This issue will assist the practicing pediatrician with providing evidence-based care to children with common, rare, inherited and acquired hematological disorders whom they regularly see in general pediatric practice. The information in this edition will support a general pediatrician’s understanding of recently developed diagnostic and therapeutic tools--for instance, techniques for the assessment of transfusional iron overload in chronically transfused patients – resulting in better surveillance of medication side effects and improved support for patients who are prescribed with complex chelation regimens. New, improved therapeutic approaches to treatment of children with venous thromboembolic disease have recently been introduced; affected patients often require close monitoring in their communities through the general pediatrician whose practice will be enhanced by information that has been prepared by pediatric specialists with pediatric patients in mind.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. CME Accreditation Page and Author Disclosure - p. 4 5. Contributors - p. 5 6. Forthcoming Issues - p. 9 7. Pediatric Hematology - p. 10 8. Chapter 1: Development of the Hematopoietic System and Disorders of Hematopoiesis that Present During Infancy and Early Childhood - p. 11 9. Chapter 2: The Inherited Bone Marrow Failure Syndromes - p. 18 10. Chapter 3: Acquired Aplastic Anemia in Children - p. 30 11. Chapter 4: Hematologic Manifestations of Systemic Disease (Including Iron Deficiency, Anemia of Inflammation and DIC) - p. 41 12. Chapter 5: Abnormalities of the Erythrocyte Membrane - p. 47 13. Chapter 6: Sickle Cell Disease in Childhood - p. 54 14. Chapter 7: Thalassemias - p. 64 15. Chapter 8: Evaluation and Treatment of Transfusional Iron Overload in Children - p. 69 16. Chapter 9: Developmental Hemostasis - p. 74 17. Chapter 10: Inherited Abnormalities of Coagulation - p. 80 18. Chapter 11: Pediatric Thrombophilia - p. 92 19. Chapter 12: Antithrombotic Therapies - p. 104 20. Chapter 13: Inherited Disorders of Platelet Function - p. 111 21. Chapter 14: Diagnosis and Management of Autoimmune Cytopenias in Childhood - p. 117 22. Chapter 15: HUS and TTP in Children - p. 129 23. Chapter 16: Transfusion and Hemovigilance in Pediatrics - p. 137 24. Chapter 17: Blood Banking/Immunohematology - p. 145 25. Chapter 18: Pediatric Therapeutic Apheresis - p. 157 26. Index - p. 164
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This issue will assist the practicing pediatrician with providing evidence-based care to children with common, rare, inherited and acquired hematological disorders whom they regularly see in general pediatric practice. The information in this edition will support a general pediatrician’s understanding of recently developed diagnostic and therapeutic tools--for instance, techniques for the assessment of transfusional iron overload in chronically transfused patients – resulting in better surveillance of medication side effects and improved support for patients who are prescribed with complex chelation regimens. New, improved therapeutic approaches to treatment of children with venous thromboembolic disease have recently been introduced; affected patients often require close monitoring in their communities through the general pediatrician whose practice will be enhanced by information that has been prepared by pediatric specialists with pediatric patients in mind.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. CME Accreditation Page and Author Disclosure - p. 4 5. Contributors - p. 5 6. Forthcoming Issues - p. 9 7. Pediatric Hematology - p. 10 8. Chapter 1: Development of the Hematopoietic System and Disorders of Hematopoiesis that Present During Infancy and Early Childhood - p. 11 9. Chapter 2: The Inherited Bone Marrow Failure Syndromes - p. 18 10. Chapter 3: Acquired Aplastic Anemia in Children - p. 30 11. Chapter 4: Hematologic Manifestations of Systemic Disease (Including Iron Deficiency, Anemia of Inflammation and DIC) - p. 41 12. Chapter 5: Abnormalities of the Erythrocyte Membrane - p. 47 13. Chapter 6: Sickle Cell Disease in Childhood - p. 54 14. Chapter 7: Thalassemias - p. 64 15. Chapter 8: Evaluation and Treatment of Transfusional Iron Overload in Children - p. 69 16. Chapter 9: Developmental Hemostasis - p. 74 17. Chapter 10: Inherited Abnormalities of Coagulation - p. 80 18. Chapter 11: Pediatric Thrombophilia - p. 92 19. Chapter 12: Antithrombotic Therapies - p. 104 20. Chapter 13: Inherited Disorders of Platelet Function - p. 111 21. Chapter 14: Diagnosis and Management of Autoimmune Cytopenias in Childhood - p. 117 22. Chapter 15: HUS and TTP in Children - p. 129 23. Chapter 16: Transfusion and Hemovigilance in Pediatrics - p. 137 24. Chapter 17: Blood Banking/Immunohematology - p. 145 25. Chapter 18: Pediatric Therapeutic Apheresis - p. 157 26. Index - p. 164
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