Obesity is an epidemic with enormous health, economic and social burdens. Current drugs for obesity treatment are far from ideal in terms of efficacy and side effects. Reviews in this volume of Progress in Molecular Biology and Translational Science summarize current status in studies of a number of G protein-coupled receptors that were shown to be promising targets for obesity treatments. Some of these receptors also cause monogenic obesity in humans.
1. Cover image 2. Title page 3. Table of Contents 4. Copyright 5. Contributors 6. Preface 7. Chapter One. G Protein-Coupled Receptors as Regulators of Energy Homeostasis 8. Chapter Two. Ghrelin Receptor in Energy Homeostasis and Obesity Pathogenesis 9. Chapter Three. Obestatin Receptor in Energy Homeostasis and Obesity Pathogenesis 10. Chapter Four. Melanocortin-3 Receptors and Metabolic Homeostasis 11. Chapter Five. Melanocortin-4 Receptor in Energy Homeostasis and Obesity Pathogenesis 12. Chapter Six. G Protein-Coupled Estrogen Receptor in Energy Homeostasis and Obesity Pathogenesis 13. Chapter Seven. Free Fatty Acid Receptor GPR120 and Pathogenesis of Obesity and Type 2 Diabetes Mellitus 14. Chapter Eight. The Role of Cholecystokinin Receptors in the Short-Term Control of Food Intake 15. Chapter Nine. Adiponectin Receptors in Energy Homeostasis and Obesity Pathogenesis 16. Chapter Ten. The Role of Bombesin and Bombesin-Related Peptides in the Short-term Control of Food Intake 17. Index
Obesity is an epidemic with enormous health, economic and social burdens. Current drugs for obesity treatment are far from ideal in terms of efficacy and side effects. Reviews in this volume of Progress in Molecular Biology and Translational Science summarize current status in studies of a number of G protein-coupled receptors that were shown to be promising targets for obesity treatments. Some of these receptors also cause monogenic obesity in humans.
1. Cover image 2. Title page 3. Table of Contents 4. Copyright 5. Contributors 6. Preface 7. Chapter One. G Protein-Coupled Receptors as Regulators of Energy Homeostasis 8. Chapter Two. Ghrelin Receptor in Energy Homeostasis and Obesity Pathogenesis 9. Chapter Three. Obestatin Receptor in Energy Homeostasis and Obesity Pathogenesis 10. Chapter Four. Melanocortin-3 Receptors and Metabolic Homeostasis 11. Chapter Five. Melanocortin-4 Receptor in Energy Homeostasis and Obesity Pathogenesis 12. Chapter Six. G Protein-Coupled Estrogen Receptor in Energy Homeostasis and Obesity Pathogenesis 13. Chapter Seven. Free Fatty Acid Receptor GPR120 and Pathogenesis of Obesity and Type 2 Diabetes Mellitus 14. Chapter Eight. The Role of Cholecystokinin Receptors in the Short-Term Control of Food Intake 15. Chapter Nine. Adiponectin Receptors in Energy Homeostasis and Obesity Pathogenesis 16. Chapter Ten. The Role of Bombesin and Bombesin-Related Peptides in the Short-term Control of Food Intake 17. Index
