Hematopoietic Stem Cell Niche focuses on an individual organ, looking at the stem cells in the organ itself (if they exist), their niches, and how to use them alongside relevant methods and protocols. This series addresses stem cells during development, homeostasis, and disease/injury of the respective organs, presenting new developments, such as new data on disease and clinical applications. Specific chapters delve into the evolution of hematopoietic stem cell niches, the role of CNS in the regulation of HSCs, and targeting the bone marrow niche in hematological malignancies. In addition, video content illustrates protocols, transplantation techniques, and work with mice.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. vii 6. Preface - p. ix 7. Chapter One: Stroma Cell Niche Regulation During HSC Development - p. ix 8. Chapter Two: The Evolvement of Hematopoietic Stem Cell Niches - p. 16 9. Chapter Three: The Role of the CNS in the Regulation of HSCs - p. 34 10. Chapter Four: Imaging the Hematopoietic Stem Cell Niche - p. 57 11. Chapter Five: Mechanisms of Hematopoietic Stem and Progenitor Cells Bone Marrow Homing and Mobilization - p. 83 12. Chapter Six: Alterations of HSC Niche in Myeloid Malignancies - p. 121 13. Chapter Seven: Targeting the Bone Marrow Niche in Hematological Malignancies - p. 153
Hematopoietic Stem Cell Niche focuses on an individual organ, looking at the stem cells in the organ itself (if they exist), their niches, and how to use them alongside relevant methods and protocols. This series addresses stem cells during development, homeostasis, and disease/injury of the respective organs, presenting new developments, such as new data on disease and clinical applications. Specific chapters delve into the evolution of hematopoietic stem cell niches, the role of CNS in the regulation of HSCs, and targeting the bone marrow niche in hematological malignancies. In addition, video content illustrates protocols, transplantation techniques, and work with mice.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. vii 6. Preface - p. ix 7. Chapter One: Stroma Cell Niche Regulation During HSC Development - p. ix 8. Chapter Two: The Evolvement of Hematopoietic Stem Cell Niches - p. 16 9. Chapter Three: The Role of the CNS in the Regulation of HSCs - p. 34 10. Chapter Four: Imaging the Hematopoietic Stem Cell Niche - p. 57 11. Chapter Five: Mechanisms of Hematopoietic Stem and Progenitor Cells Bone Marrow Homing and Mobilization - p. 83 12. Chapter Six: Alterations of HSC Niche in Myeloid Malignancies - p. 121 13. Chapter Seven: Targeting the Bone Marrow Niche in Hematological Malignancies - p. 153