Bariatric Surgery; Psychological Aspects of Obesity; and Nutrient Timing.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xii 7. Foreword - p. xiii 8. Preface - p. xvii 9. Guidelines for Obesity Management - p. 501 10. Regarding Obesity as a Disease: Evolving Policies and Their Implications - p. 511 11. Pharmacotherapy for Obesity - p. 521 12. Potential Mechanisms Mediating Sustained Weight Loss Following Roux-en-Y Gastric Bypass and Sleeve Gastrectomy - p. 539 13. Type 2 Diabetes Treatment in the Patient with Obesity - p. 553 14. Behavioral Treatment of the Patient with Obesity - p. 565 15. The Role of Macronutrient Content in the Diet for Weight Management - p. 581 16. Brown and Beige Adipose Tissue: Therapy for Obesity and Its Comorbidities? - p. 605 17. Genetics of Bariatric Surgery Outcomes - p. 623 18. Leptin and Hormones: Energy Homeostasis - p. 633 19. Bariatric Surgery: Overview of Procedures and Outcomes - p. 647 20. Medical Devices in the Treatment of Obesity - p. 657 21. Update on Adolescent Bariatric Surgery - p. 667 22. The Psychosocial Burden of Obesity - p. 677 23. Energy and Nutrient Timing for Weight Control: Does Timing of Ingestion Matter? - p. 689 24. Index - p. 719

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